Citation Impact
Citing Papers
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics
2006
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization
2004 StandoutScience
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Inducible and reversible phenotypes in a novel mouse model of Friedreich’s Ataxia
2017
Regulation of growth differentiation factor 15 expression by intracellular iron
2008 StandoutNobel
Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
2009 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions
2013
The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation: An EPR study
2010
Imaging beyond the proteome
2012 StandoutNobel
Iron, Free Radicals, and Oxidative Injury
2004
Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis
2003
Molecular Alterations in a Mouse Cardiac Model of Friedreich Ataxia
2017
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
2009
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
Iron and copper metabolism
2005
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
2007
Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency
2009 Standout
Decreased Liver Hepcidin Expression in the Hfe Knockout Mouse
2002
Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function
2010
Balancing Acts
2004 Standout
Iron Overload in Human Disease
2012
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
2010
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Chronic kidney disease
2011 Standout
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
2005
Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome
2012
Hepcidin and iron homeostasis
2012
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Novel trihydroxamate‐containing peptides: Design, synthesis, and metal coordination
2006
Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization
2009
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
TGFβ in Cancer
2008 Standout
The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues
2007
Iron uptake and metabolism in the new millennium
2006
Molecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia
2013
Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
2006
Hepcidin, A New Iron Regulatory Peptide
2002
FRET-based ratiometric fluorescent probes for selective Fe3+ sensing and their applications in mitochondria
2013
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD
2010
Epigenetic modifications and human disease
2010 Standout
Hypoxia-inducible Factor-1 Deficiency Results in Dysregulated Erythropoiesis Signaling and Iron Homeostasis in Mouse Development
2006 StandoutNobel
Neurodegenerative diseases and oxidative stress
2004 Standout
The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis
2008
Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics
2011
Friedreich's Ataxia, No Changes in Mitochondrial Labile Iron in Human Lymphoblasts and Fibroblasts
2004
Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression
2005
SLC11 family of H + -coupled metal-ion transporters NRAMP1 and DMT1
2004
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia
2008
Anemia of Chronic Disease
2005 Standout
The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion
2011
Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease
2011
Iron Homeostasis and Its Interaction with Prolyl Hydroxylases
2009
PHYSIOLOGY AND MOLECULAR BIOLOGY OF DIETARY IRON ABSORPTION
2003
Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia
2012
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Thiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase Inhibitors
2009
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Inhibition of iron transport across human intestinal epithelial cells by hepcidin
2004
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Suppression of hepcidin during anemia requires erythropoietic activity
2006
Luminescent Chemodosimeters for Bioimaging
2012 Standout
A highly selective turn-on fluorescent probe for iron(ii) to visualize labile iron in living cells
2012
A new class of high-contrast Fe(ii ) selective fluorescent probes based on spirocyclized scaffolds for visualization of intracellular labile iron delivered by transferrin
2014
Normoxic Stabilization of Hypoxia-Inducible Factor-1α by Modulation of the Labile Iron Pool in Differentiating U937 Macrophages: Effect of Natural Resistance–Associated Macrophage Protein 1
2006 StandoutNobel
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis
2004
Novel di-2-pyridyl–derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment
2004
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
2003 Standout
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Iron: A New Target for Pharmacological Intervention in Neurodegenerative Diseases
2006
Thiosemicarbazones: The New Wave in Cancer Treatment
2009
Mutation in the Fe–S scaffold protein Isu bypasses frataxin deletion
2011
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Iron-Deficiency Anemia
2015 Standout
Novel “hybrid” iron chelators derived from aroylhydrazones and thiosemicarbazones demonstrate selective antiproliferative activity against tumor cells
2002
Systemic Iron Homeostasis
2013
The Mononuclear Molybdenum Enzymes
2014 Standout
ISCU(M108I) and ISCU(D39V) Differ from Wild-Type ISCU in Their Failure To Form Cysteine Desulfurase Complexes Containing Both Frataxin and Ferredoxin
2018
Alterations of systemic and muscle iron metabolism in human subjects treated with low-dose recombinant erythropoietin
2009
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Expression of alternative transcripts of ferroportin-1 during human erythroid differentiation.
2005
Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders
2005
Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease
2012
Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe
2013
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Effect of hepcidin on intestinal iron absorption in mice
2004
Regulation of Iron Metabolism by Hepcidin
2006
Chelators at the Cancer Coalface: Desferrioxamine to Triapine and Beyond
2006
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity
2006
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
2005
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
2004
Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice
2011 StandoutNobel
Works of E. Becker being referenced
Development of novel aroylhydrazone ligands for iron chelation therapy: 2-Pyridylcarboxaldehyde isonicotinoyl hydrazone analogs
1999
Development of potential iron chelators for the treatment of Friedreich’s ataxia: ligands that mobilize mitochondrial iron
2001
Frataxin: its role in iron metabolism and the pathogenesis of Friedreich's ataxia
2001
Identification of the di‐pyridyl ketone isonicotinoyl hydrazone (PKIH) analogues as potent iron chelators and anti‐tumour agents
2003
Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
2002
The biologically active iron chelators 2-pyridylcarboxaldehyde isonicotinoylhydrazone, 2-pyridylcarboxaldehyde benzoylhydrazone monohydrate and 2-furaldehyde isonicotinoylhydrazone
1999
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
2009
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation
2008
Hepcidin, the hormone of iron metabolism, is bound specifically to α-2-macroglobulin in blood
2009
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization
2002
Relationship between intestinal iron-transporter expression, hepatic hepcidin levels and the control of iron absorption
2002
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
2010