Citation Impact
Citing Papers
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation
2003
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Tumour-cell invasion and migration: diversity and escape mechanisms
2003 Standout
Binding of the NG2 Proteoglycan to Type VI Collagen and Other Extracellular Matrix Molecules
1996
MEX-5 and MEX-6 Function to Establish Soma/Germline Asymmetry in Early C. elegans Embryos
2000
CD4+ T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize β1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion
1998
The Sensation and Regulation of Interactions with the Extracellular Environment: The Cell Biology of Lymphocyte Adhesion Receptors
1990
Distinct cellular functions mediated by different VLA integrin α subunit cytoplasmic domains
1992
TGF-β1 Stimulates Expression of Keratinocyte Integrins During Re-Epithelialization of Cutaneous Wounds
1994
Inflammation and cancer
2002 StandoutNature
Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells
1990
CD44 is the principal cell surface receptor for hyaluronate
1990 Standout
Hyaluronan Metabolism in Skin
1994
Erythroid adhesion molecules in sickle cell disease: Effect of hydroxyurea
2008
Expression of normal and mutant avian integrin subunits in rodent cells [published erratum appears in J Cell Biol 1989 Oct;109(4 Pt 1):1187]
1989
Acute chest syndrome of sickle cell disease: new light on an old problem
2001
Sickle red blood cells stimulate endothelial cell production of eicosanoids and diacylglycerol
1996
Fibronectin and integrins in invasion and metastasis
1995
A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
1999 Standout
C. elegans Germ Cells Show Temperature and Age-Dependent Expression of Cer1, a Gypsy/Ty3-Related Retrotransposon
2012
POP-1 and Anterior–Posterior Fate Decisions in C. elegans Embryos
1998
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes
1991
Control of Leukocyte Integrin Activation
1993
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Expression of CD44 confers a new adhesive phenotype on transfected cells
1990
Molecular cloning of the human α6 integrin subunit
1991
Involvement of integrin alpha V gene expression in human melanoma tumorigenicity.
1992
BCR/ABL induces multiple abnormalities of cytoskeletal function.
1997
Developmentally regulated alternative splicing of Drosophila integrin PS2 α transcripts
1989
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Structure, function and biological properties of integrin ?v?3on human melanoma cells
1991
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α4β1
1990
The Hallmarks of Cancer
2000 Standout
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
Integrins and cancer
1996
Endothelial-Leukocyte Adhesion Molecules
1993
Platelet Membrane Glycoproteins: Functions in Cellular Interactions
1990
β1 Integrin‐mediated lymphocyte adherence to extracellular matrix is enhanced by phorbol ester treatment
1991
A role for the Drosophila neurogenic genes in mesoderm differentiation
1991 StandoutNobel
Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
1994 Standout
Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation
1990
Distinctive Integrin Expression in the Newly Forming Epidermis During Wound Healing in Humans
1993
Extracellular Matrix Molecules and their Receptors: Functions in Neural Development
1991
Cell-matrix contact structures
2001
Inhibition of Cell Migration by Abl Family Tyrosine Kinases through Uncoupling of Crk-CAS Complexes
2001
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Review: The Integrin αvβ3: Angiogenesis and Apoptosis
1995
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes
1990
Adhesion receptors of the immune system
1990 StandoutNature
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Sickle-cell disease
2010 Standout
Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronectin binding precedes α5β1 integrin loss from the cell surface
1990
Platelets and blood vessels: the adhesion event
1992
Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic
1989
A Novel Protease-docking Function of Integrin at Invadopodia
1999
Keratinocytes in Human Wounds Express αvβ6 Integrin
1996
Fibulin-5/DANCE is essential for elastogenesis in vivo
2002 StandoutNatureNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion
1991
The adhesion molecules of inflammation
1993
Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration
2001
A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells
1989
Laminin receptor on platelets is the integrin VLA-6
1988 Nature
staufen, a gene required to localize maternal RNAs in the Drosophila egg
1991 StandoutNobel
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo
1993 StandoutNobel
Differential regulation of airway epithelial integrins by growth factors.
1996
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis.
1992
Pro-collagenase-1 (Matrix Metalloproteinase-1) Binds the α2β1 Integrin upon Release from Keratinocytes Migrating on Type I Collagen
2001
Mammalian collagen IV
2008
Relationship between the clinical manifestations of sickle cell disease and the expression of adhesion molecules on white blood cells
2002
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
Linkage of Dominant Hereditary Spherocytosis to the Gene for the Erythrocyte Membrane-Skeleton Protein Ankyrin
1990 StandoutNobel
The Structure and Insertion of Integral Proteins in Membranes
1990
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Activation of β1 Integrins Induces Cell–Cell Adhesion
2001
Pharmacologic Modulation of Fetal Hemoglobin
2001
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
The Roles of Integrins and Extracellular Matrix Proteins in the Insulin-like Growth Factor I-stimulated Chemotaxis of Human Breast Cancer Cells
1996
Effects of β Subunit Cytoplasmic Domain Deletions on the Recruitment of the Integrin αvβ6 to Focal Contacts
1994
Expression of the Human Integrin β 6 Subunit in Alveolar Type II Cells and Bronchiolar Epithelial Cells Reverses Lung Inflammation in β 6 Knockout Mice
1998
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.
1991
Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1.
1992
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo.
1995
Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface.
1991
Phorbol ester stimulation increases sickle erythrocyte adherence to endothelium: a novel pathway involving alpha 4 beta 1 integrin receptors on sickle reticulocytes and fibronectin
1996
Cell type-specific integrin variants with alternative alpha chain cytoplasmic domains.
1991
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.
1994
Extracellular matrix alters PDGF regulation of fibroblast integrins.
1996
Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration.
1990
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates.
1990
Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea
1997
Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.
1990
Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets.
1989
Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling
1995
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.
1996
Anionic Polysaccharides Inhibit Adhesion of Sickle Erythrocytes to the Vascular Endothelium and Result in Improved Hemodynamic Behavior
1999
Binding of Hepatitis C Virus to CD81
1998 StandoutScienceNobel
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins.
1991
The integrin αvβ6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin
1998
The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
1989
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy
1996
Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.
1996
Modulation of vitronectin receptor binding by membrane lipid composition.
1990
The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin.
1994
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996 Standout
Alpha 2 beta 1 integrins from different cell types show different binding specificities.
1990
Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface.
1993
Monoclonal antibodies to αVβ3 (7E3 and LM609) inhibit sickle red blood cell–endothelium interactions induced by platelet-activating factor
2000
Laminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytes.
1991
Functional Hierarchy of Simultaneously Expressed Adhesion Receptors: Integrin α2β1 but Not CD44 Mediates MV3 Melanoma Cell Migration and Matrix Reorganization within Three-dimensional Hyaluronan-containing Collagen Matrices
1999
Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins.
1990
Multiple integrins mediate cell attachment to cytotactin/tenascin.
1993 Nobel
Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells.
1995
Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.
1993
Leukocyte-endothelial adhesion molecules
1994 Standout
Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.
1989
Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins
1989
Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.
1989
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Introduction: anti-adhesion therapy in sickle cell disease
2000
Fetal hemoglobin in sickle cell anemia: relationship to erythrocyte adhesion markers and adhesion
2001
Heparin inhibits the flow adhesion of sickle red blood cells to P-selectin
2002
Role of erythrocyte phosphatidylserine in sickle red cell–endothelial adhesion
2002
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Adhesion of Activated Platelets to Endothelial Cells: Evidence for a GPIIbIIIa-dependent Bridging Mechanism and Novel Roles for Endothelial Intercellular Adhesion Molecule 1 (ICAM-1), αvβ3 Integrin, and GPIbα
1998
Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin.
1991
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.
1988
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.
1989
Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.
1989
Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunit.
1991
Calcium as a potential physiological regulator of integrin-mediated cell adhesion
1991
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
1992 StandoutNobel
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.
1992
PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
1997 StandoutScience
Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.
1989
The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.
1989
Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction.
1997
Integrin-associated protein is an adhesion receptor on sickle red blood cells for immobilized thrombospondin
2001
Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.
1990
Characterization of the integrin alpha 8 subunit: a new integrin beta 1-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminae in chick embryos.
1991
Adhesion of sickle red blood cells and damage to interleukin-1 beta stimulated endothelial cells under flow in vitro
1996
Wound repair, keratinocyte activation and integrin modulation
1992
Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).
1996
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis
1999
Collective cell movement in primary melanoma explants: plasticity of cell-cell interaction, beta1-integrin function, and migration strategies.
2002
The major laminin receptor of mouse embryonic stem cells is a novel isoform of the alpha 6 beta 1 integrin.
1991
β1 Integrins Are Critically Involved in Neutrophil Locomotion in Extravascular Tissue In Vivo
1998
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Structure and function of the leukocyte adhesion molecules CD11/CD18
1990
Interactions between Growth Factors and Integrins: Latent Forms of Transforming Growth Factor-β Are Ligands for the Integrin αvβ1
1998
Expression and function of cell surface extracellular matrix receptors in mouse blastocyst attachment and outgrowth.
1988
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
IL-12 attenuates bleomycin-induced pulmonary fibrosis
2001
Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.
1991
Activation-dependent recognition by hematopoietic cells of the LDV sequence in the V region of fibronectin.
1992
Human alpha 2(VI) collagen gene. Heterogeneity at the 5'-untranslated region generated by an alternate exon.
1992
The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.
1990
Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains
1989 Science
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Isolation of mouse CD44 cDNA: structural features are distinct from the primate cDNA.
1989
Sickle reticulocytes adhere to VCAM-1
1995
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
1993 StandoutNobel
Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.
1991
Integrin heterodimer and receptor complexity in avian and mammalian cells.
1989
Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.
1988
Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells.
1991
Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.
1990
Surface relocation of alpha 6 beta 4 integrins and assembly of hemidesmosomes in an in vitro model of wound healing.
1991
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
A synthetic peptide derived from the carboxy terminus of the laminin A chain represents a binding site for the alpha 3 beta 1 integrin
1992
A novel fibronectin receptor with an unexpected subunit composition (alpha v beta 1).
1990
Works of E A Wayner being referenced
Interferon-alpha restores normal adhesion of chronic myelogenous leukemia hematopoietic progenitors to bone marrow stroma by correcting impaired beta 1 integrin receptor function.
1994
Effects of interferon-gamma on expression of cell surface receptors for collagen and deposition of newly synthesized collagen by cultured human lung fibroblasts.
1989
Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.
1994
Integrin alpha 4 beta 1 and glycoprotein IV (CD36) are expressed on circulating reticulocytes in sickle cell anemia
1993
The fibronectin receptor is organized by extracellular matrix fibronectin: implications for oncogenic transformation and for cell recognition of fibronectin matrices.
1989
Structural homology between lymphocyte receptors for high endothelium and class III extracellular matrix receptor.
1989
Isolation and DNA sequence of a cDNA clone encoding a lymphocyte adhesion receptor for high endothelium.
1989
Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons.
1991
Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1)
1993
Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.
1994
Alpha 4/beta 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes.
1992
Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.
1987
Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells.
1984
Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen
1992
The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.
1990
Integrin alpha 4 beta 1 and glycoprotein IV (CD36) are expressed on circulating reticulocytes in sickle cell anemia
1993
The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.
1989
The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex.
1988