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Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
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Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
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Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor
2013
Janus Kinase (Jak) Subcellular Localization Revisited
2004
The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits
1986
The Single Transmembrane Domains of ErbB Receptors Self-associate in Cell Membranes
2002
Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites.
1990
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance
2016
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Myasthenia Gravis
1988
Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation
1988 Nature
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Molecular mimicry and myasthenia gravis. An autoantigenic site of the acetylcholine receptor alpha-subunit that has biologic activity and reacts immunochemically with herpes simplex virus.
1989
The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis
1992
Specific immunotherapeutic strategy for myasthenia gravis: targeted antigen-presenting cells
1992
Strategies for Treatment of Myasthenia Gravisa
1993
The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies
1991
Functional architecture of the nicotinic acetylcholine receptor: A prototype of ligand-gated ion channels
1993
Structure of nicotinic acetylcholine receptors
1993
Oncogenic kinase signalling
2001 StandoutNature
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
2010
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Common West African HLA antigens are associated with protection from severe malaria
1991 StandoutNature
Marine natural products
1990 Standout
Marine natural products
2011
Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action
2008
The N-Terminal Domain of Janus Kinase 2 Is Required for Golgi Processing and Cell Surface Expression of Erythropoietin Receptor
2001
Multifarious Determinants of Cytokine Receptor Signaling Specificity
2014
Acetylcholine receptor-reactive T and B cells in myasthenia gravis and controls.
1991
Erythropoietin stimulates proliferation of human renal carcinoma cells
2000
Marine natural products
2009
Physicochemical and immunological studies of the N‐terminal domain
of the Torpedo acetylcholine receptor α‐subunit expressed in
Escherichia coli
1999
Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors
2000
The T‐Cell Repertoire in Myasthenia Gravis Involves Multiple Cholinergic Receptor Epitopes
1992
Jaks and stats in cytokine signaling
1997
Actions of neurotoxins (bungarotoxins, neosurugatoxin and lophotoxins) on insect and nematode nicotinic acetylcholine receptors
1995
Turning cells red: signal transduction mediated by erythropoietin
2005
Myasthenia Gravis
1994 Standout
The Expression of EPOR in Renal Cortex during Postnatal Development
2012
A family of cytokine-inducible inhibitors of signalling
1997 StandoutNature
T cell recognition as the target for immune intervention in autoimmune disease
1989
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Acetylcholine interactions with tryptophan‐184 of the α‐subunit of the nicotinic acetylcholine receptor revealed by transferred nuclear Overhauser effect
1991
Erythropoietin Receptor Contains both Growth‐promoting Activity and Differentiation‐promoting Activitya
1994
A new pyrimidinedione derivative from the gorgonian coralVerrucella umbraculum
2012
Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models
2017
Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins
1995
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
The Erythropoietin Receptor Transmembrane Domain Mediates Complex Formation with Viral Anemic and Polycythemic gp55 Proteins
2003
Emerging structure of the Nicotinic Acetylcholine receptors
2002
Regulation of neurotransmitter receptor desensitization by protein phosphorylation
1990
T‐Helper Epitopes on Human Nicotinic Acetylcholine Receptor in Myasthenia Gravisa
1993
Protein modules and signalling networks
1995 StandoutNature
NMR structure of human erythropoietin and a comparison with its receptor bound conformation
1998
Humoral Pathogenesis of Myasthenia Grayisa
1987
Erythropoietin as a Retinal Angiogenic Factor in Proliferative Diabetic Retinopathy
2005
Diterpenes from gorgonian corals
2009
Molecular biology of erythropoietin
1993 StandoutNobel
Molecular Biology of Nicotinic Acetylcholine Receptors
1987
Amino acids of the Torpedo marmorata acetylcholine receptor .alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site
1988
Different HLA DR-DQ associations in subgroups of idiopathic myasthenia gravis
1990
Saturation Mutagenesis of the WSXWS Motif of the Erythropoietin Receptor
1996
The ligand binding domain of the nicotinic acetylcholine receptor
1993
T cells from normal and myasthenic individuals recognize the human acetylcholine receptor: Heterogeneity of antigenic sites on the α‐subunit
1992
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
1995
Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
1996 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Orientation‐specific signalling by thrombopoietin receptor dimers
2011
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
2001 StandoutNature
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
The molecular mechanism of erythropoietin action
1992
Cytokine receptor signalling
1995 Nature
Anemia of Chronic Disease
2005 Standout
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
1998 Nature
Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis.
1993
Murine Pluripotent Hematopoietic Progenitors Constitutively Expressing a Normal Erythropoietin Receptor Proliferate in Response to Erythropoietin without Preferential Erythroid Cell Differentiation
1994
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system
1987
Dissecting racial bias in an algorithm used to manage the health of populations
2019 StandoutScience
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris.
1989
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
JAK2 activation by growth hormone and other cytokines
2015
New Approaches to Olefin Cross-Metathesis
1999 StandoutNobel
Cyanogen Bromide Cleavage Generates Fragments Suitable for Expressed Protein and Glycoprotein Ligation
2004 StandoutNobel
Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor.
1994
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å
1996 Science
Conservation of neural nicotinic acetylcholine receptors from Drosophila to vertebrate central nervous systems.
1988
Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
1989 StandoutNature
Lophotoxins: Irreversible active‐site‐directed inhibitors of nicotinic acetylcholine receptors
1991
Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein
1991 StandoutScience
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore
1996 StandoutScience
The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells
1994
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Isolation, Structural Elucidation, and Absolute Stereochemistry of Enigmazole A, a Cytotoxic Phosphomacrolide from the Papua New Guinea Marine Sponge Cinachyrella enigmatica
2010
Genes expressed in the brain define three distinct neuronal nicotinic acetylcholine receptors.
1988
Murine pluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation.
1994
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Activation and differentiation requirements of primary T cells in vitro.
1993 StandoutNobel
Microbial metabolites: 45 years of wandering, wondering and discovering
2011 StandoutNobel
Natural Product Chemistry of Gorgonian Corals of the Family Plexauridae Distributed in the Indo-Pacific Ocean
2012
Primary familial polycythemia: a frameshift mutation in the erythropoietin receptor gene and increased sensitivity of erythroid progenitors to erythropoietin
1995
A mouse model for visualization and conditional mutations in the erythroid lineage
2004
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
1996 StandoutScience
β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization
1993 StandoutScienceNobel
Neural Science
2000 StandoutNobel
Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes
2010
Proliferation and erythroid differentiation through the cytoplasmic domain of the erythropoietin receptor.
1994
Mechanistic Diversity of Cytokine Receptor Signaling Across Cell Membranes
2004
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membrane
2014
Polycythemia vera: myths, mechanisms, and management
2002
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Specific Inhibition of Stat3 Signal Transduction by PIAS3
1997 StandoutScience
Dimerization of the Erythropoietin Receptor Transmembrane Domain in Micelles
2006
Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel
1986 StandoutNatureNobel
Solution-phase combinatorial synthesis: Convergent multiplication of diversity via the olefin metathesis reaction
1998
Phorbaketals A, B, and C, Sesterterpenoids with a Spiroketal of Hydrobenzopyran Moiety Isolated from the Marine Sponge Phorbas sp.
2009
Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies
1996
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
1988 StandoutNatureNobel
Sequence and functional expression of a single alpha subunit of an insect nicotinic acetylcholine receptor.
1990
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Gukulenins A and B, Cytotoxic Tetraterpenoids from the Marine Sponge Phorbas gukulensis
2010
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Thiazole and Oxazole Alkaloids: Isolation and Synthesis
2010
Caenorhabditis elegansLevamisole Resistance Geneslev-1,unc-29, andunc-38Encode Functional Nicotinic Acetylcholine Receptor Subunits
1997 StandoutNobel
Works of Drorit Neumann being referenced
Synthetic Peptides and Their Antibodies in the Analysis of the Acetylcholine Receptora
1987
Cellular aspects of myasthenia gravis
1988
In vitro proliferative responses and antibody titers specific to human acetylcholine receptor synthetic peptides in patients with myasthenia gravis and relation to HLA class II genes.
1988
A Functional Green Fluorescent Protein-tagged Erythropoietin Receptor Despite Physical Separation of JAK2 Binding Site and Tyrosine Residues
2002
Macrophages as novel target cells for erythropoietin
2010
Increased levels of acetylcholine receptor α‐subunit mRNA in experimental autoimmune myasthenia gravis
1988
Erythropoietin enhances Kupffer cell number and activity in the challenged liver
2017
A cytosolic domain of the erythropoietin receptor contributes to endoplasmic reticulum‐associated degradation
1999
Tausalarin C: A New Bioactive Marine Sponge-Derived Nitrogenous Bismacrolide
2009
Intracellular Retention and Degradation of the Epidermal Growth Factor Receptor, Two Distinct Processes Mediated by Benzoquinone Ansamycins
2000
Taumycins A and B, Two Bioactive Lipodepsipeptides from the Madagascar Sponge Fascaplysinopsis sp.
2008
Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor [see comments]
1993
Analysis of ligand binding to the synthetic dodecapeptide 185-196 of the acetylcholine receptor alpha subunit.
1986
Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor
2001
Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models
2001
Analysis of acetylcholine receptor phosphorylation sites using antibodies to synthetic peptides and monoclonal antibodies.
1986
Antibodies to synthetic peptides as probes for the binding site on the alpha subunit of the acetylcholine receptor.
1985
Nuttingins A−F and Malonganenones D−H, Tetraprenylated Alkaloids from the Tanzanian Gorgonian Euplexaura nuttingi
2007
Mapping of the alpha-bungarotoxin binding site within the alpha subunit of the acetylcholine receptor.
1986
Salarins A and B and Tulearin A: New Cytotoxic Sponge-Derived Macrolides
2007
Salarin C, a new cytotoxic sponge-derived nitrogenous macrolide
2008
Localization of a highly immunogenic region on the acetylcholine receptor α-subunit
1986
Mutations in the Trp-Ser-X-Trp-Ser motif of the erythropoietin receptor abolish processing, ligand binding, and activation of the receptor.
1992
Structure, function, and activation of the erythropoietin receptor
1993
Phosphorylation of the acetylcholine receptor by protein kinase C and identification of the phosphorylation site within the receptor delta subunit.
1987
Anti-acetylcholine receptor response achieved by immunization with a synthetic peptide from the receptor sequence
1984
Phosphorylation of erythropoietin receptors in the endoplasmic reticulum by pervanadate-mediated inhibition of tyrosine phosphatases
1997
How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor.
1992
Proliferative responses to acetylcholine receptor peptides in myasthenia gravis
1987
Mapping of the cAMP-dependent phosphorylation sites on the acetylcholine receptor.
1986
Snake acetylcholine receptor: cloning of the domain containing the four extracellular cysteines of the alpha subunit.
1989
Blocking intracellular degradation of the erythropoietin and asialoglycoprotein receptors by calpain inhibitors does not result in the same increase in the levels of their membrane and secreted forms
1996
Salarins D–J, seven new nitrogenous macrolides from the madagascar sponge Fascaplysinopsis sp.
2010
Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes
1993
Structure, function, and activation of the erythropoietin receptor
1993