Citation Impact
Citing Papers
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A
2008 StandoutNobel
Phenylpyropene A and B, New Inhibitors of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium griseofulvum F1959.
2002
Visible‐Light‐Induced Formal [3+2] Cycloaddition for Pyrrole Synthesis under Metal‐Free Conditions
2014
Tumor detection using 18F-labeled matrix metalloproteinase-2 inhibitor
2003
Role of Niemann-Pick Type C1 Protein in Intracellular Trafficking of Low Density Lipoprotein-derived Cholesterol
2000
Potential therapeutics for obesity and atherosclerosis: Inhibitors of neutral lipid metabolism from microorganisms
2007 StandoutNobel
Acyl CoA
1998
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
2014 Standout
New approaches to atherosclerosis: An overview
1993
Enantioselective Synthesis of Allylboronates and Allylic Alcohols by Copper‐Catalyzed 1,6‐Boration
2014
Phenylpyropene C, a New Inhibitor of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium griseofulvum F1959.
2002
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Chemical Modification and Structure-activity Relationships of Pyripyropenes. 1. Modification at the Four Hydroxyl Groups.
1996 StandoutNobel
ECM remodeling in hypertensive heart disease
2007
First systematic chiral syntheses of two pairs of enantiomers with 3,5-dihydroxyheptenoic acid chain, associated with a potent synthetic statin NK-104
1999
Synthesis and biological evaluations of quinoline-based HMG-CoA reductase inhibitors
2001
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Fluorine in Medicinal Chemistry
2015
Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors
2007
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells
2005 StandoutNobel
1 The Discovery and Development of Atorvastatin, A Potent Novel Hypolipidemic Agent
2002
A Powerful Brønsted Acid Catalyst for the Organocatalytic Asymmetric Transfer Hydrogenation of Imines
2005 StandoutNobel
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
The Diaryl(oxy)methyl Group: More than an Innocent Bystander in Chiral Auxiliaries, Catalysts, and Dopants
2012
Recent advances in MMP inhibitor design
2006
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Pyripyropenes, novel inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. I. Production, isolation, and biological properties.
1994 StandoutNobel
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1
2000
ACAT-2, A Second Mammalian Acyl-CoA:Cholesterol Acyltransferase
1998
GERI-BP001 Compounds, New Inhibitors of Acyl-CoA: Cholesterol Acyltransferase from Aspergillus fumigatus F37. I. Production, Isolation, and Physico-chemical and Biological Properties.
1995
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Inhibition of acyl-CoA: cholesterol acyltransferase in chinese hamster ovary (CHO) cells by short-chain ceramide and dihydroceramide
1995
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages
2001
Catalytic Asymmetric Synthesis of Phosphine Boronates
2015 StandoutNobel
Towards High‐Performance Lewis Acid Organocatalysis
2014 StandoutNobel
Atherosclerosis
2000 StandoutNature
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Atherosclerosis
2001 Standout
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Concise and highly efficient approach to three key pyrimidine precursors for rosuvastatin synthesis
2012
Natural Product-like Combinatorial Libraries Based on Privileged Structures. 1. General Principles and Solid-Phase Synthesis of Benzopyrans
2000
Fluorine in medicinal chemistry
2007 Standout
Chemical modification and structure-activity relationships of pyripyropenes; potent, bioavailable inhibitor of acyl-CoA: Cholesterol O-acyltransferase (ACAT)
1995 StandoutNobel
Liver-Specific Inhibition of Acyl-Coenzyme A:Cholesterol Acyltransferase 2 With Antisense Oligonucleotides Limits Atherosclerosis Development in Apolipoprotein B100–Only Low-Density Lipoprotein Receptor −/− Mice
2006
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Organic Photoredox Catalysis
2016 Standout
Electrosynthesis of 4-iodopyrazole and its derivatives
2010
Bioisosterism: A Rational Approach in Drug Design
1996
Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. 2. Identification and Structure−Activity Relationships of a Novel Series of N-Alkyl-N-(heteroaryl-substituted benzyl)-N‘-arylureas
1998
Pyripyropene A, an Acyl–Coenzyme A:Cholesterol Acyltransferase 2–Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia
2011 StandoutNobel
Total Synthesis of α-Pyrone Meroterpenoids, Novel Bioactive Microbial Metabolites
2005 StandoutNobel
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Matrix Metalloproteinases
2002
Die Diaryl(oxy)methyl‐Gruppe: mehr als ein unbeteiligter Zuschauer in chiralen Auxiliaren, Katalysatoren und Dotierstoffen
2012
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: Evidence suggesting multiple cholesterol esterification enzymes in mammals
1996
Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis
2004 StandoutNobel
ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver
2004 StandoutNobel
Chiral Proton Catalysis: A Catalytic Enantioselective Direct Aza-Henry Reaction
2004
C−H Bonds as Ubiquitous Functionality: A General Approach to Complex Arylated Pyrazoles via Sequential Regioselective C-Arylation and N-Alkylation Enabled by SEM-Group Transposition
2009
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages
2004
New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-Acylation/Cyclization
1997 StandoutNobel
Enantioselective Synthesis of Allylboronates and Allylic Alcohols by Copper‐Catalyzed 1,6‐Boration
2014
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
A formal synthesis of (+)-pyripyropene A using a biomimetic epoxy-olefin cyclisation: effect of epoxy alcohol/ether on cyclisation efficiency
1999
Toxicologic Effects of a Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor in Cynomolgus Monkeys
1994
Science and technology for water purification in the coming decades
2008 StandoutNature
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
A novel synthetic method of HMG-CoA reductase inhibitor NK-104 via a hydroboration-cross coupling sequence
1993
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Discovery of 1-(4-Fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)- hydroxypropyl]-(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235): A Designed, Potent, Orally Active Inhibitor of Cholesterol Absorption
1998
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Einführung von Fluor und fluorhaltigen funktionellen Gruppen
2013
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors
1996
Lactone Pathway to Statins Utilizing the Wittig Reaction. The Synthesis of Rosuvastatin
2010
Fluorine in health care: Organofluorine containing blockbuster drugs
2010 Standout
Efficient Total Synthesis of Novel Bioactive Microbial Metabolites
2008 StandoutNobel
A New Approach to the Total Synthesis of Rosuvastatin
2007
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
GERI-BP001, a new inhibitor of acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus F37
1994
Sulfamic Acid and Its N- and O-Substituted Derivatives
2013
Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.
1993
Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules
2000
Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption
2004 StandoutScience
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
The Discovery of Ezetimibe: A View from Outside the Receptor
2003
Works of Drago R. Sliskovic being referenced
Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. 8. Incorporation of Amide or Amine Functionalities into a Series of Disubstituted Ureas and Carbamates. Effects on ACAT Inhibition in vitro and Efficacy in vivo
1994
Inhibitors of cholesterol biosynthesis. 2. 1,3,5-Trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles
1990
Inhibitors of Acyl-CoA:cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents.6.The First Water-Soluble ACAT Inhibitor with Lipid-Regulating Activity
1994
Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus
1991
Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted-pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones
1992
Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cholesterol-fed rabbits: a biochemical and morphological evaluation
1994
3 ACAT Inhibitors: The Search for a Novel and Effective Treatment of Hypercholesterolemia and Atherosclerosis
2002
Inhibitors of cholesterol biosynthesis. 4. trans-6-[2-(Substituted-quinolinyl)ethenyl/ethyl]tetrahydro-4-hydroxy-2H-pyran-2-ones, a novel series of HMG-CoA reductase inhibitors
1991
Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents
1991
Inhibitors of cholesterol biosynthesis. 1. trans-6-(2-Pyrrol-1-ylethyl)-4-hydroxypyran-2-ones, a novel series of HMG-CoA reductase inhibitors. 1. Effects of structural modifications at the 2- and 5-positions of the pyrrole nucleus
1990
Matrix Metalloproteinase Inhibition Attenuates Left Ventricular Remodeling and Dysfunction in a Rat Model of Progressive Heart Failure
2001
Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. CI-1011: An Acyl Sulfamate with Unique Cholesterol-Lowering Activity in Animals Fed Noncholesterol-Supplemented Diets
1996
Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. Synthesis and Pharmacological Activity of (±)-2-Dodecyl-α-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5-acetamide and Structurally Related Tetrazole Amide Derivatives
1996
Section Review—Cardiovascular & Renal: Emerging Therapies in Atherosclerosis
1995
Inhibitors of Acyl-CoA:CholesterolO-Acyltransferase. 17. Structure−Activity Relationships of Several Series of Compounds Derived fromN-Chlorosulfonyl Isocyanate
1996
Structure−Activity Relationships and Pharmacokinetic Analysis for a Series of Potent, Systemically Available Biphenylsulfonamide Matrix Metalloproteinase Inhibitors
2000
Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. The synthesis and biological activity of a series of malonester amides
1996
α-Substituted Malonester Amides: Tools To Define the Relationship between ACAT Inhibition and Adrenal Toxicity
1998