Standout Papers
Citation Impact
Citing Papers
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
Evidence that excitatory amino acids not only activate the receptor channel complex but also lead to use-dependent block
1986
Ionotropic Glutamate Receptors & CNS Disorders
2008
The role of cyclic nucleotides in central synaptic function
1975
The action of β-phenyl-GABA derivatives on neurones of the cat cerebral cortex
1974
Molecular pharmacology of the opioid receptors
1995
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Coordination of entorhinal–hippocampal ensemble activity during associative learning
2014 StandoutNatureNobel
Chaotropic Ions Affect the Conformation of Quisqualate Receptors in Rat Cortical Membranes
1988
Regulation of calcium influx by second messengers in rat mast cells
1988 StandoutNatureNobel
Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists
1990
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
A specific quisqualate agonist inhibits kainate responses induced in Xenopus oocytes injected with rat brain RNA
1989
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+
1990 StandoutNobel
Structure/activity relations of N-methyl-d-aspartate receptor ligands as studied by their inhibition of [3H]d2-amino-5-phosphonopentanoic acid binding in rat brain membranes
1988
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System
1989 Standout
Thiocyanate stabilizes AMPA binding to the quisqualate receptor
1988
l-Homocysteate is a potent neurotoxin on cultured cortical neurons
1987
Toxins which produce pain
1975
Glutamate receptor desensitization and its role in synaptic transmission
1989
Mechanism of anion permeation through channels gated by glycine and gamma‐aminobutyric acid in mouse cultured spinal neurones.
1987 StandoutNobel
Structure of the δ-opioid receptor bound to naltrindole
2012 StandoutNatureNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
2009 Nature
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Repetitive stimulation at the mammalian neuromuscular junction, and the mobilization of transmitter
1963
Is Glycine a Neurotransmitter ?: Inhibition of Motoneurones by Iontophoresis of Glycine
1967 Nature
Associative Learning in Aplysia : Evidence for Conditioned Fear in an Invertebrate
1981 StandoutScienceNobel
On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds
1983
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K + Channel
1991 StandoutScienceNobel
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Ontogeny of adenosine 3?,5?-monophosphate metabolism in guinea pig cerebral cortex
1987
“Epileptic” brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine
1985
Habituation: A model phenomenon for the study of neuronal substrates of behavior.
1966 Standout
Anatomical distributions of four pharmacologically distinct 3H-L-glutamate binding sites
1983 Nature
AMPA, kainate, and quisqualate activate a common receptor-channel complex on embryonic chick motoneurons
1988
Neurones in a discrete region of the nucleus tractus solitarius are required for the Breuer‐Hering reflex in rat.
1990
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Selective depression of excitatory amino acid induced depolarizations by magnesium ions in isolated spinal cord preparations.
1980
Comparison of specificity of agonist and antagonist radioligand binding to β adrenergic receptors
1977 StandoutNatureNobel
Neurotransmitters as developmental signals
1991
Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.
1989
Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor
1989 StandoutNatureNobel
Baclofen and muscimol: Behavioural and neurochemical sequelae of unilateral intranigral administration and effects on 3H-GABA receptor binding
1979
Aspects of the molecular pharmacology of GABAB receptors
1991
Glutamate neurotoxicity in cortical cell culture
1987
Zinc Selectively Blocks the Action of N -Methyl-D-Aspartate on Cortical Neurons
1987 Science
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
The physiology and pharmacology of hippocampal formation theta rhythms
1986
The Coupling of Neurotransmitter Receptors to Ion Channels in the Brain
1988 Science
Mechanisms underlying epileptiform burst discharge
1980
Direct identification and characterisation of β-adrenergic receptors in rat brain
1975 StandoutNatureNobel
Glycine potentiates the NMDA response in cultured mouse brain neurons
1987 StandoutNature
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
The effects of intrahippocampal ibotenic acid and their blockade by (?) 2-amino-7-phosphonoheptanoic acid: Morphological and electroencephalographical analysis
1983
Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism
1976 StandoutNatureNobel
Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain
1984 StandoutScience
Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis
1971
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
1978 Nature
Inhibition of Na+‐independent [3H]GABA binding to synaptic membranes of rat brain by β‐substituted GABA derivatives
1979
Morphology and intracortical projections of functionally characterised neurones in the cat visual cortex
1979 StandoutNatureNobel
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Spider toxin (JSTX) blocks glutamate synapse in hippocampal pyramidal neurons
1985
The antagonism of amino acid‐induced excitations of rat hippocampal CA1 neurones in vitro.
1983
Gamma-Aminobutyric Acid Binding to Receptor Sites in the Rat Central Nervous System
1974
3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain
1981 StandoutNature
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system
1971
Molecular Structure and Physiological Function of Chloride Channels
2002
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Depressant actions of γ-d-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord
1985
Cellular bases of hippocampal EEG in the behaving rat
1983
Factors Modulating Brain Serotonin Turnover
1968
The Glycine Synaptic Receptor: Evidence That Strychnine Binding Is Associated with the Ionic Conductance Mechanism
1974
NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
1986 Nature
Differential regulation of the α2-adrenergic receptor by Na+ and guanine nucleotides
1980 StandoutNatureNobel
The contribution of inhibitory mechanisms to the receptive field properties of neurones in the striate cortex of the cat.
1975
α-Noradrenergic receptors in the brain: differential effects of sodium on binding of [3H]agonists and [3H]antagonists
1978
Wirkung von Tetrodotoxin und Tetra�thylammoniumchlorid an der Innenseite der Schn�rringsmembran vonXenopus laevis
1969
The Use of Degeneration Methods in the Investigation of Short Neuronal Connexions
1965
Relationship of Glucose Metabolism to Adrenergic Transmission in Rat Mesenteric Arteries
1974
Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy
1987 Science
ACTION OF THE NEUROTOXIN KAINIC ACID ON HIGH AFFINITY UPTAKE OF l ‐GLUTAMIC ACID IN RAT BRAIN SLICES
1979
Generation of slow postsynaptic potentials without increases in ionic conductance.
1968
Neuronal Mechanisms of Habituation and Dishabituation of the Gill-Withdrawal Reflex in Aplysia
1970 StandoutScienceNobel
Further Studies on Synaptic Transmission in Insects
1971
SUBSURFACE CISTERNS AND THEIR RELATIONSHIP TO THE NEURONAL PLASMA MEMBRANE
1962
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography
1982
Single glutamate-activated channels in locust muscle
1979 Nature
Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography
1984
Glutamate and the pathophysiology of hypoxic–ischemic brain damage
1986 Standout
The GABAergic nervous system of Caenorhabditis elegans
1993 StandoutNatureNobel
Synaptic Activation of an Electrogenic Sodium Pump
1969 StandoutScienceNobel
Crystal structure of leucine-enkephalin
1983 StandoutNatureNobel
Opiate receptor subclasses differ in their conformational requirements
1982 Nature
Aspinous and sparsely-spinous stellate neurons in the visual cortex of rats contain glutamic acid decarboxylase
1978
Distribution of putative neurotransmitters in the neocortex
1979
Benzodiazepine receptors in rat brain
1977 StandoutNature
Excitatory Amino Acid Transmitters
1981 Standout
Brain Tryptophan Hydroxylation: Dependence on Arterial Oxygen Tension
1973 StandoutScienceNobel
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Mechanism of facilitation at the crayfish neuromuscular junction
1961
Agonists and antagonists for excitatory amino acid receptors
1987
Tryptamine Receptors in the Central Nervous System: Effects of Anæsthetics
1963 StandoutNatureNobel
Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. III. Evidence for mediation of norepinephrine effects by cyclic 3′, 5′-adenosine monophosphate
1971
The Mating of a Fly
1994 StandoutScienceNobel
Protein synthesis and memory: A review.
1984
Genes required for GABA function in Caenorhabditis elegans
1993 StandoutNatureNobel
Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA
1983 Nature
The physiology of excitatory amino acids in the vertebrate central nervous system
1987 Standout
In vitro release and electrophysiological effects in situ of homocysteic acid, an endogenous N-methyl-(D)-aspartic acid agonist, in the mammalian striatum
1986
Transport and Metabolism of Glutamate and Gaba in Neurons and Glial Cells
1981
Interaction of Benzodiazepines with Central Nervous Glycine Receptors: Possible Mechanism of Action
1974
Uptake of a novel anticonvulsant compound, 2-amino-7-phosphono-[4,5-3H]Heptanoic acid, into mouse brain
1983
Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus
1983
Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones
1982 StandoutNatureNobel
Neuronal Correlates of Habituation and Dishabituation of the Gill-Withdrawal Reflex in Aplysia
1970 StandoutScienceNobel
Acquisition and Retention of Long-Term Habituation in Aplysia : Correlation of Behavioral and Cellular Processes
1973 StandoutScienceNobel
The action of Baclofen on neurons of the substantia nigra and of the ventral tegmental area
1977
(–)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor
1980 Nature
Synthesis of Heterocycles from Alkyl 3-(Dimethylamino)propenoates and Related Enaminones
2004 Standout
Ontogeny of adenosine 3?,5?-monophosphate metabolism in guinea pig cerebral cortex
1987
Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin
1987 StandoutScience
Quinolinic acid and other kynurenines in the central nervous system
1985
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Works of D.R. Curtis being referenced
Synthesis and Structure-Activity Studies on Excitatory Amino Acids Structurally Related to Ibotenic Acid
1985
Excitatory amino acid agonists. Enzymic resolution, x-ray structure, and enantioselective activities of (R)- and (S)-bromohomoibotenic acid
1989
THE PHARMACOLOGY OF AMINO ACIDS RELATED TO GAMMA-AMINOBUTYRIC ACID
1965
Bicuculline Methochloride as a GABA Antagonist
1972
Excitation of mammalian central neurones by acidic amino acids
1972
Securinine alkaloids: A new class of GABA receptor antagonist
1985
A pharmacological study of the depression of spinal neurones by glycine and related amino acids
1968
The inactivation of extracellularly administered amino acids in the feline spinal cord
1970
Central actions of shikimin and tutin
1973
The chemical excitation of spinal neurones by certain acidic amino acids
1960
Action of 3-Hydroxytyramine and some Tryptamine Derivatives on Spinal Neurones
1962 Nature
BENZODIAZEPINES AND CENTRAL GLYCINE RECEPTORS
1976
The hyperpolarization of spinal motoneurones by glycine and related amino acids
1968
A Central Action of 5-Hydroxytryptamine and Noradrenaline
1961 Nature
THE PHARMACOLOGY OF CENTRAL AND PERIPHERAL INHIBITION
1963
Antagonism between bicuculline and GABA in the cat brain
1971
Chemical Excitation of Spinal Neurones
1959 Nature
Central actions of ibotenic acid and muscimol
1968
Bicuculline and thalamic inhibition
1972
Pharmacological studies on feline Betz cells
1966
Potentiation of L‐Glutamate and L‐Aspartate Excitation of Cat Spinal Neurones by the Stereoisomers of threo‐3‐Hydroxyaspartate
1980
THE EXCITATION AND DEPRESSION OF MAMMALIAN CORTICAL NEURONES BY AMINO ACIDS
1964
Phaclofen: a peripheral and central baclofen antagonist
1987
The electrical constants of the motoneurone membrane
1959
Divalent cations reduce depolarization of primary afferent terminations by GABA
1987
Antagonism of neuronal excitation by 1-hydroxy-3-aminopyrrolidone-2
1973
A new class of GABA agonist
1977 StandoutNature
Central effects of β-(p-chlorophenyl)-γ-aminobutyric acid
1974
The depression of spinal neurones by γ‐amino‐n‐butyric acid and β‐alanine
1959
Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat
1971
The Excitation of Thalamic Neurones by Acetylcholine
1964
Intracellular Recording from Cells in Clarke's Column.
1958
Ibotenic acid analogs. Synthesis and biological and in vitro activity of conformationally restricted agonists at central excitatory amino acid receptors
1984
Central Synaptic Transmission-Microelectrophoretic Studies
1969
Acidic amino acids with strong excitatory actions on mammalian neurones
1963
In vivo inactivation of quisqualate: studies in the cat spinal cord
1980
Pharmacological investigations upon inhibition of spinal motoneurones
1959
The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar cortices of the cat
1971
The in vivo inactivation of GABA and other inhibitory amino acids in the cat nervous system
1976
Central Effects of β-N-Oxalyl-α,β-diaminopropionic Acid and other Lathyrus Factors
1966 Nature
Synaptic action during and after repetitive stimulation
1960
ACTIONS OF AMINO‐ACIDS ON THE ISOLATED HEMISECTED SPINAL CORD OF THE TOAD
1961
Acetylcholine sensitivity of cerebellar neurones in the cat
1966
Cholinergic and non‐cholinergic transmission in the mammalian spinal cord
1961
The excitation and depression of spinal neurones by ibotenic acid.
1979
Nicotinic and Muscarinic Receptors of Renshaw Cells
1964 Nature
The differential sensitivity of spinal interneurones and Renshaw cells to kainate and N-methyl-D-aspartate
1974
GABA, Bicuculline and Central Inhibition
1970 Nature
New class of glutamate agonist structurally related to ibotenic acid
1980 Nature
Amino acid transmitters in the mammalian central nervous system
1974
The specificity of strychnine as a glycine antagonist in the mammalian spinal cord
1971
ACTIONS OF AMINO‐ACIDS ON THE ISOLATED HEMISECTED SPINAL CORD OF THE TOAD
1997
THE EXCITATION AND DEPRESSION OF SPINAL NEURONES BY STRUCTURALLY RELATED AMINO ACIDS
1960
THE EXCITATION OF SPINAL NEURONES BY THE IONOPHORETIC APPLICATION OF AGENTS WHICH CHELATE CALCIUM
1960
Antagonists of synaptic and amino acid excitation of neurones in the cat spinal cord
1983
GABA and hippocampal inhibition
1970
Spinal interneurone excitation by conformationally restricted analogues of L-glutamic acid
1974 Nature
Selective antagonism by D-α-aminoadipate of amino acid and synaptic excitation of cat spinal neurons
1978