Citation Impact
Citing Papers
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus
2006 StandoutNobel
Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ
2008 StandoutNobel
ATR Homolog Mec1 Promotes Fork Progression, Thus Averting Breaks in Replication Slow Zones
2002 Science
Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation.
2003
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Cell mechanics and the cytoskeleton
2010 StandoutNature
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
Microtubule dynamics: taking aim at a moving target
1995
Stabilization of the cyclin‐dependent kinase 5 activator, p35, by paclitaxel decreases β‐amyloid toxicity in cortical neurons
2003
Characterization of the Taxol Binding Site on the Microtubule
1995
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
2007
Kinetic Stabilization of Microtubule Dynamics at Steady State in Vitro by Substoichiometric Concentrations of Tubulin-Colchicine Complex
1995
(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest
1996
DNA in a material world
2003 StandoutNature
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase
1995 StandoutNobel
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
The role of β-tubulin isotypes in resistance to antimitotic drugs
2001
Cell-cycle checkpoints and cancer
2004 StandoutNature
Molecular mechanisms of drug resistance
2005
HDAC6 is a microtubule-associated deacetylase
2002 StandoutNature
How Do Microtubule-Targeted Drugs Work? An Overview
2007
Genetic instabilities in human cancers
1998 StandoutNature
Paclitaxel (Taxol)
1995 Standout
Regional regulation of microtubule dynamics in polarized, motile cells
1999
Mechanisms of Taxol resistance related to microtubules
2003
Interrelationships of endoplasmic reticulum, mitochondria, intermediate filaments, and microtubules—a quadruple fluorescence labeling study
1992
When Checkpoints Fail
1997 StandoutNobel
Anticancer therapy with novel tubulin-interacting drugs
2001
Microtubules and actin filaments: dynamic targets for cancer chemotherapy
1998
The spindle assembly checkpoint
1996
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
Characterization of a Taxol‐resistant Human Small‐cell Lung Cancer Cell Line
1994
Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.
1997
Vincristine revisited
1999
Identification of a Protein That Interacts with Tubulin Dimers and Increases the Catastrophe Rate of Microtubules
1996
A Long Twentieth Century of the Cell Cycle and Beyond
2000 StandoutNobel
Binding of Activated Cyclosome to p13
1997 StandoutNobel
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
1994
The 1p-Encoded Protein Stathmin and Resistance of Malignant Gliomas to Nitrosoureas
2007
Isolation, Characterization, and Partial Purification of a Novel Ubiquitin-Protein Ligase, E3
1996 StandoutNobel
Structural basis for the regulation of tubulin by vinblastine
2005 Nature
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
The Cyclin-Ubiquitin Ligase Activity of Cyclosome/APC Is Jointly Activated by Protein Kinases Cdk1-Cyclin B and Plk
2002 StandoutNobel
Control of apoptosis and mitotic spindle checkpoint by survivin
1998 StandoutNature
Stimulation of Flap Endonuclease-1 by the Bloom's Syndrome Protein
2004
Overcoming Multidrug Resistance in Taxane Chemotherapy
2002
Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats
2010
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
The microenvironment of the tumour–host interface
2001 StandoutNature
Malignant Gliomas in Adults
2008 Standout
Cell cycle checkpoints
1994
Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA
2010
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition
1995
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Molecular Basis for Class V β-Tubulin Effects on Microtubule Assembly and Paclitaxel Resistance
2009
Structure of the αβ tubulin dimer by electron crystallography
1998 StandoutNature
Alzheimer's Disease
2010 Standout
NFBD1/KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways
2003
Microtubules as a target for anticancer drugs
2004 Standout
Membrane curvature and mechanisms of dynamic cell membrane remodelling
2005 StandoutNature
Algorithmic Self-Assembly of DNA: Theoretical Motivations and 2D Assembly Experiments
2000
The Hallmarks of Aging
2013 Standout
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Is class III β-tubulin a predictive factor in patients receiving tubulin-binding agents?
2008
In vitro synergy of paclitaxel (Taxol) and vinorelbine (navelbine) against human melanoma cell lines
1997
Effects of Nanomolar taxol on crane-fly spermatocyte spindles indicate that acetylation of kinetochore microtubules can be used as a marker of poleward tubulin flux
1997
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
Paclitaxel-resistant Human Ovarian Cancer Cells Have Mutant β-Tubulins That Exhibit Impaired Paclitaxel-driven Polymerization
1997
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
2010 Nature
Reaching out for signals
2005
The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells
1997
Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochore-microtubule attachment and in centrosomes
1993
Tubulin depolymerization may be an ancient biological motor
2010
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase
2008
Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines.
2000
Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
1995
Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs.
2002
Micromechanical Studies of Mitotic Chromosomes
2003
Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells.
1996
The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle
1995
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Stathmin 1: a novel therapeutic target for anticancer activity
2008
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: A possible mechanistic basis for its antitumor action
1997
Plk Phosphorylation Regulates the Microtubule-Stabilizing Protein TCTP
2002
Mechanisms of Action of and Resistance to Antitubulin Agents: Microtubule Dynamics, Drug Transport, and Cell Death
1999
A phase I trial of carboxyamido-triazole and paclitaxel for relapsed solid tumors: potential efficacy of the combination and demonstration of pharmacokinetic interaction.
2001
Identification of a Human Mitotic Checkpoint Gene: hsMAD2
1996 Science
Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization.
2004
Rapid dynamics of the microtubule binding of ensconsin in vivo
2001
E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins.
1996 StandoutNobel
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Analysis of Tubulin Isotypes and Mutations from Taxol-Resistant Cells by Combined Isoelectrofocusing and Mass Spectrometry
2003
Electrostatics of nanosystems: Application to microtubules and the ribosome
2001 Standout
Polymerizing Microtubules Activate Site-directed F-Actin Assembly in Nerve Growth Cones
1999
Combretastatin A-4 resistance in H460 human lung carcinoma demonstrates distinctive alterations in beta-tubulin isotype expression.
2006
The Seco-Taxane IDN5390 Is Able to Target Class III β-Tubulin and to Overcome Paclitaxel Resistance
2005
Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome
2005
Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption
1998
Conservation of the class I beta-tubulin gene in human populations and lack of mutations in lung cancers and paclitaxel-resistant ovarian cancers.
2002
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle.
1994
Force Generation by Microtubule Assembly/Disassembly in Mitosis and Related Movements
1995
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Cell Cycle-Dependent Changes in Microtubule Dynamics in Living Cells Expressing Green Fluorescent Protein-α Tubulin
2001
MICROTUBULE POLYMERIZATION DYNAMICS
1997 Standout
Suppression of centromere dynamics by Taxol in living osteosarcoma cells.
2003
Emerging Targets in Photopharmacology
2016 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.
1995
Additivity of dilantin and vinblastine inhibitory effects on microtubule assembly.
1999
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics
2001
The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.
1996
The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work.
1996
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Compact Biocompatible Quantum Dots Functionalized for Cellular Imaging
2008 StandoutNobel
Membrane Expansion Increases Endocytosis Rate during Mitosis
1999
Visualizing Chromatin Dynamics in Interphase Nuclei
2002 Science
Taxol Suppresses Dynamics of Individual Microtubules in Living Human Tumor Cells
1999
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics.
2003
Dynamics of Axonal Microtubules Regulate the Topology of New Membrane Insertion into the Growing Neurites
1998
Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase.
1995 StandoutNobel
Works of Douglas Thrower being referenced
Quantitation of cellular tubulin in microtubules and tubulin pools by a competitive ELISA
1991
Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability
2003
Stathmin Strongly Increases the Minus End Catastrophe Frequency and Induces Rapid Treadmilling of Bovine Brain Microtubules at Steady State in Vitro
2005
Vinblastine suppresses dynamics of individual microtubules in living interphase cells.
1995
Mechanism of inhibition of cell proliferation by Vinca alkaloids.
1991
β-Tubulin C354 Mutations that Severely Decrease Microtubule Dynamics Do Not Prevent Nuclear Migration in Yeast
2002
Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles : Implications for the role of microtubule dynamics in mitosis
1992
Dicentric Chromosome Stretching during Anaphase Reveals Roles of Sir2/Ku in Chromatin Compaction in Budding Yeast
2001
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.
1993
Probing the Saccharomyces cerevisiae centromeric DNA ( CEN DNA)–binding factor 3 (CBF3) kinetochore complex by using atomic force microscopy
1999