Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Runx1 Determines Nociceptive Sensory Neuron Phenotype and Is Required for Thermal and Neuropathic Pain
2006
Keeping in touch: sensory neurone regeneration in the CNS
2000
A Role for Runx Transcription Factor Signaling in Dorsal Root Ganglion Sensory Neuron Diversification
2006
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Formation of a full complement of cranial proprioceptors requires multiple neurotrophins
2000
Injured primary sensory neurons switch phenotype for brain-derived neurotrophic factor in the rat
1999
GFRα3, a Component of the Artemin Receptor, Is Required for Migration and Survival of the Superior Cervical Ganglion
1999
Sodium channel expression in NGF-overexpressing transgenic mice
1999
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Sense and specificity: a molecular identity for nociceptors
1999 StandoutNobel
Apoptosis in the nervous system
2000 StandoutNature
P2X receptors in the rat uterine cervix, lumbosacral dorsal root ganglia, and spinal cord during pregnancy
2005
Emergence of Functional Sensory Subtypes as Defined by Transient Receptor Potential Channel Expression
2007
Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse
2005
Differential development of TRPV1-expressing sensory nerves in peripheral organs
2005
Novel class of pain drugs based on antagonism of NGF
2005
Adenosine triphosphate-evoked currents in cultured dorsal root ganglion neurons obtained from rat embryos: desensitization kinetics and modulation of glutamate release
2000
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
NEUROGENIN1 and NEUROGENIN2 control two distinct waves of neurogenesis in developing dorsal root ganglia
1999
Tackling Pain at the Source: New Ideas about Nociceptors
1998
The Role of POU Domain Proteins in the Regulation of Mammalian Pituitary and Nervous System Development
1999
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Peripheral NT3 Signaling Is Required for ETS Protein Expression and Central Patterning of Proprioceptive Sensory Afferents
2003
Glial Cell Line-Derived Neurotrophic Factor Expression in Skin Alters the Mechanical Sensitivity of Cutaneous Nociceptors
2006
Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin
1999
P2Y2 receptors activate neuroprotective mechanisms in astrocytic cells
2004
Formation of lamina-specific synaptic connections
1999
Purinergic P2 receptors as targets for novel analgesics
2005
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Proprioceptive afferents survive in the masseter muscle of trkC knockout mice
1999
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
2006
Central changes in primary afferent fibers following peripheral nerve lesions
1997
Itching for Insight
2009 StandoutNobel
BAX Is Required for Neuronal Death after Trophic Factor Deprivation and during Development
1996
Development of Sensory Neurons in the Absence of NGF/TrkA Signaling In Vivo
2000
The Expression of P2X3Purinoreceptors in Sensory Neurons: Effects of Axotomy and Glial-Derived Neurotrophic Factor
1998
Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with aδ/c‐fibers and colocalization with trk receptors
2005
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
2004
Promoting directional axon growth from neural progenitors grafted into the injured spinal cord
2009
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
TRPV2, a capsaicin receptor homologue, is expressed predominantly in the neurotrophin-3-dependent subpopulation of primary sensory neurons
2004
Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons
2011 StandoutNobel
Rho GTPases in cell biology
2002 StandoutNature
The survival of vagal and glossopharyngeal sensory neurons is dependent upon dystonin
2005
Defining brain wiring patterns and mechanisms through gene trapping in mice
2001 Nature
The Paired Homeodomain Protein DRG11 Is Required for the Projection of Cutaneous Sensory Afferent Fibers to the Dorsal Spinal Cord
2001
Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons
1999
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
1999
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Corneal innervation and sensitivity to noxious stimuli in trkA knockout mice
1998
Analysis of Cutaneous Sensory Neurons in Transgenic Mice Lacking the Low Affinity Neurotrophin Receptor p75
1997
Cytotoxic targeting of isolectin IB4-binding sensory neurons
2001
The P2Y agonist UTP activates cutaneous afferent fibers
2004
The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
2005
Artemin Overexpression in Skin Enhances Expression of TRPV1 and TRPA1 in Cutaneous Sensory Neurons and Leads to Behavioral Sensitivity to Heat and Cold
2006
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Nucleotide signaling in nervous system development
2006
Muscle-Specific Cell Ablation Conditional upon Cre-Mediated DNA Recombination in Transgenic Mice Leads to Massive Spinal and Cranial Motoneuron Loss
1998
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Chondroitinase ABC promotes functional recovery after spinal cord injury
2002 StandoutNature
Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation
2005
Regulation of neurotrophin‐induced axonal responses via Rho GTPases
2001
Gene Targeting Reveals a Critical Role for Neurturin in the Development and Maintenance of Enteric, Sensory, and Parasympathetic Neurons
1999
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
1999
ATP Augments Peptide Release from Rat Sensory Neurons in Culture through Activation of P2Y Receptors
2003
Protein kinase C mediates up‐regulation of tetrodotoxin‐resistant, persistent Na+ current in rat and mouse sensory neurones
2005
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Semaphorin III is needed for normal patterning and growth of nerves, bones and heart
1996 Nature
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
P2X3 is expressed by DRG neurons that terminate in inner lamina II
1998
Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors
2016
Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
2004 StandoutNobel
Immune and inflammatory mechanisms in neuropathic pain
2006
Comparative study of the distribution of the α‐subunits of voltage‐gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
2008
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction
2006
Neuronal Cell Death
1998
A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons
2001
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
2004
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Nociceptors—Noxious Stimulus Detectors
2007
Direct Excitation of Hypocretin/Orexin Cells by Extracellular ATP at P2X Receptors
2005
Axotomy results in major changes in BDNF expression by dorsal root ganglion cells: BDNF expression in large trkB and trkC cells, in pericellular baskets, and in projections to deep dorsal horn and dorsal column nuclei
1999
Differential Dependency of Cutaneous Mechanoreceptors on Neurotrophins, trk Receptors, and P75 LNGFR
1997
The changing sensitivity in the life of the nociceptor
1999
Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord
2006
Neurotrophin action on sensory neurons in adults: an extension of the neurotrophic hypothesis
1999
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
1999
Purinergic receptor modulation of BV-2 microglial cell activity: Potential involvement of p38 MAP kinase and CREB
2005
Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
1998
A role for BDNF in mechanosensation
1998
Effects of extracellular atp on axonal transport in cultured mouse dorsal root ganglion neurons
2003
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Nerve Growth Factor Treatment Increases Brain-Derived Neurotrophic Factor Selectively in TrkA-Expressing Dorsal Root Ganglion Cells and in Their Central Terminations within the Spinal Cord
1997
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
P2Y2receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation
2005
Dynamic Expression of Neurotrophin Receptors during Sensory Neuron Genesis and Differentiation
2000
Localization of P2X and P2Y Receptors in Dorsal Root Ganglia of the Cat
2005
Neurotrophin 4 Is Required for the Survival of a Subclass of Hair Follicle Receptors
1998
Development, Maturation, and Transdifferentiation of Cardiac Sympathetic Nerves
2012
Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development
2003
Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor
2012
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice
2000
Brain-derived neurotrophic factor is an endogenous modulator of nociceptive responses in the spinal cord
1999
p75 Is Important for Axon Growth and Schwann Cell Migration during Development
2000
Differential dependency of unmyelinated and Aδ epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR
1998
Glial Cell Line-Derived Neurotrophic Factor is a Survival Factor for Isolectin B4-Positive, but not Vanilloid Receptor 1-Positive, Neurons in the Mouse
2002
The use of synthetic peptides for defining the specificity of typrosine protein kinases
1984 StandoutNobel
Effects of BDNF and NT-3 on Development of Ia/Motoneuron Functional Connectivity in Neonatal Rats
1999
Synaptic Activity and the Construction of Cortical Circuits
1996 StandoutScience
Neurotrophins and hyperalgesia
1999
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation
2004
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
GFRα1 Is Required for Development of Distinct Subpopulations of Motoneuron
2000
Neural Science
2000 StandoutNobel
Small GTPases Rac and Rho in the Maintenance of Dendritic Spines and Branches in Hippocampal Pyramidal Neurons
2000
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Neuronal and non-neuronal collapsin-1 binding sites in developing chick are distinct from other semaphorin binding sites.
1997
Distinct Mechanosensitive Properties of Capsaicin-Sensitive and -Insensitive Sensory Neurons
2002
BDNF but not NT-4 is required for normal flexion reflex plasticity and function
2001
Erythropoietin both protects from and reverses experimental diabetic neuropathy
2004
TRPA1 mediates formalin-induced pain
2007 StandoutNobel
A sensory neuron-specific, proton-gated ion channel
1998
Physiology of the Neurotrophins
1996 Standout
Glial Cell Line-Derived Neurotrophic Factor and Developing Mammalian Motoneurons: Regulation of Programmed Cell Death Among Motoneuron Subtypes
2000
Inflammatory mediators and modulators of pain
2006
Brain-Derived Neurotrophic Factor Modulates Nociceptive Sensory Inputs and NMDA-Evoked Responses in the Rat Spinal Cord
1999
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Differential Expression of the mRNA for the Vanilloid Receptor Subtype 1 in Cells of the Adult Rat Dorsal Root and Nodose Ganglia and Its Downregulation by Axotomy
1999
Neurotrophins: Peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity
1999
Activity-Dependent Release of Endogenous Brain-Derived Neurotrophic Factor from Primary Sensory Neurons Detected by ELISAIn Situ
2000
The Low-Affinity Neurotrophin Receptor p75 Regulates the Function But Not the Selective Survival of Specific Subpopulations of Sensory Neurons
1997
The Molecular Biology of Axon Guidance
1996 StandoutScience
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Isolectin B4-Positive and -Negative Nociceptors Are Functionally Distinct
1999
Neuronal Plasticity: Increasing the Gain in Pain
2000 StandoutScience
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
A rapid and dynamic regulation of GDNF-family ligands and receptors correlate with the developmental dependency of cutaneous sensory innervation
1999
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.
1998
POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression
1999
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase.
1985 StandoutNobel
Works of Douglas E. Wright being referenced
Introduction of a Neurotrophin-3 Transgene into Muscle Selectively Rescues Proprioceptive Neurons in Mice Lacking Endogenous Neurotrophin-3
1997
Restorative effects of neurotrophin treatment on diabetes-induced cutaneous axon loss in mice
2003
Neurotrophic modulation of myelinated cutaneous innervation and mechanical sensory loss in diabetic mice
2006
Focal expression of glial cell line-derived neurotrophic factor in developing mouse limb bud
1996
Glial cell line‐derived neurotrophic factor‐responsive and neurotrophin‐3‐responsive neurons require the cytoskeletal linker protein dystonin for postnatal survival
2001
Nerve Growth Factor Regulates the Expression of Brain-Derived Neurotrophic Factor mRNA in the Peripheral Nervous System
1996
Diabetic neuropathy
2019
IB4-Binding DRG Neurons Switch from NGF to GDNF Dependence in Early Postnatal Life
1997
ATP and UTP excite sensory neurons and induce CREB phosphorylation through the metabotropic receptor, P2Y2
2002
The guidance molecule Semaphorin III is expressed in regions of spinal cord and periphery avoided by growing sensory axons
1995
Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia
1995
Cloning and Expression of a Novel Murine Semaphorin with Structural Similarity to Insect Semaphorin I
1997
Fluorometric assay for adenosine 3',5'-cyclic monophosphate-dependent protein kinase and phosphoprotein phosphatase activities.
1981
Neurotrophins Cause a New Sensation
1996
Abnormal Muscle Spindle Innervation and Large-Fiber Neuropathy in Diabetic Mice
2008
Modulation of diet‐induced mechanical allodynia by metabolic parameters and inflammation
2016