Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
2004 Standout
Accelerated telomere shortening in response to life stress
2004 StandoutNobel
Plasmacytoid Dendritic Cell Dynamics and Alpha Interferon Production during Simian Immunodeficiency Virus Infection with a Nonpathogenic Outcome
2008 StandoutNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
2003
Progressive CD4+ central–memory T cell decline results in CD4+ effector–memory insufficiency and overt disease in chronic SIV infection
2007
The CCR5 and CXCR4 Coreceptors—Central to Understanding the Transmission and Pathogenesis of Human Immunodeficiency Virus Type 1 Infection
2004
The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response
2009 StandoutNobel
Can eradication of helminthic infections change the face of AIDS and tuberculosis?
1999
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection
2006
Pre-seroconversion immune status predicts the rate of CD4 T cell decline following HIV infection
2004
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Concomitant regulation of T-cell activation and homeostasis
2004
CD27 is required for generation and long-term maintenance of T cell immunity
2000
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
2003 Standout
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level
2006
Human CD8+ T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells
2001
Pathogenesis of HIV infection: what the virus spares is as important as what it destroys
2006
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Impact of Antiretroviral Therapy and Changes in Virus Load on Human Immunodeficiency Virus (HIV)–Specific T Cell Responses in Primary HIV Infection
2003
Complementary Role of HCV and HIV in T-Cell Activation and Exhaustion in HIV/HCV Coinfection
2013
Genetic Analyses of Integrin Signaling
2010
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
2006 Standout
Lack of Epstein-Barr virus- and HIV-specific CD27− CD8+ T cells is associated with progression to viral disease in HIV-infection
2002
Skewed maturation of memory HIV-specific CD8 T lymphocytes
2001 Nature
Analysis of the Frequencies and of the Memory T Cell Phenotypes of Human CD8+T Cells Specific for Influenza A Viruses
2003
CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
2000
Incomplete CD4 T Cell Recovery in HIV-1 Infection After 12 Months of Highly Active Antiretroviral Therapy Is Associated With Ongoing Increased CD4 T Cell Activation and Turnover
2003
Discordant Increases in CD4+T Cells in Human Immunodeficiency Virus–Infected Patients Experiencing Virologic Treatment Failure: Role of Changes in Thymic Output and T Cell Death
2001
Immune Restoration With Antiretroviral Therapies
2000
Lessons from the study of T-cell differentiation in persistent human virus infection
2004
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells
2004
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Distinct expression profiles of TGF-β1 signaling mediators in pathogenic SIVmac and non-pathogenic SIVagm infections
2006 StandoutNobel
α-Latrotoxin Receptor CIRL/Latrophilin 1 (CL1) Defines an Unusual Family of Ubiquitous G-protein-linked Receptors
1998 StandoutNobel
Genetic analysis of integrin function in man: LAD-1 and other syndromes
2000
Principles of adoptive T cell cancer therapy
2007
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy
2003
Leukocyte adhesion deficiency syndromes: adhesion and tethering defects involving β 2 integrins and selectin ligands
2002
Human memory CCR4+CD8+ T cell subset has the ability to produce multiple cytokines
2009
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
1999 StandoutNature
Multiparameter evaluation of human thymic function: interpretations and caveats
2005
Post-translational Proteolytic Processing of the Calcium-independent Receptor of α-Latrotoxin (CIRL), a Natural Chimera of the Cell Adhesion Protein and the G Protein-coupled Receptor
2002
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection
2004
Poor CD4 T cell restoration after suppression of HIV-1 replication may reflect lower thymic function
2001
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
1998
Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer
2017 StandoutNobel
Seventeen-colour flow cytometry: unravelling the immune system
2004
De novo T-cell generation in patients at different ages and stages of HIV-1 disease
2004
CD69, HLA-DR and the IL-2R Identify Persistently Activated T Cells in Psoriasis Vulgaris Lesional Skin: Blood and Skin Comparisons by Flow Cytometry
2000
Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin
2004
Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation
2005
Points of control in inflammation
2002 StandoutNature
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III
2007
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
Lineage relationship and protective immunity of memory CD8 T cell subsets
2003 Standout
Integrins
2002 Standout
Nonpathogenic SIV Infection of Sooty Mangabeys Is Characterized by Limited Bystander Immunopathology Despite Chronic High-Level Viremia
2003
Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines
2008
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors
2002
Phenotype and function of human T lymphocyte subsets: Consensus and issues
2008
HIV Infection Rapidly Induces and Maintains a Substantial Suppression of Thymocyte Proliferation
2004
Molecular regulation of effector and memory T cell differentiation
2014
Human CD8+ T-cell differentiation in response to viruses
2003
Identification of Naive or Antigen-Experienced Human CD8+ T Cells by Expression of Costimulation and Chemokine Receptors: Analysis of the Human Cytomegalovirus-Specific CD8+ T Cell Response
2002
Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells
2000
Deregulation of the expression of the fractalkine/fractalkine receptor complex in HIV-1–infected patients
2001
CD8+ T Cells Specific for EBV, Cytomegalovirus, and Influenza Virus Are Activated during Primary HIV Infection
2004
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor
2000
Interleukin-7 in Plasma Correlates with CD4 T-Cell Depletion and May Be Associated with Emergence of Syncytium-Inducing Variants in Human Immunodeficiency Virus Type 1-Positive Individuals
2001
Insufficient Production and Tissue Delivery of CD4+Memory T Cells in Rapidly Progressive Simian Immunodeficiency Virus Infection
2004
Long-term T-cell reconstitution after hematopoietic stem-cell transplantation in primary T-cell–immunodeficient patients is associated with myeloid chimerism and possibly the primary disease phenotype
2007
Epitope-specific Evolution of Human CD8+ T Cell Responses from Primary to Persistent Phases of Epstein-Barr Virus Infection
2002
T Cell Homeostasis
2001
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
2002 StandoutScience
High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals
1999
Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation
2006
Gamma Interferon-Mediated Inflammation Is Associated with Lack of Protection from Intravaginal Simian Immunodeficiency Virus SIVmac239 Challenge in Simian-Human Immunodeficiency Virus 89.6-Immunized Rhesus Macaques
2003
Proliferation Requirements of Cytomegalovirus-Specific, Effector-Type Human CD8+ T Cells
2002
Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease
2000 StandoutScience
Memory CD8 T-Cell Differentiation during Viral Infection
2004
HIV Antigens Can Induce TGF-β1-Producing Immunoregulatory CD8+ T Cells
2002
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions
2003
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
Immortalization of Human CD8+ T Cell Clones by Ectopic Expression of Telomerase Reverse Transcriptase
2000
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
CCR7 Expression and Memory T Cell Diversity in Humans
2001
Functional Properties and Lineage Relationship of CD8+ T Cell Subsets Identified by Expression of IL-7 Receptor α and CD62L
2005
Naive T-Cell Depletion Related to Infection by X4 Human Immunodeficiency Virus Type 1 in Poor Immunological Responders to Highly Active Antiretroviral Therapy
2006 StandoutNobel
CD127 expression and regulation are altered in the memory CD8 T cells of HIV-infected patients − reversal by highly active anti-retroviral therapy (HAART)
2006
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
2003
Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood
1999
The paradox of Simian immunodeficiency virus infection in Sooty Mangabeys: active viral replication without disease progression
2004
EBV-Specific CD8+ T Cell Memory: Relationships Between Epitope Specificity, Cell Phenotype, and Immediate Effector Function
2001
Differentiation of Human CD8+ T Cells from a Memory to Memory/Effector Phenotype
2002
T Cell Dynamics in HIV-1 Infection
2003
Arrested Differentiation, the Self-Renewing Memory Lymphocyte, and Vaccination
2001 Science
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance
2004 Standout
Differentiating between Memory and Effector Cd8 T Cells by Altered Expression of Cell Surface O-Glycans
2000
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
CXCR4-Tropic HIV-1 Envelope Glycoprotein Functions as a Viral Chemokine in Unstimulated Primary CD4+ T Lymphocytes
2004
Dynamics of the Cytotoxic T Cell Response to a Model of Acute Viral Infection
2015
Maintenance of Large Numbers of Virus-Specific CD8+ T Cells in HIV-Infected Progressors and Long-Term Nonprogressors
2000
Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies
1999
Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo
1998
Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy
2005
Evidence for Increased T Cell Turnover and Decreased Thymic Output in HIV Infection
2001
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function
2000
The role of the immune response during SIVagm infection of the african green monkey natural host
2004
Cytopathic Effects of Non-Syncytium-Inducing and Syncytium-Inducing Human Immunodeficiency Virus Type 1 Variants on Different CD4+-T-Cell Subsets Are Determined Only by Coreceptor Expression
2001
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Dynamics of T Cells and TCR Excision Circles Differ After Treatment of Acute and Chronic HIV Infection
2002
Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+ T Cells Closely Correlates with CD56 Surface Expression
2000
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
Immunological changes in simian immunodeficiency virus (SIVagm)-infected African green monkeys (AGM): expanded cytotoxic T lymphocyte, natural killer and B cell subsets in the natural host of SIVagm
2002
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
From hematopoiesis to neuropoiesis: Evidence of overlapping genetic programs
2001
Persistence of Memory CD8 T Cells in MHC Class I-Deficient Mice
1999 Science
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
DNA Methylation and Chromatin Structure Regulate T Cell Perforin Gene Expression
2003
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Positive Regulation of CXCR4 Expression and Signaling by Interleukin-7 in CD4+Mature Thymocytes Correlates with Their Capacity To Favor Human Immunodeficiency X4 Virus Replication
2003 StandoutNobel
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection
2002
Impact of bone marrow hematopoiesis failure on T-cell generation during pathogenic simian immunodeficiency virus infection in macaques
2004
In vivoHIV-1 infection of CD45RA+CD4+T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4+T cell decline
2000
Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes
1999 Science
Identification of Dynamically Distinct Subpopulations of T Lymphocytes That Are Differentially Affected by HIV
2001
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses
2007
IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro
2003
CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load
2002
Dual-Color Bioluminescent Sensor Proteins for Therapeutic Drug Monitoring of Antitumor Antibodies
2018
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Human immunodeficiency virus–driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
2004
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
2004
Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity.
2002
Works of Dörte Hamann being referenced
Evidence that human CD8+CD45RA+CD27– cells are induced by antigen and evolve through extensive rounds of division
1999
Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy
1999
Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation
2003
Immune Reconstitution after 2 Years of Successful Potent Antiretroviral Therapy in Previously Untreated Human Immunodeficiency Virus Type 1–Infected Adults
1999
The Dominant Source of CD4+ and CD8+ T-Cell Activation in HIV Infection Is Antigenic Stimulation
2000
Faces and phases of human CD8+ T-cell development
1999
Leukocyte adhesion deficiency type 1 (LAD-1)/variant. A novel immunodeficiency syndrome characterized by dysfunctional beta2 integrins.
1997
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
2003
T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation
2001
T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock
2000
Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue
2002
Restored humoral immune response to influenza vaccination in HIV-infected adults treated with highly active antiretroviral therapy
1998
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
2000
Therapeutic drug monitoring of infliximab: performance evaluation of three commercial ELISA kits
2015
Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain
1995
Longitudinal Phenotypic Analysis of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes: Correlation with Disease Progression
1999
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)
2000
Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T- cell subsets characterized by coexpression of CD45RA and CD45RO isoforms
1996
Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells
1997
Reduced naive and increased activated CD4 and CD8 cells in healthy adult Ethiopians compared with their Dutch counterparts
1999
T-cell receptor excision circle and T-cell dynamics after allogeneic stem cell transplantation are related to clinical events
2002
Changes in the Composition of Circulating CD8+T Cell Subsets during Acute Epstein‐Barr and Human Immunodeficiency Virus Infections in Humans
2000