Standout Papers
Citation Impact
Citing Papers
Contingent gene regulatory networks and B cell fate specification
2005
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome
2016
Nodal and splenic marginal zone B cell lymphomas
2005
CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis
2004
Chromosomal Aberration Patterns Differ in Subtypes of Primary Cutaneous B Cell Lymphomas
2004
Autophagy genes as tumor suppressors
2009
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Anaplastic lymphoma kinase proteins in growth control and cancer
2004
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer
2017 Standout
Influence of new molecular prognostic markers in patients with karyotypically normal acute myeloid leukemia: recent advances
2007
The Human Transcription Factors
2018 Standout
Activation-Induced Cytidine Deaminase Induces Reproducible DNA Breaks at Many Non-Ig Loci in Activated B Cells
2011
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
WHO-EORTC classification for cutaneous lymphomas
2005 Standout
Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor
2010 Standout
Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation
2005
An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries
2017
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
2007
Epigenetics in Cancer
2008 Standout
Mycosis Fungoides
2000
Lung cancer: current therapies and new targeted treatments
2016 Standout
The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation
2015 StandoutNobel
A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations
2003
Cell-free nucleic acids as biomarkers in cancer patients
2011 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
Molecular Dissection of the [epsilon] Subunit of the Chloroplast ATP Synthase of Spinach
1995
Autophagy in Human Health and Disease
2013 Standout
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
2013 Standout
Alpharetroviral Vector-mediated Gene Therapy for X-CGD: Functional Correction and Lack of Aberrant Splicing
2012
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma
2003
Sickle-cell disease
2010 Standout
RNA-Based Tools for Nuclear Reprogramming and Lineage-Conversion: Towards Clinical Applications
2013
Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells
2007
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
2017 Nature
The Transcriptional Regulation of B Cell Lineage Commitment
2007
Clinical implications of ELA2‐, HAX1‐, and G‐CSF‐receptor (CSF3R) mutations in severe congenital neutropenia
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Drug resistance in cancer – searching for mechanisms, markers and therapeutic agents
2007
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
Reading, writing and erasing mRNA methylation
2019 Standout
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
2004 Standout
Increasing genomic and epigenomic complexity in the clonal evolution from in situ to manifest t(14;18)-positive follicular lymphoma
2013
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Involvement of the Histone Deacetylase SIRT1 in Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF)-interacting Protein 2-mediated Transcriptional Repression
2003
Modes of resistance to anti-angiogenic therapy
2008 Standout
Refined sgRNA efficacy prediction improves large- and small-scale CRISPR–Cas9 applications
2017 StandoutNobel
Neutrophil recruitment and function in health and inflammation
2013 Standout
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
2011 Standout
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
STATs: transcriptional control and biological impact
2002 Standout
Overexpression of the ETS-Related Gene, ERG, Predicts a Worse Outcome in Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study
2005
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma
2007 Standout
Therapeutic Targeting of Anaplastic Lymphoma Kinase in Lung Cancer: A Paradigm for Precision Cancer Medicine
2015
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
DNA polymorphisms at the BCL11A , HBS1L-MYB , and β- globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
2008
THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE
1997 StandoutNobel
Quantitative Methylation-Specific Polymerase Chain Reaction Gene Patterns in Urine Sediment Distinguish Prostate Cancer Patients From Control Subjects
2005
Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma
2002
Cell cycle deregulation in B-cell lymphomas
2003
Ongoing In Vivo Immunoglobulin Class Switch DNA Recombination in Chronic Lymphocytic Leukemia B Cells
2002
Prognostic Significance ofASXL1Mutations in Patients With Myelodysplastic Syndromes
2011
Advances in the biology and therapy of diffuse large B-cell lymphoma: moving toward a molecularly targeted approach
2005
High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
2006
Quantitative Analysis of Circulating Methylated DNA as a Biomarker for Hepatocellular Carcinoma
2008
Anaplastic lymphoma kinase: signalling in development and disease
2009
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Mechanisms of Renal Fibrosis
2017 Standout
KRAB zinc finger proteins
2017
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
A Comparative View on Human Somatic Cell Sources for iPSC Generation
2014
Works of Doris Steinemann being referenced
Identification of candidate tumor‐suppressor genes in 6q27 by combined deletion mapping and electronic expression profiling in lymphoid neoplasms
2003
Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11
2007
Chromosomal aberrations in congenital bone marrow failure disorders—an early indicator for leukemogenesis?
2007
Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells
2017
Over-production, renaturation and reconstitution of δ and ϵ subunits from chloroplast and cyanobacterial F1
1994
Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies
2001
Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia
2014
Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Murine Leukemia
2012
Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma
2003
BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib
2005
Quantitative microsatellite analysis to delineate the commonly deleted region 1p22.3 in mantle cell lymphomas
2006
The heteromeric transcription factor GABP activates the ITGAM/CD11b promoter and induces myeloid differentiation
2015
Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells
2012
The stem cell zinc finger 1 (SZF1)/ZNF589 protein has a human-specific evolutionary nucleotide DNA change and acts as a regulator of cell viability in the hematopoietic system
2015
Sustained Knockdown of a Disease-Causing Gene in Patient-Specific Induced Pluripotent Stem Cells Using Lentiviral Vector-Based Gene Therapy
2013
Complex variant translocation t(1;2) with TPM3-ALK fusion due to cryptic ALK gene rearrangement in anaplastic large-cell lymphoma.
1999
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies
2001
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis
2016
Gene-expression profiles and their association with drug resistance in adult acute myeloid leukemia.
2005