Standout Papers
Citation Impact
Citing Papers
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 Standout
Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases
2007
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
PDE4 cAMP-specific phosphodiesterases
2001
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
The RB and p53 pathways in cancer
2002 Standout
GSK3 takes centre stage more than 20 years after its discovery
2001
The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
2001 Standout
Rewiring of the Fruit Metabolome in Tomato Breeding
2018 Standout
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
2000
Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future
2012
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Anthocyanins Inhibit Nuclear Factor-κB Activation in Monocytes and Reduce Plasma Concentrations of Pro-Inflammatory Mediators in Healthy Adults , ,3
2007
Cyclin‐dependent kinase inhibitors for treating cancer
2001
Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines
2006
Indirubin and Indigo Are Potent Aryl Hydrocarbon Receptor Ligands Present in Human Urine
2001
Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest
2001
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins
2004
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Human Tdp1 Cleaves a Broad Spectrum of Substrates, Including Phosphoamide Linkages
2005
Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora
2005
Analysis and biological activities of anthocyanins
2003
The role of protein phosphorylation in human health and disease.
2001
Indoles — A promising scaffold for drug development
2016
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
The next generation of PDE4 inhibitors
2001
Intracellular Targets of Paullones
2002
A Review of the Effects and Mechanisms of Polyphenolics in Cancer
2006
Platinum nanozymes recover cellular ROS homeostasis in an oxidative stress-mediated disease model
2016
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
GSK3 inhibitors: development and therapeutic potential
2004
GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins
2003 Standout
Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Repairs DNA Damage Induced by Topoisomerases I and II and Base Alkylation in Vertebrate Cells
2012
Identification of an indigo precursor from leaves of Isatis tinctoria (Woad)
2001
Protein kinases — the major drug targets of the twenty-first century?
2002 Standout
Glycogen synthase kinase 3 (GSK‐3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
2002
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Indirubin and Meisoindigo in the Treatment of Chronic Myelogenous Leukemia in China
2002
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways
2008 Standout
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila
2003 Standout
Cyclin D-dependent kinases, INK4 inhibitors and cancer
2002
Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine spongeconstituent
2000
Cyanidins: metabolism and biological properties
2004
Cytochrome p450 enzymes in the generation of commercial products
2002
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
To cycle or not to cycle: a critical decision in cancer
2001
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cancer Chemopreventive Potential of Apples, Apple Juice, and Apple Components
2008
Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
2007
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors
2008
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors
2000
Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties
2010 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Fluorine in medicinal chemistry
2007 Standout
Recent progress in the discovery and development of cyclin-dependent kinase inhibitors
2005
Inhibition of tau phosphorylation: a new therapeutic strategy for the treatment of Alzheimer’s disease and other neurodegenerative disorders
2000
Anticancer effects of maple syrup phenolics and extracts on proliferation, apoptosis, and cell cycle arrest of human colon cells
2011
Which Metals are Green for Catalysis? Comparison of the Toxicities of Ni, Cu, Fe, Pd, Pt, Rh, and Au Salts
2016
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Reducing Stress on Cells with Apoferritin-Encapsulated Platinum Nanoparticles
2009
Aloisines, a New Family of CDK/GSK-3 Inhibitors. SAR Study, Crystal Structure in Complex with CDK2, Enzyme Selectivity, and Cellular Effects
2002
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Iodine/Palladium Approaches to the Synthesis of Polyheterocyclic Compounds
2010
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells
2012
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases
2004
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Recent Developments in the Preparation and Chemistry of Metallacycles and Metallacages via Coordination
2015 Standout
The specificities of protein kinase inhibitors: an update
2003 Standout
Iron-catalyzed oxidative homo-coupling of indoles via C–H cleavage
2010
Induction of Apoptosis in Cancer Cells by Bilberry (Vaccinium myrtillus) and the Anthocyanins
2002
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Concentrations of Anthocyanins in Common Foods in the United States and Estimation of Normal Consumption
2006 Standout
GSK-3: tricks of the trade for a multi-tasking kinase
2003 Standout
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
A Route to Annulated Indoles via a Palladium-Catalyzed Tandem Alkylation/Direct Arylation Reaction
2005
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
2004
N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2
2004
DNA Double-Strand Breaks
2002 StandoutNobel
Expression and isolation of antimicrobial small molecules from soil DNA libraries.
2001
Biomedical Importance of Indoles
2013 Standout
Anthocyanin/Polyphenolic–Rich Fruit Juice Reduces Oxidative Cell Damage in an Intervention Study with Patients on Hemodialysis
2008
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Recent advances in supramolecular and biological aspects of arene ruthenium(II) complexes
2013
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators
2007
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout
Works of Doris Marko being referenced
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells
2001
Apple polyphenols diminish the phosphorylation of the epidermal growth factor receptor in HT29 colon carcinoma cells
2007
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
2001
TDP1 Overexpression in Human Cells Counteracts DNA Damage Mediated by Topoisomerases I and II
2004
Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts
1998
Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder
2012
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
1999 Standout
Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
2009
Inhibitor Binding to Active and Inactive CDK2
2001
The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation
2004
Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression
2010
Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations
2011
Cyclic 3‘,5‘-Nucleotide Phosphodiesterases: Potential Targets for Anticancer Therapy
2000
The Anthocyanidins Cyanidin and Delphinidin Are Potent Inhibitors of the Epidermal Growth-Factor Receptor
2001
Apple Polyphenols Affect Protein Kinase C Activity and the Onset of Apoptosis in Human Colon Carcinoma Cells
2007
Cellular Uptake of Platinum Nanoparticles in Human Colon Carcinoma Cells and Their Impact on Cellular Redox Systems and DNA Integrity
2009
Modulation of Key Elements of the Wnt Pathway by Apple Polyphenols
2006
Methoxy-Substituted 3-Formyl-2-phenylindoles Inhibit Tubulin Polymerization
1998
Oak Ellagitannins Suppress the Phosphorylation of the Epidermal Growth Factor Receptor in Human Colon Carcinoma Cells
2008
Inhibitors of the epidermal growth factor receptor in apple juice extract
2005