Citation Impact
Citing Papers
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
2005
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
CpG Motifs in Bacterial DNA Activate Leukocytes Through the pH-Dependent Generation of Reactive Oxygen Species
1998
TLR9 Blockade Inhibits Activation of Diabetogenic CD8+ T Cells and Delays Autoimmune Diabetes
2010
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Signal Transduction Pathways in Macroautophagy
1997
Genetic analysis of resistance to viral infection
2007 StandoutNobel
Toll-like Receptors and Innate Immunity
2001
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Heterochronic Genes Control Cell Cycle Progress and Developmental Competence of C. elegans Vulva Precursor Cells
1996 StandoutNobel
Vitamin D Deficiency
2007 Standout
CpG DNA rescues B cells from apoptosis by activating NFκB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway
1999
Nucleic acid-incorporated azidonucleotides: Probes for studying the interaction of RNA or DNA with proteins and other nucleic acids
1993
Molecular Basis for ADP-induced Platelet Activation
1998
Toll-like receptors in systemic autoimmune disease
2006
3 The Medicinal Chemistry of the Azido Group
1994
Toll-Like Receptors and Activation of Autoreactive B Cells
2002
Mechanism of agonist and antagonist binding to .alpha.2 adrenergic receptors: evidence for a precoupled receptor-guanine nucleotide protein complex
1988
Direct Immunologic activities of CpG DNA and implications for gene therapy
1999
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
2004
FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T‐purinoceptors
1994
An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.
1995
The role of CpG motifs in innate immunity
2000
Bacterial CpG DNA Activates Immune Cells to Signal Infectious Danger
1999
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Receptors for ADP on human blood platelets
1994
CpG DNA and LPS induce distinct patterns of activation in human monocytes
1999
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
2006 StandoutNobel
A Comparison of Low-Molecular-Weight Heparin with Unfractionated Heparin for Unstable Coronary Artery Disease
1997 Standout
CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells
1999
Bacterial DNA as immune cell activator
1998
Differences in vitamin D status between countries in young adults and the elderly
1992
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides
2001
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
ADP is a potent inhibitor of human platelet plasma membrane adenylate cyclase
1979 StandoutNatureNobel
Tautomerism of 2-azidoadenine nucleotides Effects on enzyme kinetics and photoaffinity labeling
1984
ADP can induce aggregation of human platelets via both P2Y1 and P2T receptors
2000
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Regulation of Smad signaling by protein kinase C
2001
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.
1998
Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐ and pH‐dependent manner
2004
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Photoaffinity labeling of mitochondrial adenosine triphosphatase by [.alpha.-32P]2-azido ADP
1985
Identification and Biological Activity of the Active Metabolite of Clopidogrel
2000
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
1992
Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.
1987
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Cancer Cell Cycles
1996 StandoutScience
Cutting Edge: Rapid Induction of Mitogen-Activated Protein Kinases by Immune Stimulatory CpG DNA
1998
HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION
1977 StandoutNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
The significance of the circulating cancer cell
1975
Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP
1978
Ultrastructural Studies of Platelet Aggregates From Human Subjects Receiving Clopidogrel and From a Patient With an Inherited Defect of an ADP-Dependent Pathway of Platelet Activation
1996
A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation
1976 StandoutNobel
Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells.
1989
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
CpG Motifs in Bacterial DNA and Their Immune Effects
2002 Standout
Cutting Edge: Bacterial DNA and LPS Act in Synergy in Inducing Nitric Oxide Production in RAW 264.7 Macrophages
1999
G i regulation of secretory vesicle swelling examined by atomic force microscopy
1997
Prostacyclin is a circulating hormone
1978 StandoutNatureNobel
Characterization of Hepatitis C Virus (HCV) and HCV E2 Interactions with CD81 and the Low-Density Lipoprotein Receptor
2000
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
CpG DNA Rescue from Anti-IgM-Induced WEHI-231 B Lymphoma Apoptosis via Modulation of IκBα and IκBβ and Sustained Activation of Nuclear Factor-κB/c-Rel
1998
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 StandoutScience
Bacterial/CpG DNA Down-Modulates Colony Stimulating Factor-1 Receptor Surface Expression on Murine Bone Marrow-Derived Macrophages with Concomitant Growth Arrest and Factor-Independent Survival
1999
Adenine nucleotide binding sites on beef heart F1 ATPase: photoaffinity labeling of beta-subunit Tyr-368 at a noncatalytic site and beta Tyr-345 at a catalytic site.
1987 StandoutNobel
CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel.
1998
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
The Role of Cell Surface Receptors in the Activation of Human B Cells by Phosphorothioate Oligonucleotides
2000
Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction
1992 StandoutScience
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Low-Molecular-Weight Heparins
1997 Standout
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs
2001
CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
1999
Now I know my CpGs
2001
Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells
2000
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Nomenclature and classification of purinoceptors.
1994 Standout
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets
1977 StandoutNobel
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
1998
Structure of synaptogyrin (p29) defines novel synaptic vesicle protein.
1995 StandoutNobel
Photoaffinity labeling with 2-azidoadenosine diphosphate of a tight nucleotide binding site on chloroplast coupling factor 1
1982
ADP Receptors on Platelets
1996
Identification of amino acid residues photolabeled with 2-azido[.alpha.-32P]adenosine diphosphate in the .beta. subunit of beef heart mitochondrial F1-ATPase
1986
Extracellular ATP: effects, sources and fate
1986 Standout
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Donald E. Macfarlane being referenced
Stimulation of human platelet adenylate cyclase by prostaglandin D2
1974
Two dimensional benzyldimethyl-n-hexadecylammonium chloride → sodium dodecyl sulfate preparative polyacrylamide gel electrophoresis: A high capacity high resolution technique for the purification of proteins from complex mixtures
1989
Immunostimulatory CpG-oligodeoxynucleotides induce a factor that inhibits macrophage adhesion
1999
Chloroquine prevention of murine MHC-disparate acute graft-versus-host disease correlates with inhibition of splenic response to CpG oligodeoxynucleotides and alterations in T-cell cytokine production
2002
Efficacy and Safety of Enoxaparin to Prevent Deep Venous Thrombosis after Hip Replacement Surgery
1994
Protein kinase C is not necessary for transforming growth factor beta-induced growth-arrest in leukemia cell lines
1997
Lack of Immune Stimulation by Immobilized CpG-Oligodeoxynucleotide
1999
Unmethylated CpG‐containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step
1997
2-Methylthioadenosine [β-32P]diphosphate: Synthesis and use as probe of platelet ADP receptors
1992
Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides
1999
Direct detection of hepatitis C virus (HCV) RNA from whole blood, and comparison with HCV RNA in plasma and peripheral blood mononuclear cells
1995
Parallel observation of the occupancy of the alpha 2-adrenergic receptor in intact platelets and its ability to inhibit the adenylate cyclase.
1982
2-Methylthioadenosine[beta-32P]diphosphate. An agonist and radioligand for the receptor that inhibits the accumulation of cyclic AMP in intact blood platelets.
1983
The effects of ATP on platelets: evidence against the central role of released ADP in primary aggregation
1975
Malondialdehyde Production by Platelets during Secondary Aggregation
1977
Antagonism of Immunostimulatory CpG-Oligodeoxynucleotides by Quinacrine, Chloroquine, and Structurally Related Compounds
1998
Antagonism of Immunostimulatory CpG-Oligodeoxynucleotides by 4-Aminoquinolines and Other Weak Bases: Mechanistic Studies
1999
Binding of 2-azidoadenosine [.beta.-32P]diphosphate to the receptor on intact human blood platelets which inhibits adenylate cyclase
1982
Phorbol diester-induced phosphorylation of nuclear matrix proteins in HL60 promyelocytes. Possible role in differentiation studied by cationic detergent gel electrophoresis.
1986
Factors contributing to vitamin D status near retirement age.
1984
Inhibition by ADP of prostaglandin induced accumulation of cyclic AMP in intact human platelets.
1981
The Extraction and Separation of Activators and Inhibitors of Fibrinolysis from Bovine Endothelium and Mesothelium
1970
Attempts to Define a Platelet ADP Receptor with 203Hg-p-Mercuribenzene Sulphonate (MBS)
1977
Identification of phosphoprotein NP33 as a nucleus-associated ribosomal S6 protein and its phosphorylation in hematopoietic cells.
1990