Citation Impact
Citing Papers
Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis
2009 Science
Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance
2018 Standout
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
In silico prediction of protein-protein interactions in human macrophages
2014 Standout
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
2019 Standout
Trends in Utilization of Transarterial Treatments for Hepatocellular Carcinoma: Results of a Survey by the Italian Society of Interventional Radiology
2013
mRECIST for HCC: Performance and novel refinements
2020
Alpha-fetoprotein kinetics in patients with hepatocellular carcinoma receiving ramucirumab or placebo: an analysis of the phase 3 REACH study
2018
Cost-effectiveness of semi-annual surveillance for hepatocellular carcinoma in cirrhotic patients of the Italian Liver Cancer population
2012
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
Stereotactic body radiation therapy vs. radiofrequency ablation in Asian patients with hepatocellular carcinoma
2020
Orantinib versus placebo combined with transcatheter arterial chemoembolisation in patients with unresectable hepatocellular carcinoma (ORIENTAL): a randomised, double-blind, placebo-controlled, multicentre, phase 3 study
2017
NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
2016 Nature
Prospective Comparison of Spleen and Liver Stiffness by Using Shear-Wave and Transient Elastography for Detection of Portal Hypertension in Cirrhosis
2014
Hepatic stellate cells as key target in liver fibrosis
2017
Molecular diagnosis and treatment of drug-resistant hepatitis B virus
2014
Global epidemiology and genotype distribution of the hepatitis C virus infection
2014
Accuracy of Risk Scores for Patients With Chronic Hepatitis B Receiving Entecavir Treatment
2013
Microsatellite Instability in Colorectal Cancer
2010 Standout
Liver stiffness-based optimization of hepatocellular carcinoma risk score in patients with chronic hepatitis B
2013
Hepatocellular carcinoma
2016 Standout
Hepatocellular carcinoma
2018 Standout
Clinical utility of quantitative HBsAg in natural history and nucleos(t)ide analogue treatment of chronic hepatitis B: new trick of old dog
2012
Rheumatoid arthritis
2016 Standout
Mechanisms of hepatic stellate cell activation
2017 Standout
Infections in Patients With Cirrhosis Increase Mortality Four-Fold and Should Be Used in Determining Prognosis
2010
Y90 Radioembolization Significantly Prolongs Time to Progression Compared With Chemoembolization in Patients With Hepatocellular Carcinoma
2016
Accuracy of the Liver Imaging Reporting and Data System in Computed Tomography and Magnetic Resonance Image Analysis of Hepatocellular Carcinoma or Overall Malignancy—A Systematic Review
2018
The ART Score Is Not Effective to Select Patients for Transarterial Chemoembolization Retreatment in an Italian Series
2014
Liver Stiffness Is Associated With Risk of Decompensation, Liver Cancer, and Death in Patients With Chronic Liver Diseases: A Systematic Review and Meta-analysis
2013
Prognostic factors and predictors of sorafenib benefit in patients with hepatocellular carcinoma: Analysis of two phase III studies
2017
Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update
2008
Hepatitis B virus DNA levels and outcomes in chronic hepatitis B # †
2009
Hepatocellular carcinoma risk following direct-acting antiviral HCV therapy: A systematic review, meta-analyses, and meta-regression
2017
Comprehensive Analysis of Prognostic Alternative Splicing Signatures in Endometrial Cancer
2020
Locoregional therapies in the era of molecular and immune treatments for hepatocellular carcinoma
2021
Add-On Adefovir Is Superior to a Switch to Entecavir as Rescue Therapy for Lamivudine-Resistant Chronic Hepatitis B
2011
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
Hepatitis B virus basal core promoter mutations A1762T/G1764A are associated with genotype C and a low serum HBsAg level in chronically-infected HBeAg-positive Chinese patients
2012
Hepatitis B virus infection
2009 Standout
Hepatocellular carcinoma
2021 Standout
A global view of hepatocellular carcinoma: trends, risk, prevention and management
2019 Standout
Evaluation of ART Scores for Repeated Transarterial Chemoembolization in Japanese Patients with Hepatocellular Carcinoma
2015
The assessment of hepatocellular carcinoma risk in patients with chronic hepatitis B under antiviral therapy
2016
The role of quantitative hepatitis B surface antigen revisited
2016
Can we use HCC risk scores to individualize surveillance in chronic hepatitis B infection?
2015
Prediction Models of Long-Term Cirrhosis and Hepatocellular Carcinoma Risk in Chronic Hepatitis B Patients: Risk Scores Integrating Host and Virus Profiles
2013
Measurement of Spleen Stiffness to Evaluate Portal Hypertension and the Presence of Esophageal Varices in Patients With HCV-Related Cirrhosis
2012
Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma
2016
Detection of early portal hypertension with routine data and liver stiffness in patients with asymptomatic liver disease: A prospective study
2013
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
A predictive model for carcinogenesis in patients with chronic hepatitis B undergoing entecavir therapy and its validation
2016
Non invasive evaluation of portal hypertension using transient elastography
2011
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival
2019
Liver Imaging Reporting and Data System (LI-RADS) Version 2018: Imaging of Hepatocellular Carcinoma in At-Risk Patients
2018
Palliative external-beam radiotherapy for bone metastases from hepatocellular carcinoma
2014
Should AFP (or Any Biomarkers) Be Used for HCC Surveillance?
2017
Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis
2011
Efficacy of Tenofovir-based Rescue Therapy in Lamivudine-resistant Chronic Hepatitis B Patients With Failure of Lamivudine and Adefovir Combination
2015
Portal hypertensive bleeding in cirrhosis
2016 Standout
Cell-free nucleic acids as biomarkers in cancer patients
2011 Standout
Non-alcoholic fatty liver disease
2021 Standout
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2018
Liver cancer: Approaching a personalized care
2015
Pegylated Interferon‐α‐2a plus Ribavirin for Treatment‐Naive Asian Patients with Hepatitis C Virus Genotype 1 Infection: A Multicenter, Randomized Controlled Trial
2008
Hepatitis C virus infection
2017
Proton beam radiotherapy vs. radiofrequency ablation for recurrent hepatocellular carcinoma: A randomized phase III trial
2020
Role of antiviral treatment for HCC prevention
2014
Objective response by mRECIST as a predictor and potential surrogate end-point of overall survival in advanced HCC
2017
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Spleen stiffness measurement can predict clinical complications in compensated HCV-related cirrhosis: A prospective study
2014
Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma
2012 Standout
Development of models estimating the risk of hepatocellular carcinoma after antiviral treatment for hepatitis C
2018
Then and now: The progress in hepatitis B treatment over the past 20 years
2014
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
2009 StandoutNature
Comparison of the Efficacy of Lamivudine Plus Adefovir Versus Entecavir in the Treatment of Lamivudine-Resistant Chronic Hepatitis B: A Systematic Review and Meta-Analysis
2013
Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis
2013 Standout
Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
2011
Hepatitis B virus infection
2018
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
2012 Standout
Prognostic Value of Controlled Attenuation Parameter by Transient Elastography
2017
Risk of hepatitis B virus reactivation in rheumatoid arthritis patients undergoing biologic treatment: Extending perspective from old to newer drugs
2015
Sorafenib in combination with transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma (TACE 2): a randomised placebo-controlled, double-blind, phase 3 trial
2017
Impact of age and gender on risk of hepatocellular carcinoma after hepatitis B surface antigen seroclearance
2017
Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
2008
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Molecular therapies and precision medicine for hepatocellular carcinoma
2018
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Comparative performance of risk prediction models for hepatitis B-related hepatocellular carcinoma in the United States
2021
On-treatment alpha-fetoprotein is a specific tumor marker for hepatocellular carcinoma in patients with chronic hepatitis B receiving entecavir
2013
Risk of hepatocellular carcinoma in chronic hepatitis B: Assessment and modification with current antiviral therapy
2015
Hepatocellular Carcinoma
2011 Standout
<p>Image-Guided Percutaneous Microwave Ablation Versus Cryoablation For Hepatocellular Carcinoma In High-Risk Locations: Intermediate-Term Results</p>
2019
External Beam Radiation Therapy for Primary Liver Cancers: An ASTRO Clinical Practice Guideline
2021
Natural history of acute and chronic hepatitis B: The role of HBV genotypes and mutants
2017
Treatment of Liver Tumors with Lipiodol TACE: Technical Recommendations from Experts Opinion
2015
Incidence and predictors of hepatocellular carcinoma in Caucasian chronic hepatitis B patients receiving entecavir or tenofovir
2014
Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA
2016 StandoutNobel
Surveillance for hepatocellular carcinoma
2016
Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection
2013
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Hepatocellular carcinoma
2022 Standout
Elastography, Spleen Size, and Platelet Count Identify Portal Hypertension in Patients With Compensated Cirrhosis
2012
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Hepatocellular Carcinoma
2019 Standout
AASLD guidelines for the treatment of hepatocellular carcinoma
2017 Standout
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
Extensively Drug-Resistant Tuberculosis: A New Face to an Old Pathogen
2009
Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma
2019
Transarterial chemoembolization (TACE) plus percutaneous ethanol injection (PEI) for the treatment of unresectable hepatocellular carcinoma: a meta-analysis of randomized controlled trials.
2015
Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for hepatocellular carcinoma: a meta-analysis
2021
Clinical patterns of hepatocellular carcinoma in nonalcoholic fatty liver disease: A multicenter prospective study
2015
A carbohydrate-grafted nanovesicle with activatable optical and acoustic contrasts for dual modality high performance tumor imaging
2014
Next-Generation Sequencing: From Understanding Biology to Personalized Medicine
2013
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
APASL and AASLD Consensus Guidelines on Imaging Diagnosis of Hepatocellular Carcinoma: A Review
2011
Impact of long‐term tenofovir disoproxil fumarate on incidence of hepatocellular carcinoma in patients with chronic hepatitis B
2015
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality
2020
A Recombinant Hepatitis C Virus Genotype 1a E1/E2 Envelope Glycoprotein Vaccine Elicits Antibodies That Differentially Neutralize Closely Related 2a Strains through Interactions of the N-Terminal Hypervariable Region 1 of E2 with Scavenger Receptor B1
2019 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Comparative Effectiveness of Entecavir Versus Tenofovir for Preventing Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: A Systematic Review and Meta‐Analysis
2020
Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome
2018
Hepatitis C virus core antigen testing in liver and kidney transplant recipients
2013
Trial Design and Endpoints in Hepatocellular Carcinoma: AASLD Consensus Conference
2020
Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
2018 Standout
Adding adefovir vs. switching to entecavir for lamivudine‐resistant chronic hepatitis B (ACE study): a 2‐year follow‐up randomized controlled trial
2012
EASL Recommendations on Treatment of Hepatitis C 2018
2018 Standout
Stereotactic ablative radiotherapy for hepatocellular carcinoma: A systematic review and meta‐analysis of local control, survival and toxicity outcomes
2021
Effects of Entecavir and Tenofovir on Renal Function in Patients with Hepatitis B Virus-Related Compensated and Decompensated Cirrhosis
2017
Surveillance for hepatocellular carcinoma
2014
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Clinical Utility of HCV Core Antigen Detection and Quantification in the Diagnosis and Management of Patients with Chronic Hepatitis C Receiving an All-Oral, Interferon-Free Regimen
2016
Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells
2018
Global cancer statistics, 2012
2015 Standout
Liver stiffness plus platelet count can be used to exclude high‐risk oesophageal varices
2015
Randomized, Multicenter, Open-Label Study of Oxaliplatin Plus Fluorouracil/Leucovorin Versus Doxorubicin As Palliative Chemotherapy in Patients With Advanced Hepatocellular Carcinoma From Asia
2013
Transient elastography: a meta‐analysis of diagnostic accuracy in evaluation of portal hypertension in chronic liver disease
2012
Clinical features and treatment efficacy of peginterferon alfa plus ribavirin in chronic hepatitis C patients coinfected with hepatitis B virus
2011
Therapies for patients with hepatocellular carcinoma awaiting liver transplantation: A systematic review and meta‐analysis
2017
Diagnostic and therapeutic progress of multi-drug resistance with anti-HBV nucleos(t)ide analogues
2012
Comparison of diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis‐4 index for detecting liver fibrosis in adult patients with chronic hepatitis B virus infection: A systemic review and meta‐analysis
2014
Transcatheter Arterial Chemoembolization Plus Radiotherapy Compared With Chemoembolization Alone for Hepatocellular Carcinoma
2015
Hepatitis C Core Antigen Testing for Diagnosis of Hepatitis C Virus Infection
2016
Current and Emerging Tools for Hepatocellular Carcinoma Surveillance
2021
Blood Tests to Diagnose Fibrosis or Cirrhosis in Patients With Chronic Hepatitis C Virus Infection
2013
Liver stiffness‐based score in hepatoma risk assessment for chronic hepatitis C patients after successful antiviral therapy
2016
Works of Do Young Kim being referenced
Proteomic and Lipidomic Signatures of Lipid Metabolism in NASH-Associated Hepatocellular Carcinoma
2013
[Peginterferon alfa-2a plus ribavirin for initial treatment of chronic hepatitis C in Korea].
2006
Lamivudine Maintenance Beyond One Year After Hbeag Seroconversion Is A Major Factor for Sustained Virologic Response in Hbeag-Positive Chronic Hepatitis B
2009
Role of <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography in Detecting Extrahepatic Metastasis in Pretreatment Staging of Hepatocellular Carcinoma
2007
Epidemiology and Surveillance of Hepatocellular Carcinoma
2012
Retrospective comparison of EASL 2018 and LI-RADS 2018 for the noninvasive diagnosis of hepatocellular carcinoma using magnetic resonance imaging
2019
Prediction of Development of Liver-Related Events by Transient Elastography in Hepatitis B Patients With Complete Virological Response on Antiviral Therapy
2014
Prevalence and genotype distribution of hepatitis C virus among apparently healthy individuals in Mongolia: a population‐based nationwide study
2008
Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score
2011
Prediction of Liver-Related Events Using Fibroscan in Chronic Hepatitis B Patients Showing Advanced Liver Fibrosis
2012
Prediction of Significant Fibrosis in Chronic Hepatitis C Patients with Normal ALT
2011
Cryoablation of Hepatocellular Carcinoma with High-Risk for Percutaneous Ablation: Safety and Efficacy
2016
How to Improve Treatment Outcomes for Hepatocellular Carcinoma of Intermediate and Advanced Stage
2012
Efficacy of adefovir add‐on lamivudine rescue therapy compared with switching to entecavir monotherapy in patients with lamivudine‐resistant chronic hepatitis B
2010
Persistent hepatitis B viral replication affects recurrence of hepatocellular carcinoma after curative resection
2007
Phase I/II trial of helical IMRT-based stereotactic body radiotherapy for hepatocellular carcinoma
2018
Dose escalation in radiotherapy for incomplete transarterial chemoembolization of hepatocellular carcinoma
2019
Hepatocellular carcinoma presenting with bone metastasis: clinical characteristics and prognostic factors
2008
Clinical characteristics and prognosis of hepatocellular carcinoma with different sets of serum AFP and PIVKA-II levels
2012
Quantitative hepatitis B surface antigen and hepatitis B e antigen titers in prediction of treatment response to entecavir
2011
Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: The SPACE trial
2016
Clinical features and prognosis of hepatocellular carcinoma with respect to pre‐S deletion and basal core promoter mutations of hepatitis B virus Genotype C2
2011
Combination of preS Deletions and A1762T/G1764A Mutations in HBV Subgenotype C2 Increases the Risk of Developing HCC
2011
A Liver Stiffness Measurement-Based, Noninvasive Prediction Model for High-Risk Esophageal Varices in B-Viral Liver Cirrhosis
2010
A randomized, open-label study comparing low-dose clevudine plus adefovir combination therapy with clevudine monotherapy in naïve chronic hepatitis B patients
2014
Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model
2015
Retrospective analysis of stereotactic body radiation therapy efficacy over radiofrequency ablation for hepatocellular carcinoma
2018
Milan criteria are useful predictors for favorable outcomes in hepatocellular carcinoma patients undergoing liver transplantation after transarterial chemoembolization
2006
Early α-fetoprotein response as a predictor for clinical outcome after localized concurrent chemoradiotherapy for advanced hepatocellular carcinoma
2010
Survival of Hepatocellular Carcinoma Patients May be Improved in Surveillance Interval not More Than 6 Months Compared With More Than 6 Months
2013
Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats
2009
Extensively Drug-Resistant Tuberculosis in South Korea: Risk Factors and Treatment Outcomes among Patients at a Tertiary Referral Hospital
2007
Complete response at first chemoembolization is still the most robust predictor for favorable outcome in hepatocellular carcinoma
2015
Lower Incidence of Hepatocellular Carcinoma and Cirrhosis in Hepatitis C Patients with Sustained Virological Response by Pegylated Interferon and Ribavirin
2014
Long‐term clinical outcome of large volume paracentesis with intravenous albumin in patients with spontaneous bacterial peritonitis: A randomized prospective study
2005
Specific mutations in the enhancer II/core promoter/precore regions of hepatitis B virus subgenotype C2 in Korean patients with hepatocellular carcinoma
2009
Risk Assessment of Development of Hepatic Decompensation in Histologically Proven Hepatitis B Viral Cirrhosis Using Liver Stiffness Measurement
2012
Sorafenib with or without concurrent transarterial chemoembolization in patients with advanced hepatocellular carcinoma: The phase III STAH trial
2018
A multicenter study of entecavir vs. tenofovir on prognosis of treatment-naïve chronic hepatitis B in South Korea
2019
Reproducibility of European Association for the Study of the Liver criteria and modified Response Evaluation Criteria in Solid Tumors in patients treated with sorafenib
2018
Radiological response predicts survival following transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma
2012
Clinical usefulness of double biomarkers AFP and PIVKA ‐II for subdividing prognostic groups in locally advanced hepatocellular carcinoma
2013
[A prospective study on the prevalence and clinical significance of autoantibodies in patients with suspected nonalcoholic fatty liver disease].
2005
Liver stiffness‐based model for prediction of hepatocellular carcinoma in chronic hepatitis B virus infection: comparison with histological fibrosis
2014
Liver Stiffness Measurement Using Acoustic Radiation Force Impulse (ARFI) Elastography and Effect of Necroinflammation
2012
Sorafenib versus cytotoxic chemotherapy for patients with advanced hepatocellular carcinoma: a retrospective, single-institution study
2011
Risk assessment of clinical outcomes in Asian patients with chronic hepatitis B using enhanced liver fibrosis test
2014
Clinical outcomes and prognostic factors of patients with advanced hepatocellular carcinoma treated with sorafenib as first‐line therapy: A K orean multicenter study
2014
Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B
2015
Applicability of BCLC stage for prognostic stratification in comparison with other staging systems: single centre experience from long‐term clinical outcomes of 1717 treatment‐naïve patients with hepatocellular carcinoma
2012
Long-term adefovir dipivoxil monotherapy for up to 5 years in lamivudine-resistant chronic hepatitis B
2010
New Automated Hepatitis C Virus (HCV) Core Antigen Assay as an Alternative to Real-Time PCR for HCV RNA Quantification
2010
Sarcopenia is associated with significant liver fibrosis independently of obesity and insulin resistance in nonalcoholic fatty liver disease: Nationwide surveys (KNHANES 2008‐2011)
2015
Autologous Bone Marrow Infusion Activates the Progenitor Cell Compartment in Patients with Advanced Liver Cirrhosis
2010
Chronic HBV infection with persistently normal ALT b. not to treat
2008
Therapeutic benefit of radiotherapy in huge (≥10 cm) unresectable hepatocellular carcinoma
2013
Curative Resection of Single Primary Hepatic Malignancy: Liver Imaging Reporting and Data System Category LR-M Portends a Worse Prognosis
2017
Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with transient elastography–defined subclinical cirrhosis
2015