Standout Papers

Functional insights from the structure of the 30S ribosomal subunit and its interactions with ... 2000 2026 2008 2017 1.6k
  1. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics (2000)
    Andrew P. Carter, William Clemons et al. Nature
  2. Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit (2001)
    J.M. Ogle, Ditlev E. Brodersen et al. Science
  3. Structure of the 30S ribosomal subunit (2000)
    Ditlev E. Brodersen, William Clemons et al. Biochemical Society Transactions
  4. Structure of the 30S ribosomal subunit (2000)
    Brian T. Wimberly, Ditlev E. Brodersen et al. Nature
  5. Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA (2002)
    Ditlev E. Brodersen, William Clemons et al. Journal of Molecular Biology
  6. Crystal Structure of an Initiation Factor Bound to the 30 S Ribosomal Subunit (2001)
    Andrew P. Carter, William Clemons et al. Science
  7. The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit (2000)
    Ditlev E. Brodersen, William Clemons et al. Cell
  8. Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon (2005)
    Sabine Petry, Ditlev E. Brodersen et al. Cell
  9. The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE (2009)
    Cajetan Neubauer, Yong‐Gui Gao et al. Cell
  10. Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination (2001)
    William Clemons, Ditlev E. Brodersen et al. Journal of Molecular Biology
  11. Atomic Structures of the 30S Subunit and Its Complexes with Ligands and Antibiotics (2001)
    Ditlev E. Brodersen, Andrew P. Carter et al. Cold Spring Harbor Symposia on Quantitative Biology
  12. Phasing the 30S ribosomal subunit structure (2003)
    Ditlev E. Brodersen, William Clemons et al. Acta Crystallographica Section D Biological Crystallography

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Ribosome as a molecular machine
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A Model for How Ribosomal Release Factors Induce Peptidyl-tRNA Cleavage in Termination of Protein Synthesis
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What recent ribosome structures have revealed about the mechanism of translation
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The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
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GTPase activation of elongation factor EF‐Tu by the ribosome during decoding
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A hierarchical model for evolution of 23S ribosomal RNA
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Release Factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies
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Structural basis for translation termination on the 70S ribosome
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The Path of Messenger RNA through the Ribosome
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Rapid Kinetic Analysis of EF-G-dependent mRNA Translocation in the Ribosome
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Crystal Structure of the Ribosome at 5.5 Å Resolution
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What we have learned from ribosome structures
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Ribosome structure: revisiting the connection between translational accuracy and unconventional decoding
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Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
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23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
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Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
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Visualization of protein S1 within the 30S ribosomal subunit and its interaction with messenger RNA
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Crystal structure of a translation termination complex formed with release factor RF2
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The Structural Basis of Large Ribosomal Subunit Function
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Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM
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The Search and Its Outcome: High-Resolution Structures of Ribosomal Particles from Mesophilic, Thermophilic, and Halophilic Bacteria at Various Functional States
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Single-Molecule RNA Science
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Structural basis for mRNA and tRNA positioning on the ribosome
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Ribosomal Translocation: One Step Closer to the Molecular Mechanism
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A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
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Structural basis for selectivity and toxicity of ribosomal antibiotics
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The Mechanism for Activation of GTP Hydrolysis on the Ribosome
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Peptide Release on the Ribosome: Mechanism and Implications for Translational Control
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The Molecular Mechanics of Eukaryotic Translation
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How Should We Think About the Ribosome?
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Intersubunit movement is required for ribosomal translocation
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Mechanism of peptide bond synthesis on the ribosome
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Deleterious mutations in small subunit ribosomal RNA identify functional sites and potential targets for antibiotics
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Pseudouridines and Pseudouridine Synthases of the Ribosome
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Structural basis for TetM-mediated tetracycline resistance
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Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy
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The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Single-Particle Imaging of Macromolecules by Cryo-Electron Microscopy
2002 StandoutNobel
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Irreversible chemical steps control intersubunit dynamics during translation
2008
EF-G-Dependent GTPase on the Ribosome. Conformational Change and Fusidic Acid Inhibition
2006
An Unbiased cDNA Library Prepared from IsolatedAplysiaSensory Neuron Processes Is Enriched for Cytoskeletal and Translational mRNAs
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Functional aspects of ribosomal architecture: symmetry, chirality and regulation
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RIBOSOME DYNAMICS: Insights from Atomic Structure Modeling into Cryo-Electron Microscopy Maps
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Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit
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X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli
2003
Mechanisms of elongation on the ribosome: dynamics of a macromolecular machine
2004
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
2010
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination
2007
RNA Structure: Reading the Ribosome
2005 Science
An Active Role for tRNA in Decoding Beyond Codon:Anticodon Pairing
2005 Science
Fidelity of Aminoacyl-tRNA Selection on the Ribosome: Kinetic and Structural Mechanisms
2001
Structural Basis of the Translational Elongation Cycle
2013 Nobel
tRNA dynamics on the ribosome during translation
2004 Nobel
Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics
2004 StandoutNobel
STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY
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Fidelity at the Molecular Level: Lessons from Protein Synthesis
2009
Stop Codon Recognition by Release Factors Induces Structural Rearrangement of the Ribosomal Decoding Center that Is Productive for Peptide Release
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Macrolide antibiotic interaction and resistance on the bacterial ribosome.
2003
The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution
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Ribosomal Protection Proteins and Their Mechanism ofTetracyclineResistance
2003

Works of Ditlev E. Brodersen being referenced

Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA 1 1 Edited by R. Huber
2002 Nobel
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
2000 StandoutNatureNobel
Cyanobacteria contain a structural homologue of the Hfq protein with altered RNA‐binding properties
2009
Structure of the 30S ribosomal subunit
2000 StandoutNatureNobel
The social life of ribosomal proteins
2005
The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit
2000 StandoutNobel
Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity
2018
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination
2001 StandoutNobel
Atomic Structures of the 30S Subunit and Its Complexes with Ligands and Antibiotics
2001 StandoutNobel
Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon
2005 StandoutNobel
Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA
2002 StandoutNobel
Crystal Structure of an Initiation Factor Bound to the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Structure of the 30S ribosomal subunit
2000 StandoutNobel
Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B
2003
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