Standout Papers

The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatro... 1997 2026 2006 2016 41
  1. The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement (1997)
    Johann Mulzer, Jan W. Bats et al. Synlett

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Iron-catalyzed cross-coupling reaction: recyclable heterogeneous iron catalyst for selective olefination of aryl iodides in poly(ethylene glycol) medium
2013
Synthesis of Chiral Cyclopentenones
2016
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Azobenzenes—synthesis and carbohydrate applications
2009
Bright Ion Channels and Lipid Bilayers
2013 StandoutNobel
Unraveling the Photoswitching Mechanism in Donor–Acceptor Stenhouse Adducts
2016 StandoutNobel
Photoisomerization of an Individual Azobenzene Molecule in Water: An On−Off Switch Triggered by Light at a Fixed Wavelength
2006
Anodic Coupling Reactions:  A Sequential Cyclization Route to the Arteannuin Ring Skeleton
2007
Reversibly Switching Bilayer Permeability and Release Modules of Photochromic Polymersomes Stabilized by Cooperative Noncovalent Interactions
2015
Photocontrol of Neural Activity: Biophysical Mechanisms and Performance in Vivo
2008
A Formal Total Synthesis of the Salicylihalamides
2003
Switching of an Azobenzene-Tripod Molecule on Ag(111)
2016
Waste Management of Chemically Activated Switches: Using a Photoacid To Eliminate Accumulation of Side Products
2014
Transition‐Metal‐Catalyzed Direct C–H Alkenylation, Alkynylation, Benzylation, and Alkylation of (Hetero)arenes
2010
Stereospecific Suzuki−Miyaura Coupling of Chiral α-(Acylamino)benzylboronic Esters with Inversion of Configuration
2010
Total Syntheses of Amphidinolide X and Y
2006
Short‐Circuiting Azobenzene Photoisomerization with Electron‐Donating Substituents and Reactivating the Photochemistry with Chemical Modification
2011
Design of higher valency in covalent organic frameworks
2020 StandoutScienceNobel
Red, far-red, and near infrared photoswitches based on azonium ions
2015
Chemoenzymatic enantiodivergent total syntheses of (+)- and (−)-codeine
2009
Total Synthesis of (+)-Phomactin A Using a B-Alkyl Suzuki Macrocyclization
2003
Ortho‐Chinonmethide als reaktive Intermediate in asymmetrischen Brønsted‐Säure‐katalysierten Cycloadditionen mit Alkenen mittels exklusiver Aktivierung des Elektrophils
2015
Iron(III) Salt‐Catalyzed Nazarov Cyclization/Michael Addition of Pyrrole Derivatives
2008
Electrochemically Mediated Oxidative Transformations of Substituted 4-Methoxystilbenes: Effect of Ortho-Substituted Nucleophilic Groups
2017
Red-Shifting Azobenzene Photoswitches for in Vivo Use
2015 Standout
Biologically Active Molecules with a “Light Switch”
2006
Asymmetric Nazarov Cyclizations Catalyzed by Chiral‐at‐Metal Complexes
2018
Efficient and Selective Syntheses of (all-E)- and (6E,10Z)-2′-O-Methylmyxalamides D via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy
2008 StandoutNobel
Electrochemical Amination of Less‐Activated Alkylated Arenes Using Boron‐Doped Diamond Anodes
2016
Cross Coupling Reactions of Chiral Secondary Organoboronic Esters With Retention of Configuration
2009
Asymmetric Boronate Addition to o-Quinone Methides: Ligand Exchange, Solvent Effects, and Lewis Acid Catalysis
2015

Works of Dirk Trauner being referenced

Optical control of insulin release using a photoswitchable sulfonylurea
2014
Photoswitchable fatty acids enable optical control of TRPV1
2015
Pharmacology of ionotropic glutamate receptors: A structural perspective
2010
Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist
2015
New photochemical tools for controlling neuronal activity
2009
Biomimetic synthesis of the IDO inhibitors exiguamine A and B
2008
Development of an Iron(II)‐Catalyzed Aerobic Catechol Cleavage and Biomimetic Synthesis of Betanidin
2014
A Photochromic Agonist for μ‐Opioid Receptors
2014
Total Synthesis of Coralloidolides A, B, C, and E
2010
Light-activated ion channels for remote control of neuronal firing
2004
Mechanistic Investigations of the Acid‐Catalyzed Cyclization of a Vinyl ortho‐Quinone Methide
2008
Photochemical Restoration of Visual Responses in Blind Mice
2012
Photochemical control of endogenous ion channels and cellular excitability
2008
Optical control of metabotropic glutamate receptors
2013
Photochromic Blockers of Voltage‐Gated Potassium Channels
2009
The in vivo chemistry of photoswitched tethered ligands
2014
Concise Total Syntheses of Variecolortides A and B through an Unusual Hetero‐Diels–Alder Reaction
2010
Remote Control of Neuronal Activity with a Light-Gated Glutamate Receptor
2007
Optical Control of TRPV1 Channels
2013
Controlling epithelial sodium channels with light using photoswitchable amilorides
2014
Azo‐Propofols: Photochromic Potentiators of GABAAReceptors
2012
Regulating Enzymatic Activity with a Photoswitchable Affinity Label
2007
The crystal structure of the Dess–Martin periodinane
2012
Optical Control of Acetylcholinesterase with a Tacrine Switch
2014
Biomimetic Synthesis of (−)‐Pycnanthuquinone C through the Diels–Alder Reaction of a Vinyl Quinone
2010
Allosteric control of an ionotropic glutamate receptor with an optical switch
2005
Photochemical tools for remote control of ion channels in excitable cells
2005
Synthetic approaches toward sesterterpenoids
2012
Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death
2015
Catalysis of 6π Electrocyclizations
2008
Reversible Photomechanical Switching of Individual Engineered Molecules at a Metallic Surface
2007
Exploring the Pharmacology and Action Spectra of Photochromic Open‐Channel Blockers
2012
Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors
2012
An eight-step synthesis of epicolactone reveals its biosynthetic origin
2015
Optical Control of Insulin Secretion Using an Incretin Switch
2015
Concise Total Synthesis of (−)-Frondosin B Using a Novel Palladium-Catalyzed Cyclization
2002
The Total Synthesis of (−)‐Nitidasin
2014
Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel
2010
The Total Synthesis of (−)-Amathaspiramide F
2002
Optogenetic dissection of a behavioural module in the vertebrate spinal cord
2009 Nature
Biomimetic Total Synthesis of Santalin Y
2015
Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells
2014
Light-Induced Depolarization of Neurons Using a Modified Shaker K+ Channel and a Molecular Photoswitch
2006
LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness
2011
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
2010
A structural link between inactivation and block of a K+ channel
2008
Tuning Photochromic Ion Channel Blockers
2011
A Photochromic Agonist of AMPA Receptors
2012
Optochemical Genetics
2011
Rapid optical control of nociception with an ion-channel photoswitch
2012
The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis
2001
Protein Surface Recognition by Rational Design:  Nanomolar Ligands for Potassium Channels
2003
Practical synthesis of (?)-morphine
1999
Functionalized azobenzenes through cross-coupling with organotrifluoroborates
2007
Ein photochromer Agonist für μ‐Opioidrezeptoren
2014
New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids
1998
Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor
2007
Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-3-ones
2003
Totalsynthese von Coralloidolid A, B, C und E
2010
Total Synthesis of (−)-SNF4435 C and (+)-SNF4435 D
2005
Synthesis of Taiwaniaquinoids via Nazarov Triflation
2006
Azo‐Propofols: Photochromic Potentiators of GABAAReceptors
2012
Palladium-catalyzed couplings to nucleophilic heteroarenes: the total synthesis of (−)-frondosin B
2004
Extraction of Photogenerated Electrons and Holes from a Covalent Organic Framework Integrated Heterojunction
2014
Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine
2014
Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR
2009
Pericyclic Reactions of Prenylated Naphthoquinones:  Biomimetic Syntheses of Mollugin and Microphyllaquinone
2005
Photochrome Liganden für spannungsgesteuerte Kaliumkanäle
2009
Synthetic Studies toward the Guanacastepenes
2003
Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia
2005
Synthesis of Redshifted Azobenzene Photoswitches by Late‐Stage Functionalization
2016
Engineering Light-Gated Ion Channels
2006
Rational Design of a Chiral Palladium(0) Olefin Complex of Unprecedented Stability
2005
Concise Total Synthesis of (−)-Frondosin B Using a Novel Palladium-Catalyzed Cyclization This work was supported by a generous gift from Merck & Co.
2002
A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function
2015
2002
Formal Total Synthesis of (—)‐Morphine by Cuprate Conjugate Addition
1996
Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels
2009
A Red-Shifted, Fast-Relaxing Azobenzene Photoswitch for Visible Light Control of an Ionotropic Glutamate Receptor
2013
Catalysis of 6π Electrocyclizations
2008
An Electrochemical Approach to the Guanacastepenes
2005
Optische Kontrolle der Insulinsekretion mit einem Inkretinschalter
2015
Total Synthesis of (±)-Rhazinal Using Novel Palladium-Catalyzed Cyclizations
2009
Total Synthesis of (−)-Archazolid B
2007
Optische Kontrolle von TRPV1‐Kanälen
2013
Total Synthesis of (+)-Halichlorine: An Inhibitor of VCAM-1 Expression
1999
Kompakte Totalsynthese von Variecolortid A und B durch eine ungewöhnliche Hetero‐Diels‐Alder‐Reaktion
2010
A Roadmap to Success in Photopharmacology
2015
Development of novel Lewis acid catalyzed cycloisomerizations: synthesis of bicyclo[3.1.0]hexenes and cyclopentenones
2003
Synthesis of Enantiomerically Pure Morphine Alkaloids:  The Hydrophenanthrene Route
1998
All Optical Interface for Parallel, Remote, and Spatiotemporal Control of Neuronal Activity
2007
DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese
2001
Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative
2014
ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B
2008
Toward the Total Synthesis of Maoecrystal V: Establishment of Contiguous Quaternary Stereocenters
2010
Synthetic Studies toward SNF4435 C and SNF4435 D
2002
Enantioselective Nazarov Reactions through Catalytic Asymmetric Proton Transfer
2004
Concise Synthesis of (±)-Rhazinilam through Direct Coupling
2005
Stereoselective Syntheses of the Bioactive Polypropionates Aureothin, N-Acetylaureothamine, and Aureonitrile
2005
Optische Kontrolle der Acetylcholinesterase mit einem schaltbaren Tacrin
2014
Reversibly Caged Glutamate:  A Photochromic Agonist of Ionotropic Glutamate Receptors
2006
Optogenetic photochemical control of designer K+channels in mammalian neurons
2011
Stereoselective Synthesis of Cyercene A and the Placidenes
2005
Concise Total Synthesis of (−)-Frondosin B Using a Novel Palladium-Catalyzed Cyclization
2002
Optochemische Genetik
2011
Biosynthetic and Biomimetic Electrocyclizations
2005
Biomimetische Synthese von (−)‐Pycnanthuchinon C über eine Vinylchinon‐Diels‐Alder‐Reaktion
2010
Synthetic Studies toward the Haouamines
2005
Total Synthesis of (−)-Heptemerone B and (−)-Guanacastepene E
2006
The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement
1997 StandoutNobel
A Unified Approach to trans-Hydrindane Sesterterpenoids
2012
Exploring Biosynthetic Relationships among Furanocembranoids:  Synthesis of (−)-Bipinnatin J, (+)-Intricarene, (+)-Rubifolide, and (+)-Isoepilophodione B
2006
Expedient Synthesis of (±)-Bipinnatin J
2005
Biomimetic Synthesis of the Shimalactones
2007
Development of a Friedel−Crafts Triflation
2006
Morphine Synthesis and Biosynthesis-An Update
2000
Rankless by CCL
2026