Citation Impact
Citing Papers
A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
2002 Standout
Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases
2002
Lipopeptide Production in Pseudomonas sp. Strain DSS73 Is Regulated by Components of Sugar Beet Seed Exudate via the Gac Two-Component Regulatory System
2002
Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
2004 Standout
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing
2012 Standout
Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
2007
antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation
2023 Standout
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Biological control of soil-borne pathogens by fluorescent pseudomonads
2005 Standout
Structural aspects of non-ribosomal peptide biosynthesis
2004
Bacteriocins: developing innate immunity for food
2005 Standout
Crystal structure of the surfactin synthetase-activating enzyme Sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily
1999
Plant diversity enhances ecosystem responses to elevated CO2 and nitrogen deposition
2001 Nature
Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin
1998
Going back to the roots: the microbial ecology of the rhizosphere
2013 Standout
Yersiniabactin Synthetase
2002
Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum
2000
Directed evolution: new parts and optimized function
2009 StandoutNobel
Marine natural products
1990 Standout
Identification and analysis of the chivosazol biosynthetic gene cluster from the myxobacterial model strain Sorangium cellulosum So ce56
2005
Nanomolar inhibition of the enterobactin biosynthesis enzyme, EntE: Synthesis, substituent effects, and additivity
2006
Identification of Peptaibols from Trichoderma virens and Cloning of a Peptaibol Synthetase
2002
antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
2011 Standout
Aminomutases: mechanistic diversity, biotechnological applications and future perspectives
2011 StandoutNobel
Directed evolution: the ‘rational’ basis for ‘irrational’ design
2000
Characterization of the ferrichrome A biosynthetic gene cluster in the homobasidiomyceteOmphalotus olearius
2005
What have we learned from 15 years of free‐air CO2 enrichment (FACE)? A meta‐analytic review of the responses of photosynthesis, canopy properties and plant production to rising CO2
2004 Standout
Cytochrome P450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
2003 StandoutNobel
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Assembly of aryl‐capped siderophores by modular peptide synthetases and polyketide synthases
2000
The dhb Operon of Bacillus subtilisEncodes the Biosynthetic Template for the Catecholic Siderophore 2,3-Dihydroxybenzoate-Glycine-Threonine Trimeric Ester Bacillibactin
2001
Initiation, elongation, and termination strategies in polyketide and polypeptide antibiotic biosynthesis
1999
Lantibiotics and microcins: polypeptides with unusual chemical diversity
2000
The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases
1999
Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains
2000
Coelichelin, a new peptide siderophore encoded by theStreptomyces coelicolorgenome: structure prediction from the sequence of its non-ribosomal peptide synthetase
2000
Chapter 15 Heterologous Production of Polyketides in Bacteria
2009
Metabolic diversity in myxobacteria: identification of the myxalamid and the stigmatellin biosynthetic gene cluster of Stigmatella aurantiaca Sg a15 and a combined polyketide-(poly)peptide gene cluster from the epothilone producing strain Sorangium cellulosum So ce90
1999
The Biosynthesis of the Aromatic Myxobacterial Electron Transport Inhibitor Stigmatellin Is Directed by a Novel Type of Modular Polyketide Synthase
2002
The biofilm matrix
2010 Standout
Cloning, Expression, and Characterization of a Human 4′-Phosphopantetheinyl Transferase with Broad Substrate Specificity
2003
A global synthesis reveals biodiversity loss as a major driver of ecosystem change
2012 StandoutNature
Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis
2005
The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases
1999
Inhibition of aryl acid adenylation domains involved in bacterial siderophore synthesis
2005
The World of β‐ and γ‐Peptides Comprised of Homologated Proteinogenic Amino Acids and Other Components
2004
Natural roles of biosurfactants
2001
Identification of new, conserved, non‐ribosomal peptide synthetases from fluorescent pseudomonads involved in the biosynthesis of the siderophore pyoverdine
2002
Enzymatic Generation of the Antimetabolite γ,γ-Dichloroaminobutyrate by NRPS and Mononuclear Iron Halogenase Action in a Streptomycete
2006
Cyanobacterial peptides — Nature's own combinatorial biosynthesis
2006
Biosynthesis of Natural Products on Modular Peptide Synthetases
2001
Inhibition of the D ‐alanine:D ‐alanyl carrier protein ligase from Bacillus subtilis increases the bacterium's susceptibility to antibiotics that target the cell wall
2005
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis
2007
The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase
2000
Production of the Tubulin Destabilizer Disorazol in Sorangium cellulosum: Biosynthetic Machinery and Regulatory Genes
2005
Novel features in a combined polyketide synthase/non-ribosomal peptide synthetase: the myxalamid biosynthetic gene cluster of the myxobacterium Stigmatella aurantiaca Sga15
2001
Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death
2013 StandoutNobel
Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization
1999
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Structure and function of “metalloantibiotics”
2003
DNA‐Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules
2004 Standout
Cryptosporidium parvum: the first protist known to encode a putative polyketide synthase
2002
New Lessons for Combinatorial Biosynthesis from Myxobacteria
1999
Thioesterase domain of δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine synthetase: alteration of stereospecificity by site-directed mutagenesis
2000
Fungal secondary metabolism — from biochemistry to genomics
2005 Standout
The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90
2000
Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes
2001
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Ribozyme catalysis: not different, just worse
2005 StandoutNobel
Spiroketal Polyketide Formation in Sorangium: Identification and Analysis of the Biosynthetic Gene Cluster for the Highly Cytotoxic Spirangienes
2007
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
2006 Standout
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
A β‐lysine adenylating enzyme and a β‐lysine binding protein involved in poly β‐lysine chain assembly in nourseothricin synthesis in Streptomyces noursei
2002
Substrate Specificity of the Nonribosomal Peptide Synthetase PvdD fromPseudomonas aeruginosa
2003
EFFECTS OF BIODIVERSITY ON ECOSYSTEM FUNCTIONING: A CONSENSUS OF CURRENT KNOWLEDGE
2005 Standout
The evolution of gene collectives: How natural selection drives chemical innovation
2008
Ribosomal Synthesis of N-Methyl Peptides
2008 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Assembly-Line Enzymology for Polyketide and Nonribosomal Peptide Antibiotics: Logic, Machinery, and Mechanisms
2006
Phenylalanine Aminomutase-Catalyzed Addition of Ammonia to Substituted Cinnamic Acids: a Route to Enantiopure α- and β-Amino Acids
2009 StandoutNobel
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Non-Heme Fe(IV)–Oxo Intermediates
2007 Standout
Characterization of the Complete Zwittermicin A Biosynthesis Gene Cluster fromBacillus cereus
2008
Biosynthesis of Nonribosomal Peptides
2004
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Molecular Mechanisms Underlying Nonribosomal Peptide Synthesis: Approaches to New Antibiotics
2005
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
The complete genomic sequence of Nocardia farcinica IFM 10152
2004 Standout
A new and efficient multicomponent solid-phase synthesis of 2-acylaminomethylthiazoles
2003
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Biosynthetic Pathway and Gene Cluster Analysis of Curacin A, an Antitubulin Natural Product from the Tropical Marine Cyanobacterium Lyngbya majuscula
2004
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
Cloning and Heterologous Expression of the Epothilone Gene Cluster
2000 Science
Biochemical Properties and Crystal Structure of a β-Phenylalanine Aminotransferase from Variovorax paradoxus
2012 StandoutNobel
Siderophore-Based Iron Acquisition and Pathogen Control
2007 Standout
Antibiotics as Signal Molecules
2011
Learning from Nature's Drug Factories: Nonribosomal Synthesisof MacrocyclicPeptides
2003
Ulongamides A−F, New β-Amino Acid-Containing Cyclodepsipeptides from Palauan Collections of the Marine Cyanobacterium Lyngbya sp.
2002
Antitubercular Nucleosides That Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain
2006
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
A multifunctional polyketide–peptide synthetase essential for albicidin biosynthesis in Xanthomonas albilineans The GenBank accession number for the sequence determined in this work is AF239749.
2001
Resistance, resilience, and redundancy in microbial communities
2008 Standout
Chemoenzymatic and Template-Directed Synthesis of Bioactive Macrocyclic Peptides
2006
Polyketide and Nonribosomal Peptide Antibiotics: Modularity and Versatility
2004 Science
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Rationally Designed Nucleoside Antibiotics That Inhibit Siderophore Biosynthesis of Mycobacterium tuberculosis
2005
Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF, are induced by extracellular pyochelin in Pseudornonas aeruginosa
1998
Biochar effects on soil biota – A review
2011 Standout
Regulation of Bacterial Drug Export Systems
2002
Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis
1999 Science
Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes
2007
Genetics and Assembly Line Enzymology of Siderophore Biosynthesis in Bacteria
2002
Ribosomal Synthesis of Unnatural Peptides
2005 StandoutNobel
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Characterization of the angR Gene of Vibrio anguillarum : Essential Role in Virulence
1999
Synthetic Microcin C Analogs Targeting Different Aminoacyl-tRNA Synthetases
2009
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Works of Dirk Konz being referenced
How do peptide synthetases generate structural diversity?
1999
The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: molecular characterization of three multi-modular peptide synthetases
1997
Aminoacyl Adenylate Substrate Analogues for the Inhibition of Adenylation Domains of Nonribosomal Peptide Synthetases
2003
The two‐component regulatory system BacRS is associated with bacitracin ‘self‐resistance’ of Bacillus licheniformis ATCC 10716
2001
Characterization of a New Type of Phosphopantetheinyl Transferase for Fatty Acid and Siderophore Synthesis in Pseudomonas aeruginosa
2002
Molecular and Biochemical Characterization of the Protein Template Controlling Biosynthesis of the Lipopeptide Lichenysin
1999