Citation Impact
Citing Papers
Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo
2006
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)
1999 Standout
Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2
1999 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
HMGB1 in the Immunology of Sepsis (Not Septic Shock) and Arthritis
2004
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
2004 Standout
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
1995 Nature
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Lipoarabinomannans: from structure to biosynthesis
2003
Novel strategies for the treatment of sepsis
2003
Role of the bactericidal/permeability-increasing protein in host defence
1998
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Gram-negative Bacteria-binding Protein, a Pattern Recognition Receptor for Lipopolysaccharide and β-1,3-Glucan That Mediates the Signaling for the Induction of Innate Immune Genes in Drosophila melanogaster Cells
2000
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
2002
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
2003
Recognition of Pneumococcal Peptidoglycan
2003
TREM-1 amplifies inflammation and is a crucial mediator of septic shock
2001 StandoutNature
Recognition of endotoxin by cells leading to transmembrane signaling
1994
Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection
1997 Nature
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
Has the mortality of septic shock changed with time?
1998
A comparative analysis of cytokine production and tolerance induction by bacterial lipopeptides, lipopolysaccharides and Staphyloccocus aureus in human monocytes
1997
Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products
1999
Lipopolysaccharide (LPS) recognition in macrophages. Participation of LPS-binding protein and CD14 in LPS-induced adaptation in rabbit peritoneal exudate macrophages.
1993
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
1995
The immune response of Drosophila
2003 StandoutNatureNobel
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components
1999 Standout
Host innate immune responses to sepsis
2013
Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice
1995
CD14 Is a Cell-activating Receptor for Bacterial Peptidoglycan
1996
The Pathophysiology and Treatment of Sepsis
2003 Standout
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Roles of lipoarabinomannan in the pathogenesis of tuberculosis
1999
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells
1994 StandoutScience
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Localization of the binding site for the human high-affinity Fc receptor on IgG
1988 StandoutNatureNobel
The binding site for C1q on IgG
1988 StandoutNatureNobel
Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.
1997
Cancer-related inflammation
2008 StandoutNature
E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide
1999
Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients
2001
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine
2014 Standout
Staphylococcus aureusInfections
1998 Standout
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Human CD14 mediates recognition and phagocytosis of apoptotic cells
1998 Nature
Lipopolysaccharide‐binding protein mediates CD14‐independent intercalation of lipopolysaccharide into phospholipid membranes
1996
The plant immune system
2006 StandoutNature
The immunopathogenesis of sepsis
2002 StandoutNature
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
1993 StandoutNature
Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta.
1994
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.
1995
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
1996
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
1999 StandoutScience
Immunoglobulin G: Functional sites
1985
MIF mediation of sepsis
2000
Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes
1997
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Requirement for Croquemort in Phagocytosis of Apoptotic Cells in Drosophila
1999 Science
Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact
1997
A genome-wide analysis of immune responses in Drosophila
2001 StandoutNobel
Characterization of Early Cytokine Responses and an Interleukin (IL)-6–dependent Pathway of Endogenous Glucocorticoid Induction during Murine Cytomegalovirus Infection
1997
An opsonic function of the neutrophil bactericidal/permeability-increasing protein depends on both its N- and C-terminal domains
1997
Dual Activation of the Drosophila Toll Pathway by Two Pattern Recognition Receptors
2003 StandoutScienceNobel
Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B
1996
Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line
2001
Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway
1996
Correlation of histopathologic and bacteriologic changes with cytokine expression in an experimental murine model of bacteremic Staphylococcus aureus infection
1997
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Nuclear Translocation of NF-κB in Lipopolysaccharide-Treated Macrophages Fails To Correspond to Endotoxicity: Evidence Suggesting a Requirement for a Gamma Interferon-Like Signal
1998
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure.
1995 Nobel
Purification and molecular cloning of an inducible gram-negative bacteria-binding protein from the silkworm, Bombyx mori.
1996
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
IFN-γ Induces High Mobility Group Box 1 Protein Release Partly Through a TNF-Dependent Mechanism
2003
Reversing established sepsis with antagonists of endogenous high-mobility group box 1
2003
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
Treponema pallidumandBorrelia burgdorferiLipoproteins and Synthetic Lipopeptides Activate Monocytic Cells via a CD14-Dependent Pathway Distinct from That Used by Lipopolysaccharide
1998
Internalization of Staphylococcus aureus by endothelial cells induces cytokine gene expression
1995
A peptidoglycan recognition protein in innate immunity conserved from insects to humans
1998
Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow
2000 Science
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004 Standout
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
2007 StandoutNobel
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
LPS-binding proteins and receptors
1998
Regulation and Functional Involvement of Macrophage Scavenger Receptor MARCO in Clearance of Bacteria In Vivo
1999
Works of Didier Heumann being referenced
CD14 Is a pattern recognition receptor
1994
Bactericidal/Permeability-Increasing Protein Inhibits Induction of Macrophage Nitric Oxide Production by Lipopolysaccharide
1994
Digestion of Streptococcus pneumoniae Cell Walls with Its Major Peptidoglycan Hydrolase Releases Branched Stem Peptides Carrying Proinflammatory Activity
1999
High circulating levels of interleukin-6 in patients with septic shock: Evolution during sepsis, prognostic value, and interplay with other cytokines
1991
Antibodies to Core Lipopolysaccharide Determinants: Absence of Cross-reactivity with Heterologous Lipopolysaccharides
1991
Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations
1997
Competition between Bactericidal/Permeability-Increasing Protein and Lipopolysaccharide-Binding Protein for Lipopolysaccharide Binding to Monocytes
1993
Enhancement of murine macrophage binding of and response to bacterial lipopolysaccharide (LPS) by LPS-binding protein
1992
Pathogenesis and Potential Strategies for Prevention and Treatment of Septic Shock: An Update
1994
Lipopolysaccharide (LPS)-Binding Protein In Human Serum Determines The Tumor Necrosis Factor Response Of Monocytes To LPS
1994
Protection from septic shock by neutralization of macrophage migration inhibitory factor
2000
Distribution and properties of Fc receptors for IgG on different leucocyte populations in man.
1981
IFN-gamma involvement in the severity of gram-negative infections in mice.
1993
Mode of action of anti-lipopolysaccharide-binding protein antibodies for prevention of endotoxemic shock in mice.
1994
Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes
1992
Gram-positive cell walls stimulate synthesis of tumor necrosis factor alpha and interleukin-6 by human monocytes
1994
Contribution of TNF/TNF receptor and of Fas ligand to toxicity in murine models of endotoxemia and bacterial peritonitis.
1997
Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock.
1993
Postnatal development of the mouse cerebral neocortex. II. Quantitative cytoarchitectonics of visual and auditory areas.
1977
Short time exposure to lipopolysaccharide is sufficient to activate human monocytes.
1993
Interferon gamma receptor deficient mice are resistant to endotoxic shock.
1994
Cytokine production after intravenous or peritoneal gram-negative bacterial challenge in mice. Comparative protective efficacy of antibodies to tumor necrosis factor-alpha and to lipopolysaccharide.
1992
The Role of Lipopolysaccharide Binding Protein in Resistance to Salmonella Infections in Mice
2002