Citation Impact
Citing Papers
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
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Rising morbidity and mortality in midlife among white non-Hispanic Americans in the 21st century
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Role of Tetrodotoxin-Resistant Na+Current Slow Inactivation in Adaptation of Action Potential Firing in Small-Diameter Dorsal Root Ganglion Neurons
2003
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
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2013
Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain
2005
Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice
2014
High-Affinity Interaction of (des-Tyrosyl)Dynorphin A(2-17) with NMDA Receptors
1999
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2001
Adrenergic α2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice
1998 StandoutNobel
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2013
JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat
2008
Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat
2000
International Union of Pharmacology. XLIX. Nomenclature and Structure-Function Relationships of Transient Receptor Potential Channels
2005 StandoutNobel
p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia
2002
Emerging targets in neuroinflammation-driven chronic pain
2014
Knockdown of spinal metabotropic glutamate receptor 1 (mGluR1) alleviates pain and restores opioid efficacy after nerve injury in rats
2001
Decreases in endomorphin-2-like immunoreactivity concomitant with chronic pain after nerve injury
2001
Emerging drugs for osteoarthritis
2011
Novel class of pain drugs based on antagonism of NGF
2005
Antisense technologies
2003
Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory Neurons and Mediates Inflammatory Heat Hyperalgesia through TRPV1 Sensitization
2004
Effects of peripheral nerve injury on alpha-2A and alpha-2C adrenergic receptor immunoreactivity in the rat spinal cord
1999
Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels
2012
Knockdown of spinal opioid receptors by antisense targeting β-arrestin reduces morphine tolerance and allodynia in rat
2002
Intrathecal S-nitroso-N-acetylpenicillamine and l-cysteine attenuate nerve injury-induced allodynia through noradrenergic activation in rats
2000
Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis
2004
Descending control of pain
2002 Standout
Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats
2002
Adenosine in the spinal cord and periphery: release and regulation of pain
2003
Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain
2000
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2 R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
2008
Hyperexcitability in sensory neurons of rats selected for high versus low neuropathic pain phenotype
2001
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
Ion Channels in Analgesia Research
2007
Pro-resolving lipid mediators are leads for resolution physiology
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Aβ-fiber nociceptive primary afferent neurons: a review of incidence and properties in relation to other afferent A-fiber neurons in mammals
2004
Reduced Expression of A-Type Potassium Channels in Primary Sensory Neurons Induces Mechanical Hypersensitivity
2007
Mediation of spinal nerve injury induced tactile allodynia by descending facilitatory pathways in the dorsolateral funiculus in rats
2000
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons
2000
Guillain-Barré syndrome
2016 Standout
Downregulation of Transient Receptor Potential Melastatin 8 by Protein Kinase C-Mediated Dephosphorylation
2005
The effectiveness of spinal and systemic morphine on rat dorsal horn neuronal responses in the spinal nerve ligation model of neuropathic pain
1999
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
2007
The role of excitatory amino acid transmission within the rostral ventromedial medulla in the antinociceptive actions of systemically administered morphine
1999
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Cholecystokinin/opioid interactions
1999
Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections
2008 StandoutNobel
The antinociceptive effect of intrathecal administration of epibatidine with clonidine or neostigmine in the formalin test in rats
2001
Posttranslational mechanisms of peripheral sensitization
2004
A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone
1998
Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
2008 StandoutNobel
Opioid Therapy for Chronic Pain
2003
Morphine‐induced in vivo release of spinal cholecystokinin is mediated by δ‐opioid receptors – effect of peripheral axotomy
2001
Restriction of Transient Receptor Potential Vanilloid-1 to the Peptidergic Subset of Primary Afferent Neurons Follows Its Developmental Downregulation in Nonpeptidergic Neurons
2011 StandoutNobel
Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue
2001
Osteoarthritis
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Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology
2006 StandoutNobel
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Intrathecal implants of bovine chromaffin cells alleviate mechanical allodynia in a rat model of neuropathic pain
1998
Peripherally Administered alpha2-Adrenoceptor Agonist in the Modulation of Chronic Allodynia Induced by Spinal Nerve Ligation in the Rat
1997
In vivo silencing of the CaV3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy
2009
Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis
2013 StandoutNobel
Intrathecal Clonidine Alleviates Allodynia in Neuropathic Rats
1999
Increased level of cholecystokinin in cerebrospinal fluid is associated with chronic pain-like behavior in spinally injured rats
2001
The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats
2011
TRPA1 Contributes to Cold Hypersensitivity
2010 StandoutNobel
Artemin Overexpression in Skin Enhances Expression of TRPV1 and TRPA1 in Cutaneous Sensory Neurons and Leads to Behavioral Sensitivity to Heat and Cold
2006
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
2003 StandoutNature
Antagonists of the κ‐opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation
2003
Effect of α-adrenoceptor agents on imipramine-induced antinociception in nerve-ligated mice
2001
Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin
2001
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2009
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Analgesia Mediated by the TRPM8 Cold Receptor in Chronic Neuropathic Pain
2006
Endomorphin-1 and endomorphin-2: pharmacology of the selective endogenous μ-opioid receptor agonists
2000
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
The induction of pain: an integrative review
1999
Release of BDNF and GABA in the dorsal horn of neuropathic rats
2003
Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade
2015
De novo expression of Nav1.7 in injured putative proprioceptive afferents: Multiple tetrodotoxin-sensitive sodium channels are retained in the rat dorsal root after spinal nerve ligation
2014
Analgesic profile of intrathecal P2X3 antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats
2002
Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance
2003
Intravenous morphine does not modify dorsal horn touch-evoked allodynia in the mononeuropathic rat: a Fos study
2001
Role of Spinal NO in Antiallodynic Effect of Intrathecal Clonidine in Neuropathic Rats
1998
Spinal effect of a neuropeptide FF analogue on hyperalgesia and morphine‐induced analgesia in mononeuropathic and diabetic rats
1999
Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain
2005 StandoutNobel
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Acute tetrodotoxin‐induced neurotoxicity after ingestion of puffer fish
2005
Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain
1999
Caenorhabditis elegans TRPA-1 functions in mechanosensation
2007 StandoutNobel
Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
2006
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Spinal and Supraspinal Mechanisms of Neuropathic Pain
2000
Endogenous noradrenergic tone controls symptoms of allodynia in the spinal nerve ligation model of neuropathic pain
1999
The inflammatory reflex
2002 StandoutNature
Mechanisms of neuropathic pain
2011
In mononeuropathic rats, the enhancement of morphine antinociception by L-365,260, a selective CCKB receptor antagonist, depends on the dose of systemic morphine and stimulus characteristics
1997
A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain
2001
NMDA and opioid receptors: their interactions in antinociception, tolerance and neuroplasticity
1999
Moxonidine, a selective imidazoline/ α 2 adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice
2000
Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus
2002
P75-expressing elements are necessary for anti-allodynic effects of spinal clonidine and neostigmine
2001
Chronic pain and medullary descending facilitation
2002
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Neuropathic pain: aetiology, symptoms, mechanisms, and management
1999 Standout
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
2004 StandoutNobel
Intrathecal Drug Therapy for Chronic Pain
1999
Channeling pain
2006 StandoutNobel
Voltage-Gated Sodium Channels and Hyperalgesia
2004
Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone
1996
Redistribution of NaV1.8 in Uninjured Axons Enables Neuropathic Pain
2003
Dynorphin A Elicits an Increase in Intracellular Calcium in Cultured Neurons Via a Non-Opioid, Non-NMDA Mechanism
2000
Molecular Physiology of P2X Receptors
2002 Standout
Cell Signaling and the Genesis of Neuropathic Pain
2004
Roles of Tetrodotoxin (TTX)-Sensitive Na+Current, TTX-Resistant Na+Current, and Ca2+Current in the Action Potentials of Nociceptive Sensory Neurons
2002
Potentiation of Opioid Analgesia in Dopamine2Receptor Knock-Out Mice: Evidence for a Tonically Active Anti-Opioid System
2001
Altered Expression and Uptake Activity of Spinal Glutamate Transporters after Nerve Injury Contribute to the Pathogenesis of Neuropathic Pain in Rats
2003
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Sodium Channels in Normal and Pathological Pain
2010
Tonic Descending Facilitation from the Rostral Ventromedial Medulla Mediates Opioid-Induced Abnormal Pain and Antinociceptive Tolerance
2001
Enhanced Evoked Excitatory Transmitter Release in Experimental Neuropathy Requires Descending Facilitation
2003
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Upregulation of Dorsal Root Ganglion α2δ Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats
2001
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Neuropathic Pain Develops Normally in Mice Lacking both Nav1.7 and Nav1.8
2005
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Supraspinal contributions to hyperalgesia
1999
CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
2016 Standout
Beyond Neurons: Evidence That Immune and Glial Cells Contribute to Pathological Pain States
2002
Spinal Antinociceptive Synergism between Morphine and Clonidine Persists in Mice Made Acutely or Chronically Tolerant to Morphine
1999
Nodose Ganglia-Modulatory Effects on Respiration
2013
Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil
1999
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice
2002 StandoutNobel
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain
2006
Dynorphin Promotes Abnormal Pain and Spinal Opioid Antinociceptive Tolerance
2000
Osteoprotegerin diminishes advanced bone cancer pain.
2001
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
Circuitry Underlying Antiopioid Actions of Cholecystokinin Within the Rostral Ventromedial Medulla
2001
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Contribution of Nav1.8 Sodium Channels to Action Potential Electrogenesis in DRG Neurons
2001
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
2005
Inhibition of Neuropathic Pain by Selective Ablation of Brainstem Medullary Cells Expressing the μ-Opioid Receptor
2001
Pronociceptive Actions of Dynorphin Maintain Chronic Neuropathic Pain
2001
Time-Dependent Descending Facilitation from the Rostral Ventromedial Medulla Maintains, But Does Not Initiate, Neuropathic Pain
2002
Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?
2011
Mechanisms of Induction of Persistent Nociception by Dynorphin
2001
The α2aAdrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α2Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy
1997
Neurochemical and Cellular Reorganization of the Spinal Cord in a Murine Model of Bone Cancer Pain
1999
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Physiology of Microglia
2011 Standout
Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat
1999
Works of Di Bian being referenced
Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphine by antisera to dynorphin A (1–13) or MK-801 in a nerve-ligation model of peripheral neuropathy
1997
Inhibition by spinal morphine of the tail-flick response is attenuated in rats with nerve ligation injury
1995
Antibodies to Nerve Growth Factor Reverse Established Tactile Allodynia in Rodent Models of Neuropathic Pain without Tolerance
2007
Synergistic Antinociceptive Interactions of Morphine and Clonidine in Rats with Nerve-ligation Injury
1997
Tactile allodynia, but not thermal hyperalgesia, of the hindlimbs is blocked by spinal transection in rats with nerve injury
1998
Characterization of the antiallodynic efficacy of morphine in a model of neuropathic pain in rats
1995
Antiallodynic effects of a CCKB antagonist in rats with nerve ligation injury: role of endogenous enkephalins
1996
Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats
1999
Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats
1997
Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
2002
The loss of antinociceptive efficacy of spinal morphine in rats with nerve ligation injury is prevented by reducing spinal afferent drive
1995
Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum
1999
Spinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injury
1998
Characterization of Antiallodynic Actions of ALE-0540, a Novel Nerve Growth Factor Receptor Antagonist, in the Rat
1999
Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats
2000
A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain
1999
Regulation of morphine antiallodynic efficacy by cholecystokinin in a model of neuropathic pain in rats.
1995