Citation Impact

Citing Papers

Oxidative Stress
2017 Standout
Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1
2009
Transcriptional Regulation by Nrf2
2017 Standout
Functional analysis of human and chimpanzee promoters
2005 StandoutNobel
Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities
2021
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Function of alternative splicing
2004
Atopic Dermatitis
2008 Standout
Nuclear landscape of HIV-1 infection and integration
2016
Anti-inflammatory activity of natural dietary flavonoids
2010 Standout
The Retinal Pigment Epithelium in Visual Function
2005 Standout
Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication
2005
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
2017 StandoutNobel
Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols
2008
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
2007
Allosteric Inhibitor Development Targeting HIV‐1 Integrase
2011
Cancer to bone: a fatal attraction
2011 Standout
Lens epithelium-derived growth factor (LEDGF) delays photoreceptor degeneration in explants of rd/rd mouse retina
2001
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Histone methylation: a dynamic mark in health, disease and inheritance
2012 Standout
Regulation of the human thioredoxin gene promoter and its key substrates: A study of functional and putative regulatory elements
2013
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
The impact of thiol peroxidases on redox regulation
2015
Structure, mechanism and regulation of peroxiredoxins
2003 Standout
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Oxidative eustress: On constant alert for redox homeostasis
2021
Identification of an Allosteric Binding Site for Zn2+on the β2 Adrenergic Receptor
2002 StandoutNobel
Activation of peroxisome proliferator-activated receptor-γ (PPARγ) induces cell death through MAPK-dependent mechanism in osteoblastic cells
2006
Identification of PRDX6 as a regulator of ferroptosis
2019
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Peroxisome Proliferator-Activated Receptor γ Induces Pancreatic Cancer Cell Apoptosis
2001
A Review on the Dietary Flavonoid Kaempferol
2011 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Allosteric Modulation of β2-Adrenergic Receptor by Zn2+
2002 StandoutNobel
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Peroxisome proliferator‐activated receptor‐γ agonists prevent experimental autoimmune encephalomyelitis
2002
Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: Implications for systemic autoimmunity
2001
Transcriptional Regulation of Vascular Endothelial Growth Factor C by Oxidative and Thermal Stress Is Mediated by Lens Epithelium-Derived Growth Factor/p75
2009
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Autoimmunity and atopic dermatitis
2004
Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance
2012
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Retinitis pigmentosa
2006 Standout
Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes
2008
Peroxisome proliferator-activated receptor γ activators affect the maturation of human monocyte-derived dendritic cells
2001
Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
2009 Standout
Functional analysis of human promoter polymorphisms
2003
LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
2006
Oxidative Stress in Cancer
2020 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Metastasis to bone: causes, consequences and therapeutic opportunities
2002 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein
2002
Flavonoid composition of orange peel and its association with antioxidant and anti-inflammatory activities
2016 Standout
Identification and Characterization of the Chromatin-binding Domains of the HIV-1 Integrase Interactor LEDGF/p75
2006
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
2009
Oxidative stress response and Nrf2 signaling in aging
2015
Hepatoma-derived Growth Factor Is a Neurotrophic Factor Harbored in the Nucleus
2004
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Cooperative multi-modal sensing and therapeutic implications of the extracellular Ca2+ sensing receptor
2000
Cell death in health and disease
2007
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
HIF and the Lung
2011 StandoutNobel
Increased Sorbitol Pathway Activity Generates Oxidative Stress in Tissue Sites for Diabetic Complications
2005
The Reactive Species Interactome in the Brain
2021
Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling
2013
Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases
2012 Standout
Human Involucrin Promoter Mediates Repression-Resistant and Compartment-Specific LEKTI Expression
2011
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
2009 Standout
Molecular Mechanism of Hesperetin-7-O-glucuronide, the Main Circulating Metabolite of Hesperidin, Involved in Osteoblast Differentiation
2009
Transient and Stable Knockdown of the Integrase Cofactor LEDGF/p75 Reveals Its Role in the Replication Cycle of Human Immunodeficiency Virus
2006
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Prolonged Exposure to Free Fatty Acids Has Cytostatic and Pro-Apoptotic Effects on Human Pancreatic Islets
2002
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer
2007
Correction of the retinal dystrophy phenotype of the RCS rat by viral gene transfer of Mertk
2001
Fat and Beyond: The Diverse Biology of PPARγ
2008 Standout
Ca2+-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells
2001
LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes
2004
Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling
2016
Capturing Phase Behavior of Ternary Lipid Mixtures with a Refined Martini Coarse-Grained Force Field
2018
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
2005 Standout
Extracellular Calcium-Sensing Receptor Expression and Its Potential Role in Regulating Parathyroid Hormone-Related Peptide Secretion in Human Breast Cancer Cell Lines*
2000
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
2010 Standout
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
2015
Expression of extracellular calcium-sensing receptor in human osteoblastic MG-63 cell line
2001
Apoptosis in Human Oral Squamous Cell Carcinomas is Induced by 15-Deoxy-Δ12,14-Prostaglandin J2 but not by Troglitazone
2003
Deletion of Pten in Pancreatic β-Cells Protects Against Deficient β-Cell Mass and Function in Mouse Models of Type 2 Diabetes
2010 StandoutNobel
DAMPs, PAMPs and alarmins: all we need to know about danger
2006 Standout
Physiology of Microglia
2011 Standout
Extracellular Calcium Sensing and Extracellular Calcium Signaling
2001

Works of Dhirendra P. Singh being referenced

Lens epithelium-derived growth factor: increased resistance to thermal and oxidative stresses.
1999
Review: Age-Related Cataract: Immunity and Lens Epithelium-Derived Growth Factor (LEDGF)
2000
Loss of NF-κB Control and Repression of Prdx6 Gene Transcription by Reactive Oxygen Species-driven SMAD3-mediated Transforming Growth Factor β Signaling
2009
Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species
2017
Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation
2017
Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing
2000
Transcriptional Regulation of the Antioxidant Protein 2 Gene, a Thiol-specific Antioxidant, by Lens Epithelium-derived Growth Factor to Protect Cells from Oxidative Stress
2001
Specificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress
2011
Unraveling the role of membrane microdomains during microbial infections
2017
LEDGF Binds to Heat Shock and Stress-Related Element to Activate the Expression of Stress-Related Genes
2001
LEDGF, a survival factor, activates stress-related genes
2002
Activation of LEDGF Gene by Thermal- and Oxidative-Stresses
2000
Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells
2006
Development- and age-associated expression pattern of peroxiredoxin 6, and its regulation in murine ocular lens
2005
TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity
2008
Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells
2003
Peroxiredoxin 6 delivery attenuates TNF-α-and glutamate-induced retinal ganglion cell death by limiting ROS levels and maintaining Ca2+ homeostasis
2008
DNA Binding Domains and Nuclear Localization Signal of LEDGF: Contribution of two Helix-Turn-Helix (HTH)-like Domains and a Stretch of 58 Amino Acids of the N-terminal to the Trans-activation Potential of LEDGF
2005
Impaired homeostasis and phenotypic abnormalities in Prdx6−/−mice lens epithelial cells by reactive oxygen species: increased expression and activation of TGFβ
2005
Expression of peroxisome proliferator-activated receptors (PPARS) in human astrocytic cells: PPAR? agonists as inducers of apoptosis
2000
Lens Epithelium-Derived Growth Factor: Effects on Growth and Survival of Lens Epithelial Cells, Keratinocytes, and Fibroblasts
2000
Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus
2001
Transactivation of Involucrin, A Marker of Differentiation in Keratinocytes, by Lens Epithelium-Derived Growth Factor (LEDGF)
2002
Polyol pathway-dependent osmotic and oxidative stresses in aldose reductase-mediated apoptosis in human lens epithelial cells: role of AOP2
2004
Expression of Extracellular Calcium-Sensing Receptor by Human Lens Epithelial Cells
1997
PRDX6 attenuates oxidative stress- and TGFβ-induced abnormalities of human trabecular meshwork cells
2009
Neuroprotective effect of peroxiredoxin 6 against hypoxia-induced retinal ganglion cell damage
2010
Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6
2020
Delivery of a protein transduction domain-mediated Prdx6 protein ameliorates oxidative stress-induced injury in human and mouse neuronal cells
2015
Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats.
2001
Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis
2011
LEDGF: Survival of Embryonic Chick Retinal Photoreceptor Cells
2000
Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells
2019
Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure
2009
Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress
2018
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