Standout Papers
Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Disruption of Autophagy at the Maturation Step by the Carcinogen Lindane Is Associated with the Sustained Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Activity
2006
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Protein Phosphatase 2A (PP2A) Holoenzymes Regulate Death-associated Protein Kinase (DAPK) in Ceramide-induced Anoikis
2010
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions
2013
Autophagy and NF-κB: Fight for fate
2007
Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
2008
Autophagy in innate and adaptive immunity
2005
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
2012
Necroptosis and its role in inflammation
2015 StandoutNature
Pathogenesis of hepatitis B virus infection
2010
Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex
2007
Advances in molecular classification and precision oncology in hepatocellular carcinoma
2020
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Autophagy in human type 2 diabetes pancreatic beta cells
2009
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
2006 Standout
Autophagy regulates lipid metabolism
2009 StandoutNature
Molecular viral oncology of hepatocellular carcinoma
2003
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
2006 Standout
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Loss of Macroautophagy Promotes or Prevents Fibroblast Apoptosis Depending on the Death Stimulus
2007
The Autophagy Protein Atg12 Associates with Antiapoptotic Bcl-2 Family Members to Promote Mitochondrial Apoptosis
2011
Hepatocellular carcinoma
2021 Standout
Death by design: apoptosis, necrosis and autophagy
2004
WIPI-1α (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy
2004
Essential Roles of Atg5 and FADD in Autophagic Cell Death
2005
Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
2005
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
2007
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Decoding ALS: from genes to mechanism
2016 StandoutNature
The pleiotropic role of autophagy: from protein metabolism to bactericide
2005
Network organization of the human autophagy system
2010 StandoutNature
Autophagy Signaling and the Cogwheels of Cancer
2006
Autophagy delays apoptotic death in breast cancer cells following DNA damage
2006
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
2011 StandoutNature
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
2007
The Atg12-Atg5 Conjugate Has a Novel E3-like Activity for Protein Lipidation in Autophagy
2007 StandoutNobel
Viral interactions with macroautophagy: A double-edged sword
2010
Autophagy in the Pathogenesis of Disease
2008 Standout
The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras
2009
Autophagy in metazoans: cell survival in the land of plenty
2005
Autophagy: from phenomenology to molecular understanding in less than a decade
2007 Standout
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study
2005
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
2005 Standout
Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1
2007
Down‐regulation of Bax‐interacting factor‐1 in colorectal adenocarcinoma
2008
Regulation of Autophagy by Sphingosine Kinase 1 and Its Role in Cell Survival during Nutrient Starvation
2006
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
2007
Does autophagy have a license to kill mammalian cells?
2008
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
2015
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
2001
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Origin and physiological roles of inflammation
2008 StandoutNature
ROS, mitochondria and the regulation of autophagy
2007
Inactivation of the Autophagy Gene bec-1 Triggers Apoptotic Cell Death in C. elegans
2005
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
2006
Anti- and pro-tumor functions of autophagy
2009
Autophagy and Human Disease
2007
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
DAP‐kinase‐mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl‐XL and induction of autophagy
2009
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
Autophagy in cell death: an innocent convict?
2005 Standout
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Autophagic pathways as new targets for cancer drug development
2010
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS–p38–p53 pathway
2008
DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions
2012
The Hallmarks of Aging
2013 Standout
The Pancreatitis-induced Vacuole Membrane Protein 1 Triggers Autophagy in Mammalian Cells
2007
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
2015
PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk
2011
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
2005
Selective degradation of mitochondria by mitophagy
2007
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
2007
The role of autophagy in cancer development and response to therapy
2005
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
2006
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
2014
Autophagy in immunity and inflammation
2011 StandoutNature
Crosstalk between apoptosis, necrosis and autophagy
2013
The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinase
2010
The autophagy effector Beclin 1: a novel BH3-only protein
2008
Organelle-specific initiation of cell death pathways
2001
Autophagy and cancer
2007 Nature
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Insulin‐like growth factor‐1 and TNF‐α regulate autophagy through c‐jun N‐terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
2006
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Micrometastatic Disease and Metastatic Outgrowth: Clinical Issues and Experimental Approaches
2009
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Genome-wide comprehensive analysis of human helicases
2011
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
2007
BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy
2007
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
2005
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
2005 Standout
Selective Inactivation of a Fas-associated Death Domain Protein (FADD)-dependent Apoptosis and Autophagy Pathway in Immortal Epithelial Cells
2005
The molecular machinery of autophagy: unanswered questions
2004
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
2010
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Structural diversity of calmodulin binding to its target sites
2013
Genome-wide comprehensive analysis of human helicases.
2011
Autophagy Is Induced in CD4+ T Cells and Important for the Growth Factor-Withdrawal Cell Death
2006
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Autophagy: Basic Principles and Relevance to Disease
2008
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Devrim Gözüaçık being referenced
Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging
2001
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death
2008
Autophagy as a cell death and tumor suppressor mechanism
2004 Standout
Identification and functional characterization of a new member of the human Mcm protein family: hMcm8
2003
Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)
2000
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene
2003
DAPk Protein Family and Cancer
2006
Autophagy and Cell Death
2007
Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death
2012
The dependence receptor UNC5H2 mediates apoptosis through DAP‐kinase
2005
Serca1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis
2001
Death-Associated Protein Kinase Phosphorylates ZIP Kinase, Forming a Unique Kinase Hierarchy To Activate Its Cell Death Functions
2004