Citation Impact
Citing Papers
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
Purification and Characterization of Recombinant Cystic Fibrosis Transmembrane Conductance Regulator from Chinese Hamster Ovary and Insect Cells
1995
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)
1992
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical manifestations of cystic fibrosis.
1992
Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation
1991 Nature
Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I
1992 Nature
Gene therapy for cystic fibrosis: challenges and future directions.
1995
Generation and characterization of a ΔF508 cystic fibrosis mouse model
1995 StandoutNobel
Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin
1991
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Effects of the ?F508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR
1993
Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II
1993 Nature
ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes
1997
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms
2004
Activation by Extracellular Nucleotides of Chloride Secretion in the Airway Epithelia of Patients with Cystic Fibrosis
1991
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Potassium channels and their evolving gates
1994 Nature
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
1992
Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR
1992 Nature
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Dual role of calmodulin in autophosphorylation of multifunctional cam kinase may underlie decoding of calcium signals
1994
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
1992 Nature
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Cloning and expression of an inwardly rectifying ATP-regulated potassium channel
1993 Nature
Production of a severe cystic fibrosis mutation in mice by gene targeting
1993 StandoutNobel
Structural Basis of Inward Rectification
2002 StandoutNobel
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
1994 StandoutNatureNobel
Identification and regulation of the cystic fibrosis transmembrane conductance regulator-generated chloride channel.
1991
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA
1993
Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting
1992 StandoutNobel
A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation
2011 Standout
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel
1994 StandoutNatureNobel
CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP
1995 StandoutNobel
Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms
1997 Nature
Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase
1991 StandoutNobel
Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland
1992
The cystic fibrosis mutation (ΔF508) does not influence the chloride channel activity of CFTR
1993
Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells
1992
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung afterin vivointratracheal plasmid-mediated gene transfer
1992
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
In vivo cell-specific expression of the cystic fibrosis transmembrane conductance regulator
1991 Nature
Activation of multifunctional Ca2+/calmodulin-dependent kinase in intact hippocampal slices
1991
Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.
1991
Quantitative expression patterns of multidrug‐resistance P‐glycoprotein (MDR1) and differentially spliced cystic‐fibrosis transmembrane‐conductance regulator mRNA transcripts in human epithelia
1992
The Two Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Have Distinct Functions in Controlling Channel Activity
1995
Sensory Nerves in Lung and Airways
2014
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
1992
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
1990 Standout
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
1996 StandoutNobel
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
1991
CFTR: Development of high- affinity antibodies and localization in sweat gland
1991
Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
1993
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal ltp in the range of the θ frequency
1995 StandoutNobel
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons
1993 StandoutNobel
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens
1995 Standout
The spectrum of cystic fibrosis mutations
1992
A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans
1994 Nature
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
1995 Standout
Molecular and Structural Basis of Target Recognition by Calmodulin
1995
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene
1991 Nature
Multifunctional calcium/calmodulin-dependent protein kinase made calcium-independent for functional studies
1990
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Cloning the mouse homolog of the human cystic fibrosis transmembrane conductance regulator gene
1991
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Ion-transporting activity in the murine colonic epithelium of normal animals and animals with cystic fibrosis
1994 StandoutNobel
Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type Cftr gene expression
1994
The Cystic Fibrosis Transmembrane Conductance Regulator Gene
1995
Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents.
1992
An Animal Model for Cystic Fibrosis Made by Gene Targeting
1992 StandoutScienceNobel
Chloride secretory response to extracellular ATP in human normal and cystic fibrosis nasal epithelia
1992
An Adenovirus Type 5 (Ad5) Amplicon-Based Packaging Cell Line for Production of High-Capacity Helper-Independent ΔE1-E2-E3-E4 Ad5 Vectors
2005
Regulation of Plasma Membrane Recycling by CFTR
1992 Science
Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes
1991 Science
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons
1993 StandoutScienceNobel
Is congenital bilateral absence of vas deferens a primary form of cystic fibrosis? Analyses of the CFTR gene in 67 patients.
1995
Autophosphorylation of type II Ca2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slices.
1991
Studies of the Regulatory Mechanism of Ca2+/Calmodulin-dependent protein kinase II
1989
Defective Epithelial Chloride Transport in a Gene-Targeted Mouse Model of Cystic Fibrosis
1992 StandoutScienceNobel
Biochemical characterization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis epithelial cells.
1992
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.
1993
Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity
1991 Science
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse
1994
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Distinct autophosphorylation sites sequentially produce autonomy and inhibition of the multifunctional Ca2+/calmodulin-dependent protein kinase
1989
Forskolin Stimulation of Water and Cation Permeability in Aquaporin1 Water Channels
1996 Science
Cystic Fibrosis Gene Mutation in Two Sisters with Mild Disease and Normal Sweat Electrolyte Levels
1991
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin- dependent protein kinase II and protein kinase C in cultured hippocampal neurons
1994
Molecular Structure and Physiological Function of Chloride Channels
2002
Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice
1992 ScienceNobel
Chloride secretion in the trachea of null cystic fibrosis mice: the effects of transfection with pTrial10‐CFTR2.
1997 StandoutNobel
Nanoscale Atoms in Solid-State Chemistry
2013 StandoutScienceNobel
Cystic ibrosis: Molecular Biology and Therapeutic Implications
1992 Science
A mutation in CFTR produces different phenotypes depending on chromosomal background
1993
The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression.
1992
Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene.
1991
Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium.
1991
Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro.
1994
CREB: a Ca 2+ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases
1991 Science
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Are Adult Learning Mechanisms Also Used for Development?
1992 StandoutScienceNobel
Discrete Fulleride Anions and Fullerenium Cations
2000
Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.
1991
CFTR protein expression in primary and cultured epithelia.
1992
Correlation between Genotype and Phenotype in Patients with Cystic Fibrosis
1993
Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.
1994
Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum.
1995
Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.
1992
Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP.
1992
Revealing the Architecture of a K + Channel Pore Through Mutant Cycles with a Peptide Inhibitor
1995 StandoutScienceNobel
Hyperabsorption of Na+ and raised Ca(2+)-mediated Cl- secretion in nasal epithelia of CF mice
1994
Ripped Pocket and Pickpocket, Novel Drosophila DEG/ENaC Subunits Expressed in Early Development and in Mechanosensory Neurons
1998
ABC Transporters: From Microorganisms to Man
1992 Standout
Immunocytochemical localization of the cystic fibrosis gene product CFTR.
1991
Aerosol gene delivery in vivo.
1992
Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia.
1991
Alternate pathways for chloride conductance activation in normal and cystic fibrosis airway epithelial cells
1992
Genetic determination of exocrine pancreatic function in cystic fibrosis.
1992
Sequence analysis and DNA-protein interactions within the 5' flanking region of the Ca2+/calmodulin-dependent protein kinase II alpha-subunit gene.
1990
Production and characterisation of monoclonal and polyclonal antibodies to different regions of the cystic fibrosis transmembrane conductance regulator (cftr): Detection of immunologically related proteins
1995
Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II.
1993
cAMP-inducible chloride conductance in mouse fibroblast lines stably expressing the human cystic fibrosis transmembrane conductance regulator.
1991
Works of Devra P. Rich being referenced
The amino-terminal portion of CFTR forms a regulated CI− channel
1994
Expression and characterization of the cystic fibrosis transmembrane conductance regulator
1990 Nature
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
1991
Nucleoside triphosphates are required to open the CFTR chloride channel
1991
Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties
1993 Nature
Development and Analysis of Recombinant Adenoviruses for Gene Therapy of Cystic Fibrosis
1993
Cystic fibrosis transmembrane conductance regulator splice variants are not conserved and fail to produce chloride channels
1993
Identification of revertants for the cystic fibrosis ΔF508 mutation using STE6-CFTR chimeras in yeast
1993
Regulatory Properties of Calcium/Calmodulin‐Dependent Protein Kinase II in Rat Brain Postsynaptic Densities
1989
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
1990 Nature
Cystic fibrosis transmembrane conductance regulator: A chloride channel with novel regulation
1992
Cystic Fibrosis Gene Therapy Using an Adenovirus Vector: In Vivo Safety and Efficacy in Nasal Epithelium. Howard Hughes Medical Institute, Iowa City, IA
1994
Generation of the Ca2+-independent form of Ca2+/calmodulin-dependent protein kinase II in cerebellar granule cells
1989
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel
1991
Maturation and Function of Cystic Fibrosis Transmembrane Conductance Regulator Variants Bearing Mutations in Putative Nucleotide-Binding Domains 1 and 2
1991
Generation of cAMP-Activated Chloride Currents by Expression of CFTR
1991 Science
Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem
1989
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
1993
Effect of deletion mutations on the function of CFTR chloride channels.
1993
Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2.
1991
Effect of Deleting the R Domain on CFTR-Generated Chloride Channels
1991 Science