Citation Impact
Citing Papers
Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity
2011
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
2017 StandoutNobel
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Oxygen toxicity causes cyclic damage by destabilizing specific Fe-S cluster-containing protein complexes
2023
Current knowledge on exosome biogenesis and release
2017 Standout
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin
2013
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
2014 Standout
Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages
2012
Autophagy in infection, inflammation and immunity
2013 Standout
NF-κB signaling in inflammation
2017 Standout
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Necroptosis and its role in inflammation
2015 StandoutNature
Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity
2012
Bacterial Exotoxins and the Inflammasome
2015
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Activation and regulation of the inflammasomes
2013 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
2012 Standout
Mechanisms of inflammasome activation: recent advances and novel insights
2015
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor
2013
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration
2018
Inflammasomes in Intestinal Inflammation and Cancer
2011
Regulation of inflammasome signaling
2012
Caspase-1 Dependent IL-1β Secretion Is Critical for Host Defense in a Mouse Model of Chlamydia pneumoniae Lung Infection
2011
Endocytosis of the Anthrax Toxin Is Mediated by Clathrin, Actin and Unconventional Adaptors
2010
The Inflammasomes: Molecular Effectors of Host Resistance Against Bacterial, Viral, Parasitic, and Fungal Infections
2011
Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
2012
Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation
2014
A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome
2018
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Multidimensional Profiling in the Investigation of Small-Molecule-Induced Cell Death
2014
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors
2013
NLRP3 Inflammasome Activation Induced by Engineered Nanomaterials
2012
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
2011 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells
2014 Nature
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
Macrophage M1/M2 polarization
2020 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
2013
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
Gasdermins: Effectors of Pyroptosis
2017 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
2015 Standout
Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
2015 Standout
IFITM3 directly engages and shuttles incoming virus particles to lysosomes
2018 StandoutNobel
Inflammasomes and Metabolic Disorders: Old Genes in Modern Diseases
2014
Control of adaptive immunity by the innate immune system
2015 Standout
Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation
2018
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
The Cyclopentenone Prostaglandin 15d-PGJ2 Inhibits the NLRP1 and NLRP3 Inflammasomes
2015
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
Chemical Strategies To Target Bacterial Virulence
2017
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Structural characterization of ribosome recruitment and translocation by type IV IRES
2016 Nobel
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
2011
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Caspase-11 Modulates Inflammation and AttenuatesToxoplasma gondiiPathogenesis
2016
Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation
2016
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Pyroptotic cell death defends against intracellular pathogens
2015
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A
2016 StandoutNobel
Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism
2015
Immunogenicity of therapeutic recombinant immunotoxins
2016
Phosphatidylglycerol::Prolipoprotein Diacylglyceryl Transferase (Lgt) of Escherichia coli Has Seven Transmembrane Segments, and Its Essential Residues Are Embedded in the Membrane
2012
NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii
2013
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The NLRP 1 inflammasomes
2015
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
2016
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
Cutting Edge: Resistance to Bacillus anthracis Infection Mediated by a Lethal Toxin Sensitive Allele of Nalp1b/Nlrp1b
2009
Recognition of Bacteria by Inflammasomes
2012
Large-scale determination of previously unsolved protein structures using evolutionary information
2015 StandoutNobel
Reassessing the Evolutionary Importance of Inflammasomes
2016
Regulation of inflammasome activation
2015
The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
2016
Works of Devorah Crown being referenced
Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo
2009
Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo
2015
Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages
2010
Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice
2010
Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain
2012
The Bacillus cereus Hbl and Nhe Tripartite Enterotoxin Components Assemble Sequentially on the Surface of Target Cells and Are Not Interchangeable
2013
Key tissue targets responsible for anthrax-toxin-induced lethality
2013 Nature
Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii
2014
Transcriptional analysis of the three Nlrp1 paralogs in mice
2013
Lipoprotein biosynthesis by prolipoprotein diacylglyceryl transferase is required for efficient spore germination and full virulence of Bacillus anthracis
2011
Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment
2010
Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor
2008
Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1
2010
Antidotes to anthrax lethal factor intoxication. Part 2: Structural modifications leading to improved in vivo efficacy
2011
Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity
2018
Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii
2014
Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development
2012
Arsenic Trioxide and Other Arsenical Compounds Inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 Inflammasomes
2013
Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection
2011
Small-Molecule Inhibitors of Lethal Factor Protease Activity Protect against Anthrax Infection
2013