Citation Impact
Citing Papers
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 Standout
Oxidative Stress
2017 Standout
Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis
2017
Interstitial Cells: Regulators of Smooth Muscle Function
2014
Nrf2 and Keap1 Abnormalities in Non–Small Cell Lung Carcinoma and Association with Clinicopathologic Features
2010
Nrf2 Prevents Initiation but Accelerates Progression through the Kras Signaling Pathway during Lung Carcinogenesis
2013
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Transcriptional Regulation by Nrf2
2017 Standout
Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
2012
NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
2009 Standout
Identification of the primary caspase 3 cleavage site in alpha II-spectrin during apoptosis
2003
Glutathione: new roles in redox signaling for an old antioxidant
2014
Nrf2: friend or foe for chemoprevention?
2009
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
2012 Standout
Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer
2013
Methylation of the KEAP1 gene promoter region in human colorectal cancer
2012
Bowel Disorders
2016 Standout
Role of Nrf2 and Autophagy in Acute Lung Injury
2016
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
Role of T cells, cytokines and antibody in dengue fever and dengue haemorrhagic fever
2006
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
NRF2 and cancer: the good, the bad and the importance of context
2012
Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405
2015
From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
2017
Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
2012
The Keap1–Nrf2 system as an in vivo sensor for electrophiles
2011
Immunolocalization of the gap junction protein Connexin43 in the interstitial cells of Cajal in the normal and Hirschsprung's disease bowel
2000
An Antioxidant Response Phenotype Shared between Hereditary and Sporadic Type 2 Papillary Renal Cell Carcinoma
2011
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Nrf2 protects against airway disorders
2009
Growth differentiation factor-5–gelatin methacryloyl injectable microspheres laden with adipose-derived stem cells for repair of disc degeneration
2020
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
2016 Standout
The KEAP1–NRF2 System in Cancer
2017
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
2019 StandoutNobel
The emerging role of the Nrf2–Keap1 signaling pathway in cancer
2013
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways
2012 StandoutNobel
Heterogeneous distribution of a gap junction protein, connexin43, in the gastroduodenal junction of the guinea pig
2001
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation
2016
The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
2012
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway
2017
Promoter demethylation of Keap1 gene in human diabetic cataractous lenses
2012
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Dual roles of Nrf2 in cancer
2008
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin
2009
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Targeting NRF2 signaling for cancer chemoprevention
2009
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
2005 Standout
Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice
2010
Monitoring Keap1–Nrf2 interactions in single live cells
2014
Oxidative Stress in Cancer
2020 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Molecular Basis of Electrophilic and Oxidative Defense: Promises and Perils of Nrf2
2012
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
2012 Standout
AberrantKeap1methylation in breast cancer and association with clinicopathological features
2012
A cytoprotective perspective on longevity regulation
2013 StandoutNobel
Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance
2015
Interstitial cells of Cajal in the deep muscular plexus mediate enteric motor neurotransmission in the mouse small intestine
2006
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Structure of the Calmodulin αII-Spectrin Complex Provides Insight into the Regulation of Cell Plasticity
2006 StandoutNobel
Targeting Nrf2-Keap1 signaling for chemoprevention of skin carcinogenesis with bioactive phytochemicals
2014
Targeted Deletion of Nrf2 Reduces Urethane-Induced Lung Tumor Development in Mice
2011
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Frequent epigenetics inactivation of KEAP1 gene in non-small cell lung cancer
2011
Dengue Virus Infects Macrophages and Dendritic Cells in a Mouse Model of Infection
2007
Cellular mechanisms and physiological consequences of redox-dependent signalling
2014 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms
2011
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
2011
Nrf2 activation improves experimental rheumatoid arthritis
2023 StandoutNobel
Dengue
2007 Standout
Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells
2021
Nrf2, the Master Regulator of Anti-Oxidative Responses
2017
Accumulation of phosphorylated p62 is associated with NF-E2-related factor 2 activation in hepatocellular carcinoma
2016
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
Capturing Magnesium Ions via Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration
2021 Standout
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Fundamentals of cancer metabolism
2016 Standout
Accumulation of p62/SQSTM 1 is associated with poor prognosis in patients with lung adenocarcinoma
2012
Genomic Structure and Variation of Nuclear Factor (Erythroid-Derived 2)-Like 2
2013
The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment
2020
Metabolic Regulation of Redox Balance in Cancer
2019
Macrophages in the external muscle layers of mammalian intestines.
1995
Hypoxia Induces Myocardial Regeneration in Zebrafish
2012
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Regulation ofKEAP1expression by promoter methylation in malignant gliomas and association with patient’s outcome
2011
SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
2011 Standout
Life cycle of connexins in health and disease
2006 Standout
The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer
2017
Regulation of cell proliferation by hypoxia-inducible factors
2015 StandoutNobel
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
Works of Deshan Zhou being referenced
Cytoskeletal Disruption Accelerates Caspase-3 Activation and Alters the Intracellular Membrane Reorganization in DNA Damage-Induced Apoptosis
2000
An age-dependent proliferation is involved in the postnatal development of interstitial cells of Cajal in the small intestine of mice
2008
The cellular network of interstitial cells associated with the deep muscular plexus of the guinea pig small intestine
1992
Immunohistochemical study of the c-kit expressing cells and connexin 43 in the guinea-pig digestive tract
1998
Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues
2008
Distribution and possible role of PDGF-AA and PDGFR-α in the gastrointestinal tract of adult guinea pigs
2010
Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells
2012
A possible gene silencing mechanism: Hypermethylation of the Keap1 promoter abrogates binding of the transcription factor Sp1 in lung cancer cells
2012
Resveratrol protects human keratinocytes HaCaT cells from UVA-induced oxidative stress damage by downregulating Keap1 expression
2010
Interstitial cells associated with the deep muscular plexus of the guinea-pig small intestine, with special reference to the interstitial cells of Cajal
1992
Inhibitory effects of glutathione on dengue virus production
2010
Dengue-specific CD8+ T cells have both protective and pathogenic roles in dengue virus infection
2004
Plasticity of Interstitial Cells of Cajal: A Study in the Small Intestine of Adult Guinea Pigs
2009
JAK—STAT signaling pathway in pulmonary arterial smooth muscle cells is activated by hypoxia
2005
Effects of releasing recombinant human growth and differentiation factor-5 from poly(lactic-co-glycolic acid) microspheres for repair of the rat degenerated intervertebral disc
2013