Citation Impact
Citing Papers
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses
2011
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Cancer Cell Secretion of the DAMP Protein HMGB1 Supports Progression in Malignant Mesothelioma
2012
Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia
2010
Extracellular HMGB1 as a Proinflammatory Cytokine
2004
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
HMGB1 in the Immunology of Sepsis (Not Septic Shock) and Arthritis
2004
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
Deoxycholate induces mitochondrial oxidative stress and activates NF- B through multiple mechanisms in HCT-116 colon epithelial cells
2006
Genetic effects on gene expression across human tissues
2017 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
A High-throughput Quantitative Multiplex Kinase Assay for Monitoring Information Flow in Signaling Networks
2003
Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation
2009
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Clearance of apoptotic and necrotic cells and its immunological consequences
2006
Alarmins: awaiting a clinical response
2012
The biology of RAGE and its ligands: Uncovering mechanisms at the heart of diabetes and its complications
2007
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Cell death, BAX activation, and HMGB1 release during infection with Chlamydia
2004
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
2007
Monocytes promote natural killer cell interferon gamma production in response to the endogenous danger signal HMGB1
2004
Inflammation and Lipid Signaling in the Etiology of Insulin Resistance
2012
Neutrophils in development of multiple organ failure in sepsis
2006
Innate immunity conferred by toll‐like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal–induced inflammation
2005
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Toll-like receptors and cancer
2008
Pattern Recognition Receptors and Inflammation
2010 Standout
NLRs join TLRs as innate sensors of pathogens
2005
Insights into G Protein Structure, Function, and Regulation
2003
TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation
2011
Toll-like receptors in systemic autoimmune disease
2006
NF-κB activation by reactive oxygen species: Fifteen years later
2006
Innate immune signaling in cardiac ischemia
2011
HMGB1, a Novel Cytokine-Like Mediator Linking Acute Neuronal Death and Delayed Neuroinflammation in the Postischemic Brain
2006
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Extracellular role of HMGB1 in inflammation and sepsis
2004
Effective clearance of intracellular Leishmania majorin vivo requires Pten in macrophages
2008 StandoutNobel
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Macrophage activation by endogenous danger signals
2007
Mechanisms of sepsis-induced organ dysfunction
2007
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Functional roles for C5a receptors in sepsis
2008
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
2007
Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function
2004
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
RAGE (receptor for advanced glycation end products): a central player in the inflammatory response
2004
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
2009 Standout
Neurodegeneration and Inflammation
2008
How dying cells alert the immune system to danger
2008
Immunity, Inflammation, and Cancer
2010 Standout
RAGE is the Major Receptor for the Proinflammatory Activity of HMGB1 in Rodent Macrophages
2005
Inflammation and necrosis promote tumour growth
2004
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
A calculated response: control of inflammation by the innate immune system
2008
Host innate immune responses to sepsis
2013
High mobility group box 1 protein, a cue for stem cell recruitment
2004
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction
2013
Origin and physiological roles of inflammation
2008 StandoutNature
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Cancer Immunotherapy by Dendritic Cells
2008
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
2005 Standout
Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury
2006
Differential Significance of Plasma Visfatin Concentrations according to Adiposity in Children and Adolescents
2013 Standout
Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling
2008
Toll‐like receptor 4 contributes to poor outcome after intracerebral hemorrhage
2011 StandoutNobel
Cellular signalling of the receptor for advanced glycation end products (RAGE)
2013
Harmful molecular mechanisms in sepsis
2008
Toll‐like receptors, endogenous ligands, and systemic autoimmune disease
2005
Characterization of Heme as Activator of Toll-like Receptor 4
2007
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Cancer-related inflammation
2008 StandoutNature
Necrosis is associated with IL-6 production but apoptosis is not
2005
Toll-like receptors in inflammatory bowel diseases: A decade later
2010
The innate immune response in reperfused myocardium
2012
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Exploring the full spectrum of macrophage activation
2008 Standout
Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects
2003
Pathogen Recognition and Innate Immunity
2006 Standout
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Immunogenic death of colon cancer cells treated with oxaliplatin
2009
Inflammasomes in health and disease
2012 StandoutNature
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
HMGB1 is an endogenous immune adjuvant released by necrotic cells
2004
Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways
2010
The extra domain A of fibronectin stimulates murine mast cells via Toll-like receptor 4
2007
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization
2004
HMGB1 Develops Enhanced Proinflammatory Activity by Binding to Cytokines
2008
The role of chemokines and chemokine receptors in pulmonary arterial hypertension
2019
Immunologically Active Autoantigens: The Role of Toll-Like Receptors in the Development of Chronic Inflammatory Disease
2007
Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response
2011
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart
2008
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
The role of TLR4 in the pathogenesis of indirect acute lung injury
2013
The Roles of Therapy-Induced Autophagy and Necrosis in Cancer Treatment
2007
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.
1996 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Hyaluronan in Tissue Injury and Repair
2007
Plasma High-Mobility Group Box 1 Levels Predict Mortality After ST-Segment Elevation Myocardial Infarction
2011
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization.
1994
The Inflammatory Response to Cell Death
2008
Danger Signals in the Initiation of the Inflammatory Response after Myocardial Infarction
2013
uPA deficiency exacerbates muscular dystrophy in MDX mice
2007
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
2005
HMGB1: Endogenous Danger Signaling
2008
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms
2004
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
High mobility group box 1 protein as a late-acting mediator of acute lung inflammation.
2004
DAMPs, PAMPs and alarmins: all we need to know about danger
2006 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Toll-Like Receptors 2-Deficient Mice Are Protected Against Postischemic Coronary Endothelial Dysfunction
2007
Works of Derek Strassheim being referenced
Sustained hypoxia leads to the emergence of cells with enhanced growth, migratory, and promitogenic potentials within the distal pulmonary artery wall
2009
Emergence of Fibroblasts with a Proinflammatory Epigenetically Altered Phenotype in Severe Hypoxic Pulmonary Hypertension
2011
Phosphoinositide 3-Kinase and Akt Occupy Central Roles in Inflammatory Responses of Toll-Like Receptor 2-Stimulated Neutrophils
2004
Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
2004
HMGB1 contributes to the development of acute lung injury after hemorrhage
2005
Sepsis: current concepts in intracellular signaling
2002
High mobility group box 1 protein interacts with multiple Toll-like receptors
2005
Involvement of PKCα/β in TLR4 and TLR2 dependent activation of NF-κB
2004
Urokinase-Type Plasminogen Activator Potentiates Lipopolysaccharide-Induced Neutrophil Activation
2003
Activation of gene expression in human neutrophils by high mobility group box 1 protein
2003
Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB
2004
B Cell Subsets Contribute to Renal Injury and Renal Protection after Ischemia/Reperfusion
2010
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
1994