Citation Impact
Citing Papers
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Direct Evidence That Functionally Impaired CD4+ T Cells Persist In Vivo Following Induction of Peripheral Tolerance
1998
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
2001
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
Establishment of a tissue-specific RNAi system in C. elegans
2007
Characterization of skn-1/wdr-23 phenotypes in Caenorhabditis elegans; pleiotrophy, aging, glutathione, and interactions with other longevity pathways
2015
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
The immunology of susceptibility and resistance to Leishmania major in mice
2002 Standout
Enhanced neuronal RNAi in C. elegans using SID-1
2010 Nobel
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Antagonistic Regulation of Synaptic Vesicle Priming by Tomosyn and UNC-13
2006
Complexin Has Opposite Effects on Two Modes of Synaptic Vesicle Fusion
2011
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
T-cell and cytokine responses in leishmaniasis
1993
Structure and function of SNARE and SNARE-interacting proteins
2005
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans
2015
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: Nicotinic acetylcholine receptors, a case study
2006
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting
2002
Cytokines in the treatment of leishmaniasis: From studies of immunopathology to patient therapy
1994
Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
2015 Nature
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
WDR23 regulates NRF2 independently of KEAP1
2017
Food Sensation Modulates Locomotion by Dopamine and Neuropeptide Signaling in a Distributed Neuronal Network
2018
Leishmaniasis
1999 Standout
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Interferon-γ and interleukin-12 pathway defects and human disease
2000
Mycobacterium tuberculosis CDC1551 Induces a More Vigorous Host Response In Vivo and In Vitro, But Is Not More Virulent Than Other Clinical Isolates
1999
An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases
2007 Standout
Cell biology and molecular basis of denitrification
1997 Standout
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Single Cell Analysis Reveals That IL-4 Receptor/Stat6 Signaling Is Not Required for the In Vivo or In Vitro Development of CD4+ Lymphocytes with a Th2 Cytokine Profile
2000
A Genetic Analysis of the Caenorhabditis elegans Detoxification Response
2017
The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response
2009
T Helper Cell Subsets in Insulin-Dependent Diabetes
1995 Science
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
2015
Low Dose TGF-β Attenuates IL-12 Responsiveness in Murine Th Cells
1998
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
2007 StandoutNobel
T cell genetic background determines default T helper phenotype development in vitro.
1995
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
2016 StandoutNobel
Liprin-α proteins: scaffold molecules for synapse maturation
2007
Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells.
1998
Infection of Human Macrophages and Dendritic Cells with Mycobacterium tuberculosis Induces a Differential Cytokine Gene Expression That Modulates T Cell Response
2001
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.
1995
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
IL-12 Is Required to Maintain a Th1 Response DuringLeishmania majorInfection
2000
Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.
1994 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126 )
2007
Multifactorial Nature of Human Immunodeficiency Virus Disease: Implications for Therapy
1993 Science
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Vaccination with DNA Encoding the Immunodominant LACK Parasite Antigen Confers Protective Immunity to Mice Infected with Leishmania major
1997
The Adjuvant Effect of Interleukin-12 in a Vaccine Against Leishmania major
1994 Science
Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductase
2011 StandoutNobel
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Deconstructing complexin function in activating and clamping Ca 2+ -triggered exocytosis by comparing knockout and knockdown phenotypes
2013 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Overproduction of TNF-α by CD8+ Type 1 Cells and Down-Regulation of IFN-γ Production by CD4+ Th1 Cells Contribute to Toxic Shock-Like Syndrome in an Animal Model of Fatal Monocytotropic Ehrlichiosis
2004
A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective
2021
Works of Derek Sieburth being referenced
A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative-stress adaptation in mammals, C. elegans and D. melanogaster
2012
Regulation of Synaptic nlg-1/Neuroligin Abundance by the skn-1/Nrf Stress Response Pathway Protects against Oxidative Stress
2014
Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5
1992
An RNAi Screen Identifies Genes that Regulate GABA Synapses
2008
The Conserved SKN-1/Nrf2 Stress Response Pathway Regulates Synaptic Function in Caenorhabditis elegans
2013
Identification of Essential Amino Acids within the Proposed CuA Binding Site in Subunit II of Cytochrome c Oxidase
1995
Aging and SKN-1-dependent Loss of 20S Proteasome Adaptation to Oxidative Stress inC. elegans
2016
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
SUR-8, a Conserved Ras-Binding Protein with Leucine-Rich Repeats, Positively Regulates Ras-Mediated Signaling in C. elegans
1998
A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction
1999
PKC-1 regulates secretion of neuropeptides
2006
Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response.
1993
Interleukin-12 production by human monocytes infected with Mycobacterium tuberculosis: role of phagocytosis
1996
Interleukin 12: A key modulator of immune function
1994