Derek M. Smith

Evolution of the Cancer Stem Cell Model

The role of the gut microbiota in nutrition and health

Targeting NF- B activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy

NF-κB and IKK as therapeutic targets in cancer

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

Clonal evolution in cancer

ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome

Insufficient interleukin‐12 signalling favours differentiation of human CD4⁺ and CD8⁺ T cells into GATA‐3⁺ and GATA‐3⁺ T‐bet⁺ subsets in humanized mice

Identification of Pancreatic Cancer Stem Cells

Correction: Nr4a1-eGFP Is a Marker of Striosome-Matrix Architecture, Development and Activity in the Extended Striatum

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

Characterization of clonogenic multiple myeloma cells

Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses

Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice

Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice

Partial ablation of mu-opioid receptor rich striosomes produces deficits on a motor-skill learning task

Human AML cells in NOD/SCID mice: engraftment potential and gene expression