Citation Impact
Citing Papers
A Forward Chemical Screen Identifies Antibiotic Adjuvants in Escherichia coli
2012
Cell Type–Specific, Topoisomerase II–Dependent Inhibition of Hypoxia-Inducible Factor-1α Protein Accumulation by NSC 644221
2007
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Gastric cancer
2016 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Mismatch repair defects in cancer
2000
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Inhibition of autophagy with chloroquine is effective in melanoma
2013
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
AKT/PKB Signaling: Navigating Downstream
2007 Standout
DNA methylation in endometrial cancer
2010
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Targeting hypoxia cell signaling for cancer therapy
2007
Energy metabolism in tumor cells
2007
Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
2003 StandoutNobel
Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance
2013
Identification of a Second MutL DNA Mismatch Repair Complex (hPMS1 and hMLH1) in Human Epithelial Cells
2000
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Assembly and Molecular Activities of the MutS Tetramer
2003 StandoutNobel
Tumor Cell Metabolism: Cancer's Achilles' Heel
2008 Standout
The Frequency of Hereditary Defective Mismatch Repair in a Prospective Series of Unselected Colorectal Carcinomas
2001
Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies
2011
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
The ABC of APC
2001
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Hypoxia signalling in cancer and approaches to enforce tumour regression
2006 Nature
Development of HIF‐1 inhibitors for cancer therapy
2009
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Role of DNA mismatch repair in apoptotic responses to therapeutic agents
2004
Hypoxia-inducible factors: central regulators of the tumor phenotype
2007
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Regulation of Vascularization by Hypoxia‐Inducible Factor 1
2009 StandoutNobel
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
2013
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
The Hallmarks of Aging
2013 Standout
Widespread and tissue specific age-related DNA methylation changes in mice
2010
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Development of novel therapeutic strategies that target HIF-1
2006 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Biomarkers for Early Detection and as Surrogate Endpoints in Cancer Prevention Trials: Issues and Opportunities
2010
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes
2001 StandoutNobel
Evaluation of HIF-1 inhibitors as anticancer agents
2007 StandoutNobel
Angiogenesis as a therapeutic target
2005 StandoutNature
Antibacterial drug discovery in the resistance era
2016 StandoutNature
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
DNA MISMATCH REPAIR AND GENETIC INSTABILITY
2000
Meeting Report: Exploiting the Tumor Microenvironment for Therapeutics
2006 StandoutNobel
CHK1 and CHK2 are differentially involved in mismatch repair–mediated 6-thioguanine-induced cell cycle checkpoint responses
2004
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
A gene hypermethylation profile of human cancer.
2001 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine
2017
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
Combination of Antiangiogenic Therapy With Other Anticancer Therapies: Results, Challenges, and Open Questions
2005
Cancer Genome Landscapes
2013 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Genetic susceptibility to non-polyposis colorectal cancer
1999
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Modulating Hypoxia-Inducible Transcription by Disrupting the HIF-1–DNA Interface
2007
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound
2016
Works of Dehe Kong being referenced
Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
2005
Modulation of Aldehyde Dehydrogenase Activity Affects (±)-4-Hydroxy-2E-nonenal (HNE) Toxicity and HNE–Protein Adduct Levels in PC12 Cells
2011
Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas
1997
Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
2000
Hypermethylation of the hMLH1 gene promoter is associated with microsatellite instability in early human gastric neoplasia
2001
Targeting the PAS-A Domain of HIF-1α for Development of Small Molecule Inhibitors of HIF-1
2006
"Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies.
2003
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability.
1999
Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells
1999