Citation Impact
Citing Papers
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
2013 StandoutScience
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Molecular Classification and Prognostication of Adrenocortical Tumors by Transcriptome Profiling
2009
IGF-I Regulates Redox Status in Breast Cancer Cells by Activating the Amino Acid Transport Molecule xC−
2014
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells
2006
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
The role of the insulin-like growth factor-1 system in breast cancer
2015
Discovery and engineering of enhanced SUMO protease enzymes
2018 StandoutNobel
Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA
2012 StandoutNobel
Role of insulin-like growth factor 1 receptor signalling in cancer
2005
Collagen density promotes mammary tumor initiation and progression
2008
Insulin-like growth factor-1 prevents miR-122 production in neighbouring cells to curtail its intercellular transfer to ensure proliferation of human hepatoma cells
2014
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Breast Cancer and Obesity: An Update
2003
Acromegaly
2006 Standout
Functional responses and in vivo anti-tumour activity of h7C10: A humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors
2007
IGF-I mediated survival pathways in normal and malignant cells
2006
The insulin-like growth factor system in advanced breast cancer
2003
Coordinated Activities of Human Dicer Domains in Regulatory RNA Processing
2012 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Comparison of SUMO fusion technology with traditional gene fusion systems: Enhanced expression and solubility with SUMO
2005
Insulin-like growth factors and neoplasia
2004
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Insulin/IGF-I Signaling Pathways Enhances Tumor Cell Invasion through Bisecting GlcNAc N-glycans Modulation. An Interplay with E-Cadherin
2013
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
2007 Standout
Long‐term effects of calorie or protein restriction on serum IGF‐1 and IGFBP‐3 concentration in humans
2008
Obesity and cancer risk: the role of the insulin–IGF axis
2006
GSVA: gene set variation analysis for microarray and RNA-Seq data
2013 Standout
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Insulin receptor expression by human prostate cancers
2008
Crystal structures of fusion proteins with large‐affinity tags
2003
The JAZ family of repressors is the missing link in jasmonate signalling
2007 StandoutNature
Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis in Mycobacterium tuberculosis
2011 StandoutNobel
Serum concentrations of IGF‐I, IGFBP‐3 and c‐peptide and risk of hyperplasia and cancer of the breast in postmenopausal women
2003
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
Engineered T cells: the promise and challenges of cancer immunotherapy
2016
Controlled Intracellular Processing of Fusion Proteins by TEV Protease
2000
Rapid screening for improved solubility of small human proteins produced as fusion proteins in Escherichia coli
2002
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
2017 StandoutNobel
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
2004 Standout
Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer
2005
A tense situation: forcing tumour progression
2009 Standout
The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of 111In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin)
2008
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization
2003
The Three-Dimensional Structure of the Autoproteolytic, Nuclear Pore-Targeting Domain of the Human Nucleoporin Nup98
2002
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Overview of tag protein fusions: from molecular and biochemical fundamentals to commercial systems
2003
Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence
2007
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
2011 Standout
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Tumour-educated macrophages promote tumour progression and metastasis
2004 Standout
Delivering quantum dots to cells: bioconjugated quantum dots for targeted and nonspecific extracellular and intracellular imaging
2010
Communication by Extracellular Vesicles: Where We Are and Where We Need to Go
2016 Standout
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
2008 Standout
The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth
2006
Pancreatic Cancer
2010 Standout
siRNA Repositioning for Guide Strand Selection by Human Dicer Complexes
2011 StandoutNobel
SUMO fusion technology for difficult-to-express proteins
2005
Bioconjugated quantum dots for cancer research: Present status, prospects and remaining issues
2009
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
Construction of a set Gateway-based destination vectors for high-throughput cloning and expression screening in Escherichia coli
2005
The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer
2008
Prospects for adoptive immunotherapy of pancreatic cancer using chimeric antigen receptor-engineered T-cells
2015
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
Circulating levels of insulin‐like growth factor I, its binding proteins ‐1,‐2, ‐3, C‐peptide and risk of postmenopausal breast cancer
2003
Insulin-Like Growth Factor 1 Receptor Targeted Therapeutics: Novel Compounds and Novel Treatment Strategies for Cancer Medicine
2008
Involvement of Insulin Receptor Substrate 2 in Mammary Tumor Metastasis
2004
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Genetic Polymorphisms Involved in Insulin-like Growth Factor (IGF) Pathway in Relation to Mammographic Breast Density and IGF Levels
2008
The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer
2016
The Type 1 Insulin-Like Growth Factor Receptor Pathway
2008
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
Nonendocytic Delivery of Functional Engineered Nanoparticles into the Cytoplasm of Live Cells Using a Novel, High-Throughput Microfluidic Device
2012 StandoutNobel
Insulin Receptor Isoforms in Physiology and Disease: An Updated View
2017
Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
2004 Standout
Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor
2007
Blockade of Paracrine Supply of Insulin-Like Growth Factors Using Neutralizing Antibodies Suppresses the Liver Metastasis of Human Colorectal Cancers
2005
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Microfluidics in the selection of affinity reagents for the detection of cancer: paving a way towards future diagnostics
2016
Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis
2008
Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail
2007
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Down-regulation of Type I Insulin-like Growth Factor Receptor Increases Sensitivity of Breast Cancer Cells to Insulin
2007
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Insulin-Like Growth Factor-I, IGF-Binding Protein-3, and Mammographic Breast Density
2005
Anoikis Resistance: An Essential Prerequisite for Tumor Metastasis
2012
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance
2008
Sweeping Away Protein Aggregation with Entropic Bristles: Intrinsically Disordered Protein Fusions Enhance Soluble Expression
2012
Phase I Dose Escalation Study of the Anti–Insulin-Like Growth Factor-I Receptor Monoclonal Antibody CP-751,871 in Patients with Refractory Solid Tumors
2007
Emerging Droplet Microfluidics
2017 Standout
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
2007
Works of Deepali Sachdev being referenced
[20] Fusions to maltose-binding protein: Control of folding and solubility in protein purification
2000
Combined Effects of Tamoxifen and a Chimeric Humanized Single Chain Antibody against the Type I IGF Receptor on Breast Tumor GrowthIn vivo
2003
Solubility of Proteins Isolated from Inclusion Bodies Is Enhanced by Fusion to Maltose-Binding Protein or Thioredoxin
1998
Detection and downregulation of type I IGF receptor expression by antibody-conjugated quantum dots in breast cancer cells
2008
Properties of Soluble Fusions Between Mammalian Aspartic Proteinases and Bacterial Maltose-Binding Protein
1999
Inhibitors of Insulin-like Growth Factor Signaling: A Therapeutic Approach for Breast Cancer
2006
Order of Fusions between Bacterial and Mammalian Proteins Can Determine Solubility inEscherichia coli
1998
EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice
2016
IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas
2015
Motility Response to Insulin-like Growth Factor-I (IGF-I) in MCF-7 Cells is Associated with IRS-2 Activation and Integrin Expression
2004
A Dominant Negative Type I Insulin-like Growth Factor Receptor Inhibits Metastasis of Human Cancer Cells
2004
The IGF system and breast cancer.
2001
The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival
2009
Acquired Resistance to Tamoxifen Is Associated with Loss of the Type I Insulin-like Growth Factor Receptor: Implications for Breast Cancer Treatment
2012
A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
2003
Disrupting insulin-like growth factor signaling as a potential cancer therapy
2007
Down-regulation of Insulin Receptor by Antibodies against the Type I Insulin-Like Growth Factor Receptor: Implications for Anti–Insulin-Like Growth Factor Therapy in Breast Cancer
2006