Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
2007
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
2018 StandoutNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
2017
The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
2014
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Modulating Co-Stimulation During Antigen Presentation to Enhance Cancer Immunotherapy
2012
Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?
2018
Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients
2007
An Overview of Animal Models of Pain: Disease Models and Outcome Measures
2013
Rheumatoid arthritis
2018 Standout
Effects of Flavonoids and other Polyphenols on Inflammation
2011 Standout
Mitogen-activated protein kinases in innate immunity
2013
Rheumatoid arthritis
2016 Standout
Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b
2005
Bortezomib inhibits human osteoclastogenesis
2007
Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes
2010
Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis
2011
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
Autoinflammatory Disease Reloaded: A Clinical Perspective
2010 Standout
Transcriptional Integration of TLR2 and TLR4 Signaling at the NCoR Derepression Checkpoint
2009
Crosstalk of reactive oxygen species and NF-κB signaling
2010 Standout
Advances in metal-induced oxidative stress and human disease
2011 Standout
TGF-β: the master regulator of fibrosis
2016 Standout
Juvenile idiopathic arthritis
2007 Standout
Thymoquinone: Potential cure for inflammatory disorders and cancer
2011 Standout
Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-κB and AP-1 as prime targets
2006
Role of MKK3–p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice
2008
Critical Role of Synovial Tissue–Resident Macrophage and Fibroblast Subsets in the Persistence of Joint Inflammation
2021
JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain
2009
PUMA regulation and proapoptotic effects in fibroblast‐like synoviocytes
2006
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Mitogen activated protein kinase inhibitors: where are we now and where are we going?
2006
Central sensitization: Implications for the diagnosis and treatment of pain
2010 Standout
MAPKs and their relevance to arthritis and inflammation
2007
Antiviral gene expression in rheumatoid arthritis: Role of IKKϵ and interferon regulatory factor 3
2007
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
2011 Standout
Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response
2007
The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now?
2008
How antirheumatic drugs protect joints from damage in rheumatoid arthritis
2008
Sarcoidosis
2013 Standout
The complexity of NF-κB signaling in inflammation and cancer
2013 Standout
Synergistic benefit in inflammatory arthritis by targeting IκB kinase ε and interferon β
2008
Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis
2010
Therapeutic antibodies for autoimmunity and inflammation
2010
Antibody therapy of cancer
2012 Standout
Human FoxP3+ regulatory T cells in systemic autoimmune diseases
2011 StandoutNobel
Regulation of the immune response by stress‐activated protein kinases
2009
The Role of Glia in the Spinal Cord in Neuropathic and Inflammatory Pain
2015
A Benzothiophene Inhibitor of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Inhibits Tumor Necrosis Factor α Production and Has Oral Anti-Inflammatory Efficacy in Acute and Chronic Models of Inflammation
2010
Recent progress in rheumatoid arthritis genetics: one step towards improved patient care
2009
The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting
2016
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2010
2011 Standout
A Novel Spleen Tyrosine Kinase Inhibitor Blocks c-Jun N-Terminal Kinase-Mediated Gene Expression in Synoviocytes
2006
The p38 mitogen-activated protein kinase (MAPK) pathway in rheumatoid arthritis
2007
IκB kinase β (IKKβ/IKK2/IKBKB)—A key molecule in signaling to the transcription factor NF-κB
2008
Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
2017
Increased presence and differential molecular imprinting of transit amplifying cells in psoriasis
2019
Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors
2012
Rheumatoid arthritis
2010 Standout
Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
2008
Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies
2018
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
2008
Dysregulation of p38 and MKP-1 in Response to NOD1/TLR4 Stimulation in Sarcoid Bronchoalveolar Cells
2010
Hidradenitis suppurativa
2020 Standout
Regulation of type I interferon responses
2013 Standout
Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials
2015 Standout
Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony
2019 Standout
Efficacy, pharmacodynamics, and safety of VX‐702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double‐blind, placebo‐controlled clinical studies
2009
The many facets of macrophages in rheumatoid arthritis
2019
Tenosynovitis and osteoclast formation as the initial preclinical changes in a murine model of inflammatory arthritis
2006
Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
2009 Standout
Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway
2006
MAP kinase and pain
2008 Standout
Regulation of Peripheral Inflammation by the Central Nervous System
2010
Garden of therapeutic delights: new targets in rheumatic diseases
2009
Inflammatory bone loss: pathogenesis and therapeutic intervention
2012 Standout
JNK1 is not essential for TNF-mediated joint disease
2004
Fibroblast‐like synoviocytes: key effector cells in rheumatoid arthritis
2009 Standout
Therapeutic Targeting of B Cells for Rheumatic Autoimmune Diseases
2011
Nrf2 activation improves experimental rheumatoid arthritis
2023 StandoutNobel
The MAPK pathway across different malignancies: A new perspective
2014 Standout
p38 MAPK, Microglial Signaling, and Neuropathic Pain
2007
Acquisition, Culture, and Phenotyping of Synovial Fibroblasts
2007
Cross-talk between MEK1/2-ERK1/2 signaling and G protein-couple signaling in synoviocytes of collagen-induced arthritis rats
2008
Roles of Mitogen-Activated Protein Kinases in Osteoclast Biology
2018
The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
2018 StandoutNobel
ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney
2014
Platelet-Rich Plasma
2009 Standout
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
Mechanisms of Diabetic Complications
2013 Standout
Nerve Conduction Blockade in the Sciatic Nerve Prevents but Does Not Reverse the Activation of p38 Mitogen-activated Protein Kinase in Spinal Microglia in the Rat Spared Nerve Injury Model
2007
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
2019 Standout
Interleukin-1 (IL-1) Pathway
2010
Macrophages, Inflammation, and Insulin Resistance
2010 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Rebamipide Suppresses Collagen‐Induced Arthritis Through Reciprocal Regulation of Th17/Treg Cell Differentiation and Heme Oxygenase 1 Induction
2013
Works of Deepa Hammaker being referenced
Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis
2006
Regulation of p38 MAPK by MAPK Kinases 3 and 6 in Fibroblast-Like Synoviocytes
2005
Role of MAPK Kinase 6 in Arthritis: Distinct Mechanism of Action in Inflammation and Cytokine Expression
2009
Synoviocyte Innate Immune Responses: I. Differential Regulation of Interferon Responses and the JNK Pathway by MAPK Kinases
2008
PUMA-mediated apoptosis in fibroblast-like synoviocytes does not require p53
2006
Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes
2016
Regulation of the JNK pathway by TGF-beta activated kinase 1 in rheumatoid arthritis synoviocytes
2007
Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation
2016
Gadd45β deficiency in rheumatoid arthritis: Enhanced synovitis through JNK signaling
2009
Epigenetics of inflammatory arthritis
2017
Expression of the MAPK kinases MKK‐4 and MKK‐7 in rheumatoid arthritis and their role as key regulators of JNK
2003
“Go upstream, young man”: lessons learned from the p38 saga
2009
Regulation of Peripheral Inflammation by Spinal p38 MAP Kinase in Rats
2006
Signal transduction networks in rheumatoid arthritis
2003
Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss
2014
Suppression of collagen-induced arthritis in growth arrest and DNA damage-inducible protein 45β-deficient mice
2011
Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis
2011
Regulation of JNK by MKK‐7 in fibroblast‐like synoviocytes
2006
Assessment of rituximab's immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results
2007
Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: Advantages of targeting upstream kinases MKK‐3 or MKK‐6
2012
LBH Gene Transcription Regulation by the Interplay of an Enhancer Risk Allele and DNA Methylation in Rheumatoid Arthritis
2016
Regulation of c-Jun Phosphorylation by the IκB Kinase-ε Complex in Fibroblast-Like Synoviocytes
2005
Regulation of c-Jun N-Terminal Kinase by MEKK-2 and Mitogen-Activated Protein Kinase Kinase Kinases in Rheumatoid Arthritis
2004
Correction: Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss
2014
Phosphoinositide 3-Kinase δ Regulates Migration and Invasion of Synoviocytes in Rheumatoid Arthritis
2014