Citation Impact
Citing Papers
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
2008 StandoutNobel
γ-Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment
2010
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
2022 StandoutNobel
Surveillance mechanism linking Bub1 loss to the p53 pathway
2007
Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1
2009
Evolution of the Cancer Stem Cell Model
2014 Standout
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
Regulation of the breast cancer stem cell phenotype by hypoxia-inducible factors
2015 StandoutNobel
Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis
2010
Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors
2011
Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors
2005
Emerging roles of PKM2 in cell metabolism and cancer progression
2012 StandoutNobel
Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer
2005
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism
2010 StandoutNobel
From traditional Chinese medicine to rational cancer therapy
2007 Standout
Signalling dynamics in the spindle checkpoint response
2014
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
2015 Standout
Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death
2005
Chromatin Modifications and Their Function
2007 Standout
The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics
2013
Searching for the elusive targets of farnesyltransferase inhibitors
2003
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment
2017 StandoutNobel
Network pharmacology: the next paradigm in drug discovery
2008 Standout
The dynamic protein Knl1 – a kinetochore rendezvous
2014
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
2016 StandoutNobel
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Naturally occurring B-cell responses to breast cancer
2003
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore
2012
Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding
2009
The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
2015
Functional and physical communication between oncoproteins and tumor suppressors
2005
Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization
2019 StandoutNobel
Mitotic Transcription Installs Sgo1 at Centromeres to Coordinate Chromosome Segregation
2015
Targeting cancer with small molecule kinase inhibitors
2008 Standout
FoxM1 is required for execution of the mitotic programme and chromosome stability
2005 Standout
Tocotrienol research: past into present
2012
Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs
2008
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
2011
The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1
2007
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia
2010
Dynamic regulation of stem cell specification and maintenance by hypoxia-inducible factors
2015 StandoutNobel
KSHV induces aerobic glycolysis and angiogenesis through HIF-1-dependent upregulation of pyruvate kinase 2 in Kaposi’s sarcoma
2015 StandoutNobel
Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy
2014 Standout
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
Non-coding RNAs in human disease
2011 Standout
Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint
2007
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells
2015
The immune contexture in human tumours: impact on clinical outcome
2012 Standout
Reflecting on 25 years with MYC
2008 Standout
Pyroptosis: A new frontier in cancer
2019 Standout
Drug distribution in tumors: Mechanisms, role in drug resistance, and methods for modification
2007
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment
2005
Targeting autophagy in cancer
2017 Standout
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
2007 Standout
Non-apoptotic cell death in malignant tumor cells and natural compounds
2018
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Mitosin/CENP-F as a Negative Regulator of Activating Transcription Factor-4
2005
Search for Protein Farnesyltransferase Inhibitors of Microbial Origin: Our Strategy and Results as well as the Results Obtained by Other Groups
2007 StandoutNobel
Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint
2010
Aurora-kinase inhibitors as anticancer agents
2004
The spindle assembly checkpoint: Preventing chromosome mis‐segregation during mitosis and meiosis
2006
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc
2002
Drug Resistance and the Solid Tumor Microenvironment
2007 Standout
Photodynamic therapy – mechanisms, photosensitizers and combinations
2018 Standout
The spindle-assembly checkpoint in space and time
2007 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The integrated stress response
2016 Standout
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
2007
Stem cell cultures derived from pediatric brain tumors accurately model the originating tumors
2017
CAAX-box protein, prenylation process and carcinogenesis.
2009
A Molecular View of Kinetochore Assembly and Function
2017
Guide snoRNAs: Drivers or Passengers in Human Disease?
2018
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis
2011
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
2010
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
Vitamin E δ-Tocotrienol Augments the Antitumor Activity of Gemcitabine and Suppresses Constitutive NF-κB Activation in Pancreatic Cancer
2011
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
2008
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression
2012
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity
2007
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
2014 Standout
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
2016 StandoutNobel
Mitotic spindle checkpoint inactivation by trichostatin A defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents
2005
Works of Deema Hussein being referenced
Comprehensive molecular biomarker identification in breast cancer brain metastases
2017
Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion
2010
Current and emerging biomarkers in tumors of the central nervous system: Possible diagnostic, prognostic and therapeutic applications
2017
d-δ-Tocotrienol-Mediated Suppression of the Proliferation of Human PANC-1, MIA PaCa-2, and BxPC-3 Pancreatic Carcinoma Cells
2009
Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells
2001
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
2004
Farnesylation of Cenp-F is required for G2/M progression and degradation after mitosis
2002
Chronic hypoxia promotes hypoxia-inducible factor-1α–dependent resistance to etoposide and vincristine in neuroblastoma cells
2006
Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint
2005