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Human antibodies to the conserved region of the M protein: opsonization of heterologous strains of group A streptococci
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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
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Many group A streptococcal strains express two different immunoglobulin‐binding proteins, encoded by closely linked genes: characterization of the proteins expressed by four strains of different M‐type
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Capturing host plasmin(ogen): a common mechanism for invasive pathogens?
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REPuter: the manifold applications of repeat analysis on a genomic scale
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Nucleotide substitutions and small‐scale insertion produce size and antigenic variation in group A streptococcal M1 protein
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Recombinant, octavalent group A streptococcal M protein vaccine
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Characterization of a gene coding for a type IIo bacterial IgG-binding protein
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Metagenomic biomarker discovery and explanation
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Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
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Evolutionary Implications of Microbial Genome Tetranucleotide Frequency Biases
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Genetic variability of the emm-related genes of the large vir regulon of group A streptococci: potential intra- and intergenomic recombination events
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Group A Streptococcus: allelic variation, population genetics, and host-pathogen interactions
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Controlling Antimicrobial Resistance through Targeted, Vaccine-Induced Replacement of Strains
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Lysogenic Transfer of Group AStreptococcusSuperantigen Gene among Streptococci
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Group A Streptococcal Infections and Acute Rheumatic Fever
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Papillomaviruses and cancer: from basic studies to clinical application
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Expression of different group A streptococcal M proteins in an isogenic background demonstrates diversity in adherence to and invasion of eukaryotic cells
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Understanding the mechanisms and drivers of antimicrobial resistance
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Streptococcal Infections of Skin and Soft Tissues
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Functional analysis of the group A streptococcal luxS/AI-2 system in metabolism, adaptation to stress and interaction with host cells
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Towards a prokaryotic genomic taxonomy
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Genome Sequence of a Serotype M28 Strain of Group AStreptococcus:Potential New Insights into Puerperal Sepsis and Bacterial Disease Specificity
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Inactivation of single genes within the virulence regulon of an M2 group A streptococcal isolate result in differences in virulence for chicken embryos and for mice
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Re-evaluating prokaryotic species
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Prokaryotic Evolution in Light of Gene Transfer
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Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils
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The primary transcriptome of the major human pathogen Helicobacter pylori
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Characterization of a type II'o group A streptococcal immunoglobulin-binding protein
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RHEUMATIC FEVER
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Role of the conserved C‐repeat region of the M protein of Streptococcus pyogenes
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Target activation by regulatory RNAs in bacteria
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The challenge of emerging and re-emerging infectious diseases
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Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study
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Intranasal Immunization with Recombinant Group A Streptococcal M Protein Fragment Fused to the B Subunit of Escherichia coli Labile Toxin Protects Mice against Systemic Challenge Infections
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Molecular basis of group A streptococcal virulence
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Identification of superantigen genesspeM,ssa, andsmeZin invasive strains of beta-hemolytic group C and G streptococci recovered from humans
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Gain and Loss of Multiple Genes During the Evolution of Helicobacter pylori
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A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin
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Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine
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Genome Sequence of an M3 Strain of Streptococcus pyogenes Reveals a Large-Scale Genomic Rearrangement in Invasive Strains and New Insights into Phage Evolution
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The relative contributions of recombination and point mutation to the diversification of bacterial clones
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A microbial symbiosis factor prevents intestinal inflammatory disease
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Sex and virulence in Escherichia coli: an evolutionary perspective
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The Biology of CRISPR-Cas: Backward and Forward
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Exploring protein fitness landscapes by directed evolution
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
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Investigating the biological and clinical significance of human dysbioses
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Changing epidemiology of group A streptococcal infection in the USA
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Staphylococcus aureusInfections
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The multilocus sequence typing network: mlst.net
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Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis
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Community structure and metabolism through reconstruction of microbial genomes from the environment
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Horizontal gene transfer in the evolution of group A streptococcal emm‐like genes: gene mosaics and variation in Vir regulons
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Toxin‐Gene Profile Heterogeneity among Endemic Invasive European Group A Streptococcal Isolates
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Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
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Development of an unambiguous and discriminatory multilocus sequence typing scheme for the Streptococcus zooepidemicus group
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Development of a Multilocus Sequence Typing Scheme for the Pig Pathogen Streptococcus suis : Identification of Virulent Clones and Potential Capsular Serotype Exchange
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Analysis of immunoglobulin G-binding-protein expression by invasive isolates of Streptococcus pyogenes
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Streptococci and Rheumatic Fever
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Association of type II immunoglobulin G-binding protein expression and survival of group A streptococci in human blood
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Inference of Bacterial Microevolution Using Multilocus Sequence Data
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Pathogenesis of Group A Streptococcal Infections
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DNA sequence of the serum opacity factor of group A streptococci: identification of a fibronectin-binding repeat domain
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The changing face of rheumatic fever in the 20th century
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Characterization of Biofilm Formation by Clinically Relevant Serotypes of Group A Streptococci
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Two major classes in the M protein family in group A streptococci.
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Sexual isolation and speciation in bacteria.
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First Insights into the Evolution of Streptococcus uberis : a Multilocus Sequence Typing Scheme That Enables Investigation of Its Population Biology
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Shifting the genomic gold standard for the prokaryotic species definition
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Sequence type analysis and recombinational tests (START)
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Characterization of group A streptococci (Streptococcus pyogenes): correlation of M-protein and emm-gene type with T-protein agglutination pattern and serum opacity factor
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In the light of directed evolution: Pathways of adaptive protein evolution
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Staphylococcus aureus binding to human nasal mucin
1996
Cloning, sequencing, and expression of a fibronectin/fibrinogen-binding protein from group A streptococci
1994
Protection Against Streptococcal Pharyngeal Colonization with a Vaccinia: M Protein Recombinant
1989 Science
Specific binding of the activator Mga to promoter sequences of the emm and scpA genes in the group A streptococcus
1995
PAM, a novel plasminogen-binding protein from Streptococcus pyogenes.
1993
The group A streptococcal virR49 gene controls expression of four structural vir regulon genes
1995
Anti-Hsp65 antibodies recognize M proteins of group A streptococci
1996
Dissemination of the Phage-Associated Novel Superantigen Gene speL in Recent Invasive and Noninvasive Streptococcus pyogenes M3/T3 Isolates in Japan
2002
Regulation of SpeB inStreptococcus pyogenesby pH and NaCl: a Model for In Vivo Gene Expression
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Characterization of a conserved helper-T-cell epitope from group A Streptococcal M proteins
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Analysis of genes encoding two unique type IIa immunoglobulin G-binding proteins expressed by a single group A streptococcal isolate
1994
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
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Identification and Characterization of a Novel Secreted Immunoglobulin Binding Protein from Group A Streptococcus
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Genome-wide molecular dissection of serotype M3 group A Streptococcus strains causing two epidemics of invasive infections
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Immunoglobulins to Group A Streptococcal Surface Molecules Decrease Adherence to and Invasion of Human Pharyngeal Cells
1998
INTERACTION OF ANTIGENS AND ANTIBODIES AT MUCOSAL SURFACES
1997
Analysis of the role of M24 protein in group A streptococcal adhesion and colonization by use of omega-interposon mutagenesis
1994
Streptococcal M protein: molecular design and biological behavior
1989
Roles of mutation and recombination in the evolution of protein thermodynamics
2002 StandoutNobel
Environmental regulation of virulence in group A streptococci: transcription of the gene encoding M protein is stimulated by carbon dioxide
1992
CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis
2016
Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin.
1992
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
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Identification of a divergent M protein gene and an M protein-related gene family in Streptococcus pyogenes serotype 49
1989
Multilocus Sequence Typing System for Group B Streptococcus
2003
Intranasal immunization with C5a peptidase prevents nasopharyngeal colonization of mice by the group A Streptococcus
1997
Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks
2002
Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme
2001
Global epithelial cell transcriptional responses reveal Streptococcus pyogenes Fas regulator activity association with bacterial aggressiveness
2005
Association between expression of immunoglobulin G-binding proteins by group A streptococci and virulence in a mouse skin infection model
1993
Impact of M49, Mrp, Enn, and C5a Peptidase Proteins on Colonization of the Mouse Oral Mucosa byStreptococcus pyogenes
1998
Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens
1990
Expression of the Arp protein, a member of the M protein family, is not sufficient to inhibit phagocytosis of Streptococcus pyogenes
1995
Role of RopB in Growth Phase Expression of the SpeB Cysteine Protease ofStreptococcus pyogenes
2003
Genomic insights that advance the species definition for prokaryotes
2005 Standout
Fancy footwork in the sequence space shuffle
2006 StandoutNobel
Role of putative virulence factors of Streptococcus pyogenes in mouse models of long-term throat colonization and pneumonia
1997
Site-Specific Manifestations of Invasive Group A Streptococcal Disease: Type Distribution and Corresponding Patterns of Virulence Determinants
2003
Sortases and the Art of Anchoring Proteins to the Envelopes of Gram-Positive Bacteria
2006
eBURST: Inferring Patterns of Evolutionary Descent among Clusters of Related Bacterial Genotypes from Multilocus Sequence Typing Data
2004 Standout
Development of a Multilocus Sequence Typing Method for Analysis of Listeria monocytogenes Clones
2003
Survey of emm gene sequences and T-antigen types from systemic Streptococcus pyogenes infection isolates collected in San Francisco, California; Atlanta, Georgia; and Connecticut in 1994 and 1995
1997
Relative contributions of hyaluronic acid capsule and M protein to virulence in a mucoid strain of the group A Streptococcus
1997
What are Bacterial Species?
2002
Immunological Relationship between the Class I Epitope of Streptococcal M Protein and Myosin
1998
Nasal Immunization of Mice with Human Papillomavirus Type 16 Virus-Like Particles Elicits Neutralizing Antibodies in Mucosal Secretions
1998
On the conservative nature of intragenic recombination
2005 StandoutNobel
Short-Sequence DNA Repeats in Prokaryotic Genomes
1998
Bacterial genomes in epidemiology—present and future
2013
Severe Streptococcal Infections in Historical Perspective
1992
Molecular analysis of human cardiac myosin-cross-reactive B- and T-cell epitopes of the group A streptococcal M5 protein
1997
Genetic diversity and relationships among Streptococcus pyogenes strains expressing serotype M1 protein: recent intercontinental spread of a subclone causing episodes of invasive disease
1995
How Clonal Is Staphylococcus aureus ?
2003
Evolution of Staphylococcus aureus by Large Chromosomal Replacements
2004
Epidemiology of Invasive Group AStreptococcusDisease in the United States, 1995–1999
2002
Recombination in Evolutionary Genomics
2002
The Microbial Engines That Drive Earth's Biogeochemical Cycles
2008 StandoutScience
Genetic Relatedness and Superantigen Expression in Group A Streptococcus Serotype M1 Isolates from Patients with Severe and Nonsevere Invasive Diseases
2000
Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination
1997 Standout
Invasive Group A Streptococcal Infections, Israel
2002
Characterization of Encapsulated and Noncapsulated Haemophilus influenzae and Determination of Phylogenetic Relationships by Multilocus Sequence Typing
2003
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
Role of M protein in pharyngeal colonization by group A streptococci in rats
1993
Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonization.
1995
Microbiota regulates immune defense against respiratory tract influenza A virus infection
2011 Standout
Sexual Isolation and Speciation in Bacteria
2002
The Streptococcus pyogenes Serotype M49 Nra-Ralp3 Transcriptional Regulatory Network and Its Control of Virulence Factor Expression from the Novel eno ralp3 epf sagA Pathogenicity Region
2007
Separation of T-cell-stimulating activity from streptococcal M protein
1992
Recombination and the Population Structures of Bacterial Pathogens
2001
The bacterial species definition in the genomic era
2006
A group A streptococcal Enn protein potentially resulting from intergenomic recombination exhibits atypical immunoglobulin‐binding characteristics
1994
A comparison of homologous recombination rates in bacteria and archaea
2008
A Secreted Receptor Related to M1 Protein of Streptococcus pyogenes Binds to Fibrinogen, IgG, and Albumin
1990
The In Vitro Interaction ofStreptococcus pyogeneswith Human Pharyngeal Cells Induces a Phage-Encoded Extracellular DNase
2002
Changing Streptococci and Prospects For The Global Eradication of Rheumatic Fever
1997
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Removal of Group B Streptococci Colonizing the Vagina and Oropharynx of Mice with a Bacteriophage Lytic Enzyme
2004
Works of Debra E. Bessen being referenced
Two-domain motif for IgG-binding activity by group A streptococcal emm gene products
1997
Serologic Evidence for a Class I Group A Streptococcal Infection among Rheumatic Fever Patients
1995
Protection against Streptococcal Pharyngeal Colonization with Vaccines Composed of M Protein Conserved Regions
1991
Presence of streptococcal pyrogenic exotoxin A and C genes in human isolates of group G streptococci
2003
Molecular evolution of a multigene family in group A streptococci.
1994
A Human IgG Receptor of Group A Streptococci Is Associated with Tissue Site of Infection and Streptococcal Class
1990
Genetic Linkage of Exotoxin Alleles andemmGene Markers for Tissue Tropism in Group A Streptococci
1999
Structural heterogeneity of the emm gene cluster in group A streptococci
1993
M Protein Expression Is Not Required for Resistance to Phagocytosis of Type 18 Group A Streptococci
1997
Molecular Markers for Throat and Skin Isolates of Group A Streptococci
1997
Population biology of Gram-positive pathogens: high-risk clones for dissemination of antibiotic resistance
2011
A Genetic‐Based Evaluation of the Principal Tissue Reservoir for Group A Streptococci Isolated from Normally Sterile Sites
1997
Streptococcal Upper Respiratory Tract Infections and Psychosocial Stress Predict Future Tic and Obsessive-Compulsive Symptom Severity in Children and Adolescents with Tourette Syndrome and Obsessive-Compulsive Disorder
2009
Genetic Correlates of Throat and Skin Isolates of Group A Streptococci
1996
Contrasting Molecular Epidemiology of Group A Streptococci Causing Tropical and Nontropical Infections of the Skin and Throat
2000
Nucleotide sequences of two adjacent M or M-like protein genes of group A streptococci: different RNA transcript levels and identification of a unique immunoglobulin A-binding protein
1992
Multilocus Sequence Typing ofStreptococcus pyogenesand the Relationships betweenemmType and Clone
2001
Evidence for two distinct classes of streptococcal M protein and their relationship to rheumatic fever.
1989
Genomic Localization of a T Serotype Locus to a Recombinatorial Zone Encoding Extracellular Matrix-Binding Proteins in Streptococcus pyogenes
2002
Differentiation between two biologically distinct classes of group A streptococci by limited substitutions of amino acids within the shared region of M protein-like molecules.
1990
Passive acquired mucosal immunity to group A streptococci by secretory immunoglobulin A.
1988
Localization of immunoglobulin A-binding sites within M or M-like proteins of group A streptococci
1994
Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci
2000
Recombination within natural populations of pathogenic bacteria: Short-term empirical estimates and long-term phylogenetic consequences
2001
Role of Streptococcal T Antigens in Superficial Skin Infection
2007
Heterogeneity in the Polarity of Nra Regulatory Effects on Streptococcal Pilus Gene Transcription and Virulence
2008
Synthetic peptide vaccine against mucosal colonization by group A streptococci. I. Protection against a heterologous M serotype with shared C repeat region epitopes.
1990
emm Typing and Validation of Provisional M Types for Group A Streptococci1
1999
Evolution and Global Dissemination of Macrolide-Resistant Group A Streptococci
2006
Multilocus Sequence Typing ofStreptococcus pyogenesRepresenting Most KnownemmTypes and Distinctions among Subpopulation Genetic Structures
2004
Allelic polymorphism of emm loci provides evidence for horizontal gene spread in group A streptococci.
1994
Natural Selection and Evolution of Streptococcal Virulence Genes Involved in Tissue-Specific Adaptations
2003
Humanized In Vivo Model for Streptococcal Impetigo
2000
Variation inStreptococcus pyogenesNAD+Glycohydrolase Is Associated with Tissue Tropism
2010
Roles of the plasminogen activator streptokinase and the plasminogen-associated M protein in an experimental model for streptococcal impetigo
2002
Influence of intranasal immunization with synthetic peptides corresponding to conserved epitopes of M protein on mucosal colonization by group A streptococci
1988