Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Mutant G-protein-coupled receptors as a cause of human diseases
2004
p300 Interacts with the N- and C-terminal Part of PPARγ2 in a Ligand-independent and -dependent Manner, Respectively
1999
Coordinate Regulation of the Expression of the Fatty Acid Transport Protein and Acyl-CoA Synthetase Genes by PPARα and PPARγ Activators
1997
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.
1996
Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice
1999
Functional Antagonism between CCAAT/Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter
1997
Degradation of the Peroxisome Proliferator-activated Receptor γ Is Linked to Ligand-dependent Activation
2000
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Tumor Necrosis Factor-α Causes Insulin Receptor Substrate-2-Mediated Insulin Resistance and Inhibits Insulin-Induced Adipogenesis in Fetal Brown Adipocytes1
1998
Regulation of the Transcriptional Activity of the Peroxisome Proliferator-activated Receptor α by Phosphorylation of a Ligand-independent trans-Activating Domain
1999
Abdominal obesity and metabolic syndrome
2006 StandoutNature
PPARgamma induces the insulin-dependent glucose transporter GLUT4 in the absence of C/EBPalpha during the conversion of 3T3 fibroblasts into adipocytes.
1998
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy
2006
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Subcutaneous or visceral adipose tissue expression of the PPARγ gene is not altered in the fatty ( ) Zucker rat
1998
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Oncogenic kinase signalling
2001 StandoutNature
Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.
1997
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.
1997
Phosphorylation of PPARs: from molecular characterization to physiological relevance
2004
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
NMR characterization of interleukin‐2 in complexes with the IL‐2Rα receptor component, and with low molecular weight compounds that inhibit the IL‐2/IL‐Rα interaction
2003
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies
2005
Effects of troglitazone on fat distribution in the treatment of male type 2 diabetes
1999
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Interferon-γ-induced Regulation of Peroxisome Proliferator-activated Receptor γ and STATs in Adipocytes
2001
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Regulation of Peroxisome Proliferator-activated Receptor γ Activity by Mitogen-activated Protein Kinase
1997
THIAZOLIDINEDIONES
1997
Ligand-independent Activation Domain in the N Terminus of Peroxisome Proliferator-activated Receptor γ (PPARγ)
1997
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
1997 StandoutNature
PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?
2003
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
1997 Standout
Glucose Transporters and Insulin Action — Implications for Insulin Resistance and Diabetes Mellitus
1999
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
1998 StandoutNature
Energy balance and food intake: The role of PPARγ gene polymorphisms
2006
Pioglitazone time-dependently reduces tumour necrosis factor-α level in muscle and improves metabolic abnormalities in Wistar fatty rats
1998
Altered Constitutive Expression of Fatty Acid-metabolizing Enzymes in Mice Lacking the Peroxisome Proliferator-activated Receptor α (PPARα)
1998
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
The Short- and Long-Term Effects of Tumor Necrosis Factor-α and BRL 49653 on Peroxisome Proliferator-Activated Receptor (PPAR)γ2 Gene Expression and Other Adipocyte Genes
1998
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Relationships of PPARγ and PPARγ2 mRNA levels to obesity, diabetes and hyperinsulinaemia in rhesus monkeys
1998
Potential Role of TNF-α in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
2000
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Signaling—2000 and Beyond
2000 Standout
Antagonists of protein–protein interactions
2000
The Nuclear Receptors Peroxisome Proliferator-activated Receptor α and Rev-erbα Mediate the Species-specific Regulation of Apolipoprotein A-I Expression by Fibrates
1998
Potent Prostaglandin A1 Analogs That Suppress Tumor Cell Growth through Induction of p21 and Reduction of Cyclin E
1998 StandoutNobel
Identification of ARA70 as a Ligand-enhanced Coactivator for the Peroxisome Proliferator-activated Receptor γ
1999
Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus.
1998
In VivoEffects of Pioglitazone on Uncoupling Protein-2 and -3 mRNA Levels in Skeletal Muscle of Hyperglycemic KK Mice
1998
Adipogenesis and Obesity: Rounding Out the Big Picture
1996
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27
2007
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Peroxisome Proliferator-activated Receptor-γ Ligands Inhibit Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity
2001
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Identification of Wortmannin-sensitive Targets in 3T3-L1 Adipocytes
1999
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
The hormone resistin links obesity to diabetes
2001 StandoutNature
The biology of leptin: a review.
1998
Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency
2000
Interferon-γ-mediated Activation and Ubiquitin-Proteasome-dependent Degradation of PPARγ in Adipocytes
2002
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
2006 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass
2003
Expression of Peroxisome Proliferator-Activated Receptor α (PPARα) in Primary Cultures of Human Vascular Endothelial Cells
1998
Genetic Modulation of PPARγ Phosphorylation Regulates Insulin Sensitivity
2003
Activation of Proliferator-activated Receptors α and γ Induces Apoptosis of Human Monocyte-derived Macrophages
1998
Src-dependent Tyrosine Phosphorylation Regulates Dynamin Self-assembly and Ligand-induced Endocytosis of the Epidermal Growth Factor Receptor
2002 StandoutNobel
Fluorescent indicators for imaging protein phosphorylation in single living cells
2002
Posttranslational Modifications of PPAR‐γ: Fine‐tuning the Metabolic Master Regulator
2009
Roles of PPARs in health and disease
2000 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome
2005
Mitogen-Activated Protein Kinase Activation Is Not Necessary for, but Antagonizes, 3T3-L1 Adipocytic Differentiation
1997
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States
2006 Standout
Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor-gamma in human adipocytes.
1999
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
2001 StandoutScience
ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION
1997
The peroxisome proliferator-activated receptorγ (PPARγ) as a regulator of monocyte/macrophage function
1999
Understanding Adipocyte Differentiation
1998 Standout
Strategien zur Modulation von Protein‐Protein‐Wechselwirkungen mit synthetischen Substanzen
2005
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
PPARs and Lipid Ligands in Inflammation and Metabolism
2011
Enhanced insulin-stimulated activation of phosphatidylinositol 3-kinase in the liver of high-fat-fed rats.
1999
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
1997 Standout
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation
2001
Tumor Necrosis Factor-α Decreases Akt Protein Levels in 3T3-L1 Adipocytes via the Caspase-Dependent Ubiquitination of Akt
2005
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARγ, adipogenesis, and insulin-responsive hexose transport
2006
Role of Skeletal Muscle in Thiazolidinedione Insulin Sensitizer (PPARγ Agonist) Action
1998
Pathophysiology and Pharmacological Treatment of Insulin Resistance*
2000
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
1996
Bioprospecting for Microbial Endophytes and Their Natural Products
2003 Standout
RXR Agonists Activate PPARα-Inducible Genes, Lower Triglycerides, and Raise HDL Levels In Vivo
1998
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.
1998 Standout
Role of Peroxisome Proliferator-Activated Receptor-γ in Maintenance of the Characteristics of Mature 3T3-L1 Adipocytes
2002
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of Deborah Szalkowski being referenced
Insulin- and Mitogen-activated Protein Kinase-mediated Phosphorylation and Activation of Peroxisome Proliferator-activated Receptor γ
1996
Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice
1996
Inhibition of Adipocyte Differentiation by HIV Protease Inhibitors
1999
PI 3-Kinase Activation Is Required for Insulin Stimulation of Glucose Transport into L6 Myotubes
1994
Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha.
1996
The basal SAR of a novel insulin receptor activator
2000
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1
2005
Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice
1999 Science
Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells
1995
Somatostatin Receptor Subtype 5 Regulates Insulin Secretion and Glucose Homeostasis
2003
Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in 3T3-L1 cells.
1995
Potentiation of Insulin Signaling in Tissues of Zucker Obese Rats After Acute and Long-Term Treatment With PPARγ Agonists
2002
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1
2005
Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes.
1994