Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
2013
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
HIV-1 reverse transcriptase inhibitor resistance mutations and fitness: A view from the clinic and ex vivo
2008
High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
2016 StandoutNature
A scoutRNA Is Required for Some Type V CRISPR-Cas Systems
2020 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Mechanism of IS200/IS605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection
2008
Expanding the Biologist’s Toolkit with CRISPR-Cas9
2015 StandoutNobel
Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III inStreptococcus pyogenes
2017 StandoutNobel
Mutation as a Stress Response and the Regulation of Evolvability
2007
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The growing impact of click chemistry on drug discovery
2003 StandoutNobel
Resistance to Protease Inhibitors
2001
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
2015 StandoutNobel
A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
2013
Novel nonpeptidic inhibitors of HIV-1 protease obtained via a new multicomponent chemistry strategy
2004
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Tipranavir
2008
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Tipranavir: a novel protease inhibitor for HIV therapy
2009
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
The biogenesis, biology and characterization of circular RNAs
2019 Standout
ROS Are Good
2016 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase
2012
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug reSistant patients with Tipranavir (RESIST) studies: an analysis of combined data from two randomised open-label trials
2006
Structure of the unusual seryl‐tRNA synthetase reveals a distinct zinc‐dependent mode of substrate recognition
2006
Antiretroviral Treatment of Adult HIV Infection
2012 Standout
Sirtuin Catalysis and Regulation
2012
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Genome engineering
2009
Genome-editing revolution: My whirlwind year with CRISPR
2015 StandoutNatureNobel
The Role of Sirtuins in Antioxidant and Redox Signaling
2017
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP)
2019 StandoutNobel
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
2012
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Nonhomologous End-Joining in Bacteria: A Microbial Perspective
2007
Ribonuclease III mechanisms of double‐stranded RNA cleavage
2013
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Precise and Ultrafast Molecular Sieving Through Graphene Oxide Membranes
2014 StandoutScienceNobel
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
Genomic Engineering and the Future of Medicine
2015 StandoutNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Arsenate Replacing Phosphate: Alternative Life Chemistries and Ion Promiscuity
2011
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Increased Replicative Fitness Can Lead to Decreased Drug Sensitivity of Hepatitis C Virus
2014 StandoutNobel
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Polyploidy in halophilic archaea: regulation, evolutionary advantages, and gene conversion
2019
Toward understanding phosphoseryl-tRNA Cys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase
2007 StandoutNobel
Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
2010
Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates
2012
Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class
1998
Resistance to Protease Inhibitors
2001
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor
1997
Works of Dea Slade being referenced
Identification of Macrodomain Proteins as Novel O-Acetyl-ADP-ribose Deacetylases
2011
Recombination and Replication in DNA Repair of Heavily Irradiated Deinococcus radiodurans
2009
Reassembly of shattered chromosomes in Deinococcus radiodurans
2006 Nature
Selective inhibition of divergent seryl‐tRNA synthetases by serine analogues
2005
The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase
2011 Nature
Involvement ofEscherichia coliDNA Polymerase IV in Tolerance of Cytotoxic Alkylating DNA Lesionsin Vivo
2007
Oxidative Stress Resistance inDeinococcus radiodurans
2011
Antiviral activity of the dihydropyrone PNU-140690, a new nonpeptidic human immunodeficiency virus protease inhibitor
1997
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation
2016
(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes
1996