Citation Impact
Citing Papers
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Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
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“Selective” serotonin 5-HT2A receptor antagonists
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Molecular, pharmacological and functional diversity of 5-HT receptors
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Structure and function of the blood–brain barrier
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5-HT7 Receptor Inhibition and Inactivation Induce Antidepressantlike Behavior and Sleep Pattern
2005
Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytrytamine7 receptor antagonist SB 269970
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Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT 2C receptors in Wistar rats
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Functional Selectivity and Classical Concepts of Quantitative Pharmacology
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Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
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A meta-analysis of 25 years of mood-creativity research: Hedonic tone, activation, or regulatory focus?
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2001
Network pharmacology: the next paradigm in drug discovery
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SB‐272183, a selective 5‐HT1A, 5‐HT1B and 5‐HT1D receptor antagonist in native tissue
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The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
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5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
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Sleep Homeostasis Modulates Hypocretin-Mediated Sleep-to-Wake Transitions
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RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms
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The Non-Antiemetic Uses of Serotonin 5-HT3 Receptor Antagonists
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A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment
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Constitutive Activity of the Serotonin2C Receptor InhibitsIn VivoDopamine Release in the Rat Striatum and Nucleus Accumbens
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SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist
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The Gerbil Elevated Plus-Maze I Behavioral Characterization and Pharmacological Validation
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The Selective Serotonin2A Receptor Antagonist, MDL100,907, Elicits a Specific Interoceptive Cue in Rats
2002
Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture
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Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
A Commentary on the Neurobiology of the Hypocretin/Orexin System
2001
Stress signalling pathways that impair prefrontal cortex structure and function
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A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats
2000
Stress and the brain: from adaptation to disease
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The elevated T-maze as an experimental model of anxiety
1998
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2001
Behavioural pharmacology of 5-HT3 receptor antagonists: a critical update on therapeutic potential
1993
Neurobiology of Depression
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Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens
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RS‐127445: a selective, high affinity, orally bioavailable 5‐HT2B receptor antagonist
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Evidence for a role for dopamine in the diazepam locomotor stimulating effect
1991
Orexin receptors as therapeutic drug targets
2012
Are subordinates always stressed? a comparative analysis of rank differences in cortisol levels among primates
2003
A review of central 5-HT receptors and their function
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Major Depressive Disorder
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The neural basis of psychedelic action
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RS-102221: A Novel High Affinity and Selective, 5-HT 2C Receptor Antagonist
1997
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
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BW 723C86, a 5-HT2B Receptor Agonist, Causes Hyperphagia and Reduced Grooming in Rats
1997
Orexin Receptor Antagonists: A New Concept In CNS Disorders?
2010
Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin
2002
Orexins and appetite regulation
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Hypoglycemia activates arousal-related neurons and increases wake time in adult rats
2007
Ghrelin: Structure and Function
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2004
Optogenetics in Neural Systems
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Anxiolytic-like Actions of the Selective 5-HT 4 Receptor Antagonists SB 204070A and SB 207266A in Rats
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An analysis of the attrition of drug candidates from four major pharmaceutical companies
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8-OH-DPAT-induced Spontaneous Tail-flicks in the Rat are Facilitated by the Selective Serotonin (5-HT) 2C Agonist, RO 60-0175: Blockade of its Actions by the Novel 5-HT 2C Receptor Antagonist SB 206,553
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Effects of the 5‐HT2B receptor agonist, BW 723C86, on three rat models of anxiety
1996
Involvement of 5-HT1A Receptors in Homeostatic and Stress-Induced Adaptive Regulations of Paradoxical Sleep: Studies in 5-HT1A Knock-Out Mice
2002
Novel 5-HT7Receptor Inverse Agonists. Synthesis and Molecular Modeling of Arylpiperazine- and 1,2,3,4-Tetrahydroisoquinoline-Based Arylsulfonamides
2004
Serotonin and the 5-HT2BReceptor in the Development of Enteric Neurons
2000
The effects of GABA and benzodiazepine receptor antagonists on the anti-conflict actions of diazepam or ethanol
1984
Anticonflict effect of the putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
1984 StandoutNobel
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
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Catalytic Staudinger/Aza‐Wittig Sequence by in situ Phosphane Oxide Reduction
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Phosphine Organocatalysis
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Nervous system distribution of the serotonin 5-HT3 receptor mRNA.
1993 StandoutNobel
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Control of Sleep and Wakefulness
2012
Rapid access to diverse α-carbolines through sequential transition metal catalyzed amination and direct C–H arylation
2014
Effect produced by acute and chronic administration of the selective 5‐HT3 receptor antagonist BRL 46470 on the number of spontaneously active midbrain dopamine cells in the rat
1994
Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience
2009
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
A new approach to the synthesis of functionalized pyrido[2,3-b]indoles by way of a palladium-catalyzed ring closing reaction between the N-1 and C-9a positions
1998
First Suzuki–Miyaura type cross-coupling of ortho-azidobromobenzene with arylboronic acids and its application to the synthesis of fused aromatic indole-heterocycles
2007
About Sleep's Role in Memory
2013 Standout
Therapeutic Potential of Serotonin 5-HT3 Antagonists in Neuropsychiatric Disorders
1995
Generation of a Set of Simple, Interpretable ADMET Rules of Thumb
2008
Anxiolytic-like action of the 3-PPP enantiomers in the Vogel conflict paradigm
1987 StandoutNobel
SB‐334867‐A: the first selective orexin‐1 receptor antagonist
2001
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
2009 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
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ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
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Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
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The Role of Hypocretins (Orexins) in Sleep Regulation and Narcolepsy
2002
A one-pot, four-component synthesis of α-carboline derivatives
2009
Serotonin receptor knockouts: A moody subject
1998 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
The Influence of Social Hierarchy on Primate Health
2005 StandoutScience
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
5-HT2AReceptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex
1997
AN INTEGRATIVE THEORY OF LOCUS COERULEUS-NOREPINEPHRINE FUNCTION: Adaptive Gain and Optimal Performance
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Hypocretin-1 Modulates Rapid Eye Movement Sleep through Activation of Locus Coeruleus Neurons
2000
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Reversal of the anti-conflict action of valproate by various GABA and benzodiazepine antagonists
1984
Works of D.C Piper being referenced
Characterization of SB‐269970‐A, a selective 5‐HT7 receptor antagonist
2000
Dose–response effects of orexin-A on food intake and the behavioural satiety sequence in rats
2000
Effect of SB-243213, a selective 5-HT2C receptor antagonist, on the rat sleep profile
2002
SB‐334867, a selective orexin‐1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin‐A in rats
2001
Clozapine enhances breakpoint in common marmosets responding on a progressive ratio schedule
2001
Chronic administration of the 5-HT3 receptor antagonist BRL 43694; effects on reflex epilepsy and social behaviour of the Mongolian gerbil
1990
Effect of SB 200646A, a 5-HT2C/5-HT2B receptor antagonist, in two conflict models of anxiety
1995
The novel brain neuropeptide, orexin‐A, modulates the sleep–wake cycle of rats
2000
Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat
2003
Marmoset Conspecific Confrontation: An Ethologically-Based Model of Anxiety
1997
BRL 46470A: a highly potent, selective and long acting 5-HT3 receptor antagonist with anxiolytic-like properties
1993
In vitroandin vivoprofile of SB 206553, a potent 5‐HT2C/5‐HT2Breceptor antagonist with anxiolytic‐like properties
1996
Effects of agents which enhance GABA-mediated neurotransmission on licking conflict in rats and exploration in mice
1982
Synthesis and potential anxiolytic activity of 4-amino-pyrido[2,3-b]indoles
1993