Standout Papers
Citation Impact
Citing Papers
HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
2015
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
2017
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
1989 StandoutNatureNobel
Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins
2015
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
2016
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
1988 StandoutNatureNobel
High‐Resolution N6‐Methyladenosine (m6A) Map Using Photo‐Crosslinking‐Assisted m6A Sequencing
2014
The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
2016
de FACTo Nucleosome Dynamics
2006
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Viral and cellular mRNA capping: Past and prospects
2000
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation
2015
Sequence specificity of the human mRNA N6-adenosine methylasein vitro
1990 StandoutNobel
m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination
2016 Nature
Context effects on N6-adenosine methylation sites in prolactin mRNA
1994
Antibody diversity: Somatic hypermutation of rearranged VH genes
1981
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
2012 Standout
Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
2015 Standout
Analysis andin vitrolocalization of internal methylated adenine residues in dihydrofolate reductase mRNA
1990
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Phage antibodies: filamentous phage displaying antibody variable domains
1990 StandoutNatureNobel
Yeast targets for mRNA methylation
2010
Elongation by RNA polymerase II: the short and long of it
2004
Induction of sporulation in Saccharomyces cerevisiae leads to the formation of N6-methyladenosine in mRNA: a potential mechanism for the activity of the IME4 gene
2002
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Post-transcriptional modifications of mRNA. Purification and characterization of cap I and cap II RNA (nucleoside-2'-)-methyltransferases from HeLa cells.
1981
Human immunoglobulin κ light-chain genes are deleted or rearranged in λ-producing B cells
1981 Nature
Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.
1981
Ca2+-stimulated ribonucleases from rat mammary gland and R3230AC mammary adenocarcinoma nuclei
1977
A Polynucleotide Segment Rich in Adenylic Acid in the Rapidly-Labeled Polyribosomal RNA Component of Mouse Sarcoma 180 Ascites Cells
1971
Somatic generation of antibody diversity.
1976 StandoutNobel
Fine mapping of an immunoglobulin gene activator.
1984
Methyl labeling of HeLa cell hnRNA: a comparison with mRNA
1976
Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus
1982 Nobel
Identification of precursor molecules to individual tRNA species from Bombyx mori.
1978 StandoutNobel
Analysis of the C-Value Paradox by Molecular Hybridization
1974 StandoutNobel
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
A labile inhibitor blocks immunoglobulin kappa-light-chain-gene transcription in a pre-B leukemic cell line.
1986
N6, O2′-dimethyladenosine a novel methylated ribonucleoside next to the 5′ terminal of animal cell and virus mRNAs
1975 Nature
Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis*
1967
Multiple Immunoglobulin Heavy-Chain Gene Transcripts in Abelson Murine Leukemia Virus-Transformed Lymphoid Cell Lines
1982 Nobel
Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends
1980
Identification and mapping of N6-methyladenosine containing sequences in Simian Virus 40 RNA
1979
Rapidly labeled HeLa cell nuclear RNA
1966
Why genes in pieces?
1978 StandoutNatureNobel
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene
1983 StandoutNobel
Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene
1982 Nature
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
1985 Nature
Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants
1977 StandoutNobel
Immunoglobulin light chain mRNA is processed from large nuclear RNA.
1978
Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain
1980 Nobel
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Identification of Methylated Nucleosides in Messenger RNA from Novikoff Hepatoma Cells
1974
N6-Methyladenosine Residues in an Intron-Specific Region of Prolactin Pre-mRNA
1990
Sequence specificity of mRNA N6-adenosine methyltransferase
1990
5'-Terminal and internal methylated nucleotide sequences in HeLa cell mRNA
1976
The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells
1978
Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μm and μs mRNA
1983
N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA
1979
Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain
1980
Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
1986 StandoutNobel
Organization, Transcription, and Regulation in the Animal Genome
1973
Precise Localization of m6A in Rous Sarcoma Virus RNA Reveals Clustering of Methylation Sites: Implications for RNA Processing
1985
The synthesis of protein(S) for chromosome condensation may be regulated by a post‐transcriptional mechanism
1981
Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells
1968
N6-methyladenosine residues in an intron-specific region of prolactin pre-mRNA.
1990
The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse.
1982 StandoutNobel
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification
1983 StandoutNatureNobel
Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes
1981 Nobel
Ribosomal RNA Synthesis and Processing in a Particulate Site in the HeLa Cell Nucleus
1966 Science
Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution
1986 Science
Modified nucleosides and bizarre 5′-termini in mouse myeloma mRNA
1975 Nature
Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.
1981
Spliced segments at the 5′ terminus of adenovirus 2 late mRNA
1977
Structure, sequence and expression of the hepatitis delta (δ) viral genome
1986 StandoutNatureNobel
Somatic mutation of immunoglobulin light-chain variable-region genes
1981
Blocked, methylated 5′-terminal sequence in avian sarcoma virus RNA
1975 StandoutNatureNobel
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments
1980
Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.
1977 Standout
Correct transcription of a cloned mouse immunoglobulin gene in vivo.
1983
Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum
1982 StandoutNatureNobel
Use of low concentrations of actinomycin D in the study of RNA synthesis in ehrlich ascites cells
1966
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes
1981 StandoutNatureNobel
An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA
1971
Antibody-nucleic acid complexes. Immunospecific recognition of 7-methylguanine- and N6-methyladenine-containing 5'-terminal oligonucleotides of mRNA.
1979
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes
1980 StandoutNatureNobel
Processing and function of undermethylated chicken embryo fibroblast mRNA.
1979
Human 7SL RNA consists of a 140 nucleotide middle-repetitive sequence inserted in an Alu sequence
1982
Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes
1966
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles
1983
Sequence specificity of internal methylation in B77 avian sarcoma virus RNA subunits
1977
Inhibition of methylation at two internal N6-methyladenosine sites caused by GAC to GAU mutations.
1987
Immunoglobulin gene transcription is activated by downstream sequence elements
1983 Nobel
Variation in the crossover point of kappa immunoglobulin gene V-J recombination: Evidence from a cryptic gene
1980
Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma
1980 Nature
Effect of undermethylation on mRNA cytoplasmic appearance and half-life
1984
HYBRIDIZATION PROPERTIES OF DNA SEQUENCES DIRECTING THE SYNTHESIS OF MESSENGER RNA AND HETEROGENEOUS NUCLEAR RNA
1971
Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes.
1981
An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development
1982
Repression of the Immunoglobulin Heavy Chain Enhancer by the Adenovirus-2 E1A Products
1985 Science
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes
1986 NatureNobel
Ordered rearrangement of immunoglobulin heavy chain variable region segments.
1984 StandoutNobel
Isopycnic Separation of Subcellular Components from Poliovirus-Infected and Normal HeLa Cells
1968 StandoutScienceNobel
The methylated constituents of globin mRNA
1975
Synthesis of two classes of small RNA species in vivo and in vitro
1977
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Methylated nucleotides block 5′ terminus of HeLa cell messenger RNA
1975
Methylations of adenosine residues (m6A) in pre-mRNA are important for formation of late simian virus 40 mRNAs
1983
A Protein of Molecular Weight 78,000 Bound to the Polyadenylate Region of Eukaryotic Messenger RNAs
1973 StandoutNobel
RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination
1977 Standout
Effect of undermethylation on mRNA cytoplasmic appearance and half-life.
1984
In vitro splicing of the ribosomal RNA precursor in nuclei of tetrahymena
1980 StandoutNobel
Relative occurrence of polyadenylic acid sequences in messenger and heterogeneous nuclear RNA of L cells as determined by poly (U)-hydroxylapatite chromatography
1972
In vivo splicing products of the rabbit β-globin pre-mRNA
1984
Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.
1982
Chance, necessity and antibody gene dynamics
1983 Nature
Methylation of nuclear simian virus 40 RNAs
1979
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification
2015
Variable and constant regions are separated in the 10-kbase transcription unit coding for immunoglobulin kappa light chains.
1978
Recombined flanks of the variable and joining segments of immunoglobulin genes.
1982
Transcriptional regulation of immunoglobulin V genes
1981
Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution
1975
A Particle Associated with the Polyadenylate Segment in Mammalian Messenger RNA
1972
Cloning and characterization of cDNA copies of the 7S RNAs of HeLa cells
1982
Transfer RNA in posterior silk gland of Bombyx mori: polyacrylamide gel mapping of mature transfer RNA, identification and partial structural characterization of major isoacceptor species
1977
Antibody nucleic acid complexes. Immunospecific retention of N6-methyladenosine-containing transfer ribonucleic acid
1978
Localization of N6-methyladenosine in the Rous sarcoma virus genome
1977
A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody
1981
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH
1980
Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses
1978 StandoutNobel
Evidence that all messenger RNA molecules (except histone messenger RNA) contain poly(A) sequences and that the poly(A) has a nuclear function
1972
Identification of a Selective Polymerase Enables Detection of N6-Methyladenosine in RNA
2013
Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.
1986
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 Standout
Histone mRNAs contain blocked and methylated 5′ terminal sequences but lack methylated nucleosides at internal positions
1977
Misalignment of V and J gene segments resulting in a nonfunctional immunoglobulin gene
1981
Messenger and Heterogeneous Nuclear RNA in HeLa Cells: Differential Inhibition by Cordycepin
1970 StandoutNobel
Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.
1983
Dual expression of λ genes in the MOPC-315 plasmacytoma
1981 NatureNobel
DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus.
1982
Polymorphism in anti-phosphocholine antibodies reflecting evolution of immunoglobulin families.
1983
RNA splicing mutation in an aberrantly rearranged immunoglobulin lambda I gene.
1981
The methylation state of poly A-containing-messenger RNA from cultured hamster cells
1975
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Expression of cloned imunoglobulin genes introduced into mouse L cells
1983 StandoutNobel
Nucleotide sequences at the N6-methyladenosine sites of HeLa cell messenger ribonucleic acid
1977
The scanning model for translation: an update.
1989 Standout
A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene
1984 Nature
MTA Is an Arabidopsis Messenger RNA Adenosine Methylase and Interacts with a Homolog of a Sex-Specific Splicing Factor
2008
Isolation of yeast histone genes H2A and H2B
1979 StandoutNobel
Two kappa immunoglobulin genes are expressed in the myeloma S107
1981
Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus
1975
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 Standout
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes
1983
Interaction of HeLa cell proteins with RNA
1970 StandoutNobel
Somatic generation of antibody diversity
1983 StandoutNatureNobel
Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.
1992 StandoutNobel
β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function
1990 StandoutScienceNobel
Small RNA species of the HeLa cell: Metabolism and subcellular localization
1976
The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.
1981
Sequences at the somatic recombination sites of immunoglobulin light-chain genes
1979 StandoutNatureNobel
Molecular distinction between fetal and adult forms of muscle acetylcholine receptor
1986 StandoutNatureNobel
Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
1984 Standout
The 5′-termini of heterogeneous nuclear RNA: a comparison among molecules of different sizes and ages
1977
Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression
1981 Nature
Content of N-6 methyl adenylic acid in heterogeneous nuclear and messenger RNA of HeLa cells
1977
Precise localization of m6A in Rous sarcoma virus RNA reveals clustering of methylation sites: implications for RNA processing.
1985
Restricted association of V and J-C gene segments for mouse lambda chains.
1984 StandoutNobel
Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome
1989 StandoutScienceNobel
Release, Identification, and Isolation of Messenger RNA from Mammalian Ribosomes
1971 StandoutNobel
Rat kappa-chain J-segment genes: Two recent gene duplications separate rat and mouse
1982
Works of Dawn E. Kelley being referenced
The joining of V and J gene segments creates antibody diversity
1980 Nature
CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin
1999
Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene
1981
The Relationship between hnRNA and mRNA
1977
Synthesis and turnover of nuclear and cytoplasmic polyadenylic acid in mouse L cells
1974
Functional significance and evolutionary development of the 5′-terminal regions of immunoglobulin variable-region genes
1982
Immunoglobulin messenger RNAs in murine cell lines that have characteristics of immature B lymphocytes
1979
Methylated constituents of heterogeneous nuclear RNA: Presence in blocked 5′ terminal structures
1975
Existence of methylated messenger RNA in mouse L cells
1974
Selective suppression of the transcription of ribosomal genes in mouse‐human hybrid cells
1979
Hybridization of Rapidly Labeled Nuclear Ribonucleic Acids
1964 Science
Persistent synthesis of 5S RNA when production of 28S and 18S ribosomal RNA is inhibited by low doses of actinomycin D
1968
Organization and expression of immunoglobulin genes in fetal liver hybridomas.
1981
The production of ribosomal RNA from high molecular weight precursors
1972
The production of ribosomal RNA from high molecular weight precursors
1971
Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein.
1991
Comparison of mRNA precursors in plasmacytomas producing closely related κ chains
1979
Buoyant densities of cytoplasmic ribonucleoprotein particles of mammalian cells: Distinctive character of ribosome subunits and the rapidly labeled components
1966
Evolution of the Transcription Unit of Ribosomal RNA
1970
Messenger RNA turnover in mouse L cells
1973
Comparison of methylated sequences in messenger RNA and heterogeneous nuclear RNA from mouse L cells
1977
Localization of polyadenylic acid sequences in messenger ribonucleic acid of mammalian cells
1972
The methylated constituents of L cell messenger RNA: Evidence for an unusual cluster at the 5′ terminus
1975
Polyadenylic acid sequences on 3' termini of vaccinia messenger ribonucleic acid and mammalian nuclear and messenger ribonucleic acid
1972
Lifetime of the messenger RNA's which code for ribosomal proteins in L-cells
1971
Kinetics of formation of 5′ terminal caps in mRNA
1976
Aberrant rearrangement of the κ light-chain locus involving the heavy-chain locus and chromosome 15 in a mouse plasmacytoma
1983 Nature
Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesis.
1985
Secondary structure maps of ribosomal RNA
1974
Transcription of mouse kappa chain genes: implications for allelic exclusion.
1980 StandoutNobel
On the lability of poly(A) sequences during extraction of messenger RNA from polyribosomes
1972
Messenger RNA-protein complexes and newly synthesized ribosomal subunits: Analysis of free particles and components of polyribosomes
1968
Inhibition of RNA synthesis by actinomycin D: Characteristic dose‐response of different RNA species
1970