Standout Papers
- Expression of hypoxia-inducible factor 1? in brain tumors (2000)
- Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell‐mediated expansion (2004)
- Expression of hypoxia‐inducible factor 1α in brain tumors (2000)
- Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis (2014)
- Stromal Cell–Derived Factor-1α and CXCR4 Expression in Hemangioblastoma and Clear Cell-Renal Cell Carcinoma: von Hippel-Lindau Loss-of-Function Induces Expression of a Ligand and Its Receptor (2005)
- Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B (2006)
- Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. (1999)
- Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF (1999)
- Molecular Events Implicated in Brain Tumor Angiogenesis and Invasion (2000)
Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
CXCR3 expression is associated with poor survival in breast cancer and promotes metastasis in a murine model
2009
Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity
2005
Hypoxia and Hypoxia-Inducible Factor-1 Expression Enhance Osteolytic Bone Metastases of Breast Cancer
2007
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer.
2000
Regulation of HIF prolyl hydroxylases by hypoxia‐inducible factors
2004
Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1alpha) expression in serous ovarian cancer: an immunohistochemical study
2008
Induction of ID2 Expression by Hypoxia-inducible Factor-1
2004
MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
2011 StandoutNobel
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
2005 StandoutNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer.
2002
Hallmarks of Cancer: The Next Generation
2011 Standout
HIFing the Brakes: Therapeutic Opportunities for Treatment of Human Malignancies
2006
Hypoxia-inducible factor-1α expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas
2006
Mouse Snail Is a Target Gene for HIF
2011
The role of hypoxia-inducible factors in tumorigenesis
2008
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients.
2002
The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
2000 StandoutNobel
Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
2001
Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance
2008
Inhibition of Hypoxia-Inducible Factor Is Sufficient for Growth Suppression of VHL−/− Tumors
2004
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
Association of hypoxia‐inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma
2002
Levels of hypoxia‐inducible factor‐1α independently predict prognosis in patients with lymph node negative breast carcinoma
2003 StandoutNobel
Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy.
2001
BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis
2001
Heterogeneity of the Tumor Vasculature
2010
Hypoxia-inducible factor 1α is closely linked to an aggressive phenotype in breast cancer
2007
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
2009 Standout
Pathways mediating VEGF-independent tumor angiogenesis
2009
Suppression of tumor growth through disruption of hypoxia-inducible transcription
2000 StandoutNobel
Involvement of Members of the Cadherin Superfamily in Cancer
2009
Hsp90 Regulates a von Hippel Lindau-independent Hypoxia-inducible Factor-1α-degradative Pathway
2002
Analysis of von Hippel—Lindau mutations with comparative genomic hybridization in sporadic and hereditary hemangioblastomas: possible genetic heterogeneity
2002
Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme
1994
The hypoxic response of tumors is dependent on their microenvironment
2003
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
2007
The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma
2002
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
HIF-1 and tumor progression: pathophysiology and therapeutics
2002 StandoutNobel
Evaluation of hypoxia‐inducible factor 1α overexpression as a predictor of tumour recurrence and progression in superficial urothelial bladder carcinoma
2005
Expression of Hypoxia‐Inducible Factor (HIF)‐1α and Vascular Endothelial Growth Factor (VEGF)‐D As Outcome Predictors in Resected Esophageal Squamous Cell Carcinoma
2008
Pathogenesis and clinical features of psoriasis
2007 Standout
HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo
2007 StandoutNobel
Effect of Antisense Hypoxia-inducible Factor 1?? on Progression, Metastasis, and Chemosensitivity of Pancreatic Cancer
2006
Targeting hypoxia cell signaling for cancer therapy
2007
Hypoxia‐inducible factor 1α/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis
2004
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
1999
Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia‐inducible factor 1
2006 StandoutNobel
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Significance of circulating endothelial progenitor cells in hepatocellular carcinoma†
2006
YC-1: A Potential Anticancer Drug Targeting Hypoxia-Inducible Factor 1
2003
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry
2010
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
2008
Increased levels of circulating endothelial progenitor cells and circulating endothelial nitric oxide synthase in patients with gliomas
2007
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes
2001
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Metastasis and stem cell pathways
2007
Overexpression of hypoxia-inducible factor HIF-1α predicts early relapse in breast cancer: Retrospective study in a series of 745 patients
2005
Altered Expression of Angiopoietins and Tie2 Endothelium Receptor in Psoriasis
2001
SEPT9_v1 Up-regulates Hypoxia-inducible Factor 1 by Preventing Its RACK1-mediated Degradation
2009
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
2012 StandoutNobel
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
1992 StandoutNature
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
Antiangiogenic therapy in malignant gliomas
2008
Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1
2006 StandoutNobel
Cellular abnormalities of blood vessels as targets in cancer
2004
Specialization of tumour vasculature
2002
Inhibition of angiogenesis and invasion in malignant gliomas
2007
Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis
1999
HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity
2007 StandoutNobel
Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
2014 Standout
Mechanisms of resistance to antiangiogenesis therapy
2010
Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma
2009
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
2007
Age-dependent Defect in Vascular Endothelial Growth Factor Expression Is Associated with Reduced Hypoxia-inducible Factor 1 Activity
2000 StandoutNobel
Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer
2002
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
2002 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
2003
Role of Hypoxia-Inducible Factor 1 in Gastric Cancer Cell Growth, Angiogenesis, and Vessel Maturation
2004 StandoutNobel
Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme
2009
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Glioblastoma‐derived tumorospheres identify a population of tumor stem‐like cells with angiogenic potential and enhanced multidrug resistance phenotype
2006
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Hypoxia-inducible Factor 1 Activation by Aerobic Glycolysis Implicates the Warburg Effect in Carcinogenesis
2002
Levels of Hypoxia-Inducible Factor-1 During Breast Carcinogenesis
2001 StandoutNobel
OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α
2005 StandoutNobel
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
EC5S Ubiquitin Complex Is Recruited by KSHV Latent Antigen LANA for Degradation of the VHL and p53 Tumor Suppressors
2006
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
2002
The p14ARF Tumor Suppressor Protein Facilitates Nucleolar Sequestration of Hypoxia-inducible Factor-1α (HIF-1α) and Inhibits HIF-1-mediated Transcription
2001
Advanced MRI of Adult Brain Tumors
2007
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
2003 Standout
Direct regulation of TWIST by HIF-1α promotes metastasis
2008
Invasion as limitation to anti-angiogenic glioma therapy
2003
Hypoxia signalling in cancer and approaches to enforce tumour regression
2006 Nature
Malignant Gliomas in Adults
2008 Standout
Angiogenesis in brain tumours
2007
Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology
2001 StandoutNobel
Differential prognostic impact of hypoxia induced and diffuse HIF-1α expression in invasive breast cancer
2005
Inhibiting kinases in malignant gliomas
2007
Expression of hypoxia-inducible factor-1α in oligodendrogliomas
2001
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Hypoxia: A key regulator of angiogenesis in cancer
2007
HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion
2008
Hypoxia-driven selection of the metastatic phenotype
2007
Hypoxia-Inducible Factor 1? Expression Correlates with Angiogenesis and Unfavorable Prognosis in Bladder Cancer
2004
Neurogenesis and the Cell Cycle
2003
Role of Id Proteins in Embryonic and Tumor Angiogenesis
2001
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Anti-VEGF Antibody Treatment of Glioblastoma Prolongs Survival But Results in Increased Vascular Cooption
2000
Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
2012
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Transduction pathways involved in Hypoxia-Inducible Factor-1 phosphorylation and activation
2001
Mechanisms of angiogenesis and arteriogenesis
2000 Standout
Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy
2006
Hypoxia, gene expression, and metastasis
2007
Antiangiogenic therapies for high-grade glioma
2009
Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene
2002
Significant correlation of hypoxia-inducible factor-1α with treatment outcome in cervical cancer treated with radical radiotherapy
2003
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
2002 StandoutNobel
Hypoxia inducible factor‐1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response
2005
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Evaluation of HIF-1 inhibitors as anticancer agents
2007 StandoutNobel
The role of hypoxia in recurrence following resection of Dukes’ B colorectal cancer
2008
Novel anti-angiogenic therapies for malignant gliomas
2008
Oxygen homeostasis
2009 StandoutNobel
Tumorigenesis and the angiogenic switch
2003 Standout
A Dialogue between the Hypoxia-Inducible Factor and the Tumor Microenvironment
2008
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
HIF-1: mediator of physiological and pathophysiological responses to hypoxia
2000 StandoutNobel
Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer.
2001 StandoutNobel
Life with Oxygen
2007 StandoutScienceNobel
ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis
2000
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Hypoxia, Clonal Selection, and the Role of HIF-1 in Tumor Progression
2000 StandoutNobel
Hypoxia-Inducible Factor-1α Is a Key Regulator of Metastasis in a Transgenic Model of Cancer Initiation and Progression
2007
Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2.
2001
Update on brain tumor imaging: from anatomy to physiology.
2006
Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell–mediated immunity via dendritic cells
2007 StandoutNobel
Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin
2002
Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.
2003 StandoutNobel
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Therapeutic Application of Noncytotoxic Molecular Targeted Therapy in Gliomas: Growth Factor Receptors and Angiogenesis Inhibitors
2008
von Hippel-Lindau Disease
2006 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha.
2000 StandoutNobel
Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation.
2001
Inhibiting Hypoxia-Inducible Factor 1 for Cancer Therapy
2006
Diagnosis and Treatment of Recurrent High-Grade Astrocytoma
2006
Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor—Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B
2007
Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function
2005
HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression
2001 StandoutNobel
A Potential α-Helix Motif in the Amino Terminus of LANA Encoded by Kaposi's Sarcoma-Associated Herpesvirus Is Critical for Nuclear Accumulation of HIF-1α in Normoxia
2007
Targeted Systemic Delivery of a Therapeutic siRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice
2009
Tumor and Host-Mediated Pathways of Resistance and Disease Progression in Response to Antiangiogenic Therapy
2009
Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
2002
Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy.
2001
Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
2000 StandoutNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
2013
Angiogenesis Ischemic and Neoplastic Disorders
2003 StandoutNobel
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Targeting tumors through the HIF system
2000 StandoutNobel
Biologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography
2002
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.
2000
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.
2003 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
2009
Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways.
2004
Hypoxia-Inducible Factor-1α Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer
2006
Nitric Oxide Is a Factor in the Stabilization of Hypoxia-Inducible Factor-1α in Cancer: Role of Free Radical Formation
2006
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.
2001
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
2007 StandoutNobel
Malignant glioma: genetics and biology of a grave matter
2001
The bioenergetic signature of cancer: a marker of tumor progression.
2002
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells
2012
Structural basis for Hif-1α/CBP recognition in the cellular hypoxic response
2002
Works of David Zagzag being referenced
Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging
2003
Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres
2010
Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B
2006 StandoutNobel
Angiogenesis in Gliomas: Imaging and Experimental Therapeutics
2005
Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell‐mediated expansion
2004 StandoutNobel
Glial Neoplasms: Dynamic Contrast-enhanced T2*-weighted MR Imaging
1999
Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells
1998
Molecular Events Implicated in Brain Tumor Angiogenesis and Invasion
2000 StandoutNobel
In Situ Expression of Angiopoietins in Astrocytomas Identifies Angiopoietin-2 as an Early Marker of Tumor Angiogenesis
1999
Low-Grade Gliomas: Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging—Prediction of Patient Clinical Response
2006
Angiogenesis in Gliomas: Biology and Molecular Pathophysiology
2005
High-grade glioma before and after treatment with radiation and Avastin: Initial observations
2008
Flavopiridol downregulates hypoxia-mediated hypoxia-induciblefactor-1α expression in human glioma cells by a proteasome-independentpathway: Implications for in vivo therapy
2005
Geldanamycin inhibits migration of glioma cells in vitro: A potential role for hypoxia‐inducible factor (HIF‐1α) in glioma cell invasion
2003
Vascular Apoptosis and Involution in Gliomas Precede Neovascularization: A Novel Concept for Glioma Growth and Angiogenesis
2000
Diffusion-Tensor MR Imaging of Intracranial Neoplasia and Associated Peritumoral Edema: Introduction of the Tumor Infiltration Index
2004
Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion
2006
Intracranial Mass Lesions: Dynamic Contrast-enhanced Susceptibility-weighted Echo-planar Perfusion MR Imaging
2002
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
1999 Nature
Flavopiridol inhibits the Growth of GL261 Gliomas In Vivo: Implications for Malignant Glioma Therapy
2004
Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF
1999 StandoutScience
Feasibility of Using Bevacizumab With Radiation Therapy in High Grade Gliomas
2007
Stromal Cell–Derived Factor-1α and CXCR4 Expression in Hemangioblastoma and Clear Cell-Renal Cell Carcinoma: von Hippel-Lindau Loss-of-Function Induces Expression of a Ligand and Its Receptor
2005 StandoutNobel
Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade.
2004
Expression of hypoxia‐inducible factor 1α in brain tumors
2000 StandoutNobel
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival
2008
Assessing global invasion of newly diagnosed glial tumors with whole-brain proton MR spectroscopy.
2005
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
2011
Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.
1990
Bevacizumab therapy in recurrent high grade glioma: Impact on local control and survival
2008
Comparing perfusion metrics obtained from a single compartment versus pharmacokinetic modeling methods using dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade.
2006
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases.
1999 StandoutNobel
Demyelinating Disease Versus Tumor in Surgical Neuropathology
1993
Immunohistochemical localization of basic fibroblast growth factor in astrocytomas.
1990
Expression of hypoxia-inducible factor 1? in brain tumors
2000 StandoutNobel
Dynamic contrast-enhanced perfusion MR imaging measurements of endothelial permeability: differentiation between atypical and typical meningiomas.
2003