Citation Impact

Citing Papers

Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes
2007
The Formulation of Rational Choice
1994 StandoutNobel
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Hepatic triacylglycerol accumulation and insulin resistance
2008
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
1995 Standout
Control of ureogenesis
1985
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Hepatic Very Low Density Lipoprotein-ApoB Overproduction Is Associated with Attenuated Hepatic Insulin Signaling and Overexpression of Protein-tyrosine Phosphatase 1B in a Fructose-fed Hamster Model of Insulin Resistance
2002
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
2003
mTOR Signaling in Growth Control and Disease
2012 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Insect Fat Body: Energy, Metabolism, and Regulation
2009 Standout
Intracellular Assembly of VLDL
2000
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Nonfasting Triglycerides and Risk of Myocardial Infarction, Ischemic Heart Disease, and Death in Men and Women
2007 Standout
Autophagy regulates lipid metabolism
2009 StandoutNature
The metabolic syndrome
2010 Standout
YMR313c/TGL3 Encodes a Novel Triacylglycerol Lipase Located in Lipid Particles of Saccharomyces cerevisiae
2003
Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion
1994
The Epicurean Fly: Using Drosophila Melanogaster to Study Metabolism
2009
Very-low-density lipoprotein assembly and secretion
2001
Metabolic origins and clinical significance of LDL heterogeneity
2002
Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism
2008
Autophagy: Renovation of Cells and Tissues
2011 Standout
Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans.
1995
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Lipid droplets as dynamic organelles connecting storage and efflux of lipids
2008
Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway
2000 StandoutNobel
Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice
2010
Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
1998 StandoutNobel
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis
2009
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
2009
Severity of Nonalcoholic Fatty Liver Disease and Progression to Cirrhosis Are Associated With Atherogenic Lipoprotein Profile
2014
The metabolic syndrome
2005 Standout
Non-alcoholic fatty liver disease
2021 Standout
Phospholipid methylation in mammals: from biochemistry to physiological function
2013
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
2005 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
2008
Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance
1999
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Autophagy in Human Health and Disease
2013 Standout
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
Activation of PPARα lowers synthesis and concentration of cholesterol by reduction of nuclear SREBP-2
2006
Arylacetamide deacetylase: A novel host factor with important roles in the lipolysis of cellular triacylglycerol stores, VLDL assembly and HCV production
2013 StandoutNobel
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
“New” hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
2005
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
2008
Autophagy and Aging
2011 Standout
The metabolic effects of tumor necrosis factor and other cytokines
1991
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Ubiquitin gene expression is increased in skeletal muscle of tumour‐bearing rats
1994
Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B–containing lipoproteins
2008 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
2009 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Dissecting differential gene expression within the circadian neuronal circuit of Drosophila
2009 StandoutNobel
The PI3K Pathway in Human Disease
2017 Standout
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation
2009
The nature of the growth pattern and of the metabolic response to fasting in the rat are dependent upon the dietary protein and folic acid intakes of their pregnant dams and post-weaning fat consumption
2007
Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes
1996
Role of Fat Body Lipogenesis in Protection against the Effects of Caloric Overload in Drosophila
2013
Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 StandoutNobel
New insights in the pathogenesis of non-alcoholic fatty liver disease
2006
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
Replication of hepatitis C virus
2007 StandoutNobel
MEK–ERK Inhibition Corrects the Defect in VLDL Assembly in HepG2 Cells
2006
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Cellular Determinants of Hepatitis C Virus Assembly, Maturation, Degradation, and Secretion
2007
Hepatitis C virus: viral proteins on the move
2009
Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport
2011
A Role of the Bile Salt Receptor FXR in Atherosclerosis
2010
Lumenal Lipid Metabolism
2012
Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase—Mediated Event
2001
11. Reasons and Persons
1986 Standout
Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers
2013 StandoutNobel
Targeting Fatty Acid Synthase in Breast and Endometrial Cancer: An Alternative to Selective Estrogen Receptor Modulators?
2006
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
1997 StandoutNobel
Thyroid Hormone Regulation of Metabolism
2014 Standout
Biosynthesis of Apolipoprotein B48-containing Lipoproteins
1996 StandoutNobel
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
2013 StandoutNobel
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
curledEncodes the Drosophila Homolog of the Vertebrate Circadian Deadenylase Nocturnin
2009
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
2004 StandoutScience
Autophagy and Metabolism
2010 StandoutScience
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
2007

Works of David Wiggins being referenced

Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice
2003
Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose
1999
The Concern to Survive
1979
Intracellular triacylglycerol lipase: Its role in the assembly of hepatic very-low-density lipoprotein (VLDL)
1995
Specialized hepatocyte-like cells regulate Drosophila lipid metabolism
2006 Nature
Decreased sensitivity to the inhibitory effect of insulin on the secretion of very—low-density lipoprotein in cultured hepatocytes from fructose-fed rats
1995
A role for PPARα in the control of SREBP activity and lipid synthesis in the liver
2005
Comparative effects of tumour necrosis factor-α (cachectin), interleukin-1-β and tumour growth on amino acid metabolism in the rat in vivo. Absorption and tissue uptake of α-amino[1-14C]isobutyrate
1989
Disturbances in the normal regulation of SREBP-sensitive genes in PPARα-deficient mice
2001
The intracellular triacylglycerol/fatty acid cycle: a comparison of its activity in hepatocytes which secrete exclusively apolipoprotein (apo) B100 very-low-density lipoprotein (VLDL) and in those which secrete predominantly apoB48 VLDL
1998
Synthesis and function of hepatic very-low-density lipoprotein
2004
Essentialism, continuity, and identity
1974
Origin of hepatic very-low-density lipoprotein triacylglycerol: the contribution of cellular phospholipid
1996
The lipolysis/esterification cycle of hepatic triacylglycerol. Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureas
1992
VLDL output by hepatocytes from obese Zucker rats is resistant to the inhibitory effect of insulin
1995
The roles of insulin and fatty acids in the regulation of hepatic very-low-density lipoprotein assembly.
2002
Identity, designation, essentialism and physicalism
1975
Is N-acetylglutamate a short-term regulator of urea synthesis?
1984
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis
2005
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2026