Citation Impact
Citing Papers
Why highly expressed proteins evolve slowly
2005 StandoutNobel
A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules
2003 StandoutScience
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
2007 StandoutScience
Nature of the protein universe
2009 StandoutNobel
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
Genome Evolution at the Genus Level: Comparison of Three Complete Genomes of Hyperthermophilic Archaea
2001
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Intrinsic evolutionary constraints on protease structure, enzyme acylation, and the identity of the catalytic triad
2013
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi
2002 StandoutScience
Metagenomic Analysis of the Human Distal Gut Microbiome
2006 StandoutScience
A census of protein repeats
1999
The COG database: an updated version includes eukaryotes
2003 Standout
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Genome trees constructed using five different approaches suggest new major bacterial clades
2001
MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
2011 Standout
Comparative genomics of Archaea: how much have we learned in six years, and what's next?
2003
Genome Sequence and Comparative Analysis of the Solvent-Producing BacteriumClostridium acetobutylicum
2001
Robustness against mutations in genetic networks of yeast
2000
Estimating the number of protein folds and families from complete genome data 1 1Edited by J. Thornton
2000
A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis
2002
Lateral gene transfer and the nature of bacterial innovation
2000 StandoutNature
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Lethality and centrality in protein networks
2001 StandoutNature
Genome sequences: Genome sequence of a model prokaryote
1997
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
Did DNA replication evolve twice independently?
1999
Genomics: Re-evaluation of translation machinery evolution
1998
Rickettsiae and Chlamydiae: evidence of horizontal gene transfer and gene exchange
1999
Automated genome sequence analysis and annotation.
1999
The genome sequence of Rickettsia prowazekii and the origin of mitochondria
1998 StandoutNature
Beyond complete genomes: from sequence to structure and function
1998
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Tailoring new enzyme functions by rational redesign
2000
Gene Ontology: tool for the unification of biology
2000 Standout
Evolutionary genomics: Thermotoga heats up lateral gene transfer
1999
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae
2000
A phylogenomic approach to microbial evolution
2001
Gene and context: Integrative approaches to genome analysis
2000
Large-Scale Taxonomic Profiling of Eukaryotic Model Organisms: A Comparison of Orthologous Proteins Encoded by the Human, Fly, Nematode, and Yeast Genomes
1998
Archaeal genomics
1999
Prokaryotic Evolution in Light of Gene Transfer
2002
Protein fold recognition using sequence profiles and its application in structural genomics
2000
Towards understanding the first genome sequence of a crenarchaeon by genome annotation using clusters of orthologous groups of proteins (COGs)
2000
Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes
2003
RNA silencing in plants
2004 StandoutNature
MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0
2007 Standout
Protein sequence similarity searches using patterns as seeds
1998
Analysis of Phenetic Trees Based on Metabolic Capabilites Across the Three Domains of Life
2004
The COG database: a tool for genome-scale analysis of protein functions and evolution
2000 Standout
The structure of the protein universe and genome evolution
2002 Nature
Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in Bacteria
2002
Broad phylogenomic sampling improves resolution of the animal tree of life
2008 StandoutNature
Genome Evolution at the Genus Level: Comparison of Three Complete Genomes of Hyperthermophilic Archaea
2001
Functional and structural genomics using PEDANT
2001
Comparative assessment of large-scale data sets of protein–protein interactions
2002 StandoutNature
Lineage-Specific Gene Expansions in Bacterial and Archaeal Genomes
2001
Construction and analysis of bacterial artificial chromosome libraries from a marine microbial assemblage
2000
Catalytic promiscuity and the evolution of new enzymatic activities
1999
Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes
2009
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Monophyly of class I aminoacyl tRNA synthetase, USPA, ETFP, photolyase, and PP‐ATPase nucleotide‐binding domains: implications for protein evolution in the RNA world
2002
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases
2003
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
2004 StandoutNature
Community structure and metabolism through reconstruction of microbial genomes from the environment
2004 StandoutNature
The Impact of Comparative Genomics on Our Understanding of Evolution
2000
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Growth of novel protein structural data
2007 StandoutNobel
Evolution of Aminoacyl-tRNA Synthetases—Analysis of Unique Domain Architectures and Phylogenetic Trees Reveals a Complex History of Horizontal Gene Transfer Events
1999
Lineage-specific loss and divergence of functionally linked genes in eukaryotes
2000
Constant relative rate of protein evolution and detection of functional diversification among bacterial, archaeal and eukaryotic proteins
2001
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Design and STM Investigation of Intramolecular Folding in Self-Assembled Monolayers on the Surface
2004 StandoutNobel
Lineage-Specific Gene Expansions in Bacterial and Archaeal Genomes
2001
Bioinformatics software for biologists in the genomics era
2007
Comparative Genomics of the Archaea (Euryarchaeota): Evolution of Conserved Protein Families, the Stable Core, and the Variable Shell
1999
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Life with 6000 Genes
1996 StandoutScience
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Decoupling function and taxonomy in the global ocean microbiome
2016 StandoutScience
Comparison of the Complete Protein Sets of Worm and Yeast: Orthology and Divergence
1998 Science
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Plants, animals and the logic of development
1999
CRISPR/Cas, the Immune System of Bacteria and Archaea
2010 StandoutScience
Arabidopsis Transcription Factors: Genome-Wide Comparative Analysis Among Eukaryotes
2000 StandoutScience
Divergent Evolution of Enzymatic Function: Mechanistically Diverse Superfamilies and Functionally Distinct Suprafamilies
2001
Autoproteolysis in nucleoporin biogenesis
1999 StandoutNobel
The Microbial Engines That Drive Earth's Biogeochemical Cycles
2008 StandoutScience
Systems biology of cyanobacterial secondary metabolite production and its role in drug discovery
2008
Measuring genome evolution
1998
Horizontal Gene Transfer in Prokaryotes: Quantification and Classification
2001
A Genomic Perspective on Protein Families
1997 StandoutScience
Toward understanding phosphoseryl-tRNA Cys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase
2007 StandoutNobel
Genome of the Extremely Radiation-Resistant Bacterium Deinococcus radiodurans Viewed from the Perspective of Comparative Genomics
2001
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of David Walker being referenced
SEALS: a system for easy analysis of lots of sequences.
1997
Comparison of archaeal and bacterial genomes: computer analysis of protein sequences predicts novel functions and suggests a chimeric origin for the archaea
1997
Analogous Enzymes: Independent Inventions in Enzyme Evolution
1998
Reply
1999
Evidence for massive gene exchange between archaeal and bacterial hyperthermophiles
1999