Citation Impact
Citing Papers
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity
2007 StandoutNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Peptide Environment of the Peptidyl Transferase Center from Escherichia coli 70 S Ribosomes as Determined by Thermoaffinity Labeling with Dihydrospiramycin
1995
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
Biochemical and kinetic characteristics of the interaction of the antitumor antibiotic sparsomycin with prokaryotic and eukaryotic ribosomes
1991
Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA
1988 Nature
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Novel Roles for Classical Factors at the Interface between Translation Termination and Initiation
1999
The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome
2003
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits
2002 StandoutNobel
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
2000 StandoutNatureNobel
A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre
1999
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
Ribozyme-catalysed amino-acid transfer reactions
1996 StandoutNatureNobel
EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome.
1999 StandoutNobel
Ribosome-inactivating proteins from plants
1993
Large-Scale Movement of Elongation Factor G and Extensive Conformational Change of the Ribosome during Translocation
2000
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
Binding sites of the antibiotics pactamycin and celesticetin on ribosomal RNAs
1991
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA
1992 StandoutNatureNobel
High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
2001 StandoutNobel
Structure of viscotoxin A3: disulfide location from weak SAD data
2003
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
2007
Mutations in the Peptidyl Transferase Center of 23 S rRNA Reveal the Site of Action of Sparsomycin, a Universal Inhibitor of Translation
1996
The hybrid state of tRNA binding is an authentic translation elongation intermediate
2006
A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome
1995 Nature
Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome
1997
Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
2000 StandoutNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance
1998
Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA
1987
Movement of the 3′‐end of tRNA through the peptidyl transferase centre and its inhibition by antibiotics
1997
A short history ofSHELX
2007 Standout
A cryo-electron microscopic study of ribosome-bound termination factor RF2
2003 StandoutNatureNobel
Puromycin–rRNA interaction sites at the peptidyl transferase center
2000
Mechanism of action of sparsomycin in protein synthesis
1992
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit
1999 StandoutNatureNobel
An Elongation Factor G-Induced Ribosome Rearrangement Precedes tRNA-mRNA Translocation
2003
Comparative Biochemistry and Biophysics of Ribosomal Proteins
1991
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
2009 StandoutNobel
Ribosomal crystallography: Peptide bond formation and its inhibition
2003 StandoutNobel
Solution conformation of methylated macrolide antibiotics roxithromycin and erythromycin using NMR and molecular modelling. Ribosome-bound conformation determined by TRNOE and formation of cytochrome P450-metabolite complex
1998
The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit
2000 StandoutNobel
Conformational Changes of the Small Ribosomal Subunit During Elongation Factor G-dependent tRNA–mRNA Translocation
2004
Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
2003 StandoutNobel
The Elongation Phase of Protein Synthesis
1996
Homoharringtonine
2001
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Ribosomal antibiotics: structural basis for resistance, synergism and selectivity
2004 StandoutNobel
Three-dimensional NMR spectroscopy of a protein in solution
1988 StandoutNatureNobel
Structural Basis of the Ribosomal Machinery for Peptide Bond Formation, Translocation, and Nascent Chain Progression
2003 StandoutNobel
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
The synthesis of polyphenylalanine on ribosomes to which erythromycin is bound
1991
Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template
2004 StandoutNatureNobel
Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms 1 1Edited by D. E. Draper
1999
The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus
1996 StandoutNobel
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
Chemical, biochemical and genetic endeavours characterizing the interaction of sparsomycin with the ribosome
1991
Elongating ribosomes in vivo are refractory to erythromycin
1987
The antibiotic viomycin traps the ribosome in an intermediate state of translocation
2007
Interaction of the antibiotics clindamycin and lincomycin withEscherichia coli23S ribosomal RNA
1992
Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome
1997 Nature
Rapid Kinetic Analysis of EF-G-dependent mRNA Translocation in the Ribosome
2003
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates
2004
Inhibition by Siomycin and Thiostrepton of Both Aminoacyl-tRNA and Factor G Binding to Ribosomes
1971
Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes ofEscherichia coli
1984
The conformations of the macrolide antibiotics erythromycin A, azithromycin and clarithromycin in aqueous solution: a 1H NMR study †
2000
Identification of Functionally Important Amino Acids of Ribosomal Protein L3 by Saturation Mutagenesis
2005
Nascent polypeptide chains emerge from the exit domain of the large ribosomal subunit: immune mapping of the nascent chain.
1982
Identification of the Chloramphenicol-Binding Protein in Escherichia coli Ribosomes by Partial Reconstitution
1973
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Kinetic aspects of tetracycline action on the acceptor (A) site of Escherichia coli ribosomes
1982
Lasting damage to bacterial ribosomes by reversibly bound virginiamycin M.
1980
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes
1971
Chemical Cross‐Linking of Elongation Factor G to both Subunits of the 70‐S Ribosomes from Escherichia coli
1982
Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes
1978
Migration of 40 S ribosomal subunits on messenger RNA when initiation is perturbed by lowering magnesium or adding drugs.
1979
Crystal Structure of an Initiation Factor Bound to the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Formation of a functional ribosome-membrane junction during translocation requires the participation of a GTP-binding protein.
1986
STUDIES ON THE FORMATION OF TRANSFER RIBONUCLEIC ACID-RIBOSOME COMPLEXES, XI. ANTIBIOTIC EFFECTS ON PHENYLALANYL-OLIGONUCLEOTIDE BINDING TO RIBOSOMES
1969
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Structural basis for inhibition of protein synthesis by the aminoacyl‐aminohexosyl‐cytosine group of antibiotics
1974
Affinities of tRNA binding sites of ribosomes from Escherichia coli
1986
Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome
1996 StandoutScienceNobel
Comparative Analysis of the Effect of Aminoglycosides on Bacterial Protein Synthesis in vitro
1979
Interaction between the erythromycin and chloramphenicol binding sites on the Escherichia coli ribosome
1977
GTP and methionine bristles
1989 StandoutNatureNobel
Chloramphenicol-erythromycin resistance mutations in a 23S rRNA gene of Escherichia coli
1985
Chicken liver ribosomes: Characterization of cross-reaction and inhibition of some functions by antibodies prepared against Escherichia coli ribosomal proteins L7 and L12
1976
Tetracycline can inhibit tRNA binding to the ribosomal P site as well as to the A site
1986
Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium
1994
Direct experimental evidence for kinetic proofreading in amino acylation of tRNAIle.
1976 StandoutNobel
Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis
1984
[28] The use of inhibitors in studies of protein synthesis
1974
Studies on the catalytic rate constant of ribosomal peptidyltransferase
1987
23S Ribosomal RNA mutations in halobacteria conferring resistance to the anti-80S ribosome targeted antibiotic anisomycin
1987
Interaction of a limited set of proteins with different mRNAs and protection of 5′-caps against pyrophosphatase digestion in initiation complexes
1979
Distance moved by transfer RNA during translocation from the A site to the P site on the ribosome
1982
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Peptide‐mediated macrolide resistance reveals possible specific interactions in the nascent peptide exit tunnel
2004
MSI and MSII made on Ribosome in Idling Step of Protein Synthesis
1972 StandoutNatureNobel
Requirement of an Escherichia coli 50 S Ribosomal Protein Component for Effective Interaction of the Ribosome with T and G Factors and with Guanosine Triphosphate
1972
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
Inhibitors of protein synthesis
1974
Crystal and molecular structure of the antiobiotic blasticidin S hydrochloride pentahydrate
1981
Inhibition of ribosomal peptidyltransferase by chloramphenicol. Kinetic studies
1987
Affinity labeling of the ribonucleic acid component adjacent to the peptidyl recognition center of peptidyl transferase in Escherichia coli ribosomes
1975
Interaction of antibiotics with functional sites in 16S ribosomal RNA
1987 Nature
Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes
1972
GTPase Activation of Elongation Factors Tu and G on the Ribosome
2002
Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA.
1991
Erythromycin resistance by ribosome modification
1995
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.
1979 Standout
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
A Tunnel in the Large Ribosomal Subunit Revealed by Three-Dimensional Image Reconstruction
1987 StandoutScienceNobel
Hydrolysis of fMet-tRNA by Peptidyl Transferase
1971
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
The role of guanosine 5′-triphosphate in polypeptide chain elongation
1978
The action of virginiamycin M on the acceptor, donor, and catalytic sites of peptidyltransferase.
1984
Photo-affinity labelling at the peptidyl transferase centre reveals two different positions for the A- and P-sites in domain V of 23S rRNA.
1988
Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome
1999
Nuclear magnetic resonance study of the solution structure of α1-purothionin
1987
The Mode of Action of Pleuromutilin Derivatives
1975
The scanning model for translation: an update.
1989 Standout
The Requirement for Ribosomal Proteins L7 and L12 in Peptide-Chain Termination
1974
Ribosomal protein L1 from Escherichia coli. Its role in the binding of tRNA to the ribosome and in elongation factor g-dependent gtp hydrolysis.
1983
Studies on Transfer Ribonucleic Acid-Ribosome Complexes
1972
Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes
1999
Dual Interference of Hygromycin B with Ribosomal Translocation and with Aminoacyl-tRNA Recognition
1978
Site of action of a ribosomal RNA methylase responsible for resistance to erythromycin and other antibiotics.
1983
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Works of David Vázquez being referenced
Reconstitution of the 50 S ribosome subunit. Localization of activities related to the peptidyl transferase centre
1971
Ribosomal translocation promoted by guanylylimido diphosphate and guanylyl‐methylene diphosphonate
1975
Cooperative and Antagonistic Interactions of Peptidyl‐tRNA and Antibiotics with Bacterial Ribosomes
1977
Inhibition of ribosomal translocation by aminoglycoside antibiotics
1978
Ribosome Inactivation by the Toxic Lectins Abrin and Ricin
1975
Initiation of Translation with Native 40-S Ribosomal Subunits
1978
Inhibition by Aminoacyl Transfer Ribonucleic Acid of Elongation Factor G-dependent Binding of Guanosine Nucleotide to Ribosomes
1973
Inhibition of Translation in Eukaryotic Systems by Harringtonine
1977
Inhibition by Elongation Factor EF G of Aminoacyl-tRNA Binding to Ribosomes
1972
QUANTITATIVE BINDING OF 14C-ERYTHROMYCIN A TO E. COLI RIBOSOMES
1973
Synergistic Interaction of the Streptogramins with the Ribosome
1977
The Involvement of Sulphydryl Groups in the Peptidyl Transferase Centre of Eukaryotic Ribosomes
1975
Substrate‐and Antibiotic‐Binding Sites at the Peptidyl‐Transferase Centre of Escherichia coli Ribosomes
1971
Peptidyl Transferase Center of Rat-Liver Ribosome Cores
1977
Effects of Cations, Antibiotics and Other Agents on the Turnover of Guanosine‐Nucleotide · Elongation‐Factor‐G · Ribosome Complexes
1977
Action of Sparsomycin on Ribosome-catalysed Peptidyl Transfer
1969 Nature
Ribosomal activities dependent on elongation factors T and G. Effects of methanol
1973
Structure-activity relationships of sparsomycin and its analogs. Inhibition of peptide bond formation in cell-free systems and of L1210 and bacterial cell growth
1987
[3H]anisomycin binding to eukaryotic ribosomes
1974
Failure of fusidic acid and siomycin to block ribosomes in the pretranslocated state
1972
Specific Inhibition of Translocation by Tubulosine in Eukaryotic Polysomes
1976
The Stoichiometry of Ribosomal Translocation
1973
Elongation Factor T-Dependent Hydrolysis of Guanosine Triphosphate Resistant to Thiostrepton
1972
Initiation of the Polypeptide Chain by Reticulocyte Cell‐Free Systems
1976
Quantitative Binding of Antibiotics to Ribosomes from a Yeast Mutant Altered on the Peptidyl‐Transferase Center
1975
Enzymic and nonenzymic translocation by yeast polysomes. Site of action of a number of inhibitors
1977
Ribosomes, G-factor and Siomycin
1971
Thionins: Plant Peptides that Modify Membrane Permeability in Cultured Mammalian Cells
1981
Bruceantin, a novel inhibitor of peptide bond formation
1978
SURVEY OF INHIBITORS IN DIFFERENT STEPS OF PROTEIN SYNTHESIS BY MAMMALIAN RIBOSOMES
1972
Activities of Protein‐Deficient Particles Derived from 50‐S Ribosomal Subunits by NH4Cl/Ethanol Treatment
1976
Polypeptide‐Chain Elongation Promoted by Guanyl‐5′‐yl Imidodiphosphate
1976
Kinetic studies of peptide bond formation. Effect of chloramphenicol
1973
[G-3H] Gougerotin Binding to Ribosomes. Heterogeneity of Eukaryotic Ribosomes
1974
Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutants
1975
Functional interaction of neomycin B and related antibiotics with 30S and 50S ribosomal subunits
1979
Binding of puromycin to E. coli ribosomes. Effects of puromycin analogues and peptide bond formation inhibitors
1973
Inhibitory Effects of ‘Cap’ Analogues on Globin mRNA and Encephalomyocarditis RNA Translation in a Reticulocyte Cell‐Free System
1980
Peptidyl Transferase of Bacterial Ribosome: Resistance to Proteinase K
1979
The Interaction of Fusidic Acid with Peptidyl‐Transfer‐Ribonucleic‐Acid · Ribosome Complexes
1975
Dissociation of guanosine nucleotide.cntdot.elongation factor G.cntdot.ribosome complexes
1979
The Inhibition of Ribosomal Translocation by Viomycin
1977
Molecular mechanisms of antibiotic action on protein biosynthesis and membranes : Proceedings of a symposium held at the University of Granada (Spain) June 1st-4th, 1971
1972