Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Supramolecular structure of the Shigella type III secretion machinery: the needle part is changeable in length and essential for delivery of effectors
2000
Evidence that direct binding of Gβγ to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation
1995
Molecular Cloning and Characterization of a Novel p38 Mitogen-activated Protein Kinase
1997
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Cloning and Expression of a G Protein‐Linked Acetylcholine Receptor from Caenorhabditis elegans
1999
Ion conduction pore is conserved among potassium channels
2001 Nature
Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death
2002
X-ray structure of a voltage-dependent K+ channel
2003 StandoutNatureNobel
Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization
2000
Functional Analysis of the weaver Mutant GIRK2 K+ Channel and Rescue of weaver Granule Cells
1996
Evidence for a Functional Interaction between Integrins and G Protein-activated Inward Rectifier K+ Channels
1998
μ and δ Opioid Receptors Are Differentially Desensitized by the Coexpression of β-Adrenergic Receptor Kinase 2 and β-Arrestin 2 in Xenopus Oocytes
1997
Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
1994 StandoutNatureNobel
Cloning and Functional Characterization of a Novel ATP-sensitive Potassium Channel Ubiquitously Expressed in Rat Tissues, including Pancreatic Islets, Pituitary, Skeletal Muscle, and Heart
1995
Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development
1998
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
A Gene in the Pseudomonas syringae pv. tomato Hrp Pathogenicity Island Conserved Effector Locus, hopPtoA1, Contributes to Efficient Formation of Bacterial Colonies in Planta and Is Duplicated Elsewhere in the Genome
2002
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
1999
Structural Basis of Inward Rectification
2002 StandoutNobel
A Novel Human STE20-related Protein Kinase, HGK, That Specifically Activates the c-Jun N-terminal Kinase Signaling Pathway
1999
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
1998
Interaction Sites of the G Protein β Subunit with Brain G Protein-coupled Inward Rectifier K+ Channel
2001
Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gβγ
1998 Nature
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
1997
Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+channel
1994 StandoutNatureNobel
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Functional Effects of the Mouse weaver Mutation on G Protein–Gated Inwardly Rectifying K+ Channels
1996
A region of the muscarinic-gated atrial K+ channel critical for activation by G protein βγ subunits
1994
MEK Kinase 3 Directly Activates MKK6 and MKK7, Specific Activators of the p38 and c-Jun NH2-terminal Kinases
1999
Plant pathogens and integrated defence responses to infection
2001 StandoutNature
Cell Cycle Control by an Essential Bacterial Two-Component Signal Transduction Protein
1996
The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins
1995 Nature
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Identification of a Gene Encoding a Hyperpolarization-Activated Pacemaker Channel of Brain
1998 StandoutNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
In vivo antigen delivery by aSalmonella typhimurium type III secretion system for therapeutic cancer vaccines
2006
Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0
2007
Gβγ Binds Directly to the G Protein-gated K+ Channel, IKACh
1995
Induction of endogenous channels by high levels of heterologous membrane proteins in Xenopus oocytes
1995
Mammalian MAP kinase signalling cascades
2001 StandoutNature
JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
1999
Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction
1998
Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel
2001
The Molecular and Cellular Biology of HER2/neu Gene Amplification/Overexpression and the Clinical Development of Herceptin (Trastuzumab) Therapy for Breast Cancer
2000
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor
1999
Determination of the subunit stoichiometry of an inwardly rectifying potassium channel
1995
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
The RNA chaperone Hfq is essential for the virulence of Salmonella typhimurium
2006
Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel
1995
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
The plant immune system
2006 StandoutNature
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2
1998 Nature
Activation of Stress-activated Protein Kinases/c-Jun N-terminal Protein Kinases (SAPKs/JNKs) by a Novel Mitogen-activated Protein Kinase Kinase (MKK7)
1997
Function and structure of voltage‐dependent potassium channels
1994
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
1999
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.
1996
Reconstitution of I KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor
1995 StandoutScience
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum
2000 StandoutNobel
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response
2000 StandoutNobel
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
INWARD RECTIFIER POTASSIUM CHANNELS
1997
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
CROSS-TALK BETWEEN BACTERIAL PATHOGENS AND THEIR HOST CELLS
1996
CLONED POTASSIUM CHANNELS FROM EUKARYOTES AND PROKARYOTES
1997
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Structural Basis for a Ca 2+ -Sensing Function of the Metabotropic Glutamate Receptors
1998 Science
Common themes in microbial pathogenicity revisited
1997 Standout
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
1996 StandoutScience
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter
2003 StandoutNobel
Integrin Signaling
1999 StandoutScience
ASK1 Is Essential for JNK/SAPK Activation by TRAF2
1998
The MKK7 Gene Encodes a Group of c-Jun NH2-Terminal Kinase Kinases
1999
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants
2004
1997 StandoutNobel
Cloned avirulence genes from the tomato pathogen Pseudomonas syringae pv. tomato confer cultivar specificity on soybean
1989
Deficiency of the Stress Kinase P38α Results in Embryonic Lethality
2000
Expression of the Pseudomonas syringae avirulence protein AvrB in plant cells alleviates its dependence on the hypersensitive response and pathogenicity (Hrp) secretion system in eliciting genotype-specific hypersensitive cell death.
1996
Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases
1997 StandoutNobel
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants
1998 Standout
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Type III Secretion Machines: Bacterial Devices for Protein Delivery into Host Cells
1999 Science
Specification of Pore Properties by the Carboxyl Terminus of Inwardly Rectifying K + Channels
1994 Science
Allosteric activation of the CaR by l -amino acids
2000 StandoutNobel
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
The Cavity and Pore Helices in the KcsA K + Channel: Electrostatic Stabilization of Monovalent Cations
1999 StandoutScienceNobel
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase
1997
C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1.
1995
A quorum-sensing system in the free-living photosynthetic bacterium Rhodobacter sphaeroides
1997
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Signal Transduction through MAP Kinase Cascades
1998 Standout
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Activation of a heterologously expressed octopamine receptor coupled only to adenylyl cyclase produces all the features of presynaptic facilitation inAplysiasensory neurons
2000 StandoutNobel
Works of David Trollinger being referenced
Differential Expression and Activation of p38 Mitogen-Activated Protein Kinase α, β, γ, and δ in Inflammatory Cell Lineages
1999
Improved broad-host-range plasmids for DNA cloning in Gram-negative bacteria
1988
Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins
1995
Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages.
1999
Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cells
1995
Structural and Functional Aspects of the Multiplicity of Neu Differentiation Factors
1994
Atrial G protein-activated K+ channel: expression cloning and molecular properties.
1993
Molecular Cloning and Characterization of a Novel Protein Kinase with a Catalytic Domain Homologous to Mitogen-activated Protein Kinase Kinase Kinase
1996