Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions
2008 Science
Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase
2007 Science
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
2007
The Tandem BRCT Domain of 53BP1 Is Not Required for Its Repair Function
2006
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
2004 Nature
H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase
2007
Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks
2009
Necroptosis and its role in inflammation
2015 StandoutNature
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
The emerging role of nuclear architecture in DNA repair and genome maintenance
2009
Chromatin Modifications and Their Function
2007 Standout
The DNA damage response pathways: at the crossroad of protein modifications
2007
H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility
2003
Cell-cycle checkpoints and cancer
2004 StandoutNature
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
MDC1 Maintains Genomic Stability by Participating in the Amplification of ATM-Dependent DNA Damage Signals
2006
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
2008
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation
2004
Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention
2004
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
DNA damage checkpoints in mammals
2005
Pattern Recognition Receptors and Inflammation
2010 Standout
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
2008
Enhanced intra‐switch region recombination during immunoglobulin class switch recombination in 53BP1–/– B cells
2006
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
2011 Nature
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
The cellular response to DNA damage: A focus on MDC1 and its interacting proteins
2010
DNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis
2006
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
2012 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Intracellular Toll-like Receptors
2010 StandoutNobel
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Checking on DNA damage in S phase
2004
DNA Damage, Aging, and Cancer
2009 Standout
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
UV-induced Ataxia-telangiectasia-mutated and Rad3-related (ATR) Activation Requires Replication Stress
2004
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Expansion and evolution of cell death programmes
2008
Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α
2013
BLM is an early responder to DNA double-strand breaks
2006
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
2005
Positional stability of single double-strand breaks in mammalian cells
2007
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
2006
Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response
2013 StandoutNobel
Death receptor signal transducers: nodes of coordination in immune signaling networks
2009
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
2009 Nature
Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus Egg Extracts Requires Binding of ATRIP to ATR but Not the Stable DNA-binding or Coiled-coil Domains of ATRIP
2005
53BP1, an activator of ATM in response to DNA damage
2004
γH2AX and cancer
2008
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations
2006
The cellular response to general and programmed DNA double strand breaks
2004
Early events in the mammalian response to DNA double-strand breaks
2008
H2AX: the histone guardian of the genome
2004
Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break
2004
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
Colocalization of Sensors Is Sufficient to Activate the DNA Damage Checkpoint in the Absence of Damage
2008
Epigenetic Information in Chromatin: the Code of Entry for DNA Repair
2006
The Mre11 complex is required for ATM activation and the G2/M checkpoint
2003
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
2008
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
2006
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
2006
γH2Ax: Biomarker of Damage or Functional Participant in DNA Repair “All that Glitters Is not Gold!”
2011
TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
2008
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
TNF-α Induces Two Distinct Caspase-8 Activation Pathways
2008
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Roles of Replication Fork-interacting and Chk1-activating Domains from Claspin in a DNA Replication Checkpoint Response
2005
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
ATM Is Required for Efficient Recombination between Immunoglobulin Switch Regions
2004
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
2012
Following the Path of the Virus: The Exploitation of Host DNA Repair Mechanisms by Retroviruses
2006
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
2006
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
53BP1 Cooperates with p53 and Functions as a Haploinsufficient Tumor Suppressor in Mice
2005
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
H2AX Is Required for Recombination Between Immunoglobulin Switch Regions but Not for Intra-Switch Region Recombination or Somatic Hypermutation
2003
Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin
2008
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
The cellular response to DNA damage: A focus on MDC1 and its interacting proteins
2010
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Surviving the Breakup: The DNA Damage Checkpoint
2006
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Mechanism and Regulation of Class Switch Recombination
2008
Sporadic Epithelial Ovarian Cancer: Clinical Relevance of BRCA1 Inhibition in the DNA Damage and Repair Pathway
2008
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
High Mobility Group A2 Potentiates Genotoxic Stress in Part through the Modulation of Basal and DNA Damage–Dependent Phosphatidylinositol 3-Kinase–Related Protein Kinase Activation
2005
Non-homologous end-joining, a sticky affair
2007
Works of David Staudt being referenced
A dual role for ErbB2 signaling in cardiac trabeculation
2010
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
2003
Competitive Control of Independent Programs of Tumor Necrosis Factor Receptor-Induced Cell Death by TRADD and RIP1
2006