Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
2007 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
ATRIP Binding to Replication Protein A-Single-stranded DNA Promotes ATR–ATRIP Localization but Is Dispensable for Chk1 Phosphorylation
2005
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
2005
A Complex Consisting of Human Replication Factor C p40, p37, and p36 Subunits Is a DNA-dependent ATPase and an Intermediate in the Assembly of the Holoenzyme
1997
PCNA binding proteins
1999
Cell-cycle checkpoints and cancer
2004 StandoutNature
Chronic myeloid leukaemia as a model of disease evolution in human cancer
2007
Assembly of Functional Replication Factor C Expressed Using Recombinant Baculoviruses
1997
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
2006
DNA damage checkpoints in mammals
2005
ATR: an essential regulator of genome integrity
2008
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Deletion Analysis of the Large Subunit p140 in Human Replication Factor C Reveals Regions Required for Complex Formation and Replication Activities
1997
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Mechanism of the E. coli τ Processivity Switch during Lagging-Strand Synthesis
2003
Vaccinia Virus Uracil DNA Glycosylase Interacts with the A20 Protein to Form a Heterodimeric Processivity Factor for the Viral DNA Polymerase
2005
Checking on DNA damage in S phase
2004
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex
2000
Dephosphorylation of the C-terminal Tyrosyl Residue of the DNA Damage-related Histone H2A.X Is Mediated by the Protein Phosphatase Eyes Absent
2009
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin
2001
Impairment of Proliferating Cell Nuclear Antigen-dependent Apurinic/Apyrimidinic Site Repair on Linear DNA
1998
Telomerase-independent Regulation of ATR by Human Telomerase RNA
2006
Dynamics of β and Proliferating Cell Nuclear Antigen Sliding Clamps in Traversing DNA Secondary Structure
2000
The phosphorylated C‐terminal domain of Xenopus Cut5 directly mediates ATR‐dependent activation of Chk1
2006
Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response
2013 StandoutNobel
Biosynthesis of O-N-acetylgalactosamine glycans in the human cell nucleus
2018
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
2009 Nature
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus Egg Extracts Requires Binding of ATRIP to ATR but Not the Stable DNA-binding or Coiled-coil Domains of ATRIP
2005
Is the MCM2–7 complex the eukaryotic DNA replication fork helicase?
2001
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme
1999
ATR activation and replication fork restart are defective in FANCM‐deficient cells
2010
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
The cellular response to general and programmed DNA double strand breaks
2004
The structural determinants of checkpoint activation
2007
The Fanconi Anemia Protein FANCM Is Controlled by FANCD2 and the ATR/ATM Pathways
2009
Non-transcriptional control of DNA replication by c-Myc
2007 Nature
The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
2008
Crosstalk between histone modifications during the DNA damage response
2009
Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break
2004
The Hallmarks of Aging
2013 Standout
Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
2004
ATR Kinase Activation Mediated by MutSα and MutLα in Response to Cytotoxic O6-Methylguanine Adducts
2006
TopBP1 Activates the ATR-ATRIP Complex
2006
Multivalent engagement of chromatin modifications by linked binding modules
2007
DNA Ligase I and Proliferating Cell Nuclear Antigen Form a Functional Complex
2001
Polymerases and the Replisome: Machines within Machines
1998
Novel roles for A‐type lamins in telomere biology and the DNA damage response pathway
2009
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
Histone H2A.X Tyr142 phosphorylation: A novel sWItCH for apoptosis?
2009
Histone acetylation characterizes chromatin presetting by NF1 and Oct1 and enhances glucocorticoid receptor binding to the MMTV promoter
2009
Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
2009 StandoutNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
2012 StandoutNobel
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns
2010
CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
2005
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins
2007
β- N -acetylglucosamine (O-GlcNAc) is part of the histone code
2010
Rfc4 Interacts with Rpa1 and Is Required for Both DNA Replication and DNA Damage Checkpoints in Saccharomyces cerevisiae
2001
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Eukaryotic DNA Replication Fork
2017
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen
1999
Processive DNA helicase activity of the minichromosome maintenance proteins 4, 6, and 7 complex requires forked DNA structures
2001
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
2008
The Biology of Chromatin Remodeling Complexes
2009 Standout
In vitro reconstitution of human replication factor C from its five subunits.
1996
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Quality control in the initiation of eukaryotic DNA replication
2011
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation
2010 StandoutNobel
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
CBP-mediated acetylation of histone H3 lysine 27 antagonizesDrosophilaPolycomb silencing
2009
Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III
2001
Protein Phosphatase 5 Is Required for ATR-Mediated Checkpoint Activation
2005
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
DNA Replication in Eukaryotic Cells
2002 Standout
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells
1996
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
2011
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Works of David Shechter being referenced
Analysis of Histones in Xenopus laevis
2008
Regulation of DNA replication by ATR: signaling in response to DNA intermediates
2004
The Intrinsic DNA Helicase Activity of Methanobacterium thermoautotrophicum ΔH Minichromosome Maintenance Protein
2000
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity
2008 Nature
DNA Unwinding Is an MCM Complex-dependent and ATP Hydrolysis-dependent Process
2004
ATR and ATM regulate the timing of DNA replication origin firing
2004
An ATR- and Cdc7-Dependent DNA Damage Checkpoint that Inhibits Initiation of DNA Replication
2003
Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases
1996
Extraction, purification and analysis of histones
2007
ATM and ATR Check in on Origins: A Dynamic Model for Origin Selection and Activation
2004