Standout Papers

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis 2002 2026 2010 2018 1.5k
  1. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis (2002)
    David S Wald et al. BMJ

Citation Impact

Citing Papers

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008
2008 Standout
Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack
2014 Standout
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
2010 Standout
Primary Prevention of Ischemic Stroke
2006
Origins and evolution of the Western diet: health implications for the 21st century1,2
2005 Standout
Guidelines for the Primary Prevention of Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists.
2011
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Stroke rehabilitation
2011 Standout
Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial
2012
S-adenosyl-L-homocysteine hydrolase and methylation disorders: Yeast as a model system
2012
Effect of folic acid supplementation on the progression of carotid intima-media thickness: A meta-analysis of randomized controlled trials
2011
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
2004 Standout
The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis
2008
Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death
2006 Standout
Homocysteine and stroke: evidence on a causal link from mendelian randomisation
2005
Prothrombotic conditions, oral contraceptives, and the risk of ischemic stroke
2005
Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?
2007
Newborn Hearing Screening — A Silent Revolution
2006 Standout
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 Standout
Schizophrenia
2009 Standout
The Myth of the “Vulnerable Plaque”
2015
Cushing's syndrome
2015 Standout
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
2003 Standout
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Aspirin plus Clopidogrel as Secondary Prevention after Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis
2014 Standout
The changing landscape of atherosclerosis
2021 StandoutNature
The Homocysteine Hypothesis of Depression
2007
Fruit and vegetable consumption and stroke: meta-analysis of cohort studies
2006
Lowering Homocysteine in Patients With Ischemic Stroke to Prevent Recurrent Stroke, Myocardial Infarction, and Death
2004 Standout
Leisure Activities and the Risk of Dementia in the Elderly
2003 Standout
Guidelines for the Primary Prevention of Stroke
2010
Folate: A Functional Food Constituent
2009
Causal Relationship of Susceptibility Genes to Ischemic Stroke: Comparison to Ischemic Heart Disease and Biochemical Determinants
2010
Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction
2006 Standout
What can mendelian randomisation tell us about modifiable behavioural and environmental exposures?
2005
Efficacy of folic acid supplementation in stroke prevention: a meta-analysis
2007
Fluorescent and colorimetric probes for detection of thiols
2010 Standout
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
2017 Standout
Stroke
2008 Standout
Adiponectin Levels and Risk of Type 2 Diabetes
2009 Standout
Valvular Heart Disease and Pregnancy
2005
Effects of a Fixed-Dose Combination Strategy on Adherence and Risk Factors in Patients With or at High Risk of CVD
2013
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
2008 Standout
Secondary prevention with folic acid: effects on clinical outcomes
2003
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
2018 Standout
Major Depressive Disorder
2008 Standout
Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis
2015
Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
2009 Standout
Periodontal diseases
2005 Standout
A strategy to reduce cardiovascular disease by more than 80%
2003 Standout
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2007 Standout
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Cocaine and Other Stimulants
1988 Standout
Hyperhomocysteinemia in Patients with Cushing’s Syndrome
2004
Cushing's syndrome
2006 Standout
Effects of Intensive Blood Pressure Lowering on Cardiovascular and Renal Outcomes: A Systematic Review and Meta-Analysis
2012
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
2015 Standout
Thrombosis of the Cerebral Veins and Sinuses
2005 Standout
Cocaine Abuse Treatment
1984
Folate, Vitamin B 12 , and Risk of Ischemic and Hemorrhagic Stroke
2005
B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial
2010
Primary Prevention of Ischemic Stroke
2001
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
2005 Standout
C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus
2004
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol
2019 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Guidelines for the Primary Prevention of Stroke
2014 Standout
Folate Intake and Risk of Stroke Among Women
2004
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
2006 Standout
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
2006 Standout
Established and Emerging Plasma Biomarkers in the Prediction of First Atherothrombotic Events
2004
Dietary Folic Acid Promotes Survival of Foxp3+ Regulatory T Cells in the Colon
2012 StandoutNobel
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Homocysteine as a Risk Factor for Atherosclerosis: Is Its Conversion toS-Adenosyl-L-Homocysteine the Key to Deregulated Lipid Metabolism?
2011
Interventions to improve adherence to lipid-lowering medication
2016
Interventions for enhancing medication adherence
2014 Standout
Vitamin Intervention for Stroke Prevention Trial
2005
Hyperhomocysteinemia, Low Folate and Vitamin B 12 Concentrations, and Methylene Tetrahydrofolate Reductase Mutation in Cerebral Venous Thrombosis
2004
Primary Prevention of Ischemic Stroke
2001
Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials
2005
Joint British Societies’ consensus recommendations for the prevention of cardiovascular disease (JBS3)
2014
Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3
2003
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
2009 Standout
Heteroplasmy for the 1555A>G mutation in the mitochondrial 12S rRNA gene in six Spanish families with non-syndromic hearing loss
2003
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus
2010 Standout
Homocysteine and Risk of Recurrent Stroke
2003
Correlations between plasma homocysteine and folate concentrations and carotid atherosclerosis in high-risk individuals: baseline data from the Homocysteine and Atherosclerosis Reduction Trial (HART)
2008
Biomarkers of Cardiovascular Disease
2006
Effect of folic acid and B vitamins on risk of cardiovascular events and total mortality among women at high risk for cardiovascular disease: a randomized trial.
2008
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
1987 StandoutScience
Discrimination of homocysteine, cysteine and glutathione using an aggregation-induced-emission-active hemicyanine dye
2014
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout

Works of David S Wald being referenced

Folic acid, homocysteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidence
2006
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
2002 Standout
Adherence to Drugs That Prevent Cardiovascular Disease: Meta-analysis on 376,162 Patients
2012
Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials
2009
Implementation of a simple age‐based strategy in the prevention of cardiovascular disease: the Polypill approach
2011
Randomized Polypill Crossover Trial in People Aged 50 and Over
2012
Randomized Trial of Preventive Angioplasty in Myocardial Infarction
2013
Reconciling the Evidence on Serum Homocysteine and Ischaemic Heart Disease: A Meta-Analysis
2011
Randomised Trial of Text Messaging on Adherence to Cardiovascular Preventive Treatment (INTERACT Trial)
2014
Randomized Trial of Folic Acid Supplementation and Serum Homocysteine Levels
2001
The value of C-reactive protein in screening for future coronary heart disease events
2009
Haloperidol and lithium blocking of the mood response to intravenous methylphenidate
1978
Combining Carotid Intima-media Thickness with Carotid Plaque on Screening for Coronary Heart Disease
2009
Perceived contraindications to thrombolytic treatment in acute myocardial infarction. A survey at a teaching hospital.
1998
Rankless by CCL
2026