Citation Impact
Citing Papers
Hemizygous Disruption of Cdc25A Inhibits Cellular Transformation and Mammary Tumorigenesis in Mice
2007
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Cyclin D1 and Cdk4 Mediate Development of Neurologically Destructive Oligodendroglioma
2011
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
2007 StandoutScience
Regulation of Organogenesis by the Caenorhabditis elegans FoxA Protein PHA-4
2002 Science
Deregulated CDC25A Expression Promotes Mammary Tumorigenesis with Genomic Instability
2007
A Requirement for Cyclin-Dependent Kinase 6 in Thymocyte Development and Tumorigenesis
2009
Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers
2016
WGCNA: an R package for weighted correlation network analysis
2008 Standout
The CSL transcription factor LAG-1 directly represses hlh-6 expression in C. elegans
2008
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
2012
Expression of CDK4 or CDK2 in Mouse Oral Cavity Is Retained in Adult Pituitary with Distinct Effects on Tumorigenesis
2008
The DNA-damage response in human biology and disease
2009 StandoutNature
CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis
2014
Distinct requirements for C.elegans TAFIIs in early embryonic transcription
2001
Acromegaly
2006 Standout
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility
2008
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
2001
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression
2000
Establishment of a tissue-specific RNAi system in C. elegans
2007
Requirement for CDK4 kinase function in breast cancer
2006
Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia
2012
MYC on the Path to Cancer
2012 Standout
A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity
2008 StandoutNobel
A Gateway-Compatible Yeast One-Hybrid System
2004
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens
2012 StandoutNobel
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Transcriptional control and patterning of the pho-1 gene, an essential acid phosphatase expressed in the C. elegans intestine
2005
MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2
2014
Wound repair and regeneration
2008 StandoutNature
Imaging in the era of molecular oncology
2008 StandoutNature
Multiple regulatory elements with spatially and temporally distinct activities control the expression of the epithelial differentiation gene lin-26 in C. elegans
2003
The spatial dynamics of tissue-specific promoters during C. elegans development
2010
Cdk2 Knockout Mice Are Viable
2003
Cellular Senescence in Cancer and Aging
2007 Standout
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
2006
Cdk1 is sufficient to drive the mammalian cell cycle
2007 Nature
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport
2016 StandoutNobel
Proliferation of cancer cells despite CDK2 inhibition
2003
The Epigenomics of Cancer
2007 Standout
Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation
2010
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
The Drosophila Cyclin D-Cdk4 complex promotes cellular growth
2000
Development of mice expressing a single D-type cyclin
2002
p16INK4a induces an age-dependent decline in islet regenerative potential
2006 Nature
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
The human cumulus–oocyte complex gene-expression profile
2006
Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm
2002
Regulatory phases of early liver development: paradigms of organogenesis
2002
Can the cardiomyocyte cell cycle be reprogrammed?
2007
How stem cells age and why this makes us grow old
2007
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The mighty mouse: genetically engineered mouse models in cancer drug development
2006
Fiji: an open-source platform for biological-image analysis
2012 Standout
Cyclin D2 and cyclin D3 play opposite roles in mouse skin carcinogenesis
2006
Cyclin D as a therapeutic target in cancer
2011
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Anti‐aging activity of the Ink4/Arf locus
2009
TGFβ-related pathways
2000
Endocrine Regulation of Energy Metabolism by the Skeleton
2007 Standout
Automated analysis of embryonic gene expression with cellular resolution in C. elegans
2008
Unexpected Reduction of Skin Tumorigenesis on Expression of Cyclin-Dependent Kinase 6 in Mouse Epidermis
2011
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila
2003 Standout
Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
2016
Cyclin D-dependent kinases, INK4 inhibitors and cancer
2002
Living with or without cyclins and cyclin-dependent kinases
2004
Growth regulation by oncogenes — new insights from model organisms
2001
Stem Cells and Cancer
2004 Standout
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Mechanisms for pituitary tumorigenesis: the plastic pituitary
2003
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
The role of senescent cells in ageing
2014 StandoutNature
To cycle or not to cycle: a critical decision in cancer
2001
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
The Hallmarks of Aging
2013 Standout
Palbociclib and Letrozole in Advanced Breast Cancer
2016 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
The evolution of our thinking about microRNAs
2008 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
2009
Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells
2012
Cdk2-Null Mice Are Resistant to ErbB-2-Induced Mammary Tumorigenesis
2011
Cell cycle kinases as therapeutic targets for cancer
2009
Dynamic Chromatin Organization during Foregut Development Mediated by the Organ Selector Gene PHA-4/FoxA
2010
Drosophila Cyclin D/Cdk4 Requires Hif-1 Prolyl Hydroxylase to Drive Cell Growth
2004
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
2010 StandoutNature
Enhanced malignant tumorigenesis in Cdk4 transgenic mice
2003
Caenorhabditis elegans as a model for stem cell biology
2010
Norovirus Triggered Microbiota-driven Mucosal Inflammation in Interleukin 10-deficient Mice
2014
A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma
2010
Identification of CDK4 as a target of c-MYC
2000
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans
2005
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx
1999
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Cdk2 and Cdk4 Activities Are Dispensable for Tumorigenesis Caused by the Loss of p53
2009
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Systemic Iron Homeostasis
2013
CrebA regulates secretory activity in theDrosophilasalivary gland and epidermis
2005
DNA Double-Strand Breaks
2002 StandoutNobel
Targeting CDK4 and CDK6: From Discovery to Therapy
2015
Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration
2012
Wound-Healing Studies in Transgenic and Knockout Mice
2004
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Enteric bacteria promote human and mouse norovirus infection of B cells
2014 StandoutScience
Cdk2 Deficiency Decreases ras/CDK4-Dependent Malignant Progression, but Not myc-Induced Tumorigenesis
2007
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues
2004
Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth
2005
Works of David S. Moons being referenced
Transient or persistent norovirus infection does not alter the pathology of Salmonella typhimurium induced intestinal inflammation and fibrosis in mice
2011
The Cyclin-dependent Kinase Inhibitors p27Kip1 and p21Cip1 Cooperate to Restrict Proliferative Life Span in Differentiating Ovarian Cells
2003
cdk4 Deficiency Inhibits Skin Tumor Development but Does Not Affect Normal Keratinocyte Proliferation
2002
Cdk4 Is Indispensable for Postnatal Proliferation of the Anterior Pituitary
2004
The Hypoxia-Inducible Factor–C/EBPα Axis Controls Ethanol-Mediated Hepcidin Repression
2012
Intact Follicular Maturation and Defective Luteal Function in Mice Deficient for Cyclin- Dependent Kinase-4
2002
Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27Kip1 Activity
1999
Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4
2002
pha-4 is Ce-fkh-1, a fork head/HNF-3α,β,γ homolog that functions in organogenesis of the C. elegans pharynx
1998