Citation Impact
Citing Papers
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The effect of two different doses of aprotinin on hemostasis in cardiopulmonary bypass surgery: similar transfusion requirements and blood loss.
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The Antiinflammatory Effects of Aprotinin in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
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Epidemiology and causes of preterm birth
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Hypoxia-Inducible Factors in Physiology and Medicine
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Con: Tranexamic acid is not better than aprotinin in decreasing bleeding after cardiac surgery
1994
Re-graft patency and clinical efficacy of aprotinin in elective bypass surgery
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Aprotinin for coronary artery bypass grafting: Effect on postoperative renal function
1995
Tranexamic acid, given at the end of the operation, does not reduce postoperative blood loss in hip arthroplasty
2000
Effects of minimal-dose aprotinin on coronary artery bypass grafting
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Tranexamic Acid and Aprotinin Reduce Postoperative Bleeding and Transfusions During Primary Coronary Revascularization
1998
Management of Bleeding Complications in Redo Cardiac Operations
1998
Hemostatic efficacy of dipyridamole, tranexamic acid, and aprotinin in coronary bypass grafting
1995
Aprotinin counterbalances an increased risk of peri-operative haemorrhage in CABG patients pre-treated with Aspirin
1998
Tranexamic acid in aortic valve replacement
2001
Aprotinin versus desmopressin for patients undergoing operations with cardiopulmonary bypass
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The Dose-Response Relationship of Tranexamic Acid
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Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: a non-sponsored, double-blind, randomised, placebo-controlled trial☆
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Antifibrinolytic drugs and perioperative hemostasis
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Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) Trial: Rationale and design
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Operations on the thoracic aorta and hypothermic circulatory arrest: Is aprotinin safe?
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High-dose aprotinin in cardiac surgery: Three years' experience in 1,784 patients
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2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
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Effects of Minimal Dose Aprotinin on Blood Loss and Fibrinolytic System-Complement Activation in Coronary Artery Bypass Grafting Surgery
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Aprotinin in primary valve replacement and reconstruction: A multicenter, double-blind, placebo-controlled trial
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Drugs to Minimize Perioperative Blood Loss in Cardiac Surgery
1997
Aprotinin and tranexamic acid for high transfusion risk cardiac surgery
2000
Aprotinin Reduces Blood Loss in Patients Undergoing Elective Liver Resection
1997
Combined aprotinin and erythropoietin use for blood conservation: Results with Jehovah's Witnesses
1994
Tranexamic acid reduces blood loss and transfusion in reoperative cardiac surgery
1997
Topical use of aprotinin in open heart operations
1993
Recombinant aprotinin in coronary artery bypass graft operations
1995
Cytokine responses to cardiopulmonary bypass with membrane and bubble oxygenation
1992
Functional and chemical anatomy of the afferent vagal system
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A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension
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Tranexamic acid significantly reduces blood loss associated with coronary revascularization
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Aprotinin reduces blood loss and the need for transfusionin orthognathic surgery
2001
Effects of aprotinin on blood loss, heparin monitoring tests, and heparin doses in patients undergoing coronary artery bypass surgery
1995
High-Dose ϵ-Aminocaproic Acid Versus Aprotinin: Antifibrinolytic Efficacy in First-Time Coronary Operations
1998
Effect of low-dose aprotinin on coagulation and fibrinolysis in cardiopulmonary bypass
1993
Aprotinin efficacy on intraoperative bleeding and transfusion requirements in orthotopic liver transplantation
1994
Aprotinin and recombinant human erythropoietin reduce the need for homologous blood transfusion in cardiac surgery
1998
Aprotinin and Dipyridamole for the Safe Reduction of Postoperative Blood Loss
1998
Aprotinin Decreases Exposure to Allogeneic Blood During Primary Unilateral Total Hip Replacement*
2000
A Double-Blind, Placebo-Controlled Trial of Epsilon-Aminocaproic Acid for Reducing Blood Loss in Coronary Artery Bypass Grafting Surgery
2005
Insulin‐based regimens decrease mortality rates in critically ill patients: a systematic review
2006
Low-dose aprotinin in internal mammary artery bypass operations contributes to important blood saving
1992
Comparative Effects of Small and Large Aprotinin Doses on Bleeding During Orthotopic Liver Transplantation
1995
Aprotinin Decreases Blood Loss and Homologous Transfusions in Patients Undergoing Major Orthopedic Surgery
1998
Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: A systematic review and meta-analysis of randomized clinical trials
2004
Inflammatory response to cardiopulmonary bypass
1993 Standout
Aprotinin for Primary Coronary Artery Bypass Grafting: A Multicenter Trial of Three Dose Regimens
1996
Systemic sclerosis
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Improved haemodynamic stability with administration of aprotinin during orthotopic liver transplantation
1995
KEY ISSUES IN ADVANCED BLEEDING CARE IN TRAUMA
2006
Hemostatic Drugs
1998
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Effect of tranexamic acid on blood loss reduction after cardiopulmonary bypass
2001
Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
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Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Reduction of bleeding after heart operations through the prophylactic use of epsilon-aminocaproic acid
1996
A possible association between aprotinin and improved survival after radical surgery for mesothelioma
2009
Tranexamic Acid Reduces Blood Loss, Transfusion Requirements, and Coagulation Factor Use in Primary Orthotopic Liver Transplantation
1996
Oxygen Free Radicals and Brain Dysfunction
1991
The ongoing variability in blood transfusion practices in cardiac surgery
2008
Kidney-specific proteins in patients receiving aprotinin at high- and low-dose regimens during coronary artery bypass graft with cardiopulmonary bypass
2005
Reduction in Costs, Blood Products, and Operating Time in Patients Undergoing Open Heart Surgery
1997
Effects of high-dose aprotinin on renal function in aortocoronary bypass grafting
1995
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Randomized, Placebo-Controlled, Double-Blind Study of an Ultra-Low-Dose Aprotinin Regimen in Reoperative and/or Complex Cardiac Operations
1997
Heparin-Level-Based Anticoagulation Management During Cardiopulmonary Bypass: A Pilot Investigation on the Effects of a Half-Dose Aprotinin Protocol on Postoperative Blood Loss and Hemostatic Activation and Inflammatory Response
2004
Activation of polymorphonuclear leukocytes in oleic acid-induced lung injury
1998
Aprotinin reduces intraoperative and postoperative blood loss in membrane oxygenator cardiopulmonary bypass
1991
Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary operations
2001
The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis
2008
High-dose aprotinin modulates the balance between proinflammatory and anti-inflammatory responses during coronary artery bypass graft surgery
2000
Phenotypic distinctions between neural crest and placodal derived vagal C-fibres in mouse lungs
2010
Cytokine release and neutrophil activation are not prevented by heparin-coated circuits and aprotinin administration
2000
Influence of High-dose Aprotinin on Anticoagulation, Heparin Requirement, and Celite- and Kaolin-Activated Clotting Time in Heparin-pretreated Patients Undergoing Open-Heart Surgery
1995
The Efficacy of Antifibrinolytics in the Reduction of Blood Loss During Complex Adult Reconstructive Spine Surgery
2001
Aprotinin Decreases Blood Loss in Patients Undergoing Revision or Bilateral Total Hip Arthroplasty
1995
Tranexamic Acid and Aprotinin in Primary Cardiac Operations: An Analysis of 220 Cardiac Surgical Patients Treated with Tranexamic Acid or Aprotinin
2008
Aprotinin (Trasylol) does not reduce bleeding in primary total hip arthroplasty
2000
Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage
2005 Standout
Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints
1999
Systemic inflammatory responses to cardiopulmonary bypass: A pilot study of the effects of pentoxifylline
1993
Die Wirkung von Aprotinin
1997
Anesthesiology
1997 Standout
Platelet function during cardiac surgery and cardiopulmonary bypass with low-dose aprotinin
1999
Platelet protection by low-dose aprotinin in cardiopulmonary bypass: Electron microscopic study
1993
Effects of aprotinin on hemorrhagic complications in ARDS patients during prolonged extracorporeal CO2 removal
1992
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Low-dose and high-dose aprotinin improve hemostasis in coronary operations
1996
Decreased postoperative drainage with addition of ϵ-aminocaproic acid before cardiopulmonary bypass
1994
Leukocyte integrin expression in patients undergoing cardiopulmonary bypass
2000
The Impact of Aprotinin on Coronary Artery Bypass Graft Patency
1994
Postoperative intravenous iron used alone or in combination with low-dose erythropoietin is not effective for correction of anemia after cardiac surgery
2004
Safety of Low-Dose Aprotinin in Coronary Artery Bypass Graft Surgery
2008
Tranexamic acid compared with high-dose aprotinin in primary elective heart operations: Effects on perioperative bleeding and allogeneic transfusions
2000
Remifentanil
1996
Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury
1996
A pump-prime aprotinin dose in cardiac surgery: Appraisal of its effects on the hemostatic system
1997
No impact of a leucocyte depleting arterial line filter on patient recovery after cardiopulmonary bypass
2001
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
2009 Standout
Half-dose aprotinin preserves hemostatic function in patients undergoing bypass operations
1995
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
2011 Standout
Factor XIIIA and clot strength after cardiopulmonary bypass
2001
Economic evaluation of high-dose and low-dose aprotinin therapy during cardiopulmonary bypass
1999
Suppressed fibrinolysis after administration of low-dose aprotinin: reduced level of plasmin-alpha-plasmin inhibitor complexes and postoperative blood loss
1995
Tranexamic Acid Reduces Bleeding After Cardiopulmonary Bypass When Compared to Epsilon Aminocaproic Acid and Placebo
1997
Plasma Tranexamic Acid Concentrations During Cardiopulmonary Bypass
2001
Platelet transfusions are not associated with increased morbidity or mortality in cardiac surgery
2006
Amelioration of the bleeding tendency of preoperative aspirin after aortocoronary bypass grafting
2000
Aprotinin preserves hemostasis in aspirin-treated patients undergoing cardiopulmonary bypass
1994
Aprotinin Versus Placebo in Major Orthopedic Surgery: A Randomized, Double-Blinded, Dose-Ranging Study
2002
Intrauterine Infection and Preterm Delivery
2000 Standout
The Efficacy of Aprotinin in Arterial Switch Operations in Infants
2008
Efficacy and Safety of Recombinant Activated Factor VII for Acute Intracerebral Hemorrhage
2008 Standout
Aprotinin reduces red blood cell transfusion in orthotopic liver transplantation: A prospective, randomized, double-blind study
2001
Effect of Reduced Aprotinin Dosage on Blood Loss and Use of Blood Products in Patients Undergoing Cardiopulmonary Bypass
1993
Hypoxic gene expression and metastasis
2004
The Perioperative Management of Antithrombotic Therapy
2008
Hospital variation in transfusion and infection after cardiac surgery: a cohort study
2009
Adverse effects of methods for minimizing perioperative allogeneic transfusion: A critical review of the literature
1998
Lower cardiac troponin T levels in patients undergoing cardiopulmonary bypass and receiving high-dose aprotinin therapy indicate reduction of perioperative myocardial damage
1995
A propensity score case‐control comparison of aprotinin and tranexamic acid in high‐transfusion‐risk cardiac surgery
2006
Atherosclerosis — An Inflammatory Disease
1999 Standout
Natural and synthetic antifibrinolytics in adult cardiac surgery: efficacy, effectiveness and efficiency
1994
Postoperative aprotinin: Effect on blood loss and transfusion requirements in cardiac operations
1996
Colorimetric assay of heparin in plasma based on the inhibition of oxidase-like activity of citrate-capped platinum nanoparticles
2016
Race, Perinatal Outcome, and Amniotic Infection
1996
A comparison of the effects of tranexamic acid and low-dose aprotinin on blood loss and homologous blood usage in patients undergoing cardiac surgery
1995
Effect of ambient particulate matter exposure on hemostasis
2007
Warfarin pretreatment does not lead to increased bleeding tendency during cardiac surgery
1995
The Effect of Epsilon-Aminocaproic Acid and Aprotinin on Fibrinolysis and Blood Loss in Patients Undergoing Primary, Isolated Coronary Artery Bypass Surgery: A Randomized, Double-Blind, Placebo-Controlled, Noninferiority Trial
2009
The efficacy of single-dose aprotinin 2 million KIU in reducing blood loss and its impact on the incidence of deep venous thrombosis in patients undergoing total hip replacement surgery
1996
The Pathophysiology and Treatment of Sepsis
2003 Standout
Low-dose postoperative aprotinin reduces mediastinal drainage and blood product use in patients undergoing primary coronary artery bypass grafting who are taking aspirin: A prospective, randomized, double-blind, placebo-controlled trial
2001
Aprotinin, Blood Loss, and Renal Dysfunction in Deep Hypothermic Circulatory Arrest
2001
Reduction of Blood Loss and Transfusion Requirements After Coronary Artery Bypass Grafting:.
1999
Comparison of epsilon aminocaproic acid and low-dose aprotinin in cardiopulmonary bypass: efficiency, safety and cost
2001
Pro: Tranexamic acid is better than aprotinin in decreasing bleeding after cardiac surgery
1994
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
1999
Influence of High- and Low-Dose Aprotinin on Activation of Hemostasis in Open Heart Operations
1998
Tranexamic Acid Reduces Transfusions and Mediastinal Drainage in Repeat Cardiac Surgery
1996
Differential Effects of Epsilon-aminocaproic Acid and Aprotinin on Matrix Metalloproteinase Release in Patients Following Cardiopulmonary Bypass
2008
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Analyses of coronary graft patency after aprotinin use: Results from the international multicenter aprotinin graft patency experience (IMAGE) trial
1998
The Risks of Aprotinin and Tranexamic Acid in Cardiac Surgery: A One-Year Follow-Up of 1188 Consecutive Patients
2008
Postoperative use of aprotinin in cardiac operations: An alternative to its prophylactic use
1996
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Low-dose aprotinin infusion is not clinically useful to reduce bleeding and transfusion of homologous blood products in high-risk cardiac surgical patients
1993
Cost-Benefit and Efficacy of Aprotinin Compared with ε-Aminocaproic Acid in Patients Having Repeated Cardiac Operations
1997
Transfusion Medicine
2001
Severe Neurologic Deficit after Nitrous Oxide Anesthesia
1995
Tranexamic acid reduces bleeding and the need for blood transfusion in primary myocardial revascularization
2002
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration
2009 Standout
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
The inflammatory reflex
2002 StandoutNature
Increased epithelial permeability in pulmonary fibrosis in relation to disease progression
2010
Aprotinin reduces cardiopulmonary bypass‐induced blood loss and inhibits fibrinolysis without influencing platelets
1993
Aprotinin Does Not Diminish Blood Loss in Elective Operations for Infrarenal Abdominal Aneurysms: A Randomized Double-Blind Controlled Trial
2006
Overview of the innervation of the lung
2002
A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Surgery
2008
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
cardiopulmonary bypass in patients?
2003
Autologous platelet sequestration in patients undergoing coronary artery bypass grafting
1996
Prevention and Treatment of Major Blood Loss
2007
Fibrinolysis-adjusted perioperative low-dose aprotinin reduces blood loss in bypass operations
1998
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
Reduced blood loss by aprotinin in thoracic surgical operations associated with high risk of bleeding. A placebo-controlled, randomized phase IV study
2001
A comparison before and after aprotinin was suspended in cardiac surgery: Different results in the real world from a single cardiac center in China
2009
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
The efficacy and safety of aprotinin for hemostasis during intracranial surgery
2003
Reduction in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin versus autologous fresh whole blood transfusion
1992
High-Dose Aprotinin: Hemostatic Effects in Open Heart Operations
1989
Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial
2008
Substance P expression in TRPV1 and trkA-positive dorsal root ganglion neurons innervating the mouse lung
2004
Efficacy of Aprotinin in Different Doses and Autologous Blood Transfusions in Cardiac Surgery
1994
Combination of Acute Preoperative Plateletpheresis, Cell Salvage, and Aprotinin Minimizes Blood Loss and Requirement During Cardiac Surgery
2005
Standardized Bleeding Definitions for Cardiovascular Clinical Trials
2011 Standout
Effect of intraoperative aprotinin administration on postoperative bleeding in patients undergoing cardiopulmonary bypass operation
1991
Oxidants, antioxidants, and the degenerative diseases of aging.
1993 Standout
Tranexamic acid (Cyklokapron) is not necessary to reduce blood loss after coronary artery bypass operations
1993
Toxic Potential of Materials at the Nanolevel
2006 StandoutScience
Effect of cardiopulmonary bypass on systemic release of neutrophil elastase and tumor necrosis factor
1993
Life with Oxygen
2007 StandoutScienceNobel
Hemostatic effects of aprotinin, tranexamic acid and ϵ-aminocaproic acid in primary cardiac surgery
1999
Acrolein Depletes the Neuropeptides CGRP and Substance P in Sensory Nerves in Rat Respiratory Tract
1990
Prospective randomized placebo-controlled trial of aprotinin for elective aortic reconstruction
1997
2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines
2011 Standout
Tranexamic Acid Reduces Transfusions and Mediastinal Drainage in Repeat Cardiac Surgery
1996
Aprotinin significantly decreases bleeding and transfusion requirements in patients receiving aspirin and undergoing cardiac operations
1994
Mechanisms of macromolecule absorption by the lungs
1996
Efficacy and safety of aprotinin in aortocoronary bypass and valve replacement operations: a placebo-controlled randomized double-blind study
1996
AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update
2006 Standout
Aprotinin Decreases Postoperative Bleeding and Number of Transfusions in Patients on Clopidogrel Undergoing Coronary Artery Bypass Graft Surgery
2005
“Low-Dose” Aprotinin Modifies Hemostasis but Not Proinflammatory Cytokine Release
1997
Acrolein depletes the neuropeptides CGRP and substance P in sensory nerves in rat respiratory tract.
1990
Comparative outcome of heart-lung and lung transplantation for pulmonary hypertension
1993
AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update
2006
Prospective randomized placebo-controlled trial of aprotinin for elective aortic reconstruction
1997
Review article : Blood compatibility of cardiopulmonary bypass circuits
1987
Anticoagulation Monitoring during Cardiac Surgery
1999
Comparaison des effets de l’aprotinine et de l’acide tranexamique sur le saignement en chirurgie cardiaque
1995
FIBRINOLYTIC INHIBITION WITH TRANEXAMIC ACID REDUCES BLOOD LOSS AND BLOOD TRANSFUSION AFTER KNEE ARTHROPLASTY
1996
Effect of aprotinin (Trasylol) on aorta-coronary bypass graft patency
1993
Drugs to Minimize Perioperative Blood Loss in Cardiac Surgery
1997
Defining the Role of Aprotinin in Heart Transplantation
1996
Aprotinin Reduces Blood Loss in Patients Undergoing Elective Liver Resection
1997
Aprotinin therapy for reoperative myocardial revascularization: A placebo-controlled study
1992
Effect of strenuous exercise on platelet activation state and reactivity.
1993
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Leukocyte depletion ameliorates free radical-mediated lung injury after cardiopulmonary bypass
1990
Insulin Therapy for Critically Ill Hospitalized Patients
2004
Effect of Nitrous Oxide on Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures
1998
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
2011 Standout
Low factor XIIIA levels are associated with increased blood loss after coronary artery bypass grafting
1994
Aprotinin for coronary bypass operations: efficacy, safety, and influence on early saphenous vein graft patency. A multicenter, randomized, double-blind, placebo-controlled study.
1994
Is ε-Aminocaproic Acid as Effective as Aprotinin in Reducing Bleeding With Cardiac Surgery?
1999
Effects of hemofiltration on serum a protinin levels in patients undergoing cardiopulmonary bypass
2000
Comparison of two doses of aprotinin in patients receiving aspirin before coronary bypass surgery
2000
Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage.
1992
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Making Antibodies by Phage Display Technology
1994 StandoutNobel
High-dose Aprotinin in Cardiac Surgery—A Prospective, Randomized Study
1994
Diagnosis of MI after CABG with high-sensitivity troponin T and new ECG or echocardiogram changes: relationship with mortality and validation of the Universal Definition of MI
2013
Exposure to Ultrafine Particles from Ambient Air and Oxidative Stress–Induced DNA Damage
2007
Risk Factors for Acute Postoperative Renal Failure in Thoracic or Thoracoabdominal Aortic Surgery
1997
Randomized placebo-controlled double-blind study of three aprotinin regimens in primary cardiac surgery
1994
Aprotinin protects platelets against the initial effect of cardiopulmonary bypass
1990
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Effect of prophylactic epsilon-aminocaproic acid on blood loss and transfusion requirements in patients undergoing first-time coronary artery bypass grafting
1994
Blood activation during neonatal extracorporeal life support
1993
Randomized study of aprotinin and DDAVP to reduce postoperative bleeding after cardiopulmonary bypass surgery.
1994
Protease Inhibitors: Current Status and Future Prospects
2000
Coronary Plaque Disruption
1995 Standout
Particulate Matter Air Pollution and Cardiovascular Disease
2010 Standout
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
Ultra-Early Hemostatic Therapy for Intracerebral Hemorrhage
2003
A Multicenter, Double-Blind, Placebo-Controlled Trial of Aprotinin for Reducing Blood Loss and the Requirement for Donor-Blood Transfusion in Patients Undergoing Repeat Coronary Artery Bypass Grafting
1995
Aprotinin does not decrease early graft patency after coronary artery bypass grafting despite reducing postoperative bleeding and use of donated blood
1994
Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation
2006
Renal dysfunction in cardiac surgery: identifying potential risk factors
2009
Effect of Aprotinin on Plasma Fibronectin Levels During Cardiopulmonary Bypass
1997
Neutrophil degranulation and increased pulmonary capillary permeability following oesophagectomy: A model of early lung injury in man
1988
Intraoperative antifibrinolysis and blood-saving techniques in cardiac surgery. Prospective trial of 3 antifibrinolytic drugs.
1995
Avoidance of Allogeneic Blood Transfusions by Treatment With Epoetin Beta (Recombinant Human Erythropoietin) in Patients Undergoing Open-Heart Surgery
1997
Comparison of the effects of aprotinin and tranexamic acid on blood loss and related variables after cardiopulmonary bypass
1994
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
2010 Standout
Effects of hemofiltration on serum aprotinin levels in patients undergoing cardiopulmonary bypass
2000
Assessment of ability of murine and human anti-lipid A monoclonal antibodies to bind and neutralize lipopolysaccharide.
1993
2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction
2011
Use of desmopressin and erythropoietin in an anaemic Jehovah’s Witness patient with severely impaired coagulation capacity undergoing stentless aortic valve replacement
2001
Part 14: Pediatric Advanced Life Support
2010 Standout
Colloids versus crystalloids for fluid resuscitation in critically ill patients
2013
Aprotinin Has no Effect on Platelet Activation and Adhesion during Cardiopulmonary Bypass
1996
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Inhibition by dexamethasone of the reperfusion phenomena in cardiopulmonary bypass
1991
Tranexamic Acid and Aprotinin Reduce Postoperative Bleeding and Transfusions During Primary Coronary Revascularization
1998
Preoperative Platelet Dysfunction Increases the Benefit of Aprotinin in Cardiopulmonary Bypass
1997
Weekend versus Weekday Admission and Mortality from Myocardial Infarction
2007 Standout
Hemostasis in Patients Undergoing Extracorporeal Circulation: The Effect of Aprotinin (Trasylol)
1991
Effect of prophylactic epsilon-aminocaproic acid on blood loss and transfusion requirements in patients undergoing first-time coronary artery bypass grafting. A randomized, prospective, double-blind study.
1994
Hemostatic effects of tranexamic acid and desmopressin during cardiac surgery.
1991
2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction
2013
Aprotinin and transfusion requirements in orthotopic liver transplantation: a multicentre randomised double-blind study
2000
Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline
2007
Works of David Royston being referenced
Blood Use in Cardiac Surgery
1991
EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION AFTER REPEAT OPEN-HEART SURGERY
1987
Aprotinin Versus Lysine Analogues: The Debate Continues
1998
Cardiopulmonary effects of 7.2% saline solution compared with gelatin infusion in the early postoperative period after coronary artery bypass grafting
1998
The Society of Thoracic Surgeons Practice Guideline Series: Aspirin and Other Antiplatelet Agents During Operative Coronary Revascularization (Executive Summary)*
2005
Coronary revascularization: A procedure in transition from on-pump to off-pump? The role of glucose-insulin-potassium revisited in a randomized, placebo-controlled study
2002
Safety aspects of aprotinin therapy in cardiac surgery patients
2006
PERIOPERATIVE BLEEDING Drugs for surgical blood loss
1993
Retrograde tracing shows that CGRP-immunoreactive nerves of rat trachea and lung originate from vagal and dorsal root ganglia
1987
Platelet transfusions during coronary artery bypass graft surgery are associated with serious adverse outcomes
2004
Reduced blood lass following open heart surgery with aprotinin (trasylol) is associated with an increase in intraoperative activated clotting time (ACT)
1989
Reduced haemostatic factor transfusion using heparinase-modified thrombelastography during cardiopulmonary bypass
2001
Aprotinin therapy in cardiac operations: A report on use in 41 cardiac centers in the United Kingdom
1993
Pharmacological approaches to reducing allogeneic blood exposure
2003
The Comparison and Validity of Troponin I Assay Systems in Diagnosing Myocardial Ischemic Injury After Surgical Coronary Revascularization
2005
Serine Protease Inhibition Prevents Both Cellular and Humoral Responses to Cardiopulmonary Bypass
1996
Full-Dose Aprotinin Use in Coronary Artery Bypass Graft Surgery: An Analysis of Perioperative Pharmacotherapy and Patient Outcomes
2006
Is Perioperative Plasma Aprotinin Concentration More Predictable and Constant After a Weight-Related Dose Regimen?
2001
Preventing the inflammatory response to open-heart surgery: The role of aprotinin and other protease inhibitors
1996
Aprotinin; friend or foe? A review of recent medical literature
2006
Thrombin generation and its inhibition: a review of the scientific basis and mechanism of action of anticoagulant therapies
2002
Increased Pulmonary Transvascular Protein Flux after Canine Cardiopulmonary Bypass
1986
Coagulation in cardiac surgery.
1996
Aprotinin in open-heart surgery: background and results in patients having aortocoronary bypass grafts
1990
Aprotinin and perioperative complications in cardiac surgery
2007
The Effect of Nicotine on Pulmonary Epithelial Permeability in Man
1984
SERUM METHIONINE AND HEPATIC ENZYME ACTIVITY IN ANAESTHETISTS EXPOSED TO NITROUS OXIDE
1982
Remifentanil in cardiac surgery.
1995
The serine antiprotease aprotinin (Trasyloltm)
1990
THE PHYSIOLOGY OF LEAKY LUNGS
1982
Aprotinin in aspirin-pretreated patients
1990
Blood-sparing Drugs
1995
Use of Intra-Operative High Dose Aprotinin May Be Associated with Improved Longer Term Outcome Following Esophagectomy for Cancer
2002
Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol)
1989
The Effect of Surgery with Cardiopulmonary Bypass on Alveolar-Capillary Barrier Function in Human Beings
1985
Comparison of lung vascular and epithelial permeability indices in the adult respiratory distress syndrome.
1986
Increased production of peroxidation products associated with cardiac operations
1986
The effect of human antiendotoxin monoclonal antibodies on endotoxin-induced lung injury in the rat.
1987
Positive end-expiratory pressure increases pulmonary clearance of inhaled 99mTc-DTPA in nonsmokers but not in healthy smokers.
1987
High-dose aprotinin therapy: A review of the first five years' experience
1992
Effect of raised thoracic pressure and volume on 99mTc-DTPA clearance in humans
1986
Pulmonary epithelial permeability is immediately increased after embolisation with oleic acid but not with neutral fat.
1982
Blood-sparing Drugs
1994
Aprotinin and perioperative complications in cardiac surgery.
2007
Rate of Inactivation of Human and Rodent Hepatic Methionine Synthase by Nitrous Oxide
1988
Free radicals
1988
Evaluating the role of serine protease inhibition in the management of tumor micrometastases.
2003
Amniotic fluid infection with intact membranes in relation to stillborns.
1985