Citation Impact
Citing Papers
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Phenotypic plasticity and the epigenetics of human disease
2007 Nature
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
1994 Standout
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Molecular Bases for Circadian Clocks
1999 Standout
Epigenetics: A Landscape Takes Shape
2007 Standout
Plant cell wall architecture
1989
Epigenetic therapy of cancer: past, present and future
2006
Degradation Signal Masking by Heterodimerization of MATα2 and MATa1 Blocks Their Mutual Destruction by the Ubiquitin-Proteasome Pathway
1998
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
1993 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Tumor Cell Metabolism: Cancer's Achilles' Heel
2008 Standout
Stem cells find their niche
2001 StandoutNature
Heat shock protein 90: The cancer chaperone
2007
HSP90 and the chaperoning of cancer
2005 Standout
The Epigenomics of Cancer
2007 Standout
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
2006
Epigenetics in Cancer
2008 Standout
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
2002 StandoutNature
Isolation, Characterization, and Partial Purification of a Novel Ubiquitin-Protein Ligase, E3
1996 StandoutNobel
Ectopic Expression of Nonliganded Retinoic Acid Receptor β Abrogates AP-1 Activity by Selective Degradation of c-Jun in Cervical Carcinoma Cells
2004 StandoutNobel
Molecular characterization of the Notch homologue from the Australian sheep blowfly, Lucilia cuprina
1998
Metazoan MicroRNAs
2018 Standout
The N-end rule
1992
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
2008 Nature
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Ubiquitin-dependent Degradation of Certain Protein Substrates in Vitro Requires the Molecular Chaperone Hsc70
1997 StandoutNobel
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
2010
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
1996 StandoutNobel
Homeodomain-DNA recognition
1994 StandoutNobel
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
2009 Standout
MicroRNAs in the Drosophila bithorax complex
2008
Susceptibility of Human Head and Neck Cancer Cells to Combined Inhibition of Glutathione and Thioredoxin Metabolism
2012
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
1994 Standout
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
PDF and cAMP enhance PER stability in Drosophila clock neurons
2014 StandoutNobel
The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other segmentation gap genes
1992
Clues from cell metabolism
2010 StandoutNatureNobel
In vivo analysis of the helix-turn-helix motif of the fushi tarazu homeo domain of Drosophila melanogaster.
1992
Sequence analysis of the cis-regulatory regions of the bithorax complex of Drosophila.
1995 StandoutNobel
Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain
1994
Ubiquitin–mediated proteolysis and male sterility
1996 StandoutNobel
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo.
1991
Regulation by proteolysis: energy-dependent proteases and their targets
1992
Altered Hsp90 function in cancer: A unique therapeutic opportunity
2004
Molecular coevolution within a Drosophila clock gene
1998 StandoutNobel
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins.
1994 StandoutNobel
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
1994 StandoutNobel
odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos.
1994
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-“N-end rule” protein substrates
1994 StandoutNobel
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
bag-of-marbles and benign gonial cell neoplasm act in the germline to restrict proliferation during Drosophila spermatogenesis
1997
Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2
1994 StandoutNobel
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Circadian Cycling of a PERIOD-β-galactosidase Fusion Protein in Drosophila: Evidence for Cyclical Degradation
1997 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
To shape a cell: an inquiry into the causes of morphogenesis of microorganisms
1990
Works of David Mattson being referenced
Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress
2011
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach
2004
2-Deoxy-d -Glucose Combined with Cisplatin Enhances Cytotoxicity via Metabolic Oxidative Stress in Human Head and Neck Cancer Cells
2007
Nucleated assembly of Chlamydomonas and Volvox cell walls.
1987
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
2003
Mutations affecting the stability of the fushi tarazu protein of Drosophila.
1990