Citation Impact
Citing Papers
Nuclear Activity of MLA Immune Receptors Links Isolate-Specific and Basal Disease-Resistance Responses
2006 Science
Cleavage of Arabidopsis PBS1 by a Bacterial Type III Effector
2003 Science
The Melampsora lini AvrL567 Avirulence Genes Are Expressed in Haustoria and Their Products Are Recognized inside Plant Cells
2004
A Genome-Wide Survey of R Gene Polymorphisms in Arabidopsis
2006
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
2009 StandoutScience
Regulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors
2009 StandoutScience
Cladosporium Avr2 Inhibits Tomato Rcr3 Protease Required for Cf-2 -Dependent Disease Resistance
2005 Science
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response
2008 Science
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation
2005
Activation of a Phytopathogenic Bacterial Effector Protein by a Eukaryotic Cyclophilin
2005 Science
A Bacterial Virulence Protein Suppresses Host Innate Immunity to Cause Plant Disease
2006 Science
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
2009 StandoutScience
A Pseudomonas syringae type III effector suppresses cell wall-based extracellular defense in susceptible Arabidopsis plants
2003
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
2013 StandoutScience
Direct protein interaction underlies gene-for-gene specificity and coevolution of the flax resistance genes and flax rust avirulence genes
2006
Elicitor-Mediated Oligomerization of the Tobacco N Disease Resistance Protein
2005
Convergent Evolution of Disease Resistance Gene Specificity in Two Flowering Plant Families[W]
2004
A Patch of Surface-Exposed Residues Mediates Negative Regulation of Immune Signaling by Tomato Pto Kinase[W]
2004
Expanded functions for a family of plant intracellular immune receptors beyond specific recognition of pathogen effectors
2011
High-throughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance
2012
The N-terminal Domain of Drosophila Gram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors
2009 StandoutNobel
RD19, anArabidopsisCysteine Protease Required for RRS1-R–Mediated Resistance, Is Relocalized to the Nucleus by theRalstonia solanacearumPopP2 Effector
2008
A “Whirly” Transcription Factor Is Required for Salicylic Acid-Dependent Disease Resistance in Arabidopsis
2004
Tobacco Transgenic for the Flax Rust Resistance Gene L Expresses Allele-Specific Activation of Defense Responses
2004
Deletions in the Repertoire of Pseudomonas syringae pv. tomato DC3000 Type III Secretion Effector Genes Reveal Functional Overlap among Effectors
2009
Abiotic Stress Signaling and Responses in Plants
2016 Standout
Activation of a COI1‐dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine
2004
Type III effector proteins: doppelgangers of bacterial virulence
2006
The role and regulation of programmed cell death in plant-pathogen interactions
2004
Pathogen derived elicitors: searching for receptors in plants
2002
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
Two different CC‐NBS‐LRR genes are required for Lr10‐mediated leaf rust resistance in tetraploid and hexaploid wheat
2009
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Plant Defense
2003
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
Regulation of Tomato Prf by Pto-like Protein Kinases
2009
Pseudomonas syringae effector AvrPtoB suppresses basal defence in Arabidopsis
2006
RNA silencing is required for Arabidopsis defence against Verticillium wilt disease
2008
Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNA
2006
Inflammasomes: guardians of cytosolic sanctity
2008
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Genetic and molecular evidence that the Pseudomonas syringae type III effector protein AvrRpt2 is a cysteine protease
2003
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Pseudomonas syringae Effector AvrPto Blocks Innate Immunity by Targeting Receptor Kinases
2008
Mechanisms of plant resistance to viruses
2005
The type III needle and the damage done
2005
Plant Pattern-Recognition Receptor FLS2 Is Directed for Degradation by the Bacterial Ubiquitin Ligase AvrPtoB
2008
Network Properties of Robust Immunity in Plants
2009
Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System
2009
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
2006
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Plant recognition of microbial patterns
2003
Pathogen virulence factors as molecular probes of basic plant cellular functions
2007
RRS1 and RPS4 provide a dual Resistance‐gene system against fungal and bacterial pathogens
2009
Cotton S-adenosylmethionine decarboxylase-mediated spermine biosynthesis is required for salicylic acid- and leucine-correlated signaling in the defense response to Verticillium dahliae
2016
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant?microbe interactions
2007
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Molecular diversity at the plant–pathogen interface
2007
NLRs join TLRs as innate sensors of pathogens
2005
A Novel Role for the TIR Domain in Association with Pathogen-Derived Elicitors
2007
Complex formation, promiscuity and multi-functionality: protein interactions in disease-resistance pathways
2003
Plant pathogenic bacterial type III effectors subdue host responses
2008
A new vision of immunity: homeostasis of the superorganism
2010
Suppression of host defense in compatible plant–Pseudomonas syringae interactions
2005
Fitness costs of R-gene-mediated resistance in Arabidopsis thaliana
2003 Nature
Receptor quality control in the endoplasmic reticulum for plant innate immunity
2009
Perception of the Bacterial PAMP EF-Tu by the Receptor EFR Restricts Agrobacterium-Mediated Transformation
2006
Plant immunity: towards an integrated view of plant–pathogen interactions
2010 Standout
A bacterial E3 ubiquitin ligase targets a host protein kinase to disrupt plant immunity
2007 Nature
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
R gene expression induced by a type-III effector triggers disease resistance in rice
2005 Nature
Prf immune complexes of tomato are oligomeric and contain multiple Pto‐like kinases that diversify effector recognition
2009
Detailed analysis of the DNA recognition motifs of the Xanthomonas type III effectors AvrBs3 and AvrBs3Δrep16
2009
Mutations in the Pseudomonas syringae avrRpt2 gene That Dissociate Its Virulence and Avirulence Activities Lead to Decreased Efficiency in AvrRpt2-Induced Disappearance of RIN4
2004
Linking the emergence of fungal plant diseases with ecological speciation
2010
Analysis of Flagellin Perception Mediated by flg22 Receptor OsFLS2 in Rice
2008
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
2007
Defining the core Arabidopsis thaliana root microbiome
2012 StandoutNature
Direct Proteolytic Cleavage of NLRP1B Is Necessary and Sufficient for Inflammasome Activation by Anthrax Lethal Factor
2013
Identification of Pseudomonas syringae type III effectors that can suppress programmed cell death in plants and yeast
2004
Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiota
2012 StandoutNature
Plant NB-LRR Immune Receptors: From Recognition to Transcriptional Reprogramming
2008
Disabling surveillance: bacterial type III secretion system effectors that suppress innate immunity
2004
NLR functions in plant and animal immune systems: so far and yet so close
2011
CLAN, a Novel Human CED-4-like Gene
2001
Specific Bacterial Suppressors of MAMP Signaling Upstream of MAPKKK in Arabidopsis Innate Immunity
2006
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis
2006
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
2006 Standout
An Evolutionarily Conserved Mediator of Plant Disease Resistance Gene Function Is Required for Normal Arabidopsis Development
2002
Brothers in arms? Common and contrasting themes in pathogen perception by plant NB-LRR and animal NACHT-LRR proteins
2007
Tracing the ancient origins of plant innate immunity
2007
Initiation of RPS2-Specified Disease Resistance in Arabidopsis Is Coupled to the AvrRpt2-Directed Elimination of RIN4
2003
Are innate immune signaling pathways in plants and animals conserved?
2005
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
The TIR Domain of TIR-NB-LRR Resistance Proteins Is a Signaling Domain Involved in Cell Death Induction
2009
NB-LRRs work a “bait and switch” on pathogens
2009
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Early events in the pathogenicity of Pseudomonas syringae on Nicotiana benthamiana
2007
Computational and Biochemical Analysis of the Xanthomonas Effector AvrBs2 and Its Role in the Modulation of Xanthomonas Type Three Effector Delivery
2011
Strategies used by bacterial pathogens to suppress plant defenses
2004
Pattern-recognition receptors in plant innate immunity
2008
Plant innate immunity – direct and indirect recognition of general and specific pathogen-associated molecules
2003
Identification of Arabidopsis Loci Required for Susceptibility to the Downy Mildew Pathogen Hyaloperonospora parasitica
2005
Protein delivery into eukaryotic cells by type III secretion machines
2006 Nature
Intracellular NOD-like Receptors in Host Defense and Disease
2007
Emerging fungal threats to animal, plant and ecosystem health
2012 StandoutNature
Two TIR:NB:LRR genes are required to specify resistance to Peronospora parasitica isolate Cala2 in Arabidopsis
2004
Characterization of AvrBs3-Like Effectors from a Brassicaceae Pathogen Reveals Virulence and Avirulence Activities and a Protein with a Novel Repeat Architecture
2005
Innate immunity in plants and animals: striking similarities and obvious differences
2004
The Chitin-Binding Cladosporium fulvum Effector Protein Avr4 Is a Virulence Factor
2007
The AvrM Effector from Flax Rust Has a Structured C-Terminal Domain and Interacts Directly with the M Resistance Protein
2009
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Nuclear Accumulation of the Arabidopsis Immune Receptor RPS4 Is Necessary for Triggering EDS1-Dependent Defense
2007
Plant Immunity and Film Noir
2002
Resistance proteins: molecular switches of plant defence
2006
Plant Stomata Function in Innate Immunity against Bacterial Invasion
2006
The Pseudomonas syringae type III effector AvrRpt2 promotes virulence independently of RIN4, a predicted virulence target in Arabidopsis thaliana
2004
Bacterial elicitation and evasion of plant innate immunity
2006
RIN4 Functions with Plasma Membrane H+-ATPases to Regulate Stomatal Apertures during Pathogen Attack
2009
Plant targets for Pseudomonas syringae type III effectors: virulence targets or guarded decoys?
2011
Pathogen Recognition and Innate Immunity
2006 Standout
Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance
2006
Plant disease resistance protein signaling: NBS–LRR proteins and their partners
2004
The plant immune system
2006 StandoutNature
Inflammasomes in health and disease
2012 StandoutNature
Regulation of the Antimicrobial Response by NLR Proteins
2011
Direct Identification of the Meloidogyne incognita Secretome Reveals Proteins with Host Cell Reprogramming Potential
2008
A Pseudomonas syringae Effector Inactivates MAPKs to Suppress PAMP-Induced Immunity in Plants
2007
Emerging Concepts in Effector Biology of Plant-Associated Organisms
2009
Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf
2006
Epstein-Barr Virus-Encoded Bcl-2 Homologue Functions as a Survival Factor in Wp-Restricted Burkitt Lymphoma Cell Line P3HR-1
2009
The potential of effector‐target genes in breeding for plant innate immunity
2012
The Tomato NBARC-LRR Protein Prf Interacts with Pto Kinase in Vivo to Regulate Specific Plant Immunity
2006
Evolutionary History and Stress Regulation of Plant Receptor-Like Kinase/Pelle Genes
2009
Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1
2010
From Guard to Decoy: A New Model for Perception of Plant Pathogen Effectors
2008
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity
2009
Contrasting Mechanisms of Defense Against Biotrophic and Necrotrophic Pathogens
2005 Standout
Pivoting the Plant Immune System from Dissection to Deployment
2013 StandoutScience
Diverse Evolutionary Mechanisms Shape the Type III Effector Virulence Factor Repertoire in the Plant Pathogen Pseudomonas syringae
2004
Identification and Mutational Analysis of Arabidopsis FLS2 Leucine-Rich Repeat Domain Residues That Contribute to Flagellin Perception
2007
A Putative Nucleoporin 96 Is Required for Both Basal Defense and Constitutive Resistance Responses Mediated bysuppressor of npr1-1,constitutive 1
2005
TYPE III SECRETION SYSTEM EFFECTOR PROTEINS: Double Agents in Bacterial Disease and Plant Defense
2004
Understanding the Functions of Plant Disease Resistance Proteins
2003
NDR1 Interaction with RIN4 Mediates the Differential Activation of Multiple Disease Resistance Pathways in Arabidopsis
2006
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Distinct Domains in the ARC Region of the Potato Resistance Protein Rx Mediate LRR Binding and Inhibition of Activation
2006
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
A maize resistance gene functions against bacterial streak disease in rice
2005
Physical interaction between RRS1-R, a protein conferring resistance to bacterial wilt, and PopP2, a type III effector targeted to the plant nucleus
2003
Within-Species Flagellin Polymorphism inXanthomonas campestrispvcampestrisand Its Impact on Elicitation ofArabidopsis FLAGELLIN SENSING2–Dependent Defenses
2006
Plant Immunity: The Origami of Receptor Activation
2004
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Recognition and Response in the Plant Immune System
2003
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
On guard
2002 Nature
Flax Rust Resistance Gene Specificity is Based on Direct Resistance-Avirulence Protein Interactions
2007
A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae
2005
TLR5-Deficient Mice Lack Basal Inflammatory and Metabolic Defects but Exhibit Impaired CD4 T Cell Responses to a Flagellated Pathogen
2011
A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition Receptors
2009 Standout
Extracellular Vesicles Isolated from the Leaf Apoplast Carry Stress-Response Proteins
2016
The Membrane-Anchored BOTRYTIS-INDUCED KINASE1 Plays Distinct Roles in Arabidopsis Resistance to Necrotrophic and Biotrophic Pathogens
2005
Using decoys to expand the recognition specificity of a plant disease resistance protein
2016 Science
Uncoupling of sustained MAMP receptor signaling from early outputs in an Arabidopsis endoplasmic reticulum glucosidase II allele
2009
Spermidine in health and disease
2018 StandoutScience
Multiple Roles of CLAN (Caspase-Associated Recruitment Domain, Leucine-Rich Repeat, and NAIP CIIA HET-E, and TP1-Containing Protein) in the Mammalian Innate Immune Response
2004
NEW INSIGHTS TO THE FUNCTION OF PHYTOPATHOGENIC BACTERIAL TYPE III EFFECTORS IN PLANTS
2005
Establishment of an oriP Replicon Is Dependent upon an Infrequent, Epigenetic Event
2001
Recognition Specificity and RAR1/SGT1 Dependence in Barley Mla Disease Resistance Genes to the Powdery Mildew Fungus
2003
Molecular characterization of proteolytic cleavage sites of the Pseudomonas syringae effector AvrRpt2
2005
The Inflammasomes: Guardians of the Body
2009 Standout
Molecular Basis for the RIN4 Negative Regulation of RPS2 Disease Resistance
2005
A family of conserved bacterial effectors inhibits salicylic acid-mediated basal immunity and promotes disease necrosis in plants
2004
Subterfuge and Manipulation: Type III Effector Proteins of Phytopathogenic Bacteria
2006
The Transcriptional Innate Immune Response to flg22. Interplay and Overlap with Avr Gene-Dependent Defense Responses and Bacterial Pathogenesis
2004
Molecular Interactions Between Tomato and the Leaf Mold Pathogen Cladosporium fulvum
2005
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Indirect activation of a plant nucleotide binding site–leucine-rich repeat protein by a bacterial protease
2007
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
The ecology of the microbiome: Networks, competition, and stability
2015 StandoutScience
Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles
2009
The type III effector HopF2 Pto targets Arabidopsis RIN4 protein to promote Pseudomonas syringae virulence
2010
The Coiled-Coil and Nucleotide Binding Domains of the Potato Rx Disease Resistance Protein Function in Pathogen Recognition and Signaling
2008
Quantitative Interactor Screening with next-generation Sequencing (QIS-Seq) identifies Arabidopsis thaliana MLO2 as a target of the Pseudomonas syringae type III effector HopZ2
2012
Bacteria and the Aging and Longevity of Caenorhabditis elegans
2013
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Breaking the Barriers: Microbial Effector Molecules Subvert Plant Immunity
2008
Antagonistic Control of Disease Resistance Protein Stability in the Plant Immune System
2005 Science
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
RicePi5-Mediated Resistance toMagnaporthe oryzaeRequires the Presence of Two Coiled-Coil–Nucleotide-Binding–Leucine-Rich Repeat Genes
2009
ESTABLISHMENT OF BIOTROPHY BY PARASITIC FUNGI AND REPROGRAMMING OF HOST CELLS FOR DISEASE RESISTANCE
2003
Structure and Functions of the Bacterial Microbiota of Plants
2013 Standout
Transcript Profiling in Host–Pathogen Interactions
2007
Lipid signalling in plant responses to abiotic stress
2015
The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells
2007
CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases
2004
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of David Mackey being referenced
Arabidopsis RIN4 Negatively Regulates Disease Resistance Mediated by RPS2 and RPM1 Downstream or Independent of the NDR1 Signal Modulator and Is Not Required for the Virulence Functions of Bacterial Type III Effectors AvrRpt2 or AvrRpm1
2004
Arabidopsis RIN4 Is a Target of the Type III Virulence Effector AvrRpt2 and Modulates RPS2-Mediated Resistance
2003
The Pseudomonas syringae type III effector AvrRpm1 induces significant defenses by activating the Arabidopsis nucleotide‐binding leucine‐rich repeat protein RPS2
2008
RIN4 Interacts with Pseudomonas syringae Type III Effector Molecules and Is Required for RPM1-Mediated Resistance in Arabidopsis
2002
Specific Threonine Phosphorylation of a Host Target by Two Unrelated Type III Effectors Activates a Host Innate Immune Receptor in Plants
2011
WtsE, an AvrE-Family Effector Protein from Pantoea stewartii subsp. stewartii, Causes Disease-Associated Cell Death in Corn and Requires a Chaperone Protein for Stability
2006
The phytotoxin coronatine is a multifunctional component of the virulence armament of Pseudomonas syringae
2014
MAMPs and MIMPs: proposed classifications for inducers of innate immunity
2006
Phospholipase‐dependent signalling during the AvrRpm1‐ and AvrRpt2‐induced disease resistance responses in Arabidopsis thaliana
2006
Defense suppression by virulence effectors of bacterial phytopathogens
2007
Recognition of pathogens by plants
2000
Two Pseudomonas syringae Type III Effectors Inhibit RIN4-Regulated Basal Defense in Arabidopsis
2005
Layered basal defenses underlie non‐host resistance of Arabidopsis to Pseudomonas syringae pv. phaseolicola
2007
The Linking Regions of EBNA1 Are Essential for Its Support of Replication and Transcription
1999
Elicitors, Effectors, and R Genes: The New Paradigm and a Lifetime Supply of Questions
2007
Contrasting Roles of the Apoplastic Aspartyl Protease APOPLASTIC, ENHANCED DISEASE SUSCEPTIBILITY1-DEPENDENT1 and LEGUME LECTIN-LIKE PROTEIN1 in Arabidopsis Systemic Acquired Resistance ,
2014