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Selection of the T-cell repertoire in transgenic mice expressing a transplantation antigen in distinct thymus subsets
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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers.
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1995
Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen
1991
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1999
IκBα Deficiency Results in a Sustained NF-κB Response and Severe Widespread Dermatitis in Mice
1996
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Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus.
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2001
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Alpha/beta T-cell antigen receptor gene and protein expression occurs at early stages of thymocyte differentiation.
1988 StandoutNobel
In vivo induction of antigen-specific transplantation tolerance to Qa1a by exposure to alloantigen in the absence of T-cell help.
1990
High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes
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Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
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2004
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The T Cell Receptor
1987 Science
Immunobiology of Dendritic Cells
2000 Standout
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.
1996
The Instructive Role of Innate Immunity in the Acquired Immune Response
1996 Science
The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells
1990 Science
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes
2002
Persistence of Physiological Self Antigen Is Required for the Regulation of Self Tolerance
2000
Activation events during thymic selection.
1992
Intrathymic differentiation of V gamma 3 T cells.
1993 StandoutNobel
Tolerogenic Dendritic Cells
2003 StandoutNobel
Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8+ T Cells
1997
CD1: Antigen Presentation and T Cell Function
2004
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages.
1990
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2002
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1996 StandoutScienceNobel
Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo
2000
Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.
1990
In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses
2005
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Heat-stable antigen is a costimulatory molecule for CD4 T cell growth.
1992
Immunological Memory and Protective Immunity: Understanding Their Relation
1996 StandoutScience
Induction by Antigen of Intrathymic Apoptosis of CD4 + CD8 + TCR lo Thymocytes in Vivo
1990 StandoutScience
Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50
1998
Medullary Thymic Epithelium: A Mosaic of Epithelial “Self”?
1998
CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells
1998
A Skin Homing Molecule Defines the Langerhans Cell Progenitor in Human Peripheral Blood
1997
Enhanced Pathogenicity of Diabetogenic T Cells Escaping a Non-MHC Gene-Controlled Near Death Experience
2004
On the complexity of self
1991 Nature
Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.
1989
Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.
1993 StandoutNobel
Immunotherapy by peptides?
1989 Nature
Role of Bone Marrow-Derived Cells in Presenting MHC Class I-Restricted Tumor Antigens
1994 Science
CELL BIOLOGY OF ANTIGEN PROCESSING IN VITRO AND IN VIVO
2005
A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells
1996
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1999
Dendritic-Like Cells from relB Mutant Mice
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On the various manifestations of spontaneous autoimmune diabetes in rodent models
1994
Clonal Anergy of I-E-tolerant T Cells in Transgenic Mice with Pancreatic Expression of MHC Class II I-E
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A novel MHC class II epitope expressed in thymic medulla but not cortex
1989 Nature
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
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Expression of relB is required for the development of thymic medulla and dendritic cells
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Peripheral tolerance to an islet cell‐specific hemagglutinin transgene affects both CD4+ and CD8+ T cells
1992
T Cell Selection in the Thymus
1988
Thymic stromal cell specialization and the T-cell receptor repertoire
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Abnormal differentiation of thymocytes in mice treated with cyclosporin A
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Tolerance in Transgenic Mice Expressing Major Histocompatibility Molecules Extrathymically on Pancreatic Cells
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Among naive precursor cell subpopulations only progenitors of memory B cells originate germinal centers
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In Vivo Inhibition of CC and CX3C Chemokine–induced Leukocyte Infiltration and Attenuation of Glomerulonephritis in Wistar-Kyoto (WKY) Rats by vMIP-II
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Cutting Edge: Ectopic Expression of the Chemokine TCA4/SLC Is Sufficient to Trigger Lymphoid Neogenesis
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c-maf Promotes T Helper Cell Type 2 (Th2) and Attenuates Th1 Differentiation by Both Interleukin 4–dependent and –independent Mechanisms
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NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14i NKT Cells
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