Citation Impact
Citing Papers
Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity
2013 StandoutNobel
Two Atypical l-Cysteine-regulated NADPH-dependent Oxidoreductases Involved in Redox Maintenance, l-Cystine and Iron Reduction, and Metronidazole Activation in the Enteric Protozoan Entamoeba histolytica
2010
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
2023 Standout
Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis
2020 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
2021 Standout
Hfq structure, function and ligand binding
2007
Identification of Bacteriophage-Encoded Anti-sRNAs in Pathogenic Escherichia coli
2014
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
A novel Hfq‐dependent sRNA that is under FNR control and is synthesized in oxygen limitation in Neisseria meningitidis
2011
Identification of natural inhibitors of Entamoeba histolytica cysteine synthase from microbial secondary metabolites
2015 StandoutNobel
MicroReview: The bacterial Sm‐like protein Hfq: a key player in RNA transactions
2004
RNA Chaperones, RNA Annealers and RNA Helicases
2007
DNA recognition by an RNA-guided bacterial Argonaute
2017 StandoutNobel
An overview of RNAs with regulatory functions in gram-positive bacteria
2009 StandoutNobel
The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics
2020 Standout
Small RNA Regulators and the Bacterial Response to Stress
2006
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
Quorum sensing signal–response systems in Gram-negative bacteria
2016 Standout
Hfq and its constellation of RNA
2011
Deconjugated Bile Salts Produced by Extracellular Bile-Salt Hydrolase-Like Activities from the Probiotic Lactobacillus johnsonii La1 Inhibit Giardia duodenalis In vitro Growth
2016
The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNA
2008
The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal
2011
Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways
2012 StandoutNobel
Planting the seed: target recognition of short guide RNAs
2014
Controlling mRNA stability and translation with small, noncoding RNAs
2004
Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control
2012 Standout
Non-coding RNA
2006 Standout
Glycomics, Glycoproteomics, and Glycogenomics: An Inter-Taxa Evolutionary Perspective
2020
The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq
2012
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
The C-terminal domain of Escherichia coli Hfq is required for regulation
2007
RNA sequencing uncovers antisense RNAs and novel small RNAs inStreptococcus pyogenes
2015 StandoutNobel
Bacterial Small RNA Regulators
2005
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Functional Diversity of AAA+ Protease Complexes in Bacillus subtilis
2017 StandoutNobel
Glycoproteomics
2022 StandoutNobel
In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes
2018 StandoutNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Characterization of a transcriptional TPP riboswitch in the human pathogen Neisseria meningitidis
2020 StandoutNobel
Non-Antibiotic Drug Repositioning as an Alternative Antimicrobial Approach
2022
Impaired Parasite Attachment as Fitness Cost of Metronidazole Resistance in Giardia lamblia
2011
Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia
2017 StandoutNobel
Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes
2012
The Small RNA Regulators ofEscherichia coli: Roles and Mechanisms
2004
Management of Oxidative Stress in Bacillus
2009
Antiprotozoal Constituents from Annona cherimola Miller, a Plant Used in Mexican Traditional Medicine for the Treatment of Diarrhea and Dysentery.
2017
Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health
2020 Standout
Analog sensitive chemical inhibition of the DEAD ‐box protein DDX 3
2015 StandoutNobel
Human protein paucimannosylation: cues from the eukaryotic kingdoms
2019
Bacterial Quorum-Sensing Network Architectures
2009 Standout
The Hfq-Dependent Small Noncoding RNA NrrF Directly Mediates Fur-Dependent Positive Regulation of Succinate Dehydrogenase in Neisseria meningitidis
2008
Giardia , Entamoeba , and Trichomonas Enzymes Activate Metronidazole (Nitroreductases) and Inactivate Metronidazole (Nitroimidazole Reductases)
2008
Works of David Leitsch being referenced
A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia
2013
Drug Resistance in the Microaerophilic Parasite Giardia lamblia
2015
Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target
2016
Nitroimidazole Action in Entamoeba histolytica: A Central Role for Thioredoxin Reductase
2007
The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways
2010
The N-glycans of Trichomonas vaginalis contain variable core and antennal modifications
2011
Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds
2015
Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance
2009
Nitroimidazole drugs vary in their mode of action in the human parasite Giardia lamblia
2012
Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia
2011
RNA chaperone activity of the Sm‐like Hfq protein
2003