Citation Impact
Citing Papers
Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling
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An Extensive Class of Small RNAs in Caenorhabditis elegans
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2004
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1998 Nature
Hallmarks of Cancer: The Next Generation
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Drosophila Tcf and Groucho interact to repress Wingless signalling activity
1998 Nature
Expression and function of Drosophila cyclin a during embryonic cell cycle progression
1989
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1991
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
2005 Nature
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
2004
Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication
1994
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos
1992 Nature
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Axin and Frat1 interact with Dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1
1999
Structural basis of the Axin–adenomatous polyposis coli interaction
2000
MicroRNAs
2004 Standout
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1998 Standout
β-catenin: a key mediator of Wnt signaling
1998
A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β
1987
Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
1998
Cytoplasmically Anchored Plakoglobin Induces a WNT-like Phenotype inXenopus
1997
Distribution of FGF‐2 suggests it has a role in chick limb bud growth
1993
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
1994
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1993
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1991
Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
2008 Standout
Regulation of GSK-3
2001
Feedback control of mitosis in budding yeast
1991
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Competition between chromatin and transcription complex assembly regulates gene expression during early development
1994
Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer
2004
Axin-dependent Phosphorylation of the Adenomatous Polyposis Coli Protein Mediated by Casein Kinase 1ε
2001
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4
1996 Standout
Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin
1997
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
2006
Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: Studies in Xenopus
1990
The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell
1999
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures
1990
Roles of Axin in the Wnt Signalling Pathway
1999
Pygopus, a nuclear PHD-finger protein required for Wingless signaling inDrosophila
2002
A common human skin tumour is caused by activating mutations in β-catenin
1999
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
1998
Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth
2004 Nobel
Inducing factors in Xenopus early embryos
1994
Involvement of p21ras in Xenopus mesoderm induction
1992 Nature
Creative blocks: cell-cycle checkpoints and feedback controls
1992 Nature
Propagation and localization of Wnt signaling
1998
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
1990 StandoutNobel
Mesoderm induction in Xenopus caused by activation of MAP kinase
1995 Nature
Neural and developmental actions of lithium: A unifying hypothesis
1989 Standout
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1998 StandoutNatureNobel
Crystal Structure of Glycogen Synthase Kinase 3β
2001
WNTs modulate cell fate and behavior during vertebrate development
1997
Transcription under the Control of Nuclear Arm/β-Catenin
2006
Regulation of β-Catenin Signaling in the Wnt Pathway
2000
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
1998 Nature
Wnt Signaling and the Polarity of the Primary Body Axis
2009
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
1996 StandoutNature
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
1991 StandoutNatureNobel
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The renaissance of GSK3
2001
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
2000 StandoutNatureNobel
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
1999 Nature
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development
1995
A Mechanism for Wnt Coreceptor Activation
2004
A GSK3β Phosphorylation Site in Axin Modulates Interaction with β-Catenin and Tcf-Mediated Gene Expression
1999
Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
2012
Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin
1998
Cellular targets for transformation by the adenovirus E1A proteins
1989
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling
2005
Measurement of developmental time by cells of early embryos
1990
LEF-1, a Nuclear Factor Coordinating Signaling Inputs from wingless and decapentaplegic
1997
Direct and Long-Range Action of a Wingless Morphogen Gradient
1996
Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos
1989
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Protein kinase C mediates neural induction in Xenopus laevis
1988 Nature
A region of SV40 large T antigen can substitute for a transforming domain of the adenovirus E1A products
1988 Nature
Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification
2010
The Casein Kinase I Family in Wnt Signaling
2001
Three-Dimensional Structure of the Armadillo Repeat Region of β-Catenin
1997
The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor
1996
Structural and Functional Diversity in the FGf Receptor Multigene Family
1992
β-catenin is a target for the ubiquitin–proteasome pathway
1997 Standout
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Dorsalization of mesoderm induction by lithium
1989
CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling
2006
A GSK3‐binding peptide from FRAT1 selectively inhibits the GSK3‐catalysed phosphorylation of Axin and β‐catenin
1999
Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
1998 Nature
Monounsaturated Fatty Acid Modification of Wnt Protein: Its Role in Wnt Secretion
2006
Wnt and calcium signaling: β-Catenin-independent pathways
2005
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
1992
High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5
2002
Signal transduction through beta-catenin and specification of cell fate during embryogenesis.
1996
Control of the yeast cell cycle by the Cdc28 protein kinase
1993
Differential Regulation of Glycogen Synthase Kinase 3β by Insulin and Wnt Signaling
2000
Mesodermal induction in early amphibian embryos by activin A (erythroid differentiation factor)
1990
Wnt-induced dephosphorylation of Axin releases beta -catenin from the Axin complex
1999
Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling
2009
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
1988
Maternal Wnt11 Activates the Canonical Wnt Signaling Pathway Required for Axis Formation in Xenopus Embryos
2005
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin
1998
Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog
1989
A new nuclear component of the Wnt signalling pathway
2002
Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A
1990 Nature
The molecular genetics of embryonic pattern formation in Drosophila
1988 StandoutNature
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer
1996 Nature
Armadillo and dTCF: a marriage made in the nucleus
1997 Standout
Control of β-Catenin Stability
2000
A model for familial exudative vitreoretinopathy caused by LPR5 mutations
2008 StandoutNobel
LRP5 Mutations Linked to High Bone Mass Diseases Cause Reduced LRP5 Binding and Inhibition by SOST
2006
Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF
1993
Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud
1994 Standout
Germinal vesicle components are not required for the cell-cycle oscillator of the early starfish embryo
1988
A common plan for dorsoventral patterning in Bilateria
1996 Nature
Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development
1998 Nobel
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
The adenomatous polyposis coli (APC) tumor suppressor
1997
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
1993 StandoutNobel
An LRP5 Receptor with Internal Deletion in Hyperparathyroid Tumors with Implications for Deregulated WNT/β-Catenin Signaling
2007
Role of the LIM class homeodomain protein Xlim-1 in neural and muscle induction by the Spemann organizer in Xenopus
1994 Nature
Processed Vg1 protein is an axial mesoderm inducer in xenopus
1993
Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice
1999
Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid
1991
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
1996
LEF-1/TCF Proteins Mediate Wnt-Inducible Transcription from the Xenopus Nodal-Related 3 Promoter
1997
Cell adhesion and signal transduction: the Armadillo connection
1995
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
2000 StandoutNatureNobel
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex
2010 Nature
The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo
1994
β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
2005
Activin receptor mRNA is expressed early in Xenopus embryogenesis and the level of the expression affects the body axis formation
1991
The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4
1996
The Sp1-Related Transcription Factors sp5 and sp5-like Act Downstream of Wnt/β-Catenin Signaling in Mesoderm and Neuroectoderm Patterning
2005
The Mouse Locus Encodes Axin, an Inhibitor of the Wnt Signaling Pathway That Regulates Embryonic Axis Formation
1997
Thermodynamics of β-Catenin-Ligand Interactions
2005
A computer model to dynamically simulate protein folding: Studies with crambin
1989
Wnt signaling: why is everything so negative?
1998
Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
1994
The Novel Tyrosine Kinase ZAK1 Activates GSK3 to Direct Cell Fate Specification
1999
What makes an mRNA anti-sensi-itive?
1993
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
2010
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
1998 StandoutNature
Regulation of the Mid-Blastula Transition in Amphibians
1988
The functions of animal microRNAs
2004 StandoutNatureNobel
The APC tumour suppressor has a nuclear export function
2000 Nature
A Common Phosphate Binding Site Explains the Unique Substrate Specificity of GSK3 and Its Inactivation by Phosphorylation
2001
Casein kinase I transduces Wnt signals
1999 Nature
Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene
1999
Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
1992
Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction
2005 Nature
Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes
2010
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Activation of the Wnt Signaling Pathway: A Molecular Mechanism for Lithium Action
1997
Phosphorylation of Axin, a Wnt Signal Negative Regulator, by Glycogen Synthase Kinase-3β Regulates Its Stability
1999
The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
1999 Nature
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
2000
Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation
1993
Identification of connexin43 as a functional target for Wnt signalling
1998
Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos
1996
Regulation of the fibroblast growth factor receptor in early Xenopus embryos.
1990
β-Trcp couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation
1999
Fgf-4expression during gastrulation, myogenesis, limb and tooth development in the mouse
1992
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern
1994
Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis
1992
A Drosophila Axin homolog, Daxin, inhibits Wnt signaling
1999
Mammalian DNA ligases. Catalytic domain and size of DNA ligase I.
1990 StandoutNobel
Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of β-catenin
2004
The hedgehog gene family in Drosophila and vertebrate development
1994
A molecular mechanism for the effect of lithium on development.
1996 Standout
On the coupling between DNA replication and mitosis
1989
Pontin52, an interaction partner of β-catenin, binds to the TATA box binding protein
1998
Directing Cell Division During Development
1989 Science
Analysis of the Signaling Activities of Localization Mutants of β-Catenin during Axis Specification in Xenopus
1997
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.
1991
Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors
1988 Science
Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern
1994
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
2002
Effects of Forced Expression of an NH2-terminal Truncated β-Catenin on Mouse Intestinal Epithelial Homeostasis
1998
Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines
1997 Science
Mesoderm induction by activin requires FGF-mediated intracellular signals
1994
The release of growth arrest by microinjection of adenovirus E1A DNA.
1985
Reduced Affinity to and Inhibition by DKK1 Form a Common Mechanism by Which High Bone Mass-Associated Missense Mutations in LRP5 Affect Canonical Wnt Signaling
2005
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Bridging of β-catenin and glycogen synthase kinase-3β by Axin and inhibition of β-catenin-mediated transcription
1998
Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle
1991 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Wnt signaling and cancer
2000 Standout
The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.
1994
Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expression
2008
Expression of a novel FGF in theXenopusembryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification
1992
Judging a Protein by More Than Its Name: GSK-3
2001
Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β
1998 Science
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways
1998
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way
2004
Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products.
1987 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
A Member of the Frizzled Protein Family Mediating Axis Induction by Wnt-5A
1997 Science
Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction
1998
The causal analysis of development in the past half century: a personal history
1992
Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas
1998
Maternal mRNA from clam oocytes can be specifically unmasked in vitro by antisense RNA complementary to the 3'-untranslated region.
1990 StandoutNobel
Cooperation between the activin and Wnt pathways in the spatial control of organizer gene expression
1998 StandoutNobel
Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps.
1996
Wise, a context-dependent activator and inhibitor of Wnt signalling
2003
Physiological regulation of β-catenin stability by Tcf3 and CK1ϵ
2001
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
1999 Standout
Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.
1995
Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.
1991
eFGF regulates Xbra expression during Xenopus gastrulation.
1994
Ectopic expression of the H19 gene in mice causes prenatal lethality.
1991 StandoutNobel
Novel Regulators of Bone Formation: Molecular Clones and Activities
1988 StandoutScience
MECHANISMS OF WNT SIGNALING IN DEVELOPMENT
1998 Standout
Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development
1989
Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.
1995
The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation
1996 StandoutNobel
Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1.
1993
On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.
1994
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
Intercellular signaling and gene regulation during early embryogenesis of Xenopus laevis.
1994
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex.
1996 StandoutNobel
On the prediction of protein structure: The significance of the root-mean-square deviation
1980
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
Roles of plakoglobin end domains in desmosome assembly
1997
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
1999 Standout
Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin
1998
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
2005
Two regions of the adenovirus early region 1A proteins are required for transformation
1988
Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis.
1991
Regulation of β-Catenin Levels and Localization by Overexpression of Plakoglobin and Inhibition of the Ubiquitin-Proteasome System
1997
Inhibition of β-catenin-mediated transactivation by cadherin derivatives
1998
Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.
1988
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development.
1995
Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern
1995
Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation.
1987
Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development
1992
Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation.
1995 StandoutNobel
Functional domains of adenovirus type 5 E1a proteins
1987
Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8.
1994
The role of Axin2 in calvarial morphogenesis and craniosynostosis
2005
Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryos
1991
The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA.
1995
The role of fibroblast growth factor in early Xenopus development
1989
THE UBIQUITIN SYSTEM
1998 StandoutNobel
The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation
1992
Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products
1985
The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product
1989 StandoutScience
Plakoglobin Suppresses Epithelial Proliferation and Hair Growth in Vivo
2000 StandoutNobel
A lattice model for protein structure prediction at low resolution.
1992 StandoutNobel
Mesoderm-inducing factors in early vertebrate development.
1993
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus.
1995 StandoutNobel
Interaction of Dishevelled and Xenopus Axin-Related Protein Is Required for Wnt Signal Transduction
2000
Conversion of a mesodermalizing molecule, the Xenopus Brachyury gene, into a neuralizing factor.
1994
Works of David Kimelman being referenced
Glycogen Synthase Kinase-3β Mutagenesis Identifies a Common Binding Domain for GBP and Axin
2002
Crystal Structure of a β-Catenin/Tcf Complex
2000
Low-Density Lipoprotein Receptor-Related Protein-5 Binds to Axin and Regulates the Canonical Wnt Signaling Pathway
2001
Activation ofSiamoisby theWntPathway
1996
The Crystal Structure of the β-Catenin/ICAT Complex Reveals the Inhibitory Mechanism of ICAT
2002
β-Catenin destruction complex: insights and questions from a structural perspective
2006
Localized BMP-4 Mediates Dorsal/Ventral Patterning in the Early Xenopus Embryo
1995
Crystal structure of a β-catenin/Axin complex suggests a mechanism for the β-catenin destruction complex
2003
Wnt Signaling and the Evolution of Embryonic Posterior Development
2009
Crystal Structure of a β-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function
2004
Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development
2003
GBP, an Inhibitor of GSK-3, Is Implicated in Xenopus Development and Oncogenesis
1998
Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo
1987
Regulation of Canonical Wnt Signaling by Brachyury Is Essential for Posterior Mesoderm Formation
2008
Conservation of intracellular Wnt signaling components in dorsal-ventral axis formation in zebrafish
1999
Tcf4 can specifically recognize beta-catenin using alternative conformations.
2001
A β-catenin/XTcf-3 complex binds to thesiamois promoter to regulate dorsal axis specification in Xenopus
1997
Gravin regulates mesodermal cell behavior changes required for axis elongation during zebrafish gastrulation
2007
An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes
1989
Overexpression of Xgsk-3 Disrupts Anterior Ectodermal Patterning inXenopus
1996
From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus
1998
A homeobox gene essential for zebrafish notochord development
1995 Nature
The Role of Fibroblast Growth Factor in Early Xenopus Development
1991
Mesoderm induction: from caps to chips
2006
Fibroblast growth factor, but not activin, is a potentactivator of mitogen-activated protein kinase in Xenopusexplants.
1994
Role of Glycogen Synthase Kinase-3β in Neuronal Apoptosis Induced by Trophic Withdrawal
2000
Synthesis in Escherichia coli of human adenovirus type 12 transforming proteins encoded by early region 1A 13S mRNA and 12S mRNA.
1984
Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox
1996
Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene.
1993
A Novel General Approach to Eucaryotic Mutagenesis Functionally Identifies Conserved Regions within the Adenovirus 13S E1A Polypeptide
1986
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.
1996
The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle
1987
Establishment of the Dorso-ventral Axis in Xenopus Embryos Is Presaged by Early Asymmetries in β-Catenin That Are Modulated by the Wnt Signaling Pathway
1997
Identification of adenovirus 12-encoded E1A tumor antigens synthesized in infected and transformed mammalian cells and in Escherichia coli
1984
Induction of dorsal and ventral mesoderm by ectopically expressed Xenopus basic fibroblast growth factor
1992
Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction
1992
The homeobox genesvoxandventare redundant repressors of dorsal fates in zebrafish
2001
Calculation of protein tertiary structure
1976
Interaction among Gsk-3, Gbp, Axin, and APC in Xenopus Axis Specification
2000
Activin-mediated mesoderm induction requires FGF
1994
Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation
2004
Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning
1995
E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related
1985
FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction
1995
Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3
1995
Mechanistic insights from structural studies of β-catenin and its binding partners
2007
Activin-mediated mesoderm induction requires FGF
1994
Move it or lose it: axis specification in Xenopus
2004
XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development
1999
Production of a monospecific antiserum against the early region 1A proteins of adenovirus 12 and adenovirus 5 by an adenovirus 12 early region 1A-beta-galactosidase fusion protein antigen expressed in bacteria
1984
Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression
1985
The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer
1988 Science