Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
Chemoreceptor Hypersensitivity, Sympathetic Excitation, and Overexpression of ASIC and TASK Channels Before the Onset of Hypertension in SHR
2009
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease
2019
A fluorescent probe designed for studying protein conformational change
2005 StandoutNobel
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats
2005
Crystal Structure of the Second LNS/LG Domain from Neurexin 1α
2006 StandoutNobel
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Reversal of acid‐induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
2010
A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel
2010
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation
2012
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Acid-sensing Ion Channels in Sensory Perception
2007
TRPV1: a therapeutic target for novel analgesic drugs?
2006
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Plasticity of pain signaling: Role of neurotrophic factors exemplified by acid‐induced pain
2004
Characterization of a Ligand Binding Site in the Human Transient Receptor Potential Ankyrin 1 Pore
2013
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Transient receptor potential ion channels as participants in thermosensation and thermoregulation
2006
Proton Activation Does Not Alter Antagonist Interaction with the Capsaicin-Binding Pocket of TRPV1
2005
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain
2010
Targeting TRP channels for pain relief
2013
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
Biochemistry and pharmacology of endovanilloids
2007
Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
2008 StandoutNobel
Characterization of Acid-sensing Ion Channels in Dorsal Horn Neurons of Rat Spinal Cord
2004
The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4
2015
Receptor-targeting mechanisms of pain-causing toxins: How ow?
2012 StandoutNobel
TRPV1 Is Activated by Both Acidic and Basic pH
2009 StandoutNobel
Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
2008
TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists
2006
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
TRPA1 antagonists as potential analgesic drugs
2011
Identification of Molecular Determinants for a Potent Mammalian TRPA1 Antagonist by Utilizing Species Differences
2013
A Polyclonal Antibody to the Prepore Loop of Transient Receptor Potential Vanilloid Type 1 Blocks Channel Activation
2006
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH
2007 Nature
TRPV1
2014
Neuroprotection in Ischemia
2004
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Extracellular Cations Sensitize and Gate Capsaicin Receptor TRPV1 Modulating Pain Signaling
2005
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
K+/Na+ selectivity of the KcsA potassium channel from microscopic free energy perturbation calculations
2001
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors
2016
Reconstructing Voltage Sensor–Pore Interaction from a Fluorescence Scan of a Voltage-Gated K+ Channel
2000
Acid-sensing ion channels: advances, questions and therapeutic opportunities
2006
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
2006
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
2009 Nature
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid‐sensitive channel in sensory neurons
2004
Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2
2008
Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1
2008
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
The receptor site of the spider toxin PcTx1 on the proton‐gated cation channel ASIC1a
2005
Calcium Signaling
2007 Standout
Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization
2017 StandoutNobel
TRPA1 as a drug target—promise and challenges
2015
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Recordings from Single Neocortical Nerve Terminals Reveal a Nonselective Cation Channel Activated by Decreases in Extracellular Calcium
2004
7-tert-Butyl-6-(4-Chloro-Phenyl)-2-Thioxo-2,3-Dihydro-1H-Pyrido[2,3-d]Pyrimidin-4-One, a Classic Polymodal Inhibitor of Transient Receptor Potential Vanilloid Type 1 with a Reduced Liability for Hyperthermia, Is Analgesic and Ameliorates Visceral Hypersensitivity
2012
The Met268Pro Mutation of Mouse TRPA1 Changes the Effect of Caffeine from Activation to Suppression
2010
The Tarantula Toxin Psalmotoxin 1 Inhibits Acid-sensing Ion Channel (ASIC) 1a by Increasing Its Apparent H+ Affinity
2005
Structure and activity of the acid-sensing ion channels
2012
Lactate – a signal coordinating cell and systemic function
2005
Discovery, Optimization, and Biological Evaluation of 5-(2-(Trifluoromethyl)phenyl)indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists
2014 StandoutNobel
Interaction of Acid-sensing Ion Channel (ASIC) 1 with the Tarantula Toxin Psalmotoxin 1 is State Dependent
2006
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.
2010
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Realistic simulation of the activation of voltage-gated ion channels
2012 StandoutNobel
Distinct Mechanosensitive Properties of Capsaicin-Sensitive and -Insensitive Sensory Neurons
2002
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
TRPA1 and Cold Transduction: An Unresolved Issue?
2009
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
The Roles of iPLA2, TRPM8 and TRPA1 in Chemically Induced Cold Hypersensitivity
2010
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents
2010
Works of David Immke being referenced
Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons
2001
Protons Open Acid-Sensing Ion Channels by Catalyzing Relief of Ca2+ Blockade
2003
The TRPV1 receptor and nociception
2006
Structure–activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonists
2010
AMG 9810 [(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a Novel Vanilloid Receptor 1 (TRPV1) Antagonist with Antihyperalgesic Properties
2005
ASIC3: A Lactic Acid Sensor for Cardiac Pain
2001
Species-Specific Pharmacology of Trichloro(Sulfanyl)ethyl Benzamides as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists
2007
Potassium-dependent Changes in the Conformation of the Kv2.1 Potassium Channel Pore
1999
The Interaction of Na+ and K+ in Voltage-gated Potassium Channels
1998
ASIC3, an Acid-Sensing Ion Channel, is Expressed in Metaboreceptive Sensory Neurons
2005